Institut für Medizinische Statistik

[["dc.bibliographiccitation.firstpage","143"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Microscopy"],["dc.bibliographiccitation.lastpage","148"],["dc.bibliographiccitation.volume","184"],["dc.contributor.author","Schrader, M."],["dc.contributor.author","Hell, Stefan W."],["dc.date.accessioned","2022-03-01T11:47:10Z"],["dc.date.available","2022-03-01T11:47:10Z"],["dc.date.issued","2003"],["dc.identifier.doi","10.1111/jmi.1996.184.3.143"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/103937"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-531"],["dc.relation.issn","0022-2720"],["dc.title","Wavefronts in the focus of a light microscope"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","798"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Musculoskeletal Disorders"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Prediger, Barbara"],["dc.contributor.author","Tjardes, Thorsten"],["dc.contributor.author","Probst, Christian"],["dc.contributor.author","Heu-Parvaresch, Anahieta"],["dc.contributor.author","Glatt, Angelina"],["dc.contributor.author","Dos Anjos, Dominique Rodil"],["dc.contributor.author","Bouillon, Bertil"],["dc.contributor.author","Mathes, Tim"],["dc.date.accessioned","2021-10-27T14:32:36Z"],["dc.date.available","2021-10-27T14:32:36Z"],["dc.date.issued","2021-09-16"],["dc.description.abstract","We assessed predictive factors of patients with fractures of the lower extremities caused by trauma. We examined which factors are associated with an increased risk of failure. Furthermore, the predictive factors were set into context with other long-term outcomes, concrete pain and physical functioning."],["dc.identifier.doi","10.1186/s12891-021-04688-6"],["dc.identifier.pmid","34530793"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92140"],["dc.language.iso","en"],["dc.relation.eissn","1471-2474"],["dc.title","Factors predicting failure of internal fixations of fractures of the lower limbs: a prospective cohort study"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","403"],["dc.bibliographiccitation.issue","23"],["dc.bibliographiccitation.journal","Deutsches Ärzteblatt international"],["dc.bibliographiccitation.lastpage","404"],["dc.bibliographiccitation.volume","118"],["dc.contributor.author","Schwarz, Sarah Bettina"],["dc.contributor.author","Wollsching-Strobel, Maximilian"],["dc.contributor.author","Majorski, Daniel Sebastian"],["dc.contributor.author","Magnet, Friederike Sophie"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Windisch, Wolfram"],["dc.date.accessioned","2021-10-27T14:31:38Z"],["dc.date.available","2021-10-27T14:31:38Z"],["dc.date.issued","2021-06-11"],["dc.identifier.doi","10.3238/arztebl.m2021.0193"],["dc.identifier.pmid","34304756"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92125"],["dc.language.iso","en"],["dc.relation.issn","1866-0452"],["dc.title","The Development of Inpatient Initiation and Follow-up of Home Mechanical Ventilation in Germany"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e6399"],["dc.bibliographiccitation.journal","PeerJ"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Bravo, Gustavo A."],["dc.contributor.author","Antonelli, Alexandre"],["dc.contributor.author","Bacon, Christine D."],["dc.contributor.author","Bartoszek, Krzysztof"],["dc.contributor.author","Blom, Mozes P. K."],["dc.contributor.author","Huynh, Stella"],["dc.contributor.author","Jones, Graham"],["dc.contributor.author","Knowles, L. Lacey"],["dc.contributor.author","Lamichhaney, Sangeet"],["dc.contributor.author","Marcussen, Thomas"],["dc.contributor.author","Morlon, Hélène"],["dc.contributor.author","Nakhleh, Luay K."],["dc.contributor.author","Oxelman, Bengt"],["dc.contributor.author","Pfeil, Bernard"],["dc.contributor.author","Schliep, Alexander"],["dc.contributor.author","Wahlberg, Niklas"],["dc.contributor.author","Werneck, Fernanda P."],["dc.contributor.author","Wiedenhoeft, John"],["dc.contributor.author","Willows-Munro, Sandi"],["dc.contributor.author","Edwards, Scott V."],["dc.date.accessioned","2019-08-01T13:00:36Z"],["dc.date.available","2019-08-01T13:00:36Z"],["dc.date.issued","2019"],["dc.description.abstract","Building the Tree of Life (ToL) is a major challenge of modern biology, requiring advances in cyberinfrastructure, data collection, theory, and more. Here, we argue that phylogenomics stands to benefit by embracing the many heterogeneous genomic signals emerging from the first decade of large-scale phylogenetic analysis spawned by high-throughput sequencing (HTS). Such signals include those most commonly encountered in phylogenomic datasets, such as incomplete lineage sorting, but also those reticulate processes emerging with greater frequency, such as recombination and introgression. Here we focus specifically on how phylogenetic methods can accommodate the heterogeneity incurred by such population genetic processes; we do not discuss phylogenetic methods that ignore such processes, such as concatenation or supermatrix approaches or supertrees. We suggest that methods of data acquisition and the types of markers used in phylogenomics will remain restricted until a posteriori methods of marker choice are made possible with routine whole-genome sequencing of taxa of interest. We discuss limitations and potential extensions of a model supporting innovation in phylogenomics today, the multispecies coalescent model (MSC). Macroevolutionary models that use phylogenies, such as character mapping, often ignore the heterogeneity on which building phylogenies increasingly rely and suggest that assimilating such heterogeneity is an important goal moving forward. Finally, we argue that an integrative cyberinfrastructure linking all steps of the process of building the ToL, from specimen acquisition in the field to publication and tracking of phylogenomic data, as well as a culture that values contributors at each step, are essential for progress."],["dc.identifier.doi","10.7717/peerj.6399"],["dc.identifier.pmid","30783571"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62253"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","2167-8359"],["dc.title","Embracing heterogeneity: coalescing the Tree of Life and the future of phylogenomics"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Kück, Fabian"],["dc.contributor.author","Schuhmacher, Dominic"],["dc.contributor.author","Sturm, Anja"],["dc.creator.author","Fabian Kück"],["dc.creator.author","Dominic Schuhmacher"],["dc.creator.author","Dominic Schuhmacher"],["dc.creator.author","Anja Sturm"],["dc.date.accessioned","2022-09-08T06:29:42Z"],["dc.date.available","2022-09-08T06:29:42Z"],["dc.date.issued","2018"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114196"],["dc.language.iso","en"],["dc.publisher","Niedersächsische Staats- und Universitätsbibliothek Göttingen"],["dc.publisher.place","Göttingen"],["dc.title","Convergence Rates in Dynamic Network Models"],["dc.type","book"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1513"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Clinical Rheumatology"],["dc.bibliographiccitation.lastpage","1520"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Klemm, Philipp"],["dc.contributor.author","Hudowenz, Ole"],["dc.contributor.author","Asendorf, Thomas"],["dc.contributor.author","Dischereit, Gabriel"],["dc.contributor.author","Müller-Ladner, Ulf"],["dc.contributor.author","Lange, Uwe"],["dc.contributor.author","Tarner, Ingo H."],["dc.date.accessioned","2020-12-10T14:11:09Z"],["dc.date.available","2020-12-10T14:11:09Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s10067-019-04887-6"],["dc.identifier.eissn","1434-9949"],["dc.identifier.issn","0770-3198"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70980"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Evaluation of a special concept of physical therapy in spondyloarthritis: German multimodal rheumatologic complex treatment for spondyloarthritis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","16"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","npj Science of Learning"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Sauce, Bruno"],["dc.contributor.author","Wiedenhoeft, John"],["dc.contributor.author","Judd, Nicholas"],["dc.contributor.author","Klingberg, Torkel"],["dc.date.accessioned","2021-07-05T15:00:30Z"],["dc.date.available","2021-07-05T15:00:30Z"],["dc.date.issued","2021"],["dc.description.abstract","The interplay of genetic and environmental factors behind cognitive development has preoccupied multiple fields of science and sparked heated debates over the decades. Here we tested the hypothesis that developmental genes rely heavily on cognitive challenges—as opposed to natural maturation. Starting with a polygenic score (cogPGS) that previously explained variation in cognitive performance in adults, we estimated its effect in 344 children and adolescents (mean age of 12 years old, ranging from 6 to 25) who showed changes in working memory (WM) in two distinct samples: (1) a developmental sample showing significant WM gains after 2 years of typical, age-related development, and (2) a training sample showing significant, experimentally-induced WM gains after 25 days of an intense WM training. We found that the same genetic factor, cogPGS, significantly explained the amount of WM gain in both samples. And there was no interaction of cogPGS with sample, suggesting that those genetic factors are neutral to whether the WM gains came from development or training. These results represent evidence that cognitive challenges are a central piece in the gene-environment interplay during cognitive development. We believe our study sheds new light on previous findings of interindividual differences in education (rich-get-richer and compensation effects), brain plasticity in children, and the heritability increase of intelligence across the lifespan."],["dc.identifier.doi","10.1038/s41539-021-00096-6"],["dc.identifier.pii","96"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/87840"],["dc.language.iso","en"],["dc.notes.intern","DOI Import DOI-Import GROB-441"],["dc.relation.eissn","2056-7936"],["dc.title","Change by challenge: A common genetic basis behind childhood cognitive development and cognitive training"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","187"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Research Synthesis Methods"],["dc.bibliographiccitation.lastpage","199"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Pieper, Dawid"],["dc.contributor.author","Antoine, Sunya-Lee"],["dc.contributor.author","Morfeld, Jana-Carina"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Eikermann, Michaela"],["dc.date.accessioned","2021-10-27T09:52:42Z"],["dc.date.available","2021-10-27T09:52:42Z"],["dc.date.issued","2014-09"],["dc.description.abstract","Overviews search for reviews rather than for primary studies. They might have the potential to support decision making within a shorter time frame by reducing production time. We aimed to summarize available instructions for authors intending to conduct overviews as well as the currently applied methodology of overviews in international Health Technology Assessment (HTA) agencies."],["dc.identifier.doi","10.1002/jrsm.1107"],["dc.identifier.pmid","26052845"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91410"],["dc.language.iso","en"],["dc.relation.eissn","1759-2887"],["dc.relation.issn","1759-2879"],["dc.title","Methodological approaches in conducting overviews: current state in HTA agencies"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Medical Research Methodology"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Helbach, Jasmin"],["dc.contributor.author","Pieper, Dawid"],["dc.contributor.author","Mathes, Tim"],["dc.contributor.author","Rombey, Tanja"],["dc.contributor.author","Zeeb, Hajo"],["dc.contributor.author","Allers, Katharina"],["dc.contributor.author","Hoffmann, Falk"],["dc.date.accessioned","2022-09-01T09:50:54Z"],["dc.date.available","2022-09-01T09:50:54Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract\n \n Background\n Restrictions in systematic reviews (SRs) can lead to bias and may affect conclusions. Therefore, it is important to report whether and which restrictions were used. This study aims to examine the use of restrictions regarding language, publication period, and study type, as well as the transparency of reporting in SRs of effectiveness.\n \n \n Methods\n A retrospective observational study was conducted with a random sample of 535 SRs of effectiveness indexed in PubMed between 2000 and 2019. The use of restrictions and their reporting were analysed using descriptive statistics.\n \n \n Results\n Of the total 535 SRs included, four out of every ten (41.3%) lacked information on at least one of the three restrictions considered (language, publication period, or study type). Overall, 14.6% of SRs did not provide information on restrictions regarding publication period, 19.1% regarding study type, and 18.3% regarding language. Of all included SRs, language was restricted in 46.4%, and in more than half of the SRs with restricted language (130/248), it was unclear whether the restriction was applied during either the search or the screening process, or both. The restrictions were justified for publication period in 22.2% of the respective SRs (33/149), study type in 6.5% (28/433), and language in 3.2% (8/248). Differences in reporting were found between countries as well as between Cochrane and non-Cochrane reviews.\n \n \n Conclusions\n This study suggests that there is a lack of transparency in reporting on restrictions in SRs. Authors as well as editors and reviewers should be encouraged to improve the reporting and justification of restrictions to increase the transparency of SRs."],["dc.identifier.doi","10.1186/s12874-022-01710-w"],["dc.identifier.pii","1710"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113830"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","1471-2288"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Restrictions and their reporting in systematic reviews of effectiveness: an observational study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Palliative Care"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Kaiser, Ulrich"],["dc.contributor.author","Vehling-Kaiser, Ursula"],["dc.contributor.author","Kück, Fabian"],["dc.contributor.author","Mechie, Nicolae-Catalin"],["dc.contributor.author","Hoffmann, Ana"],["dc.contributor.author","Kaiser, Florian"],["dc.date.accessioned","2021-04-14T08:32:46Z"],["dc.date.available","2021-04-14T08:32:46Z"],["dc.date.issued","2020"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.doi","10.1186/s12904-020-00648-4"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17546"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/84010"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1472-684X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Use of symptom-focused oncological cancer therapies in hospices: a retrospective analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]