Böhrnsen, Florian

[["dc.bibliographiccitation.firstpage","035001"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Biomedical Materials"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Florian, Böhrnsen"],["dc.contributor.author","Michel, Krier"],["dc.contributor.author","Steffi, Grohmann"],["dc.contributor.author","Nicole, Hauptmann"],["dc.contributor.author","Frant, Marion"],["dc.contributor.author","Klaus, Liefeith"],["dc.contributor.author","Henning, Schliephake"],["dc.date.accessioned","2020-12-10T18:15:58Z"],["dc.date.available","2020-12-10T18:15:58Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1088/1748-605X/ab0362"],["dc.identifier.eissn","1748-605X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75008"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","MSC differentiation on two-photon polymerized, stiffness and BMP2 modified biological copolymers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","238"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Cranio-Maxillofacial Surgery"],["dc.bibliographiccitation.lastpage","245"],["dc.bibliographiccitation.volume","49"],["dc.contributor.author","Böhrnsen, Florian"],["dc.contributor.author","Melsheimer, Petra"],["dc.contributor.author","Natorp, Mareike"],["dc.contributor.author","Rolf, Hans"],["dc.contributor.author","Schminke, Boris"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Wolfer, Susanne"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2021-04-14T08:28:56Z"],["dc.date.available","2021-04-14T08:28:56Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1016/j.jcms.2020.03.001"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82745"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","1010-5182"],["dc.title","Cotransplantation of mesenchymal stromal cells and endothelial cells on calcium carbonate and hydroxylapatite scaffolds in vivo"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","668"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Oral Oncology"],["dc.bibliographiccitation.lastpage","673"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Kramer, Franz-Josef"],["dc.contributor.author","Böhrnsen, Florian"],["dc.contributor.author","Moser, Norman"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-06-26T06:55:52Z"],["dc.date.available","2018-06-26T06:55:52Z"],["dc.date.issued","2015"],["dc.description.abstract","The submental island flap has become increasingly popular in the treatment of intraoral defects following tumor ablation. However, there was concern that the elevation of the pedicled flap might interfere with the efficiency of level I-lymph node dissection and decrease the oncologic prognosis of the patients."],["dc.identifier.doi","10.1016/j.oraloncology.2015.03.011"],["dc.identifier.pmid","25962940"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15147"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1879-0593"],["dc.title","The submental island flap for the treatment of intraoral tumor-related defects: No effect on recurrence rates"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1121"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","1128"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Böhrnsen, F."],["dc.contributor.author","Fricke, M."],["dc.contributor.author","Sander, C."],["dc.contributor.author","Leha, A."],["dc.contributor.author","Schliephake, H."],["dc.contributor.author","Kramer, F. J."],["dc.date.accessioned","2018-06-26T08:09:06Z"],["dc.date.available","2018-06-26T08:09:06Z"],["dc.date.issued","2015"],["dc.description.abstract","Cancer progression is influenced by tumor microenvironment and communication of stromal cells and tumor cells. Interactions may enhance epithelial-mesenchymal transition (EMT) of tumor cells through signaling proteins such as Wnt/beta-catenin and matrix metalloproteinases (MMP), as well as loss of cellular integrity, which affects invasion, progression, and metastasis of head and neck squamous cell carcinoma (HNSCC). In this study, we are testing the hypothesis that interactions of human mesenchymal stromal cells (MSCs) with HNSCC might influence the expression of markers of EMT and tumor progression by co-culturing human MSC with the PCI-13 HNSCC line."],["dc.identifier.doi","10.1007/s00784-014-1338-7"],["dc.identifier.pmid","25346374"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15148"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1436-3771"],["dc.title","Interactions of human MSC with head and neck squamous cell carcinoma cell line PCI-13 reduce markers of epithelia-mesenchymal transition"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e175"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","The International Journal of Oral and Maxillofacial Implants"],["dc.bibliographiccitation.lastpage","e182"],["dc.bibliographiccitation.volume","32"],["dc.contributor.author","Böhrnsen, Florian"],["dc.contributor.author","Rublack, Jennifer"],["dc.contributor.author","Aeckerle, Nelia"],["dc.contributor.author","Foerster, Anne"],["dc.contributor.author","Schwenzer, Bernd"],["dc.contributor.author","Reichert, Judith"],["dc.contributor.author","Scharnweber, Dieter"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-06-26T06:41:11Z"],["dc.date.available","2018-06-26T06:41:11Z"],["dc.date.issued","2017"],["dc.description.abstract","Previous in vitro studies have shown that DNA oligonucleotides (ODN) can be successfully used as anchor strands for the binding and retarded release of biologically active recombinant human bone morphogenetic protein 2 (rhBMP-2). The aim of the present study was to test the hypothesis that rhBMP-2 bound to the surface of titanium implants through hybridization with nano-anchored ODN strands is biologically active and can enhance the induction of osteogenic markers in peri-implant bone in vivo."],["dc.fs.pkfprnr","87299"],["dc.identifier.doi","10.11607/jomi.5256"],["dc.identifier.fs","626953"],["dc.identifier.pmid","28212453"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15146"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1942-4434"],["dc.title","Bone Morphogenetic Protein-2 Hybridized with Nano-Anchored Oligonucleotides on Titanium Implants Enhances Osteogenic Differentiation In Vivo"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","731"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of Cranio-Maxillofacial Surgery"],["dc.bibliographiccitation.lastpage","740"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Böhrnsen, Florian"],["dc.contributor.author","Godek, F."],["dc.contributor.author","Kiesel, J."],["dc.contributor.author","Kramer, Franz-Josef"],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-06-25T07:36:02Z"],["dc.date.available","2018-06-25T07:36:02Z"],["dc.date.issued","2017-05"],["dc.description.abstract","TGF-β1 signaling modulates epithelial mesenchymal transitions (EMT) of head and neck squamous cell carcinoma (HNSCC). Bone marrow mesenchymal stromal cells (BMSC) are able to exert a regulating influence on the expression of markers of EMT in HNSCC cells. It was thus the aim of this study to test the hypothesis that TGF-β1 modulates the interactions of tumor transition between BMSCs and HNSCC, affecting the expression of E-cadherin, Vimentin, Snail, Twist, MMP14 and beta-catenin. Furthermore, we analyzed alterations in the AKT-signaling of tumor and stroma cells."],["dc.fs.pkfprnr","43706"],["dc.identifier.doi","10.1016/j.jcms.2017.02.009"],["dc.identifier.fs","626954"],["dc.identifier.pmid","28318921"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15132"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1878-4119"],["dc.title","Influence of TGF-β1 on tumor transition in oral cancer cell and BMSC co-cultures"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","157"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","International Journal of Oral and Maxillofacial Surgery"],["dc.bibliographiccitation.lastpage","165"],["dc.bibliographiccitation.volume","49"],["dc.contributor.author","Böhrnsen, F."],["dc.contributor.author","Holzenburg, J."],["dc.contributor.author","Godek, F."],["dc.contributor.author","Kauffmann, P."],["dc.contributor.author","Moser, N."],["dc.contributor.author","Schliephake, H."],["dc.date.accessioned","2020-12-10T14:24:38Z"],["dc.date.available","2020-12-10T14:24:38Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.ijom.2019.06.001"],["dc.identifier.issn","0901-5027"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72310"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Influence of tumour necrosis factor alpha on epithelial–mesenchymal transition of oral cancer cells in co-culture with mesenchymal stromal cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","223"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","International journal of Oral Science"],["dc.bibliographiccitation.lastpage","230"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Böhrnsen, Florian"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-06-25T06:58:47Z"],["dc.date.available","2018-06-25T06:58:47Z"],["dc.date.issued","2016"],["dc.description.abstract","Sites of implantation with compromised biology may be unable to achieve the required level of angiogenic and osteogenic regeneration. The specific function and contribution of different cell types to the formation of prevascularized, osteogenic networks in co-culture remains unclear. To determine how bone marrow-derived mesenchymal stromal cells (BMSCs) and endothelial cells (ECs) contribute to cellular proangiogenic differentiation, we analysed the differentiation of BMSCs and ECs in standardized monolayer, Transwell and co-cultures. BMSCs were derived from the iliac bone marrow of five patients, characterized and differentiated in standardized monolayers, permeable Transwells and co-cultures with human umbilical vein ECs (HUVECs). The expression levels of CD31, von Willebrand factor, osteonectin (ON) and Runx2 were assessed by quantitative reverse transcriptase polymerase chain reaction. The protein expression of alkaline phosphatase, ON and CD31 was demonstrated via histochemical and immunofluorescence analysis. The results showed that BMSCs and HUVECs were able to retain their lineage-specific osteogenic and angiogenic differentiation in direct and indirect co-cultures. In addition, BMSCs demonstrated a supportive expression of angiogenic function in co-culture, while HUVEC was able to improve the expression of osteogenic marker molecules in BMSCs."],["dc.identifier.doi","10.1038/ijos.2016.39"],["dc.identifier.pmid","27910940"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14234"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15128"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.relation.eissn","2049-3169"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Supportive angiogenic and osteogenic differentiation of mesenchymal stromal cells and endothelial cells in monolayer and co-cultures"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]