Now showing 1 - 8 of 8
  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","87"],["dc.bibliographiccitation.journal","Hearing Research"],["dc.bibliographiccitation.lastpage","99"],["dc.bibliographiccitation.volume","295"],["dc.contributor.author","Golm, Dennis"],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Kroener-Herwig, Birgit"],["dc.date.accessioned","2018-11-07T09:30:12Z"],["dc.date.available","2018-11-07T09:30:12Z"],["dc.date.issued","2013"],["dc.description.abstract","Chronic tinnitus affects approximately 5% of the population. Severe distress due to the phantom noise is experienced by 20% of the tinnitus patients. This distress cannot be predicted by psychoacoustic features of the tinnitus. It is commonly assumed that negative cognitive emotional evaluation of the tinnitus and its expected consequences is a major factor that determines the impact of tinnitus-related distress. Models of tinnitus distress and recently conducted research propose differences in limbic, frontal and parietal processing between highly and low distressed tinnitus patients. An experimental paradigm using verbal material to stimulate cognitive emotional processing of tinnitus-related information was conducted. Age and sex matched highly (n = 16) and low (n = 16) distressed tinnitus patients and healthy controls (n = 16) underwent functional magnetic resonance imaging (fMRI) while sentences with neutral, negative or tinnitus-related content were presented. A random effects group analysis was performed on the basis of the general linear model. Tinnitus patients showed stronger activations to tinnitus-related sentences in comparison to neutral sentences than healthy controls in various limbic/emotion processing areas, such as the anterior cingulate cortex, midcingulate cortex, posterior cingulate cortex, retrosplenial cortex and insula and also in frontal areas. Highly and low distressed tinnitus patients differed in terms of activation of the left middle frontal gyrus. A connectivity analysis and correlational analysis between the predictors of the general linear model of relevant contrasts and tinnitus-related distress further supported the idea of a fronto-parietal-cingulate network, which seems to be more active in highly distressed tinnitus patients. This network may present an aspecific distress network. Based on the findings the left middle frontal gyrus and the right medial frontal gyrus are suggested as target regions for neuromodulatory approaches in the treatment of tinnitus. For future studies we recommend the use of idiosyncratic stimulus material. (C) 2012 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.heares.2012.03.003"],["dc.identifier.isi","000315557100011"],["dc.identifier.pmid","22445697"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31249"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1878-5891"],["dc.relation.issn","0378-5955"],["dc.title","Neural correlates of tinnitus related distress: An fMRI-study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2012Conference Abstract
    [["dc.bibliographiccitation.journal","International Journal of Behavioral Medicine"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Golm, Dennis"],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Kroener-Herwig, Birgit"],["dc.date.accessioned","2018-11-07T09:06:59Z"],["dc.date.available","2018-11-07T09:06:59Z"],["dc.date.issued","2012"],["dc.format.extent","S97"],["dc.identifier.isi","000209816000235"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25681"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.issn","1532-7558"],["dc.relation.issn","1070-5503"],["dc.title","NEURAL CORRELATES OF TINNITUS ANNOYANCE AND ITS REDUCTION AFTER COGNITIVE-BEHAVIORAL TRAINING: RESULTS FROM AN EMOTIONAL STROOP TASK"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","930"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of Pain"],["dc.bibliographiccitation.lastpage","943"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Barke, Antonia"],["dc.contributor.author","Preis, Mira A."],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Baudewig, Juergen"],["dc.contributor.author","Kroener-Herwig, Birgit"],["dc.contributor.author","Dechent, Peter"],["dc.date.accessioned","2018-11-07T10:11:05Z"],["dc.date.available","2018-11-07T10:11:05Z"],["dc.date.issued","2016"],["dc.description.abstract","The fear-avoidance model postulates that in an initial acute phase chronic low back pain (CLBP) patients acquire a fear of movement that results in avoidance of physical activity and contributes to the pain becoming chronic. The current functional magnetic resonance imaging study investigated the neural correlates of imagining back-straining and neutral movements in CLBP patients with high (HFA) and low fear avoidance (LFA) and healthy pain-free participants. Ninety-three persons (62 CLBP patients, 31 healthy controls; age 49.7 +/- 9.2 years) participated. The CLBP patients were divided into an HFA and an LFA group using the Tampa Scale of Kinesiophobia. The participants viewed pictures of back-straining and neutral movements and were instructed to imagine that they themselves were executing the activity shown. When imagining back-straining movements, HFA patients as well as healthy controls showed stronger anterior hippocampus activity than LFA patients. The neural activations of HFA patients did not differ from those of healthy controls. This may indicate that imagining back-straining movements triggered pain-related evaluations in healthy controls and HFA participants, but not in LFA participants. Although heightened pain expectancy in HFA compared with LFA patients fits well with the fear-avoidance model, the difference between healthy controls and LFA patients was unexpected and contrary to the fear-avoidance model. Possibly, negative evaluations of the back-straining movements are common but the LFA patients use some kind of strategy enabling them to react differently to the back-straining events. Perspective: It appears that low fear-avoidant back pain patients use some kind of strategy or underlying mechanism that enables them to react with less fear in the face of potentially painful movements. This warrants further investigation because countering fear and avoidance provide an important advantage with respect to disability. (C) 2016 by the American Pain Society"],["dc.identifier.doi","10.1016/j.jpain.2016.05.005"],["dc.identifier.isi","000381241800007"],["dc.identifier.pmid","27260637"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39978"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Churchill Livingstone"],["dc.relation.issn","1526-5900"],["dc.title","Neural Correlates Differ in High and Low Fear-Avoidant Chronic Low Back Pain Patients When Imagining Back-Straining Movements"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","411"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Pain"],["dc.bibliographiccitation.lastpage","418"],["dc.bibliographiccitation.volume","154"],["dc.contributor.author","Preis, Mira A."],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Kroener-Herwig, Birgit"],["dc.date.accessioned","2018-11-07T09:27:49Z"],["dc.date.available","2018-11-07T09:27:49Z"],["dc.date.issued","2013"],["dc.description.abstract","Neuroimaging studies have revealed partially shared neural substrates for both the actual experience of pain and empathy elicited by the pain of others. We examined whether prior pain exposure increased neural activity in the anterior midcingulate cortex (aMCC) and bilateral anterior insula (AI) as a correlate of empathy for pain. Participants (N = 64: 32 women, 32 men) viewed pictures displaying exposure to pressure pain (pain pictures) and pictures without any cue of pain (neutral pictures). Prior to the experiment, half of the participants were exposed to the same pain stimulus as the one seen in the pain pictures (pain exposure condition); the other half had no such experience (touch exposure condition). A balanced sex ratio was kept, to investigate possible sex differences. In the region-of-interest analyses, participants of the pain exposure condition showed decreased activity in the right AI and the aMCC relative to participants of the touch exposure condition. While in men, no differences were found in relation to their exposure condition, women with pain exposure showed decreased activity in the aMCC and additionally, in bilateral AI. Based on the entire sample, whole brain analyses revealed stronger activation in the retrosplenial cortex, dorsomedial prefrontal cortex, and medial prefrontal cortex in the pain exposure condition. In conclusion, prior pain exposure did not increase, but decreased activity in regions regularly associated with empathy for pain. However, pain experience increased activity in regions associated with memory retrieval, perspective taking, and top-down emotion regulation, which might facilitate empathizing with others. (C) 2012 International Association for the Study of Pain. Published by Elsevier B. V. All rights reserved."],["dc.identifier.doi","10.1016/j.pain.2012.11.014"],["dc.identifier.isi","000315299800015"],["dc.identifier.pmid","23318128"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30628"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0304-3959"],["dc.title","The effects of prior pain experience on neural correlates of empathy for pain: An fMRI study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2012Conference Abstract
    [["dc.bibliographiccitation.firstpage","S240"],["dc.bibliographiccitation.journal","International Journal of Behavioral Medicine"],["dc.bibliographiccitation.lastpage","S241"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Barke, A."],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Kroener-Herwig, Birgit"],["dc.date.accessioned","2018-11-07T09:06:58Z"],["dc.date.available","2018-11-07T09:06:58Z"],["dc.date.issued","2012"],["dc.identifier.isi","000209816000579"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25680"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.issn","1532-7558"],["dc.relation.issn","1070-5503"],["dc.title","CHRONIC LOW BACK PAIN PATIENTS WITH HIGH AND LOW KINESIOPHOBIA IMAGINE PAINFUL AND NEUTRAL MOVEMENTS - FMRI STUDY OF NEURAL CORRELATES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2012Conference Abstract
    [["dc.bibliographiccitation.journal","International Journal of Behavioral Medicine"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Preis, Mira A."],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Kroener-Herwig, Birgit"],["dc.date.accessioned","2018-11-07T09:06:59Z"],["dc.date.available","2018-11-07T09:06:59Z"],["dc.date.issued","2012"],["dc.format.extent","S240"],["dc.identifier.isi","000209816000578"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25686"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.issn","1532-7558"],["dc.relation.issn","1070-5503"],["dc.title","DOES PRIOR PAIN EXPERIENCE MODULATE NEURAL CORRELATES OF EMPATHY FOR PAIN?"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2012Journal Article
    [["dc.bibliographiccitation.firstpage","540"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Pain"],["dc.bibliographiccitation.lastpage","552"],["dc.bibliographiccitation.volume","153"],["dc.contributor.author","Barke, Antonia"],["dc.contributor.author","Baudewig, Juergen"],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Kroener-Herwig, Birgit"],["dc.date.accessioned","2018-11-07T09:13:10Z"],["dc.date.available","2018-11-07T09:13:10Z"],["dc.date.issued","2012"],["dc.description.abstract","The fear-avoidance model postulates that in chronic low back pain (CLBP) a fear of movement is acquired in the acute phase, which leads to subsequent avoidance of physical activity and contributes to the pain syndrome's becoming chronic. In the present event-related functional magnetic resonance imaging (fMRI) study of the neural correlates of the fear of movement, 60 women (30 CLBP patients, 15 healthy controls, and 15 women with spider phobia; mean age 46.8 +/- 9.8 years) participated. The CLBP patients were divided into a high and low fear-avoidant group on the basis of the Tampa Scale of Kinesiophobia. The participants viewed photographs depicting neutral and aversive (back-stressing) movements, generally fear-inducing and neutral pictures from the International Affective Picture System, and pictures of spiders while fMRI data were acquired. It was hypothesized that the high fear-avoidant CLBP patients would show fear-related activations when viewing the aversive movements and that they would differ from CLBP patients with low fear-avoidance and controls in this regard. No such activations were found for high or low fear-avoidant CLBP patients. The random-effects analysis showed no differences between high and low fear-avoidant CLBP patients or high fear-avoidant CLBP patients and controls. Normal fear-related activations were present in the high fear-avoidant CLBP patients for the generally fear-inducing pictures, demonstrating the validity of the stimulation paradigm and a generally unimpaired fear processing of the high fear-avoidant CLBP patients. Our findings do not support the fear component of the fear avoidance model. (C) 2011 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.pain.2011.11.012"],["dc.identifier.isi","000300616600010"],["dc.identifier.pmid","22230805"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27111"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0304-3959"],["dc.title","Neural correlates of fear of movement in high and low fear-avoidant chronic low back pain patients: An event-related fMRI study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.artnumber","e0137056"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Preis, Mira A."],["dc.contributor.author","Kroener-Herwig, Birgit"],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Barke, Antonia"],["dc.date.accessioned","2018-11-07T09:53:06Z"],["dc.date.available","2018-11-07T09:53:06Z"],["dc.date.issued","2015"],["dc.description.abstract","Background Neuroimaging studies have demonstrated that the actual experience of pain and the perception of another person in pain share common neural substrates, including the bilateral anterior insular cortex and the anterior midcingulate cortex. As many fMRI studies include the exposure of participants to repeated, similar stimuli, we examined whether empathic neural responses were affected by habituation and whether the participants' prior pain experience influenced these habituation effects. Method In 128 trials (four runs), 62 participants (31 women, 23.0 +/- 4.2 years) were shown pictures of hands exposed to painful pressure (pain pictures) and unexposed (neutral pictures). After each trial, the participants rated the pain of the model. Prior to the experiment, participants were either exposed to the same pain stimulus (pain exposure group) or not (touch exposure group). In order to assess possible habituation effects, linear changes in the strength of the BOLD response to the pain pictures (relative to the neutral pictures) and in the ratings of the model's pain were evaluated across the four runs. Results Although the ratings of the model's pain remained constant over time, we found neural habituation in the bilateral anterior/midinsular cortex, the posterior midcingulate extending to dorsal posterior cingulate cortex, the supplementary motor area, the cerebellum, the right inferior parietal lobule, and the left superior frontal gyrus, stretching to the pregenual anterior cingulate cortex. The participant's prior pain experience did neither affect their ratings of the model's pain nor their maintenance of BOLD activity in areas associated with empathy. Interestingly, participants with high trait personal distress and fantasy tended to show less habituation in the anterior insula. Conclusion Neural structures showed a decrease of the BOLD signal, indicating habituation over the course of 45 minutes. This can be interpreted as a neuronal mechanism responding to the repeated exposure to pain depictions, which may be regarded as functional in a range of contexts."],["dc.identifier.doi","10.1371/journal.pone.0137056"],["dc.identifier.isi","000360299100200"],["dc.identifier.pmid","26317858"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12086"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36260"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Neural Correlates of Empathy with Pain Show Habituation Effects. An fMRI Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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