Haubrock, Martin

[["dc.bibliographiccitation.firstpage","D343"],["dc.bibliographiccitation.issue","D1"],["dc.bibliographiccitation.journal","Nucleic Acids Research"],["dc.bibliographiccitation.lastpage","D347"],["dc.bibliographiccitation.volume","46"],["dc.contributor.author","Wingender, Edgar"],["dc.contributor.author","Schoeps, Torsten"],["dc.contributor.author","Haubrock, Martin"],["dc.contributor.author","Krull, Mathias"],["dc.contributor.author","Dönitz, Jürgen"],["dc.date.accessioned","2019-07-09T11:45:00Z"],["dc.date.available","2019-07-09T11:45:00Z"],["dc.date.issued","2018"],["dc.description.abstract","TFClass is a resource that classifies eukaryotic transcription factors (TFs) according to their DNA-binding domains (DBDs), available online at http://tfclass.bioinf.med.uni-goettingen.de. The classification scheme of TFClass was originally derived for human TFs and is expanded here to the whole taxonomic class of mammalia. Combining information from different resources, checking manually the retrieved mammalian TFs sequences and applying extensive phylogenetic analyses, >39 000 TFs from up to 41 mammalian species were assigned to the Superclasses, Classes, Families and Subfamilies of TFClass. As a result, TFClass now provides the corresponding sequence collection in FASTA format, sequence logos and phylogenetic trees at different classification levels, predicted TF binding sites for human, mouse, dog and cow genomes as well as links to several external databases. In particular, all those TFs that are also documented in the TRANSFAC® database (FACTOR table) have been linked and can be freely accessed. TRANSFAC® FACTOR can also be queried through an own search interface."],["dc.identifier.doi","10.1093/nar/gkx987"],["dc.identifier.pmid","29087517"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14998"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59137"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1362-4962"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","TFClass: expanding the classification of human transcription factors to their mammalian orthologs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","374"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Nucleic Acids Research"],["dc.bibliographiccitation.lastpage","378"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Matys, V."],["dc.contributor.author","Haubrock, M."],["dc.contributor.author","Wingender, E."],["dc.date.accessioned","2022-06-08T07:59:10Z"],["dc.date.available","2022-06-08T07:59:10Z"],["dc.date.issued","2003"],["dc.description.abstract","The TRANSFAC® database on eukaryotic transcriptional regulation, comprising data on transcription factors, their target genes and regulatory binding sites, has been extended and further developed, both in number of entries and in the scope and structure of the collected data. Structured fields for expression patterns have been introduced for transcription factors from human and mouse, using the CYTOMER® database on anatomical structures and developmental stages. The functionality of MatchTM, a tool for matrix-based search of transcription factor binding sites, has been enhanced. For instance, the program now comes along with a number of tissue-(or state-)specific profiles and new profiles can be created and modified with MatchTM Profiler. The GENE table was extended and gained in importance, containing amongst others links to LocusLink, RefSeq and OMIM now. Further, (direct) links between factor and target gene on one hand and between gene and encoded factor on the other hand were introduced. The TRANSFAC® public release is available at http://www.gene-regulation.com. For yeast an additional release including the latest data was made available separately as TRANSFAC® Saccharomyces Module (TSM) at http://transfac.gbf.de. For CYTOMER® free download versions are available at http://www.biobase.de:8080/index.html."],["dc.identifier.doi","10.1093/nar/gkg108"],["dc.identifier.fs","12171"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/4111"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/110656"],["dc.notes.intern","DOI-Import GROB-575"],["dc.relation.eissn","1362-4962"],["dc.relation.issn","1362-4962"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","TRANSFAC(R): transcriptional regulation, from patterns to profiles"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]