Ackermann, Lutz

[["dc.bibliographiccitation.artnumber","15430"],["dc.bibliographiccitation.journal","Nature Communications"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Li, Jie"],["dc.contributor.author","Korvorapun, Korkit"],["dc.contributor.author","De Sarkar, Suman"],["dc.contributor.author","Rogge, Torben"],["dc.contributor.author","Burns, David J."],["dc.contributor.author","Warratz, Svenja"],["dc.contributor.author","Ackermann, Lutz"],["dc.date.accessioned","2018-11-07T10:22:45Z"],["dc.date.available","2018-11-07T10:22:45Z"],["dc.date.issued","2017"],["dc.description.abstract","The full control of positional selectivity is of prime importance in C-H activation technology. Chelation assistance served as the stimulus for the development of a plethora of ortho-selective arene functionalizations. In sharp contrast, meta-selective C-H functionalizations continue to be scarce, with all ruthenium-catalysed transformations currently requiring difficult to remove or modify nitrogen-containing heterocycles. Herein, we describe a unifying concept to access a wealth of meta-decorated arenes by a unique arene ligand effect in proximity-induced ruthenium(II) C-H activation catalysis. The transformative nature of our strategy is mirrored by providing a step-economical entry to a range of meta-substituted arenes, including ketones, acids, amines and phenols-key structural motifs in crop protection, material sciences, medicinal chemistry and pharmaceutical industries."],["dc.identifier.doi","10.1038/ncomms15430"],["dc.identifier.isi","000402961800001"],["dc.identifier.pmid","28598411"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14905"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42331"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Nature Publishing Group"],["dc.relation.issn","2041-1723"],["dc.rights.access","openAccess"],["dc.subject.ddc","540"],["dc.title","Ruthenium(II)-catalysed remote C-H alkylations as a versatile platform to meta-decorated arenes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","429"],["dc.bibliographiccitation.issue","04"],["dc.bibliographiccitation.journal","Synlett"],["dc.bibliographiccitation.lastpage","432"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Ghorai, Debasish"],["dc.contributor.author","Loup, Joachim"],["dc.contributor.author","Zanoni, Giuseppe"],["dc.contributor.author","Ackermann, Lutz"],["dc.date.accessioned","2019-07-09T11:50:31Z"],["dc.date.available","2019-07-09T11:50:31Z"],["dc.date.issued","2019"],["dc.description.abstract","Air- and moisture-stable secondary phosphine oxides (SPOs) enabled nickel-catalyzed Kumada–Corriu cross-couplings of various arylmethyl ethers at room temperature by challenging C–O activation."],["dc.identifier.doi","10.1055/s-0037-1611663"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15952"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59785"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/307535/EU//CATCHFUN"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.subject.ddc","540"],["dc.title","Air-Stable Secondary Phosphine Oxides for Nickel-Catalyzed Cross-Couplings of Aryl Ethers by C–O Activation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","ChemCatChem"],["dc.bibliographiccitation.lastpage","6"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Müller, Valentin"],["dc.contributor.author","Weck, Remo"],["dc.contributor.author","Derdau, Volker"],["dc.contributor.author","Ackermann, Lutz"],["dc.date.accessioned","2019-12-19T10:05:50Z"],["dc.date.accessioned","2021-10-27T13:12:50Z"],["dc.date.available","2019-12-19T10:05:50Z"],["dc.date.available","2021-10-27T13:12:50Z"],["dc.date.issued","2019"],["dc.description.abstract","Well-defined ruthenium(II) biscarboxylate complexes enabled selective ortho-deuteration with weakly-coordinating, synthetically useful carboxylic acid with outstanding levels of isotopic labeling. The robust nature of the catalytic system was reflected by a broad functional group tolerance in an operationallysimple manner, allowing the isotope labeling of challenging pharmaceuticals and bioactive heterocyclic motifs. The synthetic power of our method was highlighted by the selective tritium-labeling of repaglinide, an antidiabetic drug, providing access to defined tritium labeled therapeutics."],["dc.identifier.doi","10.1002/cctc.201902051"],["dc.identifier.eissn","1867-3899"],["dc.identifier.issn","1867-3880"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17034"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91726"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.eissn","1867-3899"],["dc.relation.issn","1867-3899"],["dc.relation.issn","1867-3880"],["dc.relation.orgunit","Fakultät für Chemie"],["dc.rights","CC BY 4.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject","C-H activation; hydrogen isotope exchange; ruthenium; pharmaceutical drugs; tritium"],["dc.subject.ddc","540"],["dc.title","Ruthenium(II)‐Catalyzed Hydrogen Isotope Exchange of Pharmaceutical Drugs by C−H Deuteration and C−H Tritiation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]