Hinrichs, Rena

[["dc.bibliographiccitation.firstpage","88"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Inorganic Biochemistry"],["dc.bibliographiccitation.lastpage","96"],["dc.bibliographiccitation.volume","100"],["dc.contributor.author","Sethmann, I."],["dc.contributor.author","Hinrichs, R."],["dc.contributor.author","Wöheide, G."],["dc.contributor.author","Putnis, A."],["dc.date.accessioned","2018-11-07T10:36:37Z"],["dc.date.available","2018-11-07T10:36:37Z"],["dc.date.issued","2006"],["dc.description.abstract","Spicules of calcareous sponges are elaborately shaped skeletal elements that nonetheless show characteristics of calcite single-crystals. Our atomic force microscopic and transmission electron microscopic investigation of the triradiate spicules of the sponge Pericharax heteroraphis reveals a nano-cluster structure with mostly well-aligned small crystal domains and pockets with accumulated domain mis-alignments. Combined high-resolution and energy-filtering transmission electron microscopy revealed carbon enrichments located in between crystal domain boundaries, which strongly suggests an intercalated network-like proteinaceous organic matrix. This matrix is proposed to be involved in the nano-clustered calcite precipitation via a transient phase that may enable a 'brick-by-brick' formation of composite and yet single-crystalline spicules with elaborate morphologies. This composite cluster structure reduces the brittleness of the material by dissipating strain energy and deflecting crack propagation from the calcite cleavage planes, but the lattice symmetry and anisotropic growth properties of calcite still play a major role in the morphogenesis of these unusual calcite single-crystals. Our structural, crystallographic, textural, and chemical analysis of sponge spicules corroborates the view that nano-clustered crystal growth, induced by organic matrices, is a basic characteristic of biomineralisation that enables the production of composite materials with elaborate morphologies. (C) 2005 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.jinorgbio.2005.10.005"],["dc.identifier.isi","000234770200011"],["dc.identifier.pmid","16321444"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45368"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","Najko"],["dc.relation.issn","0162-0134"],["dc.title","Nano-cluster composite structure of calcitic sponge spicules - A case study of basic characteristics of biominerals"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Investigative Dermatology"],["dc.bibliographiccitation.volume","123"],["dc.contributor.author","Wiesend, Christiane L."],["dc.contributor.author","Grosber, M."],["dc.contributor.author","Schlingmann, J."],["dc.contributor.author","Blaschke, S."],["dc.contributor.author","Vetter, R."],["dc.contributor.author","Hinrichs, R."],["dc.contributor.author","Weiss, J. M."],["dc.contributor.author","Mockenhaupt, Maja"],["dc.date.accessioned","2018-11-07T10:46:51Z"],["dc.date.available","2018-11-07T10:46:51Z"],["dc.date.issued","2004"],["dc.identifier.isi","000222483400114"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47837"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing Inc"],["dc.publisher.place","Malden"],["dc.relation.conference","34th Annual Meeting of the European-Society-for-Dermatological-Research"],["dc.relation.eventlocation","Vienna, AUSTRIA"],["dc.relation.issn","0022-202X"],["dc.title","Multiforme-like adverse skin reactions in association with the use of Bextra (R) (valdecoxib)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1185"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Rheumatology"],["dc.bibliographiccitation.lastpage","1192"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Hunzelmann, Nicolas"],["dc.contributor.author","Genth, Ekkehard"],["dc.contributor.author","Krieg, Thomas"],["dc.contributor.author","Lehmacher, W."],["dc.contributor.author","Melchers, Inga"],["dc.contributor.author","Meurer, Michael"],["dc.contributor.author","Moinzadeh, Pia"],["dc.contributor.author","Mueller-Ladner, Ulf"],["dc.contributor.author","Pfeiffer, C."],["dc.contributor.author","Riemekasten, Gabriela"],["dc.contributor.author","Schulze-Lohoff, Eckhard"],["dc.contributor.author","Sunderkoetter, Cord"],["dc.contributor.author","Weber, M."],["dc.contributor.author","Worm, Margitta"],["dc.contributor.author","Klaus, Petra"],["dc.contributor.author","Rubbert, A."],["dc.contributor.author","Steinbrink, Kerstin"],["dc.contributor.author","Grundt, B."],["dc.contributor.author","Hein, Rebecca"],["dc.contributor.author","Scharffetter-Kochanek, Karin"],["dc.contributor.author","Hinrichs, R."],["dc.contributor.author","Walker, K."],["dc.contributor.author","Szeimies, R.-M."],["dc.contributor.author","Karrer, Sigrid"],["dc.contributor.author","Mueller, A."],["dc.contributor.author","Seitz, C."],["dc.contributor.author","Schmidt, E."],["dc.contributor.author","Lehmann, Percy"],["dc.contributor.author","Foeldvari, Ivan"],["dc.contributor.author","Reichenberger, F."],["dc.contributor.author","Gross, W. L."],["dc.contributor.author","Kuhn, A."],["dc.contributor.author","Haust, Merle"],["dc.contributor.author","Reich, Kristian"],["dc.contributor.author","Boehm, M."],["dc.contributor.author","Saar, P."],["dc.contributor.author","Fierlbeck, Gerhard"],["dc.contributor.author","Koetter, Ina"],["dc.contributor.author","Lorenz, H.-M."],["dc.contributor.author","Blank, Norbert"],["dc.contributor.author","Graefenstein, K."],["dc.contributor.author","Juche, Aaron"],["dc.contributor.author","Aberer, Elisabeth"],["dc.contributor.author","Bali, G."],["dc.contributor.author","Fiehn, Christoph"],["dc.contributor.author","Stadler, R."],["dc.contributor.author","Bartels, V."],["dc.date.accessioned","2018-11-07T11:12:44Z"],["dc.date.available","2018-11-07T11:12:44Z"],["dc.date.issued","2008"],["dc.description.abstract","Objective. Systemic sclerosis (SSc) is a rare, heterogeneous disease, which affects different organs and therefore requires interdisciplinary diagnostic and therapeutic management. To improve the detection and follow-up of patients presenting with different disease manifestations, an interdisciplinary registry was founded with contributions from different subspecialties involved in the care of patients with SSc. Methods. A questionnaire was developed to collect a core set of clinical data to determine the current disease status. Patients were grouped into five descriptive disease subsets, i.e. lcSSc, dcSSc, SSc sine scleroderma, overlap-syndrome and UCTD with scleroderma features. Results. Of the 1483 patients, 45.5 of patients had lcSSc and 32.7 dcSSc. Overlap syndrome was diagnosed in 10.9 of patients, while 8.8 had an undifferentiated form. SSc sine scleroderma was present in 1.5 of patients. Organ involvement was markedly different between subsets; pulmonary fibrosis for instance was significantly more frequent in dcSSc (56.1) than in overlap syndrome (30.6) or lcSSc (20.8). Pulmonary hypertension was more common in dcSSc (18.5) compared with lcSSc (14.9), overlap syndrome (8.2) and undifferentiated disease (4.1). Musculoskeletal involvement was typical for overlap syndromes (67.6). A family history of rheumatic disease was reported in 17.2 of patients and was associated with early disease onset (P < 0.005). Conclusion. In this nationwide register, a descriptive classification of patients with disease manifestations characteristic of SSc in five groups allows to include a broader spectrum of patients with features of SSc."],["dc.identifier.doi","10.1093/rheumatology/ken179"],["dc.identifier.isi","000257787200014"],["dc.identifier.pmid","18515867"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53733"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1462-0324"],["dc.title","The registry of the German Network for Systemic Scleroderma: frequency of disease subsets and patterns of organ involvement"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1083"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Analytical Atomic Spectrometry"],["dc.bibliographiccitation.lastpage","1087"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Kabatas, Selda"],["dc.contributor.author","Agüi-Gonzalez, Paola"],["dc.contributor.author","Hinrichs, Rena"],["dc.contributor.author","Jähne, Sebastian"],["dc.contributor.author","Opazo, Felipe"],["dc.contributor.author","Diederichsen, Ulf"],["dc.contributor.author","Rizzoli, Silvio O."],["dc.contributor.author","Phan, Nhu T. N."],["dc.date.accessioned","2020-12-10T18:11:29Z"],["dc.date.available","2020-12-10T18:11:29Z"],["dc.date.issued","2019"],["dc.description.abstract","Molecular imaging of targeted large biomolecules has been restricted in SIMS due to the limited number of probes containing SIMSdetectable isotopes.We introduce here new 19F-containingmolecules that can be conjugated in a site-specificmanner to nanobodies able to recognize fluorescent proteins (FPs) or mouse immunoglobulins (Igs). In this work, we demonstrate that it is possible to use the 19F-nanobodies to reveal the location of several cellular proteins previously tagged with FPs or Igs. This enables specific bio-imaging in SIMS for a vast repertoire of biomolecules, offering new opportunities to study specific structural and functional molecular interactions in biological specimens."],["dc.identifier.doi","10.1039/C9JA00117D"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16452"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74028"],["dc.identifier.url","https://sfb1286.uni-goettingen.de/literature/publications/24"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.notes.intern","In goescholar not merged with http://resolver.sub.uni-goettingen.de/purl?gs-1/16278 but duplicate"],["dc.relation","SFB 1286: Quantitative Synaptologie"],["dc.relation","SFB 1286 | B01: Der Verteilung struktureller Lipide in synaptischen Membranen"],["dc.relation.eissn","1364-5544"],["dc.relation.issn","0267-9477"],["dc.relation.issn","1364-5544"],["dc.relation.workinggroup","RG Phan"],["dc.relation.workinggroup","RG Rizzoli (Quantitative Synaptology in Space and Time)"],["dc.rights","CC BY 3.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.subject.ddc","610"],["dc.title","Fluorinated nanobodies for targeted molecular imaging of biological samples using nanoscale secondary ion mass spectrometry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]