Horn, Sebastian

[["dc.bibliographiccitation.artnumber","8940"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Dieks, Jana-K."],["dc.contributor.author","Jünemann, Laura"],["dc.contributor.author","Hensel, Kai O."],["dc.contributor.author","Bergmann, Charlotte"],["dc.contributor.author","Schmidt, Stefan"],["dc.contributor.author","Quast, Anja"],["dc.contributor.author","Horn, Sebastian"],["dc.contributor.author","Sigler, Matthias"],["dc.contributor.author","Meyer-Marcotty, Philipp"],["dc.contributor.author","Santander, Petra"],["dc.date.accessioned","2022-06-01T09:39:11Z"],["dc.date.available","2022-06-01T09:39:11Z"],["dc.date.issued","2022"],["dc.description.abstract","Head development is a surrogate for brain development in infants and is related to neurocognitive outcome. There is only limited knowledge on early extra-uterine head shape and size assessment in very preterm infants. Here, 26 very preterm infants with a mean gestational age of 29.1 ± 2.2 weeks and a mean birth weight of 1273.8 ± 427.7 g underwent serial stereophotogrammetric 3D head imaging in weekly intervals from birth to term-equivalent age. The main outcome was the longitudinal assessment of the ‘physiological’ preterm head development with cephalometric size (head circumference, cranial volume) and shape parameters (cranial index, cranial vault asymmetry index) according to chronological and postmenstrual age (PMA). Potential clinical risk factors for the development of an abnormal low cranial index (dolichocephaly) were analysed. In serial measurements of 26 infants, the estimated head volume (95% confidence interval) increased from 244 (226–263) cm 3 at 28 weeks PMA to 705 (688–721) cm 3 at 40 weeks PMA. Moderate or severe dolichocephaly occurred in 21/26 infants (80.8%). Cranial index decreased over time (72.4%; 70.7–74 95% confidence interval). Brachycephaly and plagiocephaly were uncommon. No risk factors for severe dolichocephaly were identified. Our study shows that early detection of head shape and size anomalies utilizing 3D stereophotogrammetry is feasible and safe even in very preterm infants < 1500 g and/or < 32 weeks. 3D stereophotogrammetry could be used for timely identification of infants at risk for head shape anomalies. No specific risk factors for head shape anomalies were identified, especially not mode and duration of respiratory support."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.1038/s41598-022-12887-x"],["dc.identifier.pii","12887"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108408"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","2045-2322"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Stereophotogrammetry can feasibly assess ‘physiological’ longitudinal three-dimensional head development of very preterm infants from birth to term"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","21155"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Santander, Petra"],["dc.contributor.author","Quast, Anja"],["dc.contributor.author","Hubbert, Johanna"],["dc.contributor.author","Juenemann, Laura"],["dc.contributor.author","Horn, Sebastian"],["dc.contributor.author","Hensel, Kai O."],["dc.contributor.author","Meyer-Marcotty, Philipp"],["dc.contributor.author","Dieks, Jana-Katharina"],["dc.date.accessioned","2021-12-01T09:23:10Z"],["dc.date.available","2021-12-01T09:23:10Z"],["dc.date.issued","2021"],["dc.description.abstract","The development of head shape and volume may reflect neurodevelopmental outcome and therefore is of paramount importance in neonatal care. Here, we compare head morphology in 25 very preterm infants with a birth weight of below 1500 g and / or a gestational age (GA) before 32 completed weeks to 25 term infants with a GA of 37–42 weeks at term equivalent age (TEA) and identify possible risk factors for non-synostotic head shape deformities. For three-dimensional head assessments, a portable stereophotogrammetric device was used. The most common and distinct head shape deformity in preterm infants was dolichocephaly. Severity of dolichocephaly correlated with GA and body weight at TEA but not with other factors such as neonatal morbidity, sex or total duration of respiratory support. Head circumference (HC) and cranial volume (CV) were not significantly different between the preterm and term infant group. Digitally measured HC and the CV significantly correlated even in infants with head shape deformities. Our study shows that stereophotogrammetric head assessment is feasible in all preterm and term infants and provides valuable information on volumetry and comprehensive head shape characteristics. In a small sample of preterm infants, body weight at TEA was identified as a specific risk factor for the development of dolichocephaly."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.1038/s41598-021-00680-1"],["dc.identifier.pii","680"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/94581"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-478"],["dc.relation.eissn","2045-2322"],["dc.rights","CC BY 4.0"],["dc.title","Stereophotogrammetric head shape assessment in neonates is feasible and can identify distinct differences between term-born and very preterm infants at term equivalent age"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]