Mössner, Rotraut

[["dc.bibliographiccitation.firstpage","6232S"],["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","Clinical Cancer Research"],["dc.bibliographiccitation.lastpage","6233S"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Mossner, Rotraut"],["dc.contributor.author","Schulz, U."],["dc.contributor.author","Kuger, U."],["dc.contributor.author","Middel, Peter"],["dc.contributor.author","Fuzesi, Laszlo"],["dc.contributor.author","Neumann, C."],["dc.contributor.author","Reich, Kristian"],["dc.date.accessioned","2018-11-07T10:34:17Z"],["dc.date.available","2018-11-07T10:34:17Z"],["dc.date.issued","2003"],["dc.identifier.isi","000187467300668"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44829"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Cancer Research"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics"],["dc.relation.eventlocation","BOSTON, MASSACHUSETTS"],["dc.relation.issn","1078-0432"],["dc.title","Role of peroxisome proliferator-activated receptor (PPAR) gamma in the control of melanoma cell growth."],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Mossner, Rotraut"],["dc.contributor.author","Anders, N."],["dc.contributor.author","Konig, I. R."],["dc.contributor.author","Kruger, Ullrich"],["dc.contributor.author","Schmidt, D."],["dc.contributor.author","Berking, Carola"],["dc.contributor.author","Ziegler, Andreas"],["dc.contributor.author","Brockmoeller, Juergen"],["dc.contributor.author","Volkenandt, Matthias"],["dc.contributor.author","Kaiser, R."],["dc.contributor.author","Westphal, G."],["dc.contributor.author","Reich, Kristian"],["dc.date.accessioned","2018-11-07T10:12:01Z"],["dc.date.available","2018-11-07T10:12:01Z"],["dc.date.issued","2006"],["dc.format.extent","198"],["dc.identifier.isi","000235370600041"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40158"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.publisher.place","Oxford"],["dc.relation.conference","33rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF)"],["dc.relation.eventlocation","Aachen, GERMANY"],["dc.relation.issn","0906-6705"],["dc.title","Variations of the MC1R and the GSTM1 and T1 genes in cutaneous malignant melanoma"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","202"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","204"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Seitz, Cornelia S."],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Mößner, Rotraut"],["dc.date.accessioned","2020-12-10T18:27:17Z"],["dc.date.available","2020-12-10T18:27:17Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1111/ddg.13414"],["dc.identifier.issn","1610-0379"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76296"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Creeping eruption and eosinophilic folliculitis: Atypical cutaneous larva migrans"],["dc.title.alternative","Correspondence"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","39"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Clinical & Experimental Immunology"],["dc.bibliographiccitation.lastpage","44"],["dc.bibliographiccitation.volume","142"],["dc.contributor.author","Hofstetter, Harald H."],["dc.contributor.author","Mossner, Rotraut"],["dc.contributor.author","Lesch, K. P."],["dc.contributor.author","Linker, Ralf Andreas"],["dc.contributor.author","Toyka, Klaus V."],["dc.contributor.author","Gold, Ralf"],["dc.date.accessioned","2018-11-07T10:55:12Z"],["dc.date.available","2018-11-07T10:55:12Z"],["dc.date.issued","2005"],["dc.description.abstract","Serotonin (5-hydroxytryptamine, 5-HT) is one of the most extensively studied neurotransmitters of the central nervous system. It also has been identified in constituents of the immune system. Therefore serotonin has been suggested to serve as a mediator of bidirectional interactions between the nervous system and the immune system. We investigated this interaction in experimental autoimmune encephalomyelitis (EAE), a well-defined animal model of autoimmune disease of the central nervous system (CNS) mimicking features of the human disease multiple sclerosis. EAE was induced by immunization with the autoantigens myelin basic protein (MBP) or the immunodominant peptide of myelin oligodendrocyte glycoprotein (MOG) spanning amino acids 35-55 (MOGp 35-55). We studied EAE in knockout (KO) mice lacking the 5-HT transporter (5-HTT) on a C57.BL/6 background, in comparison with wild-type C57.BL/6 animals. After immunization with MOGp 35-55, or with rat MBP, the disease courses of the 5-HTT knockout mice were attenuated as compared to wildtype control mice. This difference was more pronounced in female animals. To dissect potential immune mechanisms underlying this phenomenon, histological studies of the CNS and cytokine measurements in mononuclear cells from the spleens of 5-HTT KO mice and wild-type controls were performed. We found a reduction of the inflammatory infiltrate in the CNS and of the neuroantigen-specific production of IFN-gamma in splenocytes, again accompanied by a gender difference. These findings suggest a potential role of extracellular 5-HT homeostasis in the fine-tuning of neuroantigen-specific immune responses."],["dc.identifier.doi","10.1111/j.1365-2249.2005.02901.X"],["dc.identifier.isi","000231824900005"],["dc.identifier.pmid","16178854"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49732"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0009-9104"],["dc.title","Absence of reuptake of serotonin influences susceptibility to clinical autoimmune disease and neuroantigen-specific interferon-gamma production in mouse EAE"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Clinical Infectious Diseases"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Moessner, Rotraut"],["dc.contributor.author","Diering, Nina"],["dc.contributor.author","Bader, Oliver"],["dc.contributor.author","Forkel, Susann"],["dc.contributor.author","Overbeck, Tobias R."],["dc.contributor.author","Gross, Uwe"],["dc.contributor.author","Grimbacher, Bodo"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Buhl, Timo"],["dc.date.accessioned","2018-11-07T10:16:10Z"],["dc.date.available","2018-11-07T10:16:10Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1093/cid/ciw020"],["dc.identifier.isi","000374248700026"],["dc.identifier.pmid","26787170"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40985"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.relation.issn","1537-6591"],["dc.relation.issn","1058-4838"],["dc.title","Ruxolitinib Induces Interleukin 17 and Ameliorates Chronic Mucocutaneous Candidiasis Caused by STAT1 Gain-of-Function Mutation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","753"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","771"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Reich, Kristian"],["dc.contributor.author","Augustin, Matthias"],["dc.contributor.author","Gerdes, Sascha"],["dc.contributor.author","Ghoreschi, Kamran"],["dc.contributor.author","Kokolakis, Georgios"],["dc.contributor.author","Mößner, Rotraut"],["dc.contributor.author","Mrowietz, Ulrich"],["dc.contributor.author","Navarini, Alexander A."],["dc.contributor.author","Pinter, Andreas"],["dc.contributor.author","Schäkel, Knut"],["dc.contributor.author","Wilsmann‐Theis, Dagmar"],["dc.date.accessioned","2022-07-01T07:35:12Z"],["dc.date.available","2022-07-01T07:35:12Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1111/ddg.14764"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112108"],["dc.language.iso","de"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.eissn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.rights.uri","http://creativecommons.org/licenses/by-nc-nd/4.0/"],["dc.title","Generalized pustular psoriasis: overview of the status quo and results of a panel discussion"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","576"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Investigative Dermatology"],["dc.bibliographiccitation.lastpage","582"],["dc.bibliographiccitation.volume","119"],["dc.contributor.author","Mossner, Rotraut"],["dc.contributor.author","Schulz, U."],["dc.contributor.author","Kruger, Ullrich"],["dc.contributor.author","Middel, Peter"],["dc.contributor.author","Schinner, S."],["dc.contributor.author","Fuzesi, Laszlo"],["dc.contributor.author","Neumann, C."],["dc.contributor.author","Reich, Kristian"],["dc.date.accessioned","2018-11-07T10:06:19Z"],["dc.date.available","2018-11-07T10:06:19Z"],["dc.date.issued","2002"],["dc.description.abstract","Peroxisome proliferator-activated receptor gamma is a member of the nuclear receptor superfamily involved in adipocyte differentiation and glucose homeostasis. There is evidence that peroxisome proliferator-activated receptor gamma may also act as a tumor suppressor. Here, we demonstrate expression of peroxisome proliferator-activated receptor gamma in benign melanocytic naevi, different variants of primary cutaneous melanomas, and melanoma metastases. Peroxisome proliferator-activated receptor gamma protein and peroxisome proliferator-activated receptor gamma1 mRNA were also detected in human melanoma cell lines. The peroxisome proliferator-activated receptor gamma specific agonists 15-deoxy-Delta(12,14)-prostaglandin J(2), troglitazone, and rosiglitazone dose-dependently inhibited cell proliferation in four melanoma cell lines, whereas a specific agonist of peroxisome proliferator-activated receptor alpha had no such effect. At a concentration of 50 muM rosiglitazone, the most potent peroxisome proliferator-activated receptor gamma agonist tested suppressed cell growth by approximately 90%. Apoptosis could be induced in melanoma cell lines by incubation with tumor-necrosis-factor-related apoptosis-inducing ligand. In contrast, the growth inhibitory effect of peroxisome proliferator-activated receptor gamma activation was independent of apoptosis and seemed to occur primarily through induction of cell cycle arrest. Our data indicate that melanoma cell growth may be modulated through peroxisome proliferator-activated receptor gamma."],["dc.identifier.doi","10.1046/j.1523-1747.2002.01861.x"],["dc.identifier.isi","000177951400006"],["dc.identifier.pmid","12230498"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39070"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing Inc"],["dc.relation.issn","0022-202X"],["dc.title","Agonists of peroxisome proliferator-activated receptor gamma inhibit cell growth in malignant melanoma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","643"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","645"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Schmid, Emilia"],["dc.contributor.author","Mohr, Johannes"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Mössner, Rotraut"],["dc.date.accessioned","2021-06-01T10:47:13Z"],["dc.date.available","2021-06-01T10:47:13Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1111/ddg.13857"],["dc.identifier.eissn","1610-0387"],["dc.identifier.issn","1610-0379"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85525"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Two cases of acrodermatitis continua suppurativa (Hallopeau's disease) treated with IL‐17A inhibitors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2149"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of Investigative Dermatology"],["dc.bibliographiccitation.lastpage","2158.e10"],["dc.bibliographiccitation.volume","142"],["dc.contributor.author","Haskamp, Stefan"],["dc.contributor.author","Frey, Benjamin"],["dc.contributor.author","Becker, Ina"],["dc.contributor.author","Schulz-Kuhnt, Anja"],["dc.contributor.author","Atreya, Imke"],["dc.contributor.author","Berking, Carola"],["dc.contributor.author","Pauli, David"],["dc.contributor.author","Ekici, Arif B."],["dc.contributor.author","Berges, Johannes"],["dc.contributor.author","Mößner, Rotraut"],["dc.contributor.author","Hüffmeier, Ulrike"],["dc.date.accessioned","2022-09-01T09:49:41Z"],["dc.date.available","2022-09-01T09:49:41Z"],["dc.date.issued","2022"],["dc.description.sponsorship"," http://dx.doi.org/10.13039/501100001659 Deutsche Forschungsgemeinschaft"],["dc.identifier.doi","10.1016/j.jid.2021.12.021"],["dc.identifier.pii","S0022202X21026397"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113500"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.issn","0022-202X"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Transcriptomes of MPO-Deficient Patients with Generalized Pustular Psoriasis Reveals Expansion of CD4+ Cytotoxic T Cells and an Involvement of the Complement System"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","522"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Human Immunology"],["dc.bibliographiccitation.lastpage","524"],["dc.bibliographiccitation.volume","72"],["dc.contributor.author","Douroudis, Konstantinos"],["dc.contributor.author","Sirotkina, Meeli"],["dc.contributor.author","Kingo, Kuelli"],["dc.contributor.author","Moessner, Rotraut"],["dc.contributor.author","Koks, Sulev"],["dc.date.accessioned","2018-11-07T08:55:35Z"],["dc.date.available","2018-11-07T08:55:35Z"],["dc.date.issued","2011"],["dc.description.abstract","The PRO2268 gene encodes for the PRO2268 molecule and maps to a chromosomal region (12q14), which clusters genes with a key role in immune signaling. Although the PRO2268 protein is as yet of unknown function, we should not exclude the possibility that the PRO2268 gene, because of its location, might have a distinct role in autoimmunity and inflammation. The aim of the present study was to investigate the expression pattern of the PRO2268 protein in psoriasis skin. Formalin-fixed paraffin-embedded sections from normal and psoriasis skin tissue were studied immunohistochemically using custom-ordered antibodies (anti-PRO2268#1 and anti-PRO2268#2) against the PRO2268. The present study revealed an expression of the anti-PRO2268#2 in the inflammatory infiltrate, and suggesting a possible role for the PRO2268 molecule in pathophysiology of psoriasis, which needs further investigation. (C) 2011 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.humimm.2011.03.002"],["dc.identifier.isi","000291138900010"],["dc.identifier.pmid","21414369"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22940"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0198-8859"],["dc.title","Immunohistochemical expression of the PRO2268 protein in psoriasis vulgaris skin"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]