Now showing 1 - 4 of 4
  • 2015Conference Abstract
    [["dc.bibliographiccitation.firstpage","S394"],["dc.bibliographiccitation.journal","European Neuropsychopharmacology"],["dc.bibliographiccitation.lastpage","S395"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Schmaal, L."],["dc.contributor.author","Veltman, D. J."],["dc.contributor.author","van Erp, T. G."],["dc.contributor.author","Saemann, P. G."],["dc.contributor.author","Frodl, T."],["dc.contributor.author","Jahanshad, N."],["dc.contributor.author","Loehrer, E."],["dc.contributor.author","Tiemeier, Henning"],["dc.contributor.author","Hofman, Albert"],["dc.contributor.author","Niessen, W. J."],["dc.contributor.author","Vernooij, M. W."],["dc.contributor.author","Ikram, M. Arfan"],["dc.contributor.author","Wittfeld, K."],["dc.contributor.author","Grabe, Hans Joergen"],["dc.contributor.author","Block, Alan J."],["dc.contributor.author","Hegenscheid, K."],["dc.contributor.author","Voelzke, Henry"],["dc.contributor.author","Hoehn, D."],["dc.contributor.author","Czisch, Michael"],["dc.contributor.author","Lagopoulos, J."],["dc.contributor.author","Hatton, S. N."],["dc.contributor.author","Hickie, I. B."],["dc.contributor.author","Goya-Maldonado, Roberto"],["dc.contributor.author","Kraemer, Bernd"],["dc.contributor.author","Gruber, Oliver"],["dc.contributor.author","Couvy-Duchesne, B."],["dc.contributor.author","Renteria, M. E."],["dc.contributor.author","Strike, L. T."],["dc.contributor.author","Mills, N. T."],["dc.contributor.author","De Zubicaray, G. I."],["dc.contributor.author","McMahon, K. L."],["dc.contributor.author","Medland, Sarah E."],["dc.contributor.author","Martin, Nicholas G."],["dc.contributor.author","Gillespie, N. A."],["dc.contributor.author","Wright, Margaret J."],["dc.contributor.author","Hall, G. B."],["dc.contributor.author","MacQueen, Glenda"],["dc.contributor.author","Frey, Erwin"],["dc.contributor.author","Carballedo, A."],["dc.contributor.author","van Velzen, L. S."],["dc.contributor.author","van Tol, M. J."],["dc.contributor.author","van der Wee, N. J."],["dc.contributor.author","Veer, I. M."],["dc.contributor.author","Walter, H."],["dc.contributor.author","Schnell, K."],["dc.contributor.author","Schramm, E."],["dc.contributor.author","Normann, C."],["dc.contributor.author","Schoepf, D."],["dc.contributor.author","Konrad, Christian"],["dc.contributor.author","Zurowski, B."],["dc.contributor.author","Nickson, T."],["dc.contributor.author","McIntosh, Andrew M."],["dc.contributor.author","Papmeyer, M."],["dc.contributor.author","Whalley, H. C."],["dc.contributor.author","Sussmann, J. E."],["dc.contributor.author","Godlewska, B. R."],["dc.contributor.author","Cowen, P. J."],["dc.contributor.author","Fischer, F. H."],["dc.contributor.author","Rose, Matthias"],["dc.contributor.author","Penninx, B. W."],["dc.contributor.author","Thompson, Paul M."],["dc.contributor.author","Hibar, Derrek P."],["dc.date.accessioned","2018-11-07T09:52:05Z"],["dc.date.available","2018-11-07T09:52:05Z"],["dc.date.issued","2015"],["dc.identifier.isi","000365518200505"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36043"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.publisher.place","Amsterdam"],["dc.relation.conference","28th Congress of the European-College-of-Neuropsychopharmacology (ECNP)"],["dc.relation.eventlocation","Amsterdam, NETHERLANDS"],["dc.relation.issn","1873-7862"],["dc.relation.issn","0924-977X"],["dc.title","Structural brain alterations in major depression: findings from the ENIGMA Major Depressive Disorder Working Group"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article Discussion
    [["dc.bibliographiccitation.firstpage","726"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Molecular Psychiatry"],["dc.bibliographiccitation.lastpage","728"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Schmaal, L."],["dc.contributor.author","Veltman, D. J."],["dc.contributor.author","van Erp, Theo G. M."],["dc.contributor.author","Saemann, P. G."],["dc.contributor.author","Frodl, T."],["dc.contributor.author","Jahanshad, N."],["dc.contributor.author","Loehrer, E."],["dc.contributor.author","Vernooij, M. W."],["dc.contributor.author","Niessen, W. J."],["dc.contributor.author","Ikram, M. Arfan"],["dc.contributor.author","Wittfeld, K."],["dc.contributor.author","Grabe, Hans Joergen"],["dc.contributor.author","Block, Alan J."],["dc.contributor.author","Hegenscheid, K."],["dc.contributor.author","Hoehn, D."],["dc.contributor.author","Czisch, Michael"],["dc.contributor.author","Lagopoulos, J."],["dc.contributor.author","Hatton, S. N."],["dc.contributor.author","Hickie, I. B."],["dc.contributor.author","Goya-Maldonado, Roberto"],["dc.contributor.author","Kraemer, Bernd"],["dc.contributor.author","Gruber, Oliver"],["dc.contributor.author","Couvy-Duchesne, B."],["dc.contributor.author","Renteria, M. E."],["dc.contributor.author","Strike, L. T."],["dc.contributor.author","Wright, Margaret J."],["dc.contributor.author","de Zubicaray, G. I."],["dc.contributor.author","McMahon, K. L."],["dc.contributor.author","Medland, Sarah E."],["dc.contributor.author","Gillespie, N. A."],["dc.contributor.author","Hall, G. B."],["dc.contributor.author","van Velzen, L. S."],["dc.contributor.author","van Tol, M-J"],["dc.contributor.author","van der Wee, N. J."],["dc.contributor.author","Veer, I. M."],["dc.contributor.author","Walter, H."],["dc.contributor.author","Schramm, E."],["dc.contributor.author","Normann, C."],["dc.contributor.author","Schoepf, D."],["dc.contributor.author","Konrad, Christian"],["dc.contributor.author","Zurowski, B."],["dc.contributor.author","McIntosh, Andrew M."],["dc.contributor.author","Whalley, H. C."],["dc.contributor.author","Sussmann, J. E."],["dc.contributor.author","Godlewska, B. R."],["dc.contributor.author","Fischer, F. H."],["dc.contributor.author","Penninx, B. W."],["dc.contributor.author","Thompson, Paul M."],["dc.contributor.author","Hibar, Derrek P."],["dc.date.accessioned","2018-11-07T10:13:52Z"],["dc.date.available","2018-11-07T10:13:52Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1038/mp.2016.9"],["dc.identifier.isi","000376159600003"],["dc.identifier.pmid","26903270"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40511"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Nature Publishing Group"],["dc.relation.issn","1476-5578"],["dc.relation.issn","1359-4184"],["dc.title","Size matters; but so does what you do with it! Response"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","900"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Molecular Psychiatry"],["dc.bibliographiccitation.lastpage","909"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Schmaal, Lianne"],["dc.contributor.author","Hibar, Derek"],["dc.contributor.author","Sämann, P. G."],["dc.contributor.author","Hall, G. B."],["dc.contributor.author","Baune, Bernhard"],["dc.contributor.author","Jahanshad, Neda"],["dc.contributor.author","Cheung, J. W."],["dc.contributor.author","Erp, Theo G. M. van"],["dc.contributor.author","Bos, D."],["dc.contributor.author","Ikram, M. Arfan"],["dc.contributor.author","Vernooij, Meike W."],["dc.contributor.author","Niessen, W. J."],["dc.contributor.author","Tienson, Heather"],["dc.contributor.author","Hofman, A."],["dc.contributor.author","Wittfeld, Katharina"],["dc.contributor.author","Grabe, Hans-Jörgen"],["dc.contributor.author","Janowitz, Deborah"],["dc.contributor.author","Bülow, R."],["dc.contributor.author","Selonke, M."],["dc.contributor.author","Völzke, H."],["dc.contributor.author","Grotegerd, Dominik"],["dc.contributor.author","Dannlowski, Udo"],["dc.contributor.author","Arolt, Volker"],["dc.contributor.author","Opel, Nils"],["dc.contributor.author","Heindel, W."],["dc.contributor.author","Kugel, Harald"],["dc.contributor.author","Hoehn, David"],["dc.contributor.author","Czisch, Michael"],["dc.contributor.author","Couvy-Duchesne, B."],["dc.contributor.author","Renteria, Miguel E."],["dc.contributor.author","Strike, Lachlan T."],["dc.contributor.author","Wright, Margaret J."],["dc.contributor.author","Mills, N. T."],["dc.contributor.author","Zubicaray, Greig I. de"],["dc.contributor.author","McMahon, Katie L."],["dc.contributor.author","Medland, Sarah E."],["dc.contributor.author","Martin, Nicholas G."],["dc.contributor.author","Gillespie, N. A."],["dc.contributor.author","Goya-Maldonado, Roberto"],["dc.contributor.author","Gruber, Oliver"],["dc.contributor.author","Krämer, Bernd"],["dc.contributor.author","Hatton, S. N."],["dc.contributor.author","Lagopoulos, J."],["dc.contributor.author","Hickie, I. B."],["dc.contributor.author","Frodl, Thomas"],["dc.contributor.author","Carballedo, A."],["dc.contributor.author","Frey, E. M."],["dc.contributor.author","van Velzen, L. S."],["dc.contributor.author","Penninx, B. W. J. H."],["dc.contributor.author","van Tol, Marie-Jose"],["dc.contributor.author","Wee, Nic J. A. van der"],["dc.contributor.author","Davey, C. G."],["dc.contributor.author","Harrison, B. J."],["dc.contributor.author","Mwangi, Benson"],["dc.contributor.author","Cao, B."],["dc.contributor.author","Soares, Jair C."],["dc.contributor.author","Veer, I. M."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Schoepf, D."],["dc.contributor.author","Zurowski, B."],["dc.contributor.author","Konrad, C."],["dc.contributor.author","Schramm, E."],["dc.contributor.author","Normann, Claudia"],["dc.contributor.author","Schnell, K."],["dc.contributor.author","Sacchet, M. D."],["dc.contributor.author","Gotlib, I. H."],["dc.contributor.author","MacQueen, G. M."],["dc.contributor.author","Godlewska, B. R."],["dc.contributor.author","Nickson, T."],["dc.contributor.author","McIntosh, Andrew M."],["dc.contributor.author","Papmeyer, Martina"],["dc.contributor.author","Whalley, H. C."],["dc.contributor.author","Hall, Jeremy"],["dc.contributor.author","Sussmann, Jessika E."],["dc.contributor.author","Li, M."],["dc.contributor.author","Walter, M."],["dc.contributor.author","Aftanas, L."],["dc.contributor.author","Brack, I."],["dc.contributor.author","Bokhan, N. A."],["dc.contributor.author","Thompson, Paul M."],["dc.contributor.author","Veltman, Dick J."],["dc.date.accessioned","2017-09-07T11:47:51Z"],["dc.date.available","2017-09-07T11:47:51Z"],["dc.date.issued","2016"],["dc.description.abstract","The neuro-anatomical substrates of major depressive disorder (MDD) are still not well understood, despite many neuroimaging studies over the past few decades. Here we present the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorder Working Group on cortical structural alterations in MDD. Structural T1-weighted brain magnetic resonance imaging (MRI) scans from 2148 MDD patients and 7957 healthy controls were analysed with harmonized protocols at 20 sites around the world. To detect consistent effects of MDD and its modulators on cortical thickness and surface area estimates derived from MRI, statistical effects from sites were meta-analysed separately for adults and adolescents. Adults with MDD had thinner cortical gray matter than controls in the orbitofrontal cortex (OFC), anterior and posterior cingulate, insula and temporal lobes (Cohen's d effect sizes: -0.10 to -0.14). These effects were most pronounced in first episode and adult-onset patients (>21 years). Compared to matched controls, adolescents with MDD had lower total surface area (but no differences in cortical thickness) and regional reductions in frontal regions (medial OFC and superior frontal gyrus) and primary and higher-order visual, somatosensory and motor areas (d: -0.26 to -0.57). The strongest effects were found in recurrent adolescent patients. This highly powered global effort to identify consistent brain abnormalities showed widespread cortical alterations in MDD patients as compared to controls and suggests that MDD may impact brain structure in a highly dynamic way, with different patterns of alterations at different stages of life."],["dc.identifier.doi","10.1038/mp.2016.60"],["dc.identifier.gro","3150738"],["dc.identifier.pmid","27137745"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7527"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.relation.issn","1359-4184"],["dc.title","Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","177"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Biological Psychiatry"],["dc.bibliographiccitation.lastpage","186"],["dc.bibliographiccitation.volume","77"],["dc.contributor.author","Genzel, Lisa"],["dc.contributor.author","Dresler, Martin"],["dc.contributor.author","Cornu, Marion"],["dc.contributor.author","Jaeger, Eugen"],["dc.contributor.author","Konrad, Boris"],["dc.contributor.author","Adamczyk, Marek"],["dc.contributor.author","Friess, Elisabeth"],["dc.contributor.author","Steiger, Axel"],["dc.contributor.author","Czisch, Michael"],["dc.contributor.author","Goya-Maldonado, Roberto"],["dc.date.accessioned","2018-11-07T10:02:09Z"],["dc.date.available","2018-11-07T10:02:09Z"],["dc.date.issued","2015"],["dc.description.abstract","BACKGROUND: Overnight memory consolidation is disturbed in both depression and schizophrenia, creating an ideal situation to investigate the mechanisms underlying sleep-related consolidation and to distinguish disease-specific processes from common elements in their pathophysiology. METHODS: We investigated patients with depression and schizophrenia, as well as healthy control subjects (each n = 16), under a motor memory consolidation protocol with functional magnetic resonance imaging and polysomnography. RESULTS: In a sequential finger-tapping task associated with the degree of hippocampal-prefrontal cortex functional connectivity during the task, significantly less overnight improvement was identified as a common deficit in both patient groups. A task-related overnight decrease in activation of the basal ganglia was observed in control subjects and schizophrenia patients; in contrast, patients with depression showed an increase. During the task, schizophrenia patients, in comparison with control subjects, additionally recruited adjacent cortical areas, which showed a decrease in functional magnetic resonance imaging activation overnight and were related to disease severity. Effective connectivity analyses revealed that the hippocampus was functionally connected to the motor task network, and the cerebellum decoupled from this network overnight. CONCLUSIONS: While both patient groups showed similar deficits in consolidation associated with hippocampal-prefrontal cortex connectivity, other activity patterns more specific for disease pathology differed."],["dc.description.sponsorship","[ERC-2010-Ad6-268800-Neuroschema]"],["dc.identifier.doi","10.1016/j.biopsych.2014.06.004"],["dc.identifier.isi","000346386600013"],["dc.identifier.pmid","25037555"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38172"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1873-2402"],["dc.relation.issn","0006-3223"],["dc.title","Medial Prefrontal-Hippocampal Connectivity and Motor Memory Consolidation in Depression and Schizophrenia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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