Fuchs, Eberhard

[["dc.bibliographiccitation.firstpage","1025"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Biological Psychiatry"],["dc.bibliographiccitation.lastpage","1034"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Coe, Christopher L"],["dc.contributor.author","Kramer, Marian"],["dc.contributor.author","Czéh, Boldizsár"],["dc.contributor.author","Gould, Elizabeth"],["dc.contributor.author","Reeves, Alison J"],["dc.contributor.author","Kirschbaum, Clemens"],["dc.contributor.author","Fuchs, Eberhard"],["dc.date.accessioned","2022-10-06T13:33:38Z"],["dc.date.available","2022-10-06T13:33:38Z"],["dc.date.issued","2003"],["dc.identifier.doi","10.1016/S0006-3223(03)00698-X"],["dc.identifier.pii","S000632230300698X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115686"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0006-3223"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile Rhesus monkeys"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","290"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Brain Research"],["dc.bibliographiccitation.lastpage","293"],["dc.bibliographiccitation.volume","947"],["dc.contributor.author","Fischer, Anja K"],["dc.contributor.author","von Rosenstiel, Philipp"],["dc.contributor.author","Fuchs, Eberhard"],["dc.contributor.author","Goula, Daniel"],["dc.contributor.author","Almeida, Osborne F.X"],["dc.contributor.author","Czéh, Boldizsár"],["dc.date.accessioned","2022-10-06T13:33:39Z"],["dc.date.available","2022-10-06T13:33:39Z"],["dc.date.issued","2002"],["dc.identifier.doi","10.1016/S0006-8993(02)03042-1"],["dc.identifier.pii","S0006899302030421"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115691"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0006-8993"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","The prototypic mineralocorticoid receptor agonist aldosterone influences neurogenesis in the dentate gyrus of the adrenalectomized rat"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","43"],["dc.bibliographiccitation.issue","1-3"],["dc.bibliographiccitation.journal","European Journal of Pharmacology"],["dc.bibliographiccitation.lastpage","50"],["dc.bibliographiccitation.volume","598"],["dc.contributor.author","Michael-Titus, Adina T."],["dc.contributor.author","Albert, Monika"],["dc.contributor.author","Michael, Gregory J."],["dc.contributor.author","Michaelis, Thomas"],["dc.contributor.author","Watanabe, Takashi"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Pudovkina, Olga"],["dc.contributor.author","van der Hart, Marieke G.C."],["dc.contributor.author","Hesselink, Mayke B."],["dc.contributor.author","Fuchs, Eberhard"],["dc.contributor.author","Czéh, Boldizsár"],["dc.date.accessioned","2022-10-06T13:33:06Z"],["dc.date.available","2022-10-06T13:33:06Z"],["dc.date.issued","2008"],["dc.identifier.doi","10.1016/j.ejphar.2008.09.006"],["dc.identifier.pii","S0014299908009436"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115546"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0014-2999"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","SONU20176289, a compound combining partial dopamine D2 receptor agonism with specific serotonin reuptake inhibitor activity, affects neuroplasticity in an animal model for depression"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","369"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","MULTIPLE SCLEROSIS"],["dc.bibliographiccitation.lastpage","374"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Merkler, Doron"],["dc.contributor.author","Schmelting, Barthel"],["dc.contributor.author","Czeh, Boldizsar"],["dc.contributor.author","Fuchs, E."],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Brueck, Wolfgang"],["dc.date.accessioned","2018-11-07T09:30:14Z"],["dc.date.available","2018-11-07T09:30:14Z"],["dc.date.issued","2006"],["dc.description.abstract","Pathomorphological studies described pathological heterogeneity in patients with multiple sclerosis (MS). Different effector mechanisms might therefore be responsible for lesion formation in MS. The present report shows that myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) in common marmoset monkeys reflects one specific lesional subtype of MS, namely MS pattern 11 lesions with antibody/complement-mediated damage. MOG-induced EAE in marmoset monkeys will, therefore, provide an ideal model for therapeutic approaches directed against B-cell/antibody/complement in MS."],["dc.identifier.doi","10.1191/1352458506ms1290oa"],["dc.identifier.isi","000239431200002"],["dc.identifier.pmid","16900750"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31257"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.relation.issn","1352-4585"],["dc.title","Myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in the common marmoset reflects the immunopathology of pattern II multiple sclerosis lesions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","161"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","European Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","166"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Lucassen, Paul J."],["dc.contributor.author","Vollmann-Honsdorf, Gesa K."],["dc.contributor.author","Gleisberg, Mira"],["dc.contributor.author","Czéh, Boldizsár"],["dc.contributor.author","De Kloet, E. Ron"],["dc.contributor.author","Fuchs, Eberhard"],["dc.date.accessioned","2022-10-06T13:34:22Z"],["dc.date.available","2022-10-06T13:34:22Z"],["dc.date.issued","2001"],["dc.identifier.doi","10.1046/j.0953-816x.2001.01629.x"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115894"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0953-816X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Chronic psychosocial stress differentially affects apoptosis in hippocampal subregions and cortex of the adult tree shrew"],["dc.title.alternative","Apoptosis in the tree shrew hippocampus"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","548"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Psychopharmacology"],["dc.bibliographiccitation.lastpage","557"],["dc.bibliographiccitation.volume","180"],["dc.contributor.author","Czéh, Boldizsár"],["dc.contributor.author","Pudovkina, Olga"],["dc.contributor.author","van der Hart, Marieke G. C."],["dc.contributor.author","Simon, Mária"],["dc.contributor.author","Heilbronner, Urs"],["dc.contributor.author","Michaelis, Thomas"],["dc.contributor.author","Watanabe, Takashi"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Fuchs, Eberhard"],["dc.date.accessioned","2022-10-06T13:27:11Z"],["dc.date.available","2022-10-06T13:27:11Z"],["dc.date.issued","2005"],["dc.identifier.doi","10.1007/s00213-005-2184-8"],["dc.identifier.pii","2184"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115273"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1432-2072"],["dc.relation.issn","0033-3158"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Examining SLV-323, a novel NK1 receptor antagonist, in a chronic psychosocial stress model for depression"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Behavioural Brain Research"],["dc.bibliographiccitation.lastpage","13"],["dc.bibliographiccitation.volume","190"],["dc.contributor.author","Czeh, Boldizsar"],["dc.contributor.author","Perez-Cruz, Claudia"],["dc.contributor.author","Fuchs, Eberhard"],["dc.contributor.author","Fluegge, Gabriele"],["dc.date.accessioned","2018-11-07T11:13:53Z"],["dc.date.available","2018-11-07T11:13:53Z"],["dc.date.issued","2008"],["dc.description.abstract","The prefrontal cortex (PFC) is implicated in a number of higher cognitive functions as well as processing emotions and regulation of stress responses. Hemispheric specialization of the PFC in humans in emotional processing is well documented, and there is evidence that a similar functional lateralization is present in all mammals. Recent findings suggest the possibility of an intrinsic structural hemispheric asymmetry in the rat medial PFC (mPFC). Specifically, interhemispheric differences have been found in the architecture of pyramidal cell apical dendritic trees together with hemispheric asymmetry in cell proliferation including gliogenesis. It is now well established that chronic stress has a profound impact on neural plasticity in a number of corticolimbic structures and affects the etiology, pathophysiology, and therapeutic outcome of most psychiatric disorders. We summarize recent experimental data documenting pronounced dendritic remodeling of pyramidal cells and suppressed gliogenesis in the mPFC of rats subjected to chronic stress or to artificially elevated glucocorticoid levels. The stress affect on these structural elements seems to be hemispheric specific, often abolishing or even reversing natural asymmetries seen at the cellular level. We discuss these preclinical observations with respect to clinical findings that show impaired function, altered lateralization and histopathological changes in the PFC in psychiatric patients. We argue that it is important to define the kinds of structural changes that result from long-term stress exposure because this knowledge will improve the identification of cellular endophenotypes in various psychiatric disorders. (c) 2008 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.bbr.2008.02.031"],["dc.identifier.isi","000255766800001"],["dc.identifier.pmid","18384891"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54000"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0166-4328"],["dc.title","Chronic stress-induced cellular changes in the medial prefrontal cortex and their potential clinical implications: Does hemisphere location matter?"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1146"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","British Journal of Pharmacology"],["dc.bibliographiccitation.lastpage","1186"],["dc.bibliographiccitation.volume","179"],["dc.contributor.author","Borbély, Éva"],["dc.contributor.author","Simon, Mária"],["dc.contributor.author","Fuchs, Eberhard"],["dc.contributor.author","Wiborg, Ove"],["dc.contributor.author","Czéh, Boldizsár"],["dc.contributor.author","Helyes, Zsuzsanna"],["dc.date.accessioned","2022-10-06T13:24:59Z"],["dc.date.available","2022-10-06T13:24:59Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1111/bph.15753"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114722"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1476-5381"],["dc.relation.issn","0007-1188"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Novel drug developmental strategies for treatment‐resistant depression"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","933"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Molecular Psychiatry"],["dc.bibliographiccitation.lastpage","941"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","van der Hart, M G C"],["dc.contributor.author","Czéh, B"],["dc.contributor.author","de Biurrun, G"],["dc.contributor.author","Michaelis, T"],["dc.contributor.author","Watanabe, T"],["dc.contributor.author","Natt, O"],["dc.contributor.author","Frahm, J"],["dc.contributor.author","Fuchs, E"],["dc.date.accessioned","2022-10-06T13:34:20Z"],["dc.date.available","2022-10-06T13:34:20Z"],["dc.date.issued","2002"],["dc.identifier.doi","10.1038/sj.mp.4001130"],["dc.identifier.pii","BF4001130"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115886"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1476-5578"],["dc.relation.issn","1359-4184"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.rights.uri","https://www.springer.com/tdm"],["dc.title","Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","738"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","European Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","747"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Perez-Cruz, Claudia"],["dc.contributor.author","Simon, Maria"],["dc.contributor.author","Czeh, Boldizsar"],["dc.contributor.author","Fluegge, Gabriele"],["dc.contributor.author","Fuchs, Eberhard"],["dc.date.accessioned","2018-11-07T08:33:00Z"],["dc.date.available","2018-11-07T08:33:00Z"],["dc.date.issued","2009"],["dc.description.abstract","Pyramidal neurons of the rat medial prefrontal cortex have been shown to react to chronic stress by retracting their apical dendrites and by spine loss. We extended these findings by focusing on the basilar dendritic tree of layer III pyramidal neurons in both hemispheres of the rat prelimbic cortex. Animals were subjected to daily restraint stress for 1 week (6 h/day), during either the resting or the activity period. The morphology of basilar dendrites and spines of Golgi-Cox-stained neurons in the left and right hemispheres was digitally reconstructed and analyzed. We observed the following: (i) there was an inherent hemispheric asymmetry in control rats during the resting period: the number of spines on proximal dendrites was higher in the left than in the right hemisphere; (ii) basal dendrites in controls displayed a diurnal variation: there was more dendritic material during the resting period than in the activity period; (iii) chronic stress reduced the length of basal dendrites in only the right prelimbic cortex; (iv) chronic stress reduced spine density on proximal basal dendrites; (v) restraint stress during the activity period had more pronounced effects on the physiological stress parameters than restraint stress during the resting period. Our results show dynamic hemisphere-dependent structural changes in pyramidal neurons of the rat prelimbic cortex that are tightly linked to periods of resting and activity. These morphological alterations reflect the capacity of the neurons to react to external stimuli and mirror presumptive changes in neuronal communication."],["dc.identifier.doi","10.1111/j.1460-9568.2009.06622.x"],["dc.identifier.isi","000263451700008"],["dc.identifier.pmid","19200065"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17466"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell Publishing, Inc"],["dc.relation.issn","0953-816X"],["dc.title","Hemispheric differences in basilar dendrites and spines of pyramidal neurons in the rat prelimbic cortex: activity- and stress-induced changes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]