Teichmann, Thomas

[["dc.bibliographiccitation.firstpage","3627"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"],["dc.bibliographiccitation.lastpage","3632"],["dc.bibliographiccitation.volume","110"],["dc.contributor.author","Loefke, Christian"],["dc.contributor.author","Zwiewka, Marta"],["dc.contributor.author","Heilmann, Ingo"],["dc.contributor.author","van Montagu, Marc C. E."],["dc.contributor.author","Teichmann, Thomas"],["dc.contributor.author","Friml, Jiri"],["dc.date.accessioned","2018-11-07T09:28:00Z"],["dc.date.available","2018-11-07T09:28:00Z"],["dc.date.issued","2013"],["dc.description.abstract","Gravitropic bending of plant organs is mediated by an asymmetric signaling of the plant hormone auxin between the upper and lower side of the respective organ. Here, we show that also another plant hormone, gibberellie acid (GA), shows asymmetric action during gravitropic responses. lmmunodetection using an antibody against GA and monitoring GA signaling output by downstream degradation of DELLA proteins revealed an asymmetric GA distribution and response with the maximum at the lower side of gravistimulated roots. Genetic or pharmacological manipulation of GA levels or response affects gravity-mediated auxin redistribution and root bending response. The higher GA levels at the lower side of the root correlate with increased amounts of PIN-FORMED2 (PIN2) auxin transporter at the plasma membrane. The observed increase in PIN2 stability is caused by a specific GA effect on trafficking of PIN proteins to lytic vacuoles that presumably occurs downstream of brefeldin A-sensitive endosomes. Our results suggest that asymmetric auxin distribution instructive for gravity-induced differential growth is consolidated by the asymmetric action of GA that stabilizes the PIN-dependent auxin stream along the lower side of gravistimulated roots."],["dc.identifier.doi","10.1073/pnas.1300107110"],["dc.identifier.isi","000315841900083"],["dc.identifier.pmid","23391733"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30671"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Natl Acad Sciences"],["dc.relation.issn","0027-8424"],["dc.title","Asymmetric gibberellin signaling regulates vacuolar trafficking of PIN auxin transporters during root gravitropism"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","855"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Developmental Cell"],["dc.bibliographiccitation.lastpage","866"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Zhang, Jing"],["dc.contributor.author","Vanneste, Steffen"],["dc.contributor.author","Brewer, Philip B."],["dc.contributor.author","Michniewicz, Marta"],["dc.contributor.author","Grones, Peter"],["dc.contributor.author","Kleine-Vehn, Juergen"],["dc.contributor.author","Loefke, Christian"],["dc.contributor.author","Teichmann, Thomas"],["dc.contributor.author","Bielach, Agnieszka"],["dc.contributor.author","Cannoot, Bernard"],["dc.contributor.author","Hoyerova, Klara"],["dc.contributor.author","Chen, X. U."],["dc.contributor.author","Xue, H. W."],["dc.contributor.author","Benkova, Eva"],["dc.contributor.author","Zazimalova, Eva"],["dc.contributor.author","Friml, Jiri"],["dc.date.accessioned","2018-11-07T08:55:06Z"],["dc.date.available","2018-11-07T08:55:06Z"],["dc.date.issued","2011"],["dc.description.abstract","The phytohormone auxin is an important determinant of plant development. Directional auxin flow within tissues depends on polar localization of PIN auxin transporters. To explore regulation of PIN-mediated auxin transport, we screened for suppressors of PIN1 overexpression (supo) and identified an inositol polyphosphate 1-phosphatase mutant (supo1), with elevated inositol trisphosphate (InsP(3)) and cytosolic Ca2+ levels. Pharmacological and genetic increases in InsP(3) or Ca2+ levels also suppressed the PIN1 gain-of-function phenotypes and caused defects in basal PIN localization, auxin transport and auxin-mediated development. In contrast, the reductions in InsP(3) levels and Ca2+ signaling antagonized the effects of the supo1 mutation and disrupted preferentially apical PIN localization. InsP(3) and Ca2+ are evolutionarily conserved second messengers involved in various cellular functions, particularly stress responses. Our findings implicate them as modifiers of cell polarity and polar auxin transport, and highlight a potential integration point through which Ca2+ signaling-related stimuli could influence auxin-mediated development."],["dc.identifier.doi","10.1016/j.devcel.2011.05.013"],["dc.identifier.isi","000291763500013"],["dc.identifier.pmid","21664582"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22828"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.relation.issn","1534-5807"],["dc.title","Inositol Trisphosphate-Induced Ca2+ Signaling Modulates Auxin Transport and PIN Polarity"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1554"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"],["dc.bibliographiccitation.lastpage","1559"],["dc.bibliographiccitation.volume","109"],["dc.contributor.author","Grunewald, Wim"],["dc.contributor.author","De Smet, Ive"],["dc.contributor.author","Lewis, Daniel R."],["dc.contributor.author","Loefke, Christian"],["dc.contributor.author","Jansen, Leentje"],["dc.contributor.author","Goeminne, Geert"],["dc.contributor.author","Bossche, Robin Vanden"],["dc.contributor.author","Karimi, Mansour"],["dc.contributor.author","De Rybel, Bert"],["dc.contributor.author","Vanholme, Bartel"],["dc.contributor.author","Teichmann, Thomas"],["dc.contributor.author","Boerjan, Wout"],["dc.contributor.author","van Montagu, Marc C. E."],["dc.contributor.author","Gheysen, Godelieve"],["dc.contributor.author","Muday, Gloria K."],["dc.contributor.author","Friml, Jiri"],["dc.contributor.author","Beeckman, Tom"],["dc.date.accessioned","2018-11-07T09:14:11Z"],["dc.date.available","2018-11-07T09:14:11Z"],["dc.date.issued","2012"],["dc.description.abstract","Gradients of the plant hormone auxin, which depend on its active intercellular transport, are crucial for the maintenance of root meristematic activity. This directional transport is largely orchestrated by a complex interaction of specific influx and efflux carriers that mediate the auxin flow into and out of cells, respectively. Besides these transport proteins, plant-specific polyphenolic compounds known as flavonols have been shown to act as endogenous regulators of auxin transport. However, only limited information is available on how flavonol synthesis is developmentally regulated. Using reduction-of-function and overexpression approaches in parallel, we demonstrate that the WRKY23 transcription factor is needed for proper root growth and development by stimulating the local biosynthesis of flavonols. The expression of WRKY23 itself is controlled by auxin through the AUXIN RESPONSE FACTOR 7 (ARF7) and ARF19 transcriptional response pathway. Our results suggest a model in which WRKY23 is part of a transcriptional feedback loop of auxin on its own transport through local regulation of flavonol biosynthesis."],["dc.identifier.doi","10.1073/pnas.1121134109"],["dc.identifier.isi","000299731400046"],["dc.identifier.pmid","22307611"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27350"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Natl Acad Sciences"],["dc.relation.issn","0027-8424"],["dc.title","Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1920"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","The Plant Cell"],["dc.bibliographiccitation.lastpage","1931"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Kitakura, Saeko"],["dc.contributor.author","Vanneste, Steffen"],["dc.contributor.author","Robert, Stephanie"],["dc.contributor.author","Lofke, Christian"],["dc.contributor.author","Teichmann, Thomas"],["dc.contributor.author","Tanaka, Hirokazu"],["dc.contributor.author","Friml, Jiri"],["dc.date.accessioned","2018-11-07T08:56:42Z"],["dc.date.available","2018-11-07T08:56:42Z"],["dc.date.issued","2011"],["dc.description.abstract","Endocytosis is a crucial mechanism by which eukaryotic cells internalize extracellular and plasma membrane material, and it is required for a multitude of cellular and developmental processes in unicellular and multicellular organisms. In animals and yeast, the best characterized pathway for endocytosis depends on the function of the vesicle coat protein clathrin. Clathrin-mediated endocytosis has recently been demonstrated also in plant cells, but its physiological and developmental roles remain unclear. Here, we assessed the roles of the clathrin-mediated mechanism of endocytosis in plants by genetic means. We interfered with clathrin heavy chain (CHC) function through mutants and dominant-negative approaches in Arabidopsis thaliana and established tools to manipulate clathrin function in a cell type-specific manner. The chc2 single mutants and dominant-negative CHC1 (HUB) transgenic lines were defective in bulk endocytosis as well as in internalization of prominent plasma membrane proteins. Interference with clathrin-mediated endocytosis led to defects in constitutive endocytic recycling of PIN auxin transporters and their polar distribution in embryos and roots. Consistent with this, these lines had altered auxin distribution patterns and associated auxin transport-related phenotypes, such as aberrant embryo patterning, imperfect cotyledon specification, agravitropic growth, and impaired lateral root organogenesis. Together, these data demonstrate a fundamental role for clathrin function in cell polarity, growth, patterning, and organogenesis in plants."],["dc.identifier.doi","10.1105/tpc.111.083030"],["dc.identifier.isi","000292079800019"],["dc.identifier.pmid","21551390"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23212"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Plant Biologists"],["dc.relation.issn","1040-4651"],["dc.title","Clathrin Mediates Endocytosis and Polar Distribution of PIN Auxin Transporters in Arabidopsis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]