Lippert, Undine

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European Journal of Immunology"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Zachmann, Karolin"],["dc.contributor.author","Ferrari, David M."],["dc.contributor.author","Schwarz, Herbert"],["dc.contributor.author","Brunner, Edgar"],["dc.contributor.author","Latif, A. H. M. Mahbub"],["dc.contributor.author","Neumann, Christine"],["dc.contributor.author","Soruri, Afsaneh"],["dc.date.accessioned","2018-11-07T11:14:25Z"],["dc.date.available","2018-11-07T11:14:25Z"],["dc.date.issued","2008"],["dc.format.extent","1767"],["dc.identifier.doi","10.1002/eji.200737800"],["dc.identifier.isi","000256762400030"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54117"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-v C H Verlag Gmbh"],["dc.relation.haserratum","/handle/2/97655"],["dc.relation.issn","0014-2980"],["dc.title","CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response (vol 38, pg 1024, 2008)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Investigative Dermatology"],["dc.bibliographiccitation.volume","125"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Zachmann, Karolin"],["dc.contributor.author","Brunner, E."],["dc.contributor.author","Lafti, A. H."],["dc.contributor.author","Ferrari, David M."],["dc.contributor.author","Neumann, C."],["dc.contributor.author","Soruri, Afsaneh"],["dc.date.accessioned","2018-11-07T10:56:17Z"],["dc.date.available","2018-11-07T10:56:17Z"],["dc.date.issued","2005"],["dc.format.extent","A49"],["dc.identifier.isi","000231862600286"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49976"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Nature Publishing Group"],["dc.publisher.place","New york"],["dc.relation.conference","35th Annual Meeting of the European-Society-for-Dermatological-Research"],["dc.relation.eventlocation","Tubingen, GERMANY"],["dc.relation.issn","0022-202X"],["dc.title","CD137 ligand mediated differentiation of immature human dendritic cells is associated with enhanced (antigen specific) T cell activation"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","11213"],["dc.bibliographiccitation.issue","15"],["dc.bibliographiccitation.journal","Journal of Biological Chemistry"],["dc.bibliographiccitation.lastpage","11220"],["dc.bibliographiccitation.volume","282"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Diao, Daojun"],["dc.contributor.author","Barak, Naomi N."],["dc.contributor.author","Ferrari, David M."],["dc.date.accessioned","2018-11-07T11:03:12Z"],["dc.date.available","2018-11-07T11:03:12Z"],["dc.date.issued","2007"],["dc.description.abstract","The structure and mode of binding of the endoplasmic reticulum protein disulfide isomerase-related proteins to their substrates is currently a focus of intensive research. We have recently determined the crystal structure of the Drosophila melanogaster protein disulfide isomerase-related protein Wind and have described two essential substrate binding sites within the protein, one within the thioredoxin b-domain and another within the C-terminal D-domain. Although a mammalian ortholog of Wind ( ERp29/28) is known, conflicting interpretations of its structure and putative function have been postulated. Here, we have provided evidence indicating that ERp29 is indeed similar in both structure and function to its Drosophila ortholog. Using a site-directed mutagenesis approach, we have demonstrated that homodimerization of the b-domains is significantly reduced in vitro upon replacement of key residues at the predicted dimerization interface. Investigation of Wind-ERp29 fusion constructs showed that mutants of the D-domain of ERp29 prevent transport of a substrate protein ( Pipe) in a manner consistent with the presence of a discrete, conserved peptide binding site in the D-domain. Finally, we have highlighted the general applicability of these findings by showing that the D-domain of a redox-active disulfide isomerase, from the slime mold Dictyostelium discoideum, can also functionally replace the Wind D-domain in vivo."],["dc.identifier.doi","10.1074/jbc.M604440200"],["dc.identifier.isi","000245941500043"],["dc.identifier.pmid","17296603"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51562"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Biochemistry Molecular Biology Inc"],["dc.relation.issn","0021-9258"],["dc.title","Conserved structural and functional properties of D-domain containing redox-active and -inactive protein disulfide isomerase-related protein chaperones"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Hoyer, Peter F."],["dc.contributor.author","Ferrari, David M."],["dc.date.accessioned","2018-11-07T10:17:15Z"],["dc.date.available","2018-11-07T10:17:15Z"],["dc.date.issued","2016"],["dc.format.extent","E7"],["dc.identifier.isi","000373072800041"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41197"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","43rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung-e-V (ADF)"],["dc.relation.eventlocation","Vienna, AUSTRIA"],["dc.relation.issn","1600-0625"],["dc.relation.issn","0906-6705"],["dc.title","Decreased expression of CD49d in monocytes of ERp29(-/-) mice"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","215"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","223"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Bork, Konrad"],["dc.contributor.author","Zibat, Arne"],["dc.contributor.author","Ferrari, David M."],["dc.contributor.author","Wollnik, Bernd"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Wulff, Karin"],["dc.contributor.author","Lippert, Undine"],["dc.date.accessioned","2020-12-10T18:27:21Z"],["dc.date.available","2020-12-10T18:27:21Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1111/ddg.14036"],["dc.identifier.eissn","1610-0387"],["dc.identifier.issn","1610-0379"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76319"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Hereditary angioedema in a single family with specific mutations in both plasminogen and SERPING1 genes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3479"],["dc.bibliographiccitation.issue","18"],["dc.bibliographiccitation.journal","FEBS Letters"],["dc.bibliographiccitation.lastpage","3484"],["dc.bibliographiccitation.volume","581"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Ferrari, David M."],["dc.contributor.author","Jahn, Reinhard"],["dc.date.accessioned","2018-11-07T11:00:36Z"],["dc.date.available","2018-11-07T11:00:36Z"],["dc.date.issued","2007"],["dc.description.abstract","Mast cells are important players in innate immunity and mediate allergic responses. Upon stimulation, they release biologically active mediators including histamine, cytokines and lysosomal hydrolases. We used permeabilized rat basophilic leukaemia cells as model to identify R-SNAREs (soluble NSF (N-ethylmaleimide-sensitive fusion protein)) mediating exocytosis of hexosaminidase from mast cells. Of a complete set of recombinant mammalian R-SNAREs, only vesicle associated membrane protein (VAMP8)/endobrevin consistently blocked hexosaminidase release, which was also insensitive to treatment with clostridial neurotoxins. Thus, VAMP8, which also mediates fusion of late endosomes and lysosomes, plays a major role in hexosaminidase release, strengthening the view that mast cell granules share properties of both secretory granules and lysosomes. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.febslet.2007.06.057"],["dc.identifier.isi","000248473200026"],["dc.identifier.pmid","17618625"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50958"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0014-5793"],["dc.title","Endobrevin/VAMP8 mediates exocytotic release of hexosaminidase from rat basophilic leukaemia cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Zachmann, Karolin"],["dc.contributor.author","Ferrari, David M."],["dc.contributor.author","Schwarz, H."],["dc.contributor.author","Brunner, E."],["dc.contributor.author","Latif, A. H. M. Mahbub"],["dc.contributor.author","Neumann, C."],["dc.contributor.author","Soruri, Afsaneh"],["dc.date.accessioned","2018-11-07T10:12:05Z"],["dc.date.available","2018-11-07T10:12:05Z"],["dc.date.issued","2006"],["dc.format.extent","201"],["dc.identifier.isi","000235370600050"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40169"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","33rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF)"],["dc.relation.eventlocation","Aachen, GERMANY"],["dc.relation.issn","0906-6705"],["dc.title","CD137 ligand induced differentiation of human dendritic cells to potent activators of antigen-specific T cells"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Babina, M."],["dc.contributor.author","Ferrari, David M."],["dc.contributor.author","Schwarz, H."],["dc.contributor.author","Zachmann, Karolin"],["dc.contributor.author","Knosalla, M."],["dc.contributor.author","Middel, Peter"],["dc.contributor.author","Neumann, C."],["dc.date.accessioned","2018-11-07T11:04:24Z"],["dc.date.available","2018-11-07T11:04:24Z"],["dc.date.issued","2007"],["dc.format.extent","226"],["dc.identifier.isi","000244056600108"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51836"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","34th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung"],["dc.relation.eventlocation","Freiburg, GERMANY"],["dc.relation.issn","0906-6705"],["dc.title","Expression and function of CD137 receptor and ligand in human mast cells"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","41"],["dc.bibliographiccitation.journal","Allergy"],["dc.bibliographiccitation.lastpage","42"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Zachmann, Karolin"],["dc.contributor.author","Ferrari, David M."],["dc.contributor.author","Schwarz, H."],["dc.contributor.author","Neumann, C."],["dc.contributor.author","Brunner, E."],["dc.contributor.author","Ul-Latif, A."],["dc.contributor.author","Soruri, Afsaneh"],["dc.date.accessioned","2018-11-07T11:01:31Z"],["dc.date.available","2018-11-07T11:01:31Z"],["dc.date.issued","2007"],["dc.identifier.isi","000246800000102"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51169"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.conference","26th Congress of the European-Academy-of-Allergology-and-Clinical-Immunology"],["dc.relation.eventlocation","Gothenburg, SWEDEN"],["dc.relation.issn","0105-4538"],["dc.title","Possible bidirectional function of CD137 ligand expressed on dendritic cells in antigen specific T cell activation"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Lippert, Undine"],["dc.contributor.author","Zachmann, Karolin"],["dc.contributor.author","Ferrari, David M."],["dc.contributor.author","Schwarz, H."],["dc.contributor.author","Neumann, C."],["dc.contributor.author","Soruri, Afsaneh"],["dc.date.accessioned","2018-11-07T11:17:36Z"],["dc.date.available","2018-11-07T11:17:36Z"],["dc.date.issued","2008"],["dc.format.extent","249"],["dc.identifier.isi","000252897700058"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54845"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.publisher.place","Oxford"],["dc.relation.conference","35th Annual Meeting of the Arbeitsgemeinschaft-Dermatolog-Forschung"],["dc.relation.eventlocation","Eriangen, GERMANY"],["dc.relation.issn","0906-6705"],["dc.title","CD137 ligand induces dendritic cell maturation and migration via TNF-alpha? and CCR7"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]