Now showing 1 - 10 of 11
  • 2022Journal Article
    [["dc.bibliographiccitation.firstpage","703"],["dc.bibliographiccitation.issue","09"],["dc.bibliographiccitation.journal","Allergologie"],["dc.bibliographiccitation.lastpage","711"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Lex, C."],["dc.contributor.author","Beutner, D."],["dc.contributor.author","Buhl, T."],["dc.contributor.author","Czech-Zechmeister, B.A."],["dc.contributor.author","Dombrowski, T."],["dc.contributor.author","Ellenrieder, V."],["dc.contributor.author","Fischer, A."],["dc.contributor.author","Geier, J."],["dc.contributor.author","Gliem, N."],["dc.contributor.author","Hasenfuß, G."],["dc.contributor.author","Beutner, C."],["dc.date.accessioned","2022-12-01T08:31:49Z"],["dc.date.available","2022-12-01T08:31:49Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.5414/ALX02350"],["dc.identifier.pii","02350"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118274"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-621"],["dc.relation.issn","0344-5062"],["dc.title","Allergiezentrum Südniedersachsen – Das Comprehensive Allergy Center der Universitätsmedizin Göttingen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2002Journal Article
    [["dc.bibliographiccitation.firstpage","290"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Brain Research"],["dc.bibliographiccitation.lastpage","293"],["dc.bibliographiccitation.volume","947"],["dc.contributor.author","Fischer, Anja K"],["dc.contributor.author","von Rosenstiel, Philipp"],["dc.contributor.author","Fuchs, Eberhard"],["dc.contributor.author","Goula, Daniel"],["dc.contributor.author","Almeida, Osborne F.X"],["dc.contributor.author","Czéh, Boldizsár"],["dc.date.accessioned","2022-10-06T13:33:39Z"],["dc.date.available","2022-10-06T13:33:39Z"],["dc.date.issued","2002"],["dc.identifier.doi","10.1016/S0006-8993(02)03042-1"],["dc.identifier.pii","S0006899302030421"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115691"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0006-8993"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","The prototypic mineralocorticoid receptor agonist aldosterone influences neurogenesis in the dentate gyrus of the adrenalectomized rat"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2010Journal Article
    [["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","Physical Review. B"],["dc.bibliographiccitation.volume","82"],["dc.contributor.author","Steeb, F."],["dc.contributor.author","Mathias, Stefan"],["dc.contributor.author","Wiesenmayer, M."],["dc.contributor.author","Fischer, A."],["dc.contributor.author","Aeschlimann, M."],["dc.contributor.author","Bauer, M."],["dc.contributor.author","Gauyacq, J. P."],["dc.date.accessioned","2021-03-05T08:58:53Z"],["dc.date.available","2021-03-05T08:58:53Z"],["dc.date.issued","2010"],["dc.identifier.doi","10.1103/PhysRevB.82.165430"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80287"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-393"],["dc.relation.eissn","1550-235X"],["dc.relation.issn","1098-0121"],["dc.title","Probing adsorbate dynamics with chirped laser pulses in a single-pulse scheme"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2007Journal Article
    [["dc.bibliographiccitation.firstpage","133"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Differentiation"],["dc.bibliographiccitation.lastpage","146"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","Blum, Martin"],["dc.contributor.author","Andre, Philipp"],["dc.contributor.author","Muders, Kerstin"],["dc.contributor.author","Schweickert, Axel"],["dc.contributor.author","Fischer, Anja K."],["dc.contributor.author","Bitzer, Eva"],["dc.contributor.author","Bogusch, Susanne"],["dc.contributor.author","Beyer, Tina"],["dc.contributor.author","van Straaten, Henny W. M."],["dc.contributor.author","Viebahn, Christoph"],["dc.date.accessioned","2018-11-07T11:05:11Z"],["dc.date.available","2018-11-07T11:05:11Z"],["dc.date.issued","2007"],["dc.description.abstract","The mammalian node, the functional equivalent of the frog dorsal blastoporal lip (Spemann's organizer), was originally described by Viktor Hensen in 1876 in the rabbit embryo as a mass of cells at the anterior end of the primitive streak. Today, the term \"node\" is commonly used to describe a bilaminar epithelial groove presenting itself as an indentation or \"pit\" at the distal tip of the mouse egg cylinder, and cilia on its ventral side are held responsible for molecular laterality (left-right) determination. We find that Hensen's node in the rabbit is devoid of cilia, and that ciliated cells are restricted to the notochordal plate, which emerges from the node rostrally. In a comparative approach, we use the organizer marker gene Goosecoid (Gsc) to show that a region of densely packed epithelium-like cells at the anterior end of the primitive streak represents the node in mouse and rabbit and is covered ventrally by a hypoblast (termed \"visceral endoderm\" in the mouse). Expression of Nodal, a gene intricately involved in the determination of vertebrate laterality, delineates the wide plate-like posterior segment of the notochord in the rabbit and mouse, which in the latter is represented by the indentation frequently termed \"the node.\" Similarly characteristic ciliation and nodal expression exists in Xenopus neurula embryos in the gastrocoel roof plate (GRP), i.e., at the posterior end of the notochord anterior to the blastoporal lip. Our data suggest that (1) a posterior segment of the notochord, here termed PNC (for posterior notochord), is characterized by features known to be involved in laterality determination, (2) the GRP in Xenopus is equivalent to the mammalian PNC, and (3) the mammalian node as defined by organizer gene expression is devoid of cilia and most likely not directly involved in laterality determination."],["dc.identifier.doi","10.1111/j.1432-0436.2006.00124.x"],["dc.identifier.isi","000244227500005"],["dc.identifier.pmid","17316383"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52012"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0301-4681"],["dc.title","Ciliation and gene expression distinguish between node and posterior notochord in the mammalian embryo"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2009Journal Article
    [["dc.bibliographiccitation.firstpage","013016"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","New Journal of Physics"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Steeb, F"],["dc.contributor.author","Mathias, S."],["dc.contributor.author","Fischer, A."],["dc.contributor.author","Wiesenmayer, M."],["dc.contributor.author","Aeschlimann, M"],["dc.contributor.author","Bauer, M."],["dc.date.accessioned","2021-03-05T08:58:50Z"],["dc.date.available","2021-03-05T08:58:50Z"],["dc.date.issued","2009"],["dc.identifier.doi","10.1088/1367-2630/11/1/013016"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80272"],["dc.notes.intern","DOI Import GROB-393"],["dc.relation.eissn","1367-2630"],["dc.title","The nature of a nonlinear excitation pathway from the Shockley surface state as probed by chirped pulse two photon photoemission"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2007Journal Article
    [["dc.bibliographiccitation.firstpage","3807"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","3812"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Nitsche, Michael A."],["dc.contributor.author","Roth, Amelie"],["dc.contributor.author","Kuo, Min-Fang"],["dc.contributor.author","Fischer, Anja K."],["dc.contributor.author","Liebetanz, David"],["dc.contributor.author","Lang, Nicolas"],["dc.contributor.author","Tergau, Frithjof"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T11:03:16Z"],["dc.date.available","2018-11-07T11:03:16Z"],["dc.date.issued","2007"],["dc.description.abstract","Associative neuroplasticity, which encompasses the modification of synaptic strength by coactivation of two synaptic inputs, has been linked to learning processes. Because unlimited plasticity destabilizes neuronal networks, homeostatic rules were proposed and experimentally proven that control for the amount and direction of plasticity dependent on background network activity. Accordingly, low background activity would enhance facilitatory plasticity, whereas high background activity would inhibit it. However, the impact of background excitability on associative plasticity has not been studied so far in humans. Facilitatory associative plasticity was induced by paired associative stimulation (PAS) in the human motor cortex, whereas background activity was enhanced or diminished by transcranial direct current stimulation (tDCS). When applied before PAS, excitability-enhancing tDCS also boosted the efficacy of PAS, whereas excitability-diminishing tDCS turned it into inhibition. Thus, previous background activity does not influence associative plasticity homeostatically. When tDCS and PAS were applied simultaneously, now in accordance with homeostatic rules of neuroplasticity, reduced background activity resulted in a prolonged excitability enhancement by PAS, whereas enhanced background activity turned it into inhibition. We conclude that background network activity can influence associative plasticity homeostatically. However, only simultaneous modulation of both parameters is in accordance with homeostatic concepts. These findings might be of importance for the development of plasticity-inducing stimulation protocols supporting information processing in humans."],["dc.identifier.doi","10.1523/JNEUROSCI.5348-06.2007"],["dc.identifier.isi","000245468300022"],["dc.identifier.pmid","17409245"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51577"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Soc Neuroscience"],["dc.relation.issn","0270-6474"],["dc.title","Timing-dependent modulation of associative plasticity by general network excitability in the human motor cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","521"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Optimization"],["dc.bibliographiccitation.lastpage","546"],["dc.bibliographiccitation.volume","66"],["dc.contributor.author","Aichholzer, Oswin"],["dc.contributor.author","Fischer, Anja K."],["dc.contributor.author","Fischer, Frank"],["dc.contributor.author","Meier, J. Fabian"],["dc.contributor.author","Pferschy, Ulrich"],["dc.contributor.author","Pilz, Alexander"],["dc.contributor.author","Stanek, Rostislav"],["dc.date.accessioned","2018-11-07T10:28:57Z"],["dc.date.available","2018-11-07T10:28:57Z"],["dc.date.issued","2017"],["dc.description.abstract","The travelling salesman problem (TSP) asks for a shortest tour through all vertices of a graph with respect to the weights of the edges. The symmetric quadratic travelling salesman problem (SQTSP) associates a weight with every three vertices traversed in succession. If these weights correspond to the turning angles of the tour, we speak of the angular-metric travelling salesman problem (Angle TSP). In this paper, we first consider the SQTSP from a computational point of view. In particular, we apply a rather basic algorithmic idea and perform the separation of the classical subtour elimination constraints on integral solutions only. Surprisingly, it turns out that this approach is faster than the standard fractional separation procedure known from the literature. We also test the combination with strengthened subtour elimination constraints for both variants, but these turn out to slow down the computation. Secondly, we provide a completely different, mathematically interesting MILP linearization for the Angle TSP that needs only a linear number of additional variables while the standard linearization requires a cubic one. For medium-sized instances of a variant of the Angle TSP, this formulation yields reduced running times. However, for larger instances or pure Angle TSP instances, the new formulation takes more time to solve than the known standard model. Finally, we introduce MaxSQTSP, the maximization version of the quadratic travelling salesman problem. Here, it turns out that using some of the stronger subtour elimination constraints helps. For the special case of the MaxAngle TSP, we can observe an interesting geometric property if the number of vertices is odd. We show that the sum of inner turning angles in an optimal solution always equals p. This implies that the problem can be solved by the standard ILP modelwithout producing any integral subtours. Moreover, we give a simple constructive polynomial time algorithm to find such an optimal solution. If the number of vertices is even, the optimal value lies between 0 and 2p and these two bounds are tight, which can be shown by an analytic solution for a regular n-gon."],["dc.identifier.doi","10.1080/02331934.2016.1276905"],["dc.identifier.isi","000395170900005"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43539"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Taylor & Francis Ltd"],["dc.relation.issn","1029-4945"],["dc.relation.issn","0233-1934"],["dc.title","Minimization and maximization versions of the quadratic travelling salesman problem"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","929"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","European Journal of Operational Research"],["dc.bibliographiccitation.lastpage","944"],["dc.bibliographiccitation.volume","286"],["dc.contributor.author","Dahlbeck, Mirko"],["dc.contributor.author","Fischer, Anja"],["dc.contributor.author","Fischer, Frank"],["dc.date.accessioned","2021-04-14T08:32:04Z"],["dc.date.available","2021-04-14T08:32:04Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.ejor.2020.04.010"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83796"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","0377-2217"],["dc.title","Decorous combinatorial lower bounds for row layout problems"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","891"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Combinatorial Optimization"],["dc.bibliographiccitation.lastpage","915"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Fischer, Anja"],["dc.contributor.author","Hungerländer, Philipp"],["dc.date.accessioned","2020-12-10T14:11:40Z"],["dc.date.available","2020-12-10T14:11:40Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s10878-017-0119-z"],["dc.identifier.eissn","1573-2886"],["dc.identifier.issn","1382-6905"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71156"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The traveling salesman problem on grids with forbidden neighborhoods"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","417"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Mathematical Programming"],["dc.bibliographiccitation.lastpage","446"],["dc.bibliographiccitation.volume","169"],["dc.contributor.author","Fischer, Anja"],["dc.contributor.author","Fischer, Frank"],["dc.contributor.author","McCormick, S. Thomas"],["dc.date.accessioned","2020-12-10T14:11:10Z"],["dc.date.available","2020-12-10T14:11:10Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s10107-017-1140-9"],["dc.identifier.eissn","1436-4646"],["dc.identifier.issn","0025-5610"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70990"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Matroid optimisation problems with nested non-linear monomials in the objective function"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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