Now showing 1 - 10 of 10
  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","107"],["dc.bibliographiccitation.issue","02"],["dc.bibliographiccitation.journal","The Thoracic and Cardiovascular Surgeon"],["dc.bibliographiccitation.lastpage","113"],["dc.bibliographiccitation.volume","68"],["dc.contributor.author","Saha, Shekhar"],["dc.contributor.author","Varghese, Sam"],["dc.contributor.author","Ahmad, Ammar Al"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Waezi, Narges"],["dc.contributor.author","Niehaus, Heidi"],["dc.contributor.author","Baraki, Hassina"],["dc.contributor.author","Kutschka, Ingo"],["dc.date.accessioned","2020-12-10T18:12:17Z"],["dc.date.available","2020-12-10T18:12:17Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1055/s-0038-1670663"],["dc.identifier.eissn","1439-1902"],["dc.identifier.issn","0171-6425"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74313"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Complex Valve Surgery in Elderly Patients: Increasingly Necessary and Surprisingly Feasible"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article Discussion
    [["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","The Annals of Thoracic Surgery"],["dc.bibliographiccitation.volume","95"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Popov, Aron Frederik"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Stojanovic, Tomislav"],["dc.date.accessioned","2018-11-07T09:27:47Z"],["dc.date.available","2018-11-07T09:27:47Z"],["dc.date.issued","2013"],["dc.format.extent","E73"],["dc.identifier.doi","10.1016/j.athoracsur.2012.09.077"],["dc.identifier.isi","000315332800008"],["dc.identifier.pmid","23438570"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30616"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0003-4975"],["dc.title","Reconstruction of Extrapericardial Rupture of Inferior Vena Cava Without Cardiopulmonary Bypass Due to Blunt Trauma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.artnumber","e2694"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","PLoS Neglected Tropical Diseases"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Schleicher, Ulrike"],["dc.contributor.author","Steiner, Reto"],["dc.contributor.author","Wentker, Pia"],["dc.contributor.author","Mahfuz, Farouq"],["dc.contributor.author","Stahl, Hans-Christian"],["dc.contributor.author","Amin, Faquir Mohammad"],["dc.contributor.author","Bogdan, Christian"],["dc.contributor.author","Stahl, Kurt-Wilhelm"],["dc.date.accessioned","2018-11-07T09:44:04Z"],["dc.date.available","2018-11-07T09:44:04Z"],["dc.date.issued","2014"],["dc.description.abstract","Background Anthroponotic cutaneous leishmaniasis (CL) due to Leishmania (L.) tropica infection is a chronic, frequently disfiguring skin disease with limited therapeutic options. In endemic countries healing of ulcerative lesions is often delayed by bacterial and/or fungal infections. Here, we studied a novel therapeutic concept to prevent superinfections, accelerate wound closure, and improve the cosmetic outcome of ACL. Methodology/Principal Findings From 2004 to 2008 we performed a two-armed, randomized, double-blinded, phase IIa trial in Kabul, Afghanistan, with patients suffering from L. tropica CL. The skin lesions were treated with bipolar high-frequency electrocauterization (EC) followed by daily moist-wound-treatment (MWT) with polyacrylate hydrogel with (group I) or without (group II) pharmaceutical sodium chlorite (DAC N-055). Patients below age 5, with facial lesions, pregnancy, or serious comorbidities were excluded. The primary, photodocumented outcome was the time needed for complete lesion epithelialization. Biopsies for parasitological and (immuno)histopathological analyses were taken prior to EC (1(st)), after wound closure (2(nd)) and after 6 months (3(rd)). The mean duration for complete wound closure was short and indifferent in group I (59 patients, 43.1 d) and II (54 patients, 42 d; p=0.83). In patients with Leishmania-positive 2(nd) biopsies DAC N-055 caused a more rapid wound epithelialization (37.2 d vs. 58.3 d; p=0.08). Superinfections occurred in both groups at the same rate (8.8%). Except for one patient, reulcerations (10.2% in group I, 18.5% in group II; p=0.158) were confined to cases with persistent high parasite loads after healing. In vitro, DAC N-055 showed a leishmanicidal effect on pro- and amastigotes. Conclusions/Significance Compared to previous results with intralesional antimony injections, the EC plus MWT protocol led to more rapid wound closure. The tentatively lower rate of relapses and the acceleration of wound closure in a subgroup of patients with parasite persistence warrant future studies on the activity of DAC N-055. Trial Registration ClinicalTrails.gov NCT00947362 Author Summary In many countries of the Middle East such as Afghanistan, cutaneous leishmaniasis is a highly prevalent, chronic and stigmatizing skin disease. Poor hygiene conditions frequently aggravate the lesions due to bacterial and fungal superinfections. Classical treatments with injections of pentavalent antimony are hampered by costs, side effects, resistance development, supply and manufactural quality problems. In the present study on Afghan patients with Leishmania tropica-induced skin lesions we evaluated the clinical effect of an initial removal of lesion tissue by electrocoagulation using a bipolar high-frequency electrosurgery instrument, followed by daily moist wound treatment with or without a preparation of pharmaceutical sodium chlorite (DAC N-055). DAC N-055 is a compound with anti-infective, immunomodulatory and tissue repair-promoting effects. Our analysis revealed that the carefully performed moist wound treatment led to a rapid healing of the wounds within an average period of 6 weeks, even in the absence of the sodium chlorite preparation. This is considerably faster than the time spans previously reported for local or systemic antimony treatment. We believe that the current standard for local care of chronic wounds should also be applied to Leishmania skin lesions. If combined with an initial single high-frequency electrocoagulation, it is a highly effective, inexpensive and well-tolerated treatment option for cutaneous leishmaniasis."],["dc.identifier.doi","10.1371/journal.pntd.0002694"],["dc.identifier.isi","000332017500027"],["dc.identifier.pmid","24551257"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34314"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1935-2735"],["dc.title","Rapid Healing of Cutaneous Leishmaniasis by High-Frequency Electrocauterization and Hydrogel Wound Care with or without DAC N-055: A Randomized Controlled Phase IIa Trial in Kabul"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article Discussion
    [["dc.bibliographiccitation.firstpage","1841"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","The Annals of Thoracic Surgery"],["dc.bibliographiccitation.lastpage","1843"],["dc.bibliographiccitation.volume","98"],["dc.contributor.author","Emmert, Alexander"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Schmidt, Karsten"],["dc.contributor.author","Hinterthaner, Marc"],["dc.contributor.author","Bohnenberger, Hanibal"],["dc.contributor.author","Bähr, Mathias"],["dc.contributor.author","Schoendube, Friedrich A."],["dc.contributor.author","Danner, Bernhard C."],["dc.date.accessioned","2017-09-07T11:45:25Z"],["dc.date.available","2017-09-07T11:45:25Z"],["dc.date.issued","2014"],["dc.description.abstract","This clinical report deals with a giant true pulmonary venous aneurysm, which was partially thrombosed. The overall incidence of pulmonary venous aneurysms is unknown, and they are reported only occasionally. We present the case of a previously healthy man with acute onset of ischemic cerebral stroke. The cause was a thrombus in a huge aneurysm of the left superior pulmonary vein. The patient subsequently underwent uncomplicated therapy for stroke, including thrombolysis followed by excision of the giant pulmonary venous aneurysm. As curative therapy we recommend complete resection of this rare entity. (C) 2014 by The Society of Thoracic Surgeons"],["dc.identifier.doi","10.1016/j.athoracsur.2013.12.087"],["dc.identifier.gro","3142027"],["dc.identifier.isi","000344746600085"],["dc.identifier.pmid","25441803"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3734"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Science Inc"],["dc.relation.eissn","1552-6259"],["dc.relation.issn","0003-4975"],["dc.title","Aneurysm of the Pulmonary Vein: An Unusual Cause of Stroke"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]
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  • 2012Journal Article
    [["dc.bibliographiccitation.firstpage","e95"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Pacing and Clinical Electrophysiology"],["dc.bibliographiccitation.lastpage","e97"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Rajaruthnam, Direndra"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T09:11:38Z"],["dc.date.available","2018-11-07T09:11:38Z"],["dc.date.issued","2012"],["dc.description.abstract","We describe a case of 83-year-old man who was admitted to our department for treatment of recurrent device-pocket infections. Our report shows that in a case of high-risk patient with a complicated cardiac implantable electric devices infection involving multidrug-resistent gram-positive pathogen, the application of daptomycin in combination with staged surgical therapy can be efficient and safe."],["dc.identifier.doi","10.1111/j.1540-8159.2011.03163.x"],["dc.identifier.isi","000302540300009"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26763"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0147-8389"],["dc.title","Treatment of Cardiovascular Implantable Electronic Device Infection with Daptomycin"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","H533"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","American Journal of Physiology - Heart and Circulatory Physiology"],["dc.bibliographiccitation.lastpage","H541"],["dc.bibliographiccitation.volume","305"],["dc.contributor.author","Didie, Michael"],["dc.contributor.author","Biermann, Daniel"],["dc.contributor.author","Buchert, Ralph"],["dc.contributor.author","Hess, Andreas"],["dc.contributor.author","Wittkoepper, Katrin"],["dc.contributor.author","Christalla, Peter"],["dc.contributor.author","Doeker, Stephan"],["dc.contributor.author","Jebran, Fawad"],["dc.contributor.author","Schoendube, Friedrich"],["dc.contributor.author","Reichenspurner, Hermann"],["dc.contributor.author","El-Armouche, Ali"],["dc.contributor.author","Zimmermann, Wolfram-Hubertus"],["dc.date.accessioned","2017-09-07T11:47:38Z"],["dc.date.available","2017-09-07T11:47:38Z"],["dc.date.issued","2013"],["dc.description.abstract","Total mechanical unloading of the heart in classical models of heterotopic heart transplantation leads to cardiac atrophy and functional deterioration. In contrast, partial unloading of failing human hearts with left ventricular (LV) assist devices (LVADs) can in some patients ameliorate heart failure symptoms. Here we tested in heterotopic rat heart transplant models whether partial volume-loading (VL; anastomoses: aorta of donor to aorta of recipient, pulmonary artery of donor to left atrium of donor, superior vena cava of donor to inferior vena cava of recipient; n = 27) is superior to the classical model of myocardial unloading (UL; anastomoses: aorta of donor to aorta of recipient, pulmonary artery of donor to inferior vena cava of recipient; n = 14) with respect to preservation of ventricular morphology and function. Echocardiography, magnetic resonance imaging, and LV-pressure-volume catheter revealed attenuated myocardial atrophy with similar to 30% higher LV weight and better systolic contractile function in VL compared with UL (fractional area shortening, 34% vs. 18%; maximal change in pressure over time, 2,986 +/- 252 vs. 2,032 +/- 193 mmHg/s). Interestingly, no differences in fibrosis (Picrosirus red staining) or glucose metabolism (2-[18F]-fluoro-2-deoxy-D-glucose-PET) between VL and UL were observed. We conclude that the rat model of partial VL attenuates atrophic remodelling and shows superior morphological as well as functional preservation, and thus should be considered more widely as a research model."],["dc.identifier.doi","10.1152/ajpheart.00218.2013"],["dc.identifier.gro","3142311"],["dc.identifier.isi","000323549500009"],["dc.identifier.pmid","23771692"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/6875"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/11"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | A02: Bedeutung des Phosphatase-Inhibitors-1 fĂĽr die SR-spezifische Modulation der Beta- adrenozeptor-Signalkaskade"],["dc.relation","SFB 1002 | C04: Fibroblasten-Kardiomyozyten Interaktion im gesunden und erkrankten Herzen: Mechanismen und therapeutische Interventionen bei Kardiofibroblastopathien"],["dc.relation.issn","0363-6135"],["dc.relation.workinggroup","RG El-Armouche"],["dc.relation.workinggroup","RG Zimmermann (Engineered Human Myocardium)"],["dc.title","Preservation of left ventricular function and morphology in volume-loaded versus volume-unloaded heterotopic heart transplants"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","1434"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic and Vascular Anesthesia"],["dc.bibliographiccitation.lastpage","1438"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Saha, Shekhar"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Leistner, Marcus"],["dc.contributor.author","Kutschka, Ingo"],["dc.contributor.author","Niehaus, Heidi"],["dc.date.accessioned","2020-12-10T18:11:59Z"],["dc.date.available","2020-12-10T18:11:59Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1053/j.jvca.2019.10.055"],["dc.identifier.issn","1053-0770"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74207"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Turning Things Around: The Role of Prone Positioning in the Management of Acute Respiratory Failure After Cardiac Surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","409"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Interactive Cardiovascular and Thoracic Surgery"],["dc.bibliographiccitation.lastpage","415"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Jebran, Ahmad-Fawad"],["dc.contributor.author","Saha, Shekhar"],["dc.contributor.author","Waezi, Narges"],["dc.contributor.author","Al-Ahmad, Ammar"],["dc.contributor.author","Niehaus, Heidi"],["dc.contributor.author","Danner, Bernhard C."],["dc.contributor.author","Baraki, Hassina"],["dc.contributor.author","Kutschka, Ingo"],["dc.date.accessioned","2020-12-10T18:19:16Z"],["dc.date.available","2020-12-10T18:19:16Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1093/icvts/ivz112"],["dc.identifier.eissn","1569-9285"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75185"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Design and training effects of a physical reality simulator for minimally invasive mitral valve surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","42"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Interactive Cardiovascular and Thoracic Surgery"],["dc.bibliographiccitation.lastpage","47"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Saha, Shekhar"],["dc.contributor.author","Hofmann, Sandra"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Waezi, Narges"],["dc.contributor.author","Kutschka, Ingo"],["dc.contributor.author","Friedrich, Martin G"],["dc.contributor.author","Niehaus, Heidi"],["dc.date.accessioned","2021-04-14T08:25:33Z"],["dc.date.available","2021-04-14T08:25:33Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1093/icvts/ivaa049"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81664"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1569-9285"],["dc.title","Safety and efficacy of digital chest drainage units compared to conventional chest drainage units in cardiac surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.journal","The Thoracic and Cardiovascular Surgeon"],["dc.contributor.author","Saha, Shekhar"],["dc.contributor.author","Karaca, KĂĽbra"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Waezi, Narges"],["dc.contributor.author","Ort, Katharina"],["dc.contributor.author","Brandes, Ivo"],["dc.contributor.author","Hagl, Christian"],["dc.contributor.author","Niehaus, Heidi"],["dc.date.accessioned","2021-04-14T08:26:09Z"],["dc.date.available","2021-04-14T08:26:09Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1055/s-0040-1716897"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81853"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1439-1902"],["dc.relation.issn","0171-6425"],["dc.title","Diagnostic Value of Cholinesterase Activity for the Development of Postoperative Delirium after Cardiac Surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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