Now showing 1 - 8 of 8
  • 2012Journal Article
    [["dc.bibliographiccitation.artnumber","39"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Hinz, Jose"],["dc.contributor.author","Gehoff, Philipp"],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","Hosseini, Morteza Tavakkoli"],["dc.contributor.author","Didilis, Vassilios N."],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Gehoff, Anastasia"],["dc.contributor.author","Wiese, Christoph Hermann"],["dc.contributor.author","Schulz, Egbert Godehard"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Popov, Aron Frederik"],["dc.date.accessioned","2018-11-07T09:11:03Z"],["dc.date.available","2018-11-07T09:11:03Z"],["dc.date.issued","2012"],["dc.description.abstract","Background: Peri-operative statin therapy in cardiac surgery cases is reported to reduce the rate of mortality, stroke, postoperative atrial fibrillation, and systemic inflammation. Systemic inflammation could affect the hemodynamic parameters and stability. We set out to study the effect of statin therapy on perioperative hemodynamic parameters and its clinical outcome. Methods: In a single center study from 2006 to 2007, peri-operative hemodynamic parameters of 478 patients, who underwent cardiac surgery with cardiopulmonary bypass, were measured. Patients were divided into those who received perioperative statin therapy (n = 276; statin group) and those who did not receive statin therapy (n = 202; no-statin group). The two groups were compared together using Kolmogorov-Smirnov-Test, Fisher's-Exact-Test, and Student's-T-test. A p value < 0.05 was considered as significant. Results: There was no significant difference in the preoperative risk factors. Onset of postoperative atrial fibrillation was not affected by statin therapy. Extended hemodynamic measurements revealed no significant difference between the two groups, apart from Systemic Vascular Resistance Index (SVRI). The no-statin group had a significantly higher SVRI (882 +/- 206 vs. 1050 +/- 501 dyn s/cm(5)/m(2), p = 0.022). Inotropic support was the same in both groups and no significant difference in the mortality rate was noticed. Also, hemodynamic parameters were not affected by different types and doses of statins. Conclusions: Perioperative statin therapy for patients undergoing on-pump coronary bypass grafting or valvular surgery, does not affect the hemodynamic parameters and its clinical outcome."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2012"],["dc.identifier.doi","10.1186/1749-8090-7-39"],["dc.identifier.isi","000306370800001"],["dc.identifier.pmid","22533985"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8510"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26638"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Hemodynamic effects of peri-operative statin therapy in on-pump cardiac surgery patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.artnumber","14"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Grossmann, Marius"],["dc.contributor.author","Unsoeld, Bernhard W."],["dc.contributor.author","Wachter, R. Rolf"],["dc.contributor.author","Perl, Thorsten"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Popov, Aron Frederik"],["dc.date.accessioned","2018-11-07T10:01:53Z"],["dc.date.available","2018-11-07T10:01:53Z"],["dc.date.issued","2015"],["dc.description.abstract","Giant-cell myocarditis (GCM) is known as a rare, rapidly progressive, and frequently fatal myocardial disease in young and middle-aged adults. We report about a 76 year old male patient who underwent implantation with a biventricular Berlin Heart Excor system at the age of 74 due to acute biventricular heart failure caused by giant-cell myocarditis. The implantation was without any surgical problems; however, a difficulty was the immunosuppressive therapy after implantation. Meanwhile the patient is 76 years old and lives with circulatory support for about 3 years without major adverse events. Also, in terms of mobility in old age there are no major limitations. It seems that in even selected elderly patients an implantation of a long term support with the biventricular Berlin Heart Excor is a useful therapeutic option with an acceptable outcome."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2015"],["dc.identifier.doi","10.1186/s13019-015-0218-9"],["dc.identifier.isi","000350433300001"],["dc.identifier.pmid","25637129"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13464"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38121"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Long term biventricular support with Berlin Heart Excor in a Septuagenarian with giant-cell myocarditis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","502"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Vascular and Endovascular Surgery"],["dc.bibliographiccitation.lastpage","506"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Danner, Bernhard Christoph"],["dc.contributor.author","Bougioukas, Ioannis"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Stojanovic, Tomislav"],["dc.date.accessioned","2018-11-07T09:19:26Z"],["dc.date.available","2018-11-07T09:19:26Z"],["dc.date.issued","2013"],["dc.description.abstract","Objective: We conducted a retrospective study to compare short- and mid-term patencies of Viabahn with surgical above-knee prosthetic bypass (pAKB). Methods: The records of 52 patients with either pAKB (n = 25) or Viabahn (n = 27) were reviewed. The majority had Rutherford clinical grade 3. Patients were followed after 3, 6, and 12 months and yearly thereafter. Results: For Viabahn, the short-term (1-16 months) primary patency rate was 60% with a secondary patency rate of 90%, and mid-term (1-68 months) patencies of 47% and 83.3%, respectively. In pAKB, the short-term results revealed a primary patency rate of 78% with a secondary patency of 91% and mid-term results of 65% and 90%, respectively. No statistical difference was found concerning short-term patencies. Mid-term primary patency was lower for Viabahn (P < .05) and secondary patency proved no significant difference. Conclusion: Viabahn revealed similar short-term primary and secondary patencies but lower mid-term primary patency. It provides a good alternative therapy to pAKB."],["dc.identifier.doi","10.1177/1538574413495964"],["dc.identifier.isi","000324591400002"],["dc.identifier.pmid","23867203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28635"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Inc"],["dc.relation.issn","1938-9116"],["dc.relation.issn","1538-5744"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Is There an Alternative to the Surgical Above-Knee Bypass in Treatment of Superficial Femoral Artery Disease? Experiences With Viabahn Stent Graft"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017-01-25Journal Article
    [["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Bougioukas, Ioannis"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Grossmann, Marius"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Schoendube, Friedrich A."],["dc.contributor.author","Danner, Bernhard Christoph"],["dc.date.accessioned","2018-10-10T09:54:39Z"],["dc.date.available","2018-10-10T09:54:39Z"],["dc.date.issued","2017-01-25"],["dc.description.abstract","Re-exploration for bleeding accounts for increased morbidity and mortality after major cardiac operations. The use of temporary epicardial pacemaker wires is a common procedure at many departments. The removal of these wires postoperatively can potentially lead to a serious bleeding necessitating intervention. From Jan 2011 till Dec 2015 a total of 4244 major cardiac procedures were carried out at our department. We used temporary epicardial pacemaker wires in all cases. We collected all re-explorations for bleeding and pericardial tamponade from our surgical database and then we focused on the late re-explorations, meaning on the 4th postoperative day and thereafter, trying to identify the removal of the temporary pacemakerwires as the definite cause of bleeding. Patients’ records and medication were examined. Thirty-nine late re-explorations for bleeding, consisting of repeat sternotomies, thoracotomies and subxiphoid pericardial drainages, were gathered. Eight patients had an acute bleeding incidence after removal ofthe temporary wires (0.18%). In four of these patients, a pericardial drainage was inserted, whereas the remaining patients were re-explorated through a repeat sternotomy. Two patients died of the acute pericardial tamponade,three had a blood transfusion and one had a wound infection. Seven out of eight patients were either on dualantiplatelet therapy or on combination of aspirin and vitamin K antagonist. A need for re-exploration due to removal of the temporary pacemaker wires is a very rare complication, which however increases morbidity and mortality. Adjustment of the postoperative anticoagulation therapy at the time of removal of the wires could further minimize or even prevent this serious complication."],["dc.identifier.doi","10.1186/s13019-017-0569-5"],["dc.identifier.gro","633982"],["dc.identifier.pmid","28122567"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14188"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15938"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.eissn","1749-8090"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Is there a correlation between late re-exploration after cardiac surgery and removal of epicardial pacemaker wires?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2011Journal Article
    [["dc.bibliographiccitation.artnumber","112"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Rajaruthnam, Direndra"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Hinz, Jose"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:51:42Z"],["dc.date.available","2018-11-07T08:51:42Z"],["dc.date.issued","2011"],["dc.description.abstract","The reported incidence of deep sternal wound infection (DSWI) after cardiac surgery is 0.4-5% with Staphylococcus aureus being the most common pathogen isolated from infected wound sternotomies and bacteraemic blood cultures. This infection is associated with a higher morbidity and mortality than other known aetiologies. Little is reported about the optimal antibiotic management. The aim of the study is to quantify the application of daptomycin treatment of DSWI due to gram-positive organisms post cardiac surgery. We performed an observational analysis in 23 cases of post sternotomy DSWI with gram-positive organisms February 2009 and September 2010. When the wound appeared viable and the microbiological cultures were negative, the technique of chest closure was individualised to the patient. The incidence of DSWI was 1.46%. The mean dose of daptomycin application was 4.4 +/- 0.9 mg/kg/d and the average duration of the daptomycin application was 14.47 +/- 7.33 days. In 89% of the patients VAC therapy was used. The duration from daptomycin application to sternal closure was 18 +/- 13.9 days. The parameters of infection including, fibrinogen (p = 0.03), white blood cell count (p = 0.001) and C-reactive protein (p = 0.0001) were significantly reduced after daptomycin application. We had no mortality and wound healing was successfully achieved in all patients. Treatment of DSWI due to gram-positive organisms with a daptomycin-containing antibiotic regimen is safe, effective and promotes immediate improvement of local wound conditions. Based on these observations, daptomycin may offer a new treatment option for expediting surgical management of DSWI after cardiac surgery."],["dc.identifier.doi","10.1186/1749-8090-6-112"],["dc.identifier.isi","000295483400002"],["dc.identifier.pmid","21929771"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6983"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21999"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Treatment of gram-positive deep sternal wound infections in cardiac surgery -experiences with daptomycin-"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article Discussion
    [["dc.bibliographiccitation.artnumber","21"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Ort, Katharina R."],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Danner, Bernhard Christoph"],["dc.contributor.author","Bougioukas, Ioannis"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.date.accessioned","2018-11-07T09:29:01Z"],["dc.date.available","2018-11-07T09:29:01Z"],["dc.date.issued","2013"],["dc.description.abstract","Daptomycin in combination with surgical therapy has shown to be effective for treatment of deep sternal wound infection in cardiac surgery. However, till now midterm results in terms of re-infection or re-operation in patients who were successfully treated with daptomycin for gram-positive deep sternal wound infection are not published. Herein, we present midterm results in patients treated successfully with daptomycin after cardiac surgery."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2013"],["dc.identifier.doi","10.1186/1749-8090-8-21"],["dc.identifier.isi","000315669900001"],["dc.identifier.pmid","23351310"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8635"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30922"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Midterm results after treatment of gram-positive deep sternal wound infections with daptomycin for cardiac surgery patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","e12449"],["dc.bibliographiccitation.issue","40"],["dc.bibliographiccitation.journal","Medicine"],["dc.bibliographiccitation.volume","97"],["dc.contributor.author","Waezi, Narges"],["dc.contributor.author","Saha, Shekhar"],["dc.contributor.author","Bougioukas, Ioannis"],["dc.contributor.author","Emmert, Alexander"],["dc.contributor.author","Danner, Bernhard Christoph"],["dc.contributor.author","Baraki, Hassina"],["dc.contributor.author","Kutschka, Ingo"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Stojanovic, Tomislav"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.date.accessioned","2020-12-10T18:20:04Z"],["dc.date.available","2020-12-10T18:20:04Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1097/MD.0000000000012449"],["dc.identifier.issn","0025-7974"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15374"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75455"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Viabahn stent graft compared with prosthetic surgical above-knee bypass in treatment of superficial femoral artery disease"],["dc.title.alternative","Long-term results of a retrospective analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.artnumber","73"],["dc.bibliographiccitation.journal","BMC Nephrology"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Friedrich, Martin G."],["dc.contributor.author","Bougioukas, Ioannis"],["dc.contributor.author","Kolle, Johanna"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Placzek, Marius"],["dc.contributor.author","Tirilomis, Theodor"],["dc.date.accessioned","2018-11-07T10:27:14Z"],["dc.date.available","2018-11-07T10:27:14Z"],["dc.date.issued","2017"],["dc.description.abstract","Background: Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGAL) is a predictive biomarker of acute kidney injury and may increase after cardiopulmonary bypass (CPB). However, time correlation of NGAL expression and severity of renal injury is still unclear. The aim of our study was to investigate CPB-related urine NGAL (uNGAL) secretion in correlation to postoperative renal function. Methods: Data of NGAL expression along with clinical data of 81 patients (52 male and 29 female) were included in this study. Mean age of the patients was 66.8 +/- 12.8 years. Urine NGAL was measured at seven time points (T-0: baseline; T-1: start CPB, T-2: 40 min on CPB; T-3: 80 min on CPB; T-4: 120 min on CPB; T-p1: 15 min after CPB; T-p2: 4 h after admission to the intensive care unit) and renal function in the postoperative period was classified daily according to Acute Kidney Injury Network (Ronco et al, Int J Artif Organs 30(5): 373-6) criteria (AKIN). Results: Expression of uNGAL increased at T-4 (120 min on CPB) and post-CPB (T-p1 and T-p2; p < 0.01 vs. baseline) but there was no correlation between uNGAL level and duration of CPB nor between uNGAL expression and occurrence of postoperative kidney injury. The renal function over 10 days after surgery remained normal in 50 patients (AKIN level 0), 18 patients (22%) developed mild and insignificant renal injury (AKIN level 1), eight patients (10%) developed moderate renal failure (AKIN level 2), and five patients (6%) severe kidney failure (AKIN level 3). Twenty-four out of 31 patients developed renal failure within the first 48 h after surgery. However, there was no correlation between uNGAL expression and severity of acute renal failure. Conclusion: Although uNGAL expression increased after CPB, the peak values neither predict acute postoperative kidney injury, nor severity of the injury."],["dc.identifier.doi","10.1186/s12882-017-0479-8"],["dc.identifier.isi","000397681200001"],["dc.identifier.pmid","28222690"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14308"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43208"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1471-2369"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","NGAL expression during cardiopulmonary bypass does not predict severity of postoperative acute kidney injury"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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