Schröder, Bernd

[["dc.bibliographiccitation.firstpage","66"],["dc.bibliographiccitation.lastpage","67"],["dc.contributor.author","Lindig, Carola"],["dc.contributor.author","Abel, Hansjörg"],["dc.contributor.author","Isselstein, Johannes"],["dc.contributor.author","Schröder, Bernd"],["dc.contributor.author","Riede, Susanne"],["dc.contributor.author","Breves, Gerhard"],["dc.date.accessioned","2017-09-07T11:51:44Z"],["dc.date.available","2017-09-07T11:51:44Z"],["dc.date.issued","2013"],["dc.identifier.gro","3148018"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/5358"],["dc.language.iso","de"],["dc.notes.status","fcwi"],["dc.notes.submitter","chake"],["dc.relation.conference","KLIFF-Tagung \"Vom globalen Klimawandel zu regionalen Anpassungsstrategien\""],["dc.relation.eventend","2013-09-03"],["dc.relation.eventlocation","Göttingen"],["dc.relation.eventstart","2013-09-02"],["dc.relation.ispartof","Vom globalen Klimawandel zu regionalen Anpassungsstrategien"],["dc.title","Wechselwirkungen zwischen Leguminosenart und Trockenstress auf Nährstoffzusammensetzung, mikrobiellen Abbau und Fermentationsparameter von verschiedenen Leguminosenarten in vitro"],["dc.type","conference_abstract"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","161"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY"],["dc.bibliographiccitation.lastpage","169"],["dc.bibliographiccitation.volume","163"],["dc.contributor.author","Herrmann, Jens"],["dc.contributor.author","Schroeder, Bernd"],["dc.contributor.author","Klinger, Stefanie"],["dc.contributor.author","Thorenz, Anja"],["dc.contributor.author","Werner, Ann-Cathrin"],["dc.contributor.author","Abel, Hansjoerg"],["dc.contributor.author","Breves, Gerhard"],["dc.date.accessioned","2018-11-07T09:07:01Z"],["dc.date.available","2018-11-07T09:07:01Z"],["dc.date.issued","2012"],["dc.description.abstract","It has been shown in several species that the intestinal Na+-dependent glucose co-transporter 1 (SGLT1) is more abundant in the jejunum than in ileum. In contrast, the efficiency of intestinal glucose uptake rates in suckling piglets or weaned pigs is not clearly fitting with this segmental distribution. The aim of this study was to evaluate SGLT1 mediated glucose absorption in the jejunum and ileum of growing pigs (Sus scrofa) in more detail. In Ussing chambers, basal short-circuit currents were significantly more positive in the jejunum. It could be demonstrated that the electrogenic ileal glucose transport was significantly more pronounced in different breeds and occurred at 5 mmol.L-1 glucose 7 times faster in the ileum, although slightly higher jejunal expression of glycosylated SGLT1 was detected by Western blotting. This expression pattern was connected to significantly lower phlorizin sensitivity in the jejunum. As the more efficient ileal glucose absorption was also observable with glucose uptake studies into isolated brush-border membrane vesicles without differences in abundance and activity of the Na+/K+-ATPase in both segments, we conclude that the segmental differences in porcine glucose transport characteristics may be based on direct or indirect modulations of SGLT1 activity. (C) 2012 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.cbpa.2012.05.204"],["dc.identifier.isi","000306634400020"],["dc.identifier.pmid","22683689"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25691"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1095-6433"],["dc.title","Segmental diversity of electrogenic glucose transport characteristics in the small intestines of weaned pigs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","371"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","ARCHIVES OF ANIMAL NUTRITION-ARCHIV FUR TIERERNAHRUNG"],["dc.bibliographiccitation.lastpage","377"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Breves, Gerhard"],["dc.contributor.author","Zitnan, R."],["dc.contributor.author","Schroder, B."],["dc.contributor.author","Winckler, Christoph"],["dc.contributor.author","Hagemeister, H."],["dc.contributor.author","Failing, K."],["dc.contributor.author","Voigt, J."],["dc.date.accessioned","2018-11-07T09:57:19Z"],["dc.date.available","2018-11-07T09:57:19Z"],["dc.date.issued","2002"],["dc.description.abstract","In a previous study we found a positive correlation between early weaning in calves and morphological parameters which were indicative of ruminal development, i.e. the length and width of the papillae. The objective of the present study was to determine to what extent this observation could be reflected by modulations of absorptive and secretory functions of the rumen mucosa. For this purpose the short-circuit currents (I-sc) as a measure of electrogenic net ion fluxes and the transepithelial conductances (G(T)) as a measure of the overall tissue permeability were measured in vitro applying the Ussing-chamber technique. Simultaneously, the unidirectional flux rates of sodium and chloride across rumen wall epithelia were determined in the absence of electrochemical gradients. Under these conditions, significant positive net flux rates (J(net)) clearly indicate active mechanisms for electrolyte absorption. For the experiments 12 male Holstein calves 7 d of age were assigned to three groups of 4 animals each: milk group (I, slaughtered after 6 weeks of age), late weaning group (II, slaughtered after 9 weeks of age) and early weaning group (II, weaned after 6 weeks of age and slaughtered after 9 weeks of age). Whereas G(T) values remained unaffected by different age and feeding, I-sc values were significantly affected by early weaning but were not influenced by age. Irrespective of weaning time active absorption of Na+ tended to be higher by about 60% in 9 weeks old animals. Active absorption of chloride was significantly increased in milk fed 9 weeke old calves and this effect was further stimulated by early weaning. In conclusion, the data show an increasing active Na+ absorption with age in calf rumen that could not be influenced by early weaning. Similarly, active Cl- absorption was initially increased during postnatal development and this effect could be stimulated further by early weaning."],["dc.identifier.doi","10.1080/00039420215630"],["dc.identifier.isi","000180574600006"],["dc.identifier.pmid","12556048"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37132"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0003-942X"],["dc.title","Research note: Postnatal development of electrolyte transport in calf rumen as affected by weaning time"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","911"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Zeitschrift für Gastroenterologie"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Bender, A."],["dc.contributor.author","Breves, Gerhard"],["dc.contributor.author","Stein, J."],["dc.contributor.author","Leonhard-Marek, S."],["dc.contributor.author","Schroder, B."],["dc.contributor.author","Winckler, Christoph"],["dc.date.accessioned","2018-11-07T08:31:18Z"],["dc.date.available","2018-11-07T08:31:18Z"],["dc.date.issued","2001"],["dc.description.abstract","Antimicrobial substances such as vancomycin or metronidazole suppress normal gut flora, thereby preventing physiological fermentation of colonic substrates that may promote mucosal inflammation. This study was designed to establish an in vitro model of microbial metabolism in the colon under control and disturbed conditions (acidic PH) to investigate specific effects of vancomycin and metronidazole on the production of short chain fatty acids (SCFA), which play a pivotal role in maintaining homeostasis in the colon. The experiments were carried out with the colon simulation technique (Cositec) representing an in vitro model for the semi-continuous incubation of defined colon contents. Inocula and fermentable substrates were sampled from cecal contents of fistulated pigs. Disturbed microbial metabolism was generated by reduction of pH in the fermentation vessels from 6.7 to 5.8 and 5.1. in general, application of either vancomycin or metronidazole resulted in a significant decrease of SCFA production rates indicating substantial disturbance of the homeostasis of microbial metabolism. With low doses of vancomycin acetate and butyrate production rates were reduced and with high doses of the antibiotic propionate production was inhibited to a greater extent. Treatment with metronidazole inhibited butyrate production almost completely. Similarly, low pH caused a reduction in total SCFA production, which was mainly due to respective decrease of acetate synthesis. Metronidazole effects were not consistently changed at low PH. The Cositec system provides an excellent facility to test the effects of different antibiotics under defined conditions. In this study, both vancomycin and metronidazole affected microbial metabolism to a considerable extent. Both substances may thus be responsible for disturbances of colon function in vivo."],["dc.identifier.doi","10.1055/s-2001-18537"],["dc.identifier.isi","000172608900001"],["dc.identifier.pmid","11778150"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17093"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Demeter Verlag Georg Thieme Verlag"],["dc.relation.issn","0044-2771"],["dc.title","Colonic fermentation as affected by antibiotics and acidic pH: Application of an in vitro model"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]