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Maier, Ilko L.
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Maier, Ilko L.
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Maier, Ilko L.
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Maier, I. L.
Maier, Ilko
Maier, I.
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2018Journal Article [["dc.bibliographiccitation.firstpage","372"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","International Journal of Stroke"],["dc.bibliographiccitation.lastpage","380"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Alegiani, Anna C"],["dc.contributor.author","Dorn, Franziska"],["dc.contributor.author","Herzberg, Moriz"],["dc.contributor.author","Wollenweber, Frank A"],["dc.contributor.author","Kellert, Lars"],["dc.contributor.author","Siebert, Eberhard"],["dc.contributor.author","Nolte, Christian H"],["dc.contributor.author","von Rennenberg, Regina"],["dc.contributor.author","Hattingen, Elke"],["dc.contributor.author","Petzold, Gabor C"],["dc.contributor.author","Bode, Felix J"],["dc.contributor.author","Pfeilschifter, Waltraud"],["dc.contributor.author","Schäfer, Jan H"],["dc.contributor.author","Wagner, Marlies"],["dc.contributor.author","Röther, Joachim"],["dc.contributor.author","Eckert, Bernd"],["dc.contributor.author","Kraft, Peter"],["dc.contributor.author","Pham, Mirko"],["dc.contributor.author","Boeckh-Behrens, Tobias"],["dc.contributor.author","Wunderlich, Silke"],["dc.contributor.author","Bernkopf, Kathleen"],["dc.contributor.author","Reich, Arno"],["dc.contributor.author","Wiesmann, Martin"],["dc.contributor.author","Mpotsaris, Anastasios"],["dc.contributor.author","Psychogios, Marios"],["dc.contributor.author","Liman, Jan"],["dc.contributor.author","Maier, Ilko"],["dc.contributor.author","Berrouschot, Jörg"],["dc.contributor.author","Bormann, Albrecht"],["dc.contributor.author","Limmroth, Volker"],["dc.contributor.author","Spreer, Joachim"],["dc.contributor.author","Petersen, Martina"],["dc.contributor.author","Krause, Lars"],["dc.contributor.author","Lowens, Stephan"],["dc.contributor.author","Kraemer, Christoffer"],["dc.contributor.author","Zweynert, Sarah"],["dc.contributor.author","Lange, Kristin S"],["dc.contributor.author","Thonke, Sven"],["dc.contributor.author","Kastrup, Andreas"],["dc.contributor.author","Papanagiotou, Panagiotis"],["dc.contributor.author","Alber, Burkhard"],["dc.contributor.author","Braun, Michael"],["dc.contributor.author","Fiehler, Jens"],["dc.contributor.author","Gerloff, Christian"],["dc.contributor.author","Dichgans, Martin"],["dc.contributor.author","Thomalla, Götz"],["dc.date.accessioned","2020-12-10T18:38:36Z"],["dc.date.available","2020-12-10T18:38:36Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1177/1747493018806199"],["dc.identifier.eissn","1747-4949"],["dc.identifier.issn","1747-4930"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77382"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2022Journal Article [["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Journal of Neurosurgery: Pediatrics"],["dc.bibliographiccitation.lastpage","7"],["dc.contributor.author","Lu, Victor M."],["dc.contributor.author","Luther, Evan M."],["dc.contributor.author","Silva, Michael A."],["dc.contributor.author","Elarjani, Turki"],["dc.contributor.author","Abdelsalam, Ahmed"],["dc.contributor.author","Maier, Ilko"],["dc.contributor.author","Al Kasab, Sami"],["dc.contributor.author","Jabbour, Pascal M."],["dc.contributor.author","Kim, Joon-Tae"],["dc.contributor.author","Wolfe, Stacey Q."],["dc.contributor.author","Starke, Robert M."],["dc.date.accessioned","2022-09-01T09:51:05Z"],["dc.date.available","2022-09-01T09:51:05Z"],["dc.date.issued","2022"],["dc.description.abstract","OBJECTIVE\n Although younger adults have been shown to have better functional outcomes after mechanical thrombectomy (MT) for acute ischemic stroke (AIS), the significance of this relationship in the adolescent and young adult (AYA) population is not well defined given its undefined rarity. Correspondingly, the goal of this study was to determine the prognostic significance of age in this specific demographic following MT for large-vessel occlusions.\n \n \n METHODS\n A prospectively maintained international multi-institutional database, STAR (Stroke Thrombectomy and Aneurysm Registry), was reviewed for all patients aged 12–18 (adolescent) and 19–25 (young adult) years. Parameters were compared using chi-square and t-test analyses, and associations were interrogated using regression analyses.\n \n \n RESULTS\n Of 7192 patients in the registry, 41 (0.6%) satisfied all criteria, with a mean age of 19.7 ± 3.3 years. The majority were male (59%) and young adults (61%) versus adolescents (39%). The median prestroke modified Rankin Scale (mRS) score was 0 (range 0–2). Strokes were most common in the anterior circulation (88%), with the middle cerebral artery being the most common vessel (59%). The mean onset-to–groin puncture and groin puncture–to-reperfusion times were 327 ± 229 and 52 ± 42 minutes, respectively. The mean number of passes was 2.2 ± 1.2, with 61% of the cohort achieving successful reperfusion. There were only 3 (7%) cases of reocclusion. The median mRS score at 90 days was 2 (range 0–6). Between the adolescent and young adult subgroups, the median mRS score at last follow-up was statistically lower in the adolescent subgroup (1 vs 2, p = 0.03), and older age was significantly associated with a higher mRS at 90 days (coefficient 0.33, p < 0.01).\n \n \n CONCLUSIONS\n Although rare, MT for AIS in the AYA demographic is both safe and effective. Even within this relatively young demographic, age remains significantly associated with improved functional outcomes. The implication of age-dependent stroke outcomes after MT within the AYA demographic needs greater validation to develop effective age-specific protocols for long-term care across both pediatric and adult centers."],["dc.identifier.doi","10.3171/2022.7.PEDS22250"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113878"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","1933-0715"],["dc.relation.issn","1933-0707"],["dc.title","Prognostic significance of age within the adolescent and young adult acute ischemic stroke population after mechanical thrombectomy: insights from STAR"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2018Journal Article [["dc.bibliographiccitation.firstpage","362"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Stroke"],["dc.bibliographiccitation.lastpage","372"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Schregel, Katharina"],["dc.contributor.author","Tsogkas, Ioannis"],["dc.contributor.author","Peter, Carolin"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Behme, Daniel"],["dc.contributor.author","Schnieder, Marlena"],["dc.contributor.author","Maier, Ilko L."],["dc.contributor.author","Liman, Jan"],["dc.contributor.author","Knauth, Michael"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.date.accessioned","2021-06-01T10:48:59Z"],["dc.date.available","2021-06-01T10:48:59Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.5853/jos.2018.00605"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86121"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","2287-6405"],["dc.relation.issn","2287-6391"],["dc.title","Outcome Prediction Using Perfusion Parameters and Collateral Scores of Multi-Phase and Single-Phase CT Angiography in Acute Stroke: Need for One, Two, Three, or Thirty Scans?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2022Journal Article [["dc.bibliographiccitation.artnumber","e2241291"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","JAMA Network Open"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Porto, Guilherme B. F."],["dc.contributor.author","Chen, Ching-Jen"],["dc.contributor.author","Al Kasab, Sami"],["dc.contributor.author","Essibayi, Muhammed Amir"],["dc.contributor.author","Almallouhi, Eyad"],["dc.contributor.author","Hubbard, Zachary"],["dc.contributor.author","Chalhoub, Reda"],["dc.contributor.author","Alawieh, Ali"],["dc.contributor.author","Maier, Ilko"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.contributor.author","Park, Min S."],["dc.contributor.authorgroup","Stroke Thrombectomy and Aneurysm Registry (STAR) Collaborators"],["dc.date.accessioned","2022-12-01T08:30:58Z"],["dc.date.available","2022-12-01T08:30:58Z"],["dc.date.issued","2022"],["dc.description.abstract","Importance\r\n There is substantial controversy with regards to the adequacy and use of noncontrast head computed tomography (NCCT) for late-window acute ischemic stroke in selecting candidates for mechanical thrombectomy.\r\n \r\n \r\n Objective\r\n To assess clinical outcomes of patients with acute ischemic stroke presenting in the late window who underwent mechanical thrombectomy stratified by NCCT admission in comparison with selection by CT perfusion (CTP) and diffusion-weighted imaging (DWI).\r\n \r\n \r\n Design, Setting, and Participants\r\n In this multicenter retrospective cohort study, prospectively maintained Stroke Thrombectomy and Aneurysm (STAR) database was used by selecting patients within the late window of acute ischemic stroke and emergent large vessel occlusion from 2013 to 2021. Patients were selected by NCCT, CTP, and DWI. Admission Alberta Stroke Program Early CT Score (ASPECTS) as well as confounding variables were adjusted. Follow-up duration was 90 days. Data were analyzed from November 2021 to March 2022.\r\n \r\n \r\n Exposures\r\n Selection by NCCT, CTP, or DWI.\r\n \r\n \r\n Main Outcomes and Measures\r\n Primary outcome was functional independence (modified Rankin scale 0-2) at 90 days.\r\n \r\n \r\n Results\r\n \r\n Among 3356 patients, 733 underwent late-window mechanical thrombectomy. The median (IQR) age was 69 (58-80) years, 392 (53.5%) were female, and 449 (65.1%) were White. A total of 419 were selected with NCCT, 280 with CTP, and 34 with DWI. Mean (IQR) admission ASPECTS were comparable among groups (NCCT, 8 [7-9]; CTP, 8 [7-9]; DWI 8, [7-9];\r\n P\r\n  = .37). There was no difference in the 90-day rate of functional independence (aOR, 1.00; 95% CI, 0.59-1.71;\r\n P\r\n  = .99) after adjusting for confounders. Symptomatic intracerebral hemorrhage (NCCT, 34 [8.6%]; CTP, 37 [13.5%]; DWI, 3 [9.1%];\r\n P\r\n  = .12) and mortality (NCCT, 78 [27.4%]; CTP, 38 [21.1%]; DWI, 7 [29.2%];\r\n P\r\n  = .29) were similar among groups.\r\n \r\n \r\n \r\n Conclusions and Relevance\r\n In this cohort study, comparable outcomes were observed in patients in the late window irrespective of neuroimaging selection criteria. Admission NCCT scan may triage emergent large vessel occlusion in the late window."],["dc.identifier.doi","10.1001/jamanetworkopen.2022.41291"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118031"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-621"],["dc.relation.eissn","2574-3805"],["dc.title","Association of Noncontrast Computed Tomography and Perfusion Modalities With Outcomes in Patients Undergoing Late-Window Stroke Thrombectomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2021Journal Article [["dc.bibliographiccitation.firstpage","10.1212/WNL.0000000000013049"],["dc.bibliographiccitation.journal","Neurology"],["dc.contributor.author","Katsanos, Aristeidis H"],["dc.contributor.author","Malhotra, Konark"],["dc.contributor.author","Ahmed, Niaz"],["dc.contributor.author","Seitidis, Georgios"],["dc.contributor.author","Mistry, Eva A."],["dc.contributor.author","Mavridis, Dimitris"],["dc.contributor.author","Kim, Joon-Tae"],["dc.contributor.author","Veroniki, Argie"],["dc.contributor.author","Maier, Ilko"],["dc.contributor.author","Matusevicius, Marius"],["dc.contributor.author","Tsivgoulis, Georgios"],["dc.date.accessioned","2021-12-01T09:23:05Z"],["dc.date.available","2021-12-01T09:23:05Z"],["dc.date.issued","2021"],["dc.description.abstract","Objective: To explore the association between blood pressure (BP) levels after endovascular thrombectomy (EVT) and the clinical outcomes of acute ischemic stroke (AIS) patients with large vessel occlusion (LVO). Methods: A study was eligible if it enrolled AIS patients older than 18 years, with an LVO treated with either successful or unsuccessful EVT, and provided either individual or mean 24-hour systolic BP values after the end of the EVT procedure. Individual patient data from all studies were analyzed using a generalized linear mixed-effects model. Results: A total of 5874 patients (mean age: 69±14 years, 50% women, median NIHSS on admission: 16) from 7 published studies were included. Increasing mean systolic BP levels per 10 mm Hg during the first 24 hours after the end of the EVT were associated with a lower odds of functional improvement (unadjusted common OR=0.82, 95%CI:0.80-0.85; adjusted common OR=0.88, 95%CI:0.84-0.93) and modified Ranking Scale score≤2 (unadjusted OR=0.82, 95%CI:0.79-0.85; adjusted OR=0.87, 95%CI:0.82-0.93), and a higher odds of all-cause mortality (unadjusted OR=1.18, 95%CI:1.13-1.24; adjusted OR=1.15, 95%CI:1.06-1.23) at 3 months. Higher 24-hour mean systolic BP levels were also associated with an increased likelihood of early neurological deterioration (unadjusted OR=1.14, 95%CI:1.07-1.21; adjusted OR=1.14, 95%CI:1.03-1.24) and a higher odds of symptomatic intracranial hemorrhage (unadjusted OR=1.20, 95%CI:1.09-1.29; adjusted OR=1.20, 95%CI:1.03-1.38) after EVT. Conclusion: Increased mean systolic BP levels in the first 24 hours after EVT are independently associated with a higher odds of symptomatic intracranial hemorrhage, early neurological deterioration, three-month mortality, and worse three-month functional outcomes."],["dc.description.abstract","Objective: To explore the association between blood pressure (BP) levels after endovascular thrombectomy (EVT) and the clinical outcomes of acute ischemic stroke (AIS) patients with large vessel occlusion (LVO). Methods: A study was eligible if it enrolled AIS patients older than 18 years, with an LVO treated with either successful or unsuccessful EVT, and provided either individual or mean 24-hour systolic BP values after the end of the EVT procedure. Individual patient data from all studies were analyzed using a generalized linear mixed-effects model. Results: A total of 5874 patients (mean age: 69±14 years, 50% women, median NIHSS on admission: 16) from 7 published studies were included. Increasing mean systolic BP levels per 10 mm Hg during the first 24 hours after the end of the EVT were associated with a lower odds of functional improvement (unadjusted common OR=0.82, 95%CI:0.80-0.85; adjusted common OR=0.88, 95%CI:0.84-0.93) and modified Ranking Scale score≤2 (unadjusted OR=0.82, 95%CI:0.79-0.85; adjusted OR=0.87, 95%CI:0.82-0.93), and a higher odds of all-cause mortality (unadjusted OR=1.18, 95%CI:1.13-1.24; adjusted OR=1.15, 95%CI:1.06-1.23) at 3 months. Higher 24-hour mean systolic BP levels were also associated with an increased likelihood of early neurological deterioration (unadjusted OR=1.14, 95%CI:1.07-1.21; adjusted OR=1.14, 95%CI:1.03-1.24) and a higher odds of symptomatic intracranial hemorrhage (unadjusted OR=1.20, 95%CI:1.09-1.29; adjusted OR=1.20, 95%CI:1.03-1.38) after EVT. Conclusion: Increased mean systolic BP levels in the first 24 hours after EVT are independently associated with a higher odds of symptomatic intracranial hemorrhage, early neurological deterioration, three-month mortality, and worse three-month functional outcomes."],["dc.identifier.doi","10.1212/WNL.0000000000013049"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/94554"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-478"],["dc.relation.eissn","1526-632X"],["dc.relation.issn","0028-3878"],["dc.title","Blood Pressure After Endovascular Thrombectomy and Outcomes in Patients With Acute Ischemic Stroke: An Individual Patient Data Meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2020Journal Article [["dc.bibliographiccitation.journal","Frontiers in Neurology"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Maier, Ilko L."],["dc.contributor.author","Hofer, Sabine"],["dc.contributor.author","Eggert, Eva"],["dc.contributor.author","Schregel, Katharina"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Bähr, Mathias"],["dc.contributor.author","Liman, Jan"],["dc.date.accessioned","2021-04-14T08:31:11Z"],["dc.date.available","2021-04-14T08:31:11Z"],["dc.date.issued","2020"],["dc.description.abstract","Age-related degeneration of the cervical spinal column is the most common cause of spinal cord lesions. T1 mapping has been shown to indicate the grade and site of spinal cord compression in low grade spinal canal stenosis (SCS). Aim of our study was to further investigate the diagnostic potential of a novel T1 mapping method at 0.75 mm resolution and 4 s acquisition time in 31 patients with various grades of degenerative cervical SCS. T1 mapping was performed in axial sections of the stenosis as well as above and below. Included subjects received standard T2-weighted MRI of the cervical spine (including SCS-grading 0-III), electrophysiological, and clinical examination. We found that patients with cervical SCS showed a significant difference in T1 relaxation times within the stenosis (727 ± 66 ms, mean ± standard deviation) in comparison to non-stenotic segments above (854 ± 104 ms, p \\u0026lt; 0.001) and below (893 ± 137 ms, p \\u0026lt; 0.001). There was no difference in mean T1 in non-stenotic segments in patients (p = 0.232) or between segments in controls (p = 0.272). Mean difference of the T1 relaxation times was significantly higher in grade III stenosis (234 ± 45) vs. in grade II stenosis (176 ± 45, p = 0.037) vs. in grade I stenosis (90 ± 87 ms, p = 0.010). A higher difference in T1 relaxation time was associated with a central efferent conduction deficit. In conclusion, T1 mapping may be useful as a tool for SCS quantification in all grades of SCS, including high-grade stenosis with myelopathy signal in conventional T2-weighted imaging."],["dc.identifier.doi","10.3389/fneur.2020.574604"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83508"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1664-2295"],["dc.rights","http://creativecommons.org/licenses/by/4.0/"],["dc.title","T1 Mapping Quantifies Spinal Cord Compression in Patients With Various Degrees of Cervical Spinal Canal Stenosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2017Journal Article [["dc.bibliographiccitation.firstpage","18"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Cerebrovascular Diseases"],["dc.bibliographiccitation.lastpage","25"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Maier, Ilko L."],["dc.contributor.author","Tsogkas, Ioannis"],["dc.contributor.author","Behme, Daniel"],["dc.contributor.author","Bähr, Mathias"],["dc.contributor.author","Knauth, Michael"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.contributor.author","Liman, Jan"],["dc.date.accessioned","2018-04-23T11:48:23Z"],["dc.date.available","2018-04-23T11:48:23Z"],["dc.date.issued","2017"],["dc.description.abstract","Background: Endovascular treatment (EVT) has been shown to significantly improve functional outcome in patients with acute large cerebral vessel occlusions. To date, no evidence-based recommendations on blood pressure management after successful EVT exist. Previous studies showed an association between high pre-EVT systolic blood pressure (SBP) and functional outcome, but do not answer the question on how to manage blood pressure after successful recanalization. The purpose of this study was to determine the role of blood pressure measurements as a predictor for early functional outcome in patients with successful EVT. Methods: Prospectively derived data from patients with acute large vessel occlusion within the anterior circulation and EVT was analyzed in this monocentric study. Mean systolic- and maximum SBP as well as SBP-peaks have been obtained for the first 24 h after successful EVT. Predictive value of SBP for discharge modified Rankin Scale (mRS) ≤2 has been investigated using logistic regression models. Results: From 168 patients with successful EVT, 74 (44%) had a favorable outcome with an mRS ≤2. Mean- (127 vs. 131 mm Hg, p = 0.035) and maximum SBP (157 vs. 169 mm Hg, p < 0.001) as well as the number of SBP-peaks (0 vs. 1.5, p = 0.004) were lower in patients with favorable outcomes. Multivariable logistic regression showed high mean- and maximum SBP to predict unfavorable outcomes. Cutoff mean SBP was 141 mm Hg and maximum SBP 159 mm Hg. Conclusions: High SBP in the first 24 h after recanalization of acute anterior cerebral vessel occlusions is associated with unfavorable functional outcome. Interventional studies are needed to determine the role of SBP management as a modifiable parameter in the early phase after successful EVT."],["dc.identifier.doi","10.1159/000484720"],["dc.identifier.gro","3142065"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/13499"],["dc.language.iso","en"],["dc.notes.intern","lifescience updates Crossref Import"],["dc.notes.status","final"],["dc.relation.issn","1015-9770"],["dc.title","High Systolic Blood Pressure after Successful Endovascular Treatment Affects Early Functional Outcome in Acute Ischemic Stroke"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]Details DOI2020Journal Article [["dc.bibliographiccitation.firstpage","932"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Journal of NeuroInterventional Surgery"],["dc.bibliographiccitation.lastpage","936"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Anadani, Mohammad"],["dc.contributor.author","Arthur, Adam S."],["dc.contributor.author","Alawieh, Ali"],["dc.contributor.author","Orabi, Yser"],["dc.contributor.author","Alexandrov, Andrei"],["dc.contributor.author","Goyal, Nitin"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.contributor.author","Maier, Ilko"],["dc.contributor.author","Kim, Joon-tae"],["dc.contributor.author","Keyrouz, Saleh G."],["dc.contributor.author","de Havenon, Adam"],["dc.contributor.author","Petersen, Nils H."],["dc.contributor.author","Pandhi, Abhi"],["dc.contributor.author","Swisher, Christa B."],["dc.contributor.author","Inamullah, Ovais"],["dc.contributor.author","Liman, Jan"],["dc.contributor.author","Kodali, Sreeja"],["dc.contributor.author","Giles, James A."],["dc.contributor.author","Allen, Michelle"],["dc.contributor.author","Wolfe, Stacey Q."],["dc.contributor.author","Tsivgoulis, Georgios"],["dc.contributor.author","Cagle, Bradley A."],["dc.contributor.author","Oravec, Chesney S."],["dc.contributor.author","Gory, Benjamin"],["dc.contributor.author","De Marini, Pierre"],["dc.contributor.author","Kan, Peter"],["dc.contributor.author","Rahman, Shareena"],["dc.contributor.author","Richard, Sébastien"],["dc.contributor.author","Nascimento, Fábio A."],["dc.contributor.author","Spiotta, Alejandro"],["dc.date.accessioned","2021-04-14T08:32:51Z"],["dc.date.available","2021-04-14T08:32:51Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1136/neurintsurg-2019-015561"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/84037"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1759-8486"],["dc.relation.issn","1759-8478"],["dc.title","Blood pressure reduction and outcome after endovascular therapy with successful reperfusion: a multicenter study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2017Journal Article [["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Maier, Ilko L."],["dc.contributor.author","Behme, Daniel"],["dc.contributor.author","Schnieder, Marlena"],["dc.contributor.author","Tsogkas, Ioannis"],["dc.contributor.author","Schregel, Katharina"],["dc.contributor.author","Bähr, Mathias"],["dc.contributor.author","Knauth, Michael"],["dc.contributor.author","Liman, Jan"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.date.accessioned","2018-01-08T17:09:39Z"],["dc.date.available","2018-01-08T17:09:39Z"],["dc.date.issued","2017"],["dc.description.abstract","Identification of patients requiring decompressive hemicraniectomy (DH) after endovascular therapy (EVT) is crucial as clinical signs are not reliable and early DH has been shown to improve clinical outcome. The aim of our study was to identify imaging-based scores to predict the risk for space occupying ischemic stroke and DH."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2017"],["dc.identifier.doi","10.1371/journal.pone.0173737"],["dc.identifier.pmid","28282456"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14394"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/11572"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.eissn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Early computed tomography-based scores to predict decompressive hemicraniectomy after endovascular therapy in acute ischemic stroke"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2017Journal Article [["dc.bibliographiccitation.artnumber","1391843"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Stroke Research and Treatment"],["dc.bibliographiccitation.lastpage","6"],["dc.bibliographiccitation.volume","2017"],["dc.contributor.author","Maier, Ilko L."],["dc.contributor.author","Schregel, Katharina"],["dc.contributor.author","Karch, André"],["dc.contributor.author","Weber-Krueger, Mark"],["dc.contributor.author","Mikolajczyk, Rafael T."],["dc.contributor.author","Stahrenberg, Raoul"],["dc.contributor.author","Gröschel, Klaus"],["dc.contributor.author","Bähr, Mathias"],["dc.contributor.author","Knauth, Michael"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Liman, Jan"],["dc.date.accessioned","2018-04-23T11:47:07Z"],["dc.date.available","2018-04-23T11:47:07Z"],["dc.date.issued","2017"],["dc.description.abstract","Background. Atrial fibrillation (AF) is an important cause of embolic stroke of undetermined source (ESUS). Imaging-patterns like multiple infarcts, simultaneous involvement of different circulations, infarcts of different ages, and isolated cortical infarcts are likely to indicate cardioembolic stroke. The aim of our study was to evaluate the association between embolic stroke patterns, ESUS, and the new diagnosis of AF. Methods. Stroke etiology and imaging characteristics from patients included in the Find-AF study were obtained. Embolic stroke patterns in CT- or MR-imaging were correlated with the diagnosis of ESUS as well as the short- (on baseline ECG and during 7-day Holter) and long-term (12-month follow-up) diagnosis of AF. Results. From 281 patients included in the Find-AF study, 127 (45.2%) patients with ischemic lesions detected in CT or MRI were included. 26 (20.5%) of these patients had ESUS. At least one embolic stroke pattern was detected in 67 (52.7%) patients. Embolic stroke patterns were not associated with ESUS (OR 1.57, 0.65–3.79, ), the short-term (OR 0.64, 0.26–1.58, ) or long-term diagnosis of AF (OR 0.72, 0.31–1.68, ). Conclusions. This secondary data analysis of the Find-AF study could not provide evidence for an association between embolic stroke patterns, ESUS, and the new diagnosis of AF."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2017"],["dc.identifier.doi","10.1155/2017/1391843"],["dc.identifier.gro","3142074"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14531"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/13300"],["dc.language.iso","en"],["dc.notes.intern","lifescience updates Crossref Import"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","2090-8105"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Association between Embolic Stroke Patterns, ESUS Etiology, and New Diagnosis of Atrial Fibrillation: A Secondary Data Analysis of the Find-AF Trial"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI