Braunschweig, Lena

[["dc.bibliographiccitation.firstpage","272"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The Journal of Foot and Ankle Surgery"],["dc.bibliographiccitation.lastpage","278"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Eysel, Lara O."],["dc.contributor.author","Lüders, Katja A."],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Lorenz, Heiko M."],["dc.contributor.author","Dörner, Jochen"],["dc.contributor.author","Hell, Anna K."],["dc.contributor.author","Stinus, Hartmut"],["dc.date.accessioned","2022-09-01T09:50:15Z"],["dc.date.available","2022-09-01T09:50:15Z"],["dc.date.issued","2022"],["dc.description.abstract","Flexible flatfoot is among the most common skeletal disorders in childhood. This study describes the dynamic and static correction effects of subtalar arthroereisis in adolescents with flexible symptomatic flatfeet in comparison to normal subjects as well as to results before and after removal of metal. Eighteen adolescents with 25 symptomatic flexible flatfeet were treated surgically with a subtalar arthroereisis at a mean of 12.5 (10-16) years. At follow-up (mean 3.9 years, range 0.4-8), patients filled out the American Orthopaedic Foot and Ankle Society questionnaire, received radiographs and were examined using dynamic and static pedobarography as well as static hindfoot axis examination. Results were compared to healthy controls (n = 13; 26 feet). Surgically treated feet (n = 25) had better questionnaire results after surgery than before, but lower scores than healthy feet. Radiological parameters improved significantly after surgery. Removal of metal did not influence post-surgical results (follow-up 2.8 years). Surgically treated feet had larger contact areas than normal feet with predominance to the midfoot region. The relative maximum force, relative peak pressure and contact time were higher in the midfoot of treated feet compared to controls. When comparing pedobarography data of treated versus untreated feet of the same patients (subgroup n = 11 feet), there were no differences. Subtalar arthroereisis was able to effectively treat symptomatic flexible flatfeet in this population. Results improved significantly evaluating a questionnaire, radiographs, dynamic and static weight distribution, but were still worse than results of healthy feet. There was no relapse after removal of metal."],["dc.identifier.doi","10.1053/j.jfas.2021.07.021"],["dc.identifier.pii","S1067251621002751"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113661"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.issn","1067-2516"],["dc.relation.orgunit","Klinik für Unfallchirurgie, Orthopädie und Plastische Chirurgie"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Foot Typology, Dynamic and Static Weight Distribution, and Radiographic Changes After Subtalar Arthroereisis in Juvenile Symptomatic Flexible Flat Feet"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Spine Journal"],["dc.contributor.author","Lippross, Sebastian"],["dc.contributor.author","Grages, Antonia"],["dc.contributor.author","Lueders, Katja A."],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Austein, Friederike"],["dc.contributor.author","Tsaknakis, Konstantinos"],["dc.contributor.author","Lorenz, Heiko M."],["dc.contributor.author","Hell, Anna K."],["dc.date.accessioned","2021-04-14T08:29:12Z"],["dc.date.available","2021-04-14T08:29:12Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1007/s00586-021-06775-7"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82828"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1432-0932"],["dc.relation.issn","0940-6719"],["dc.title","Vertebral body changes after continuous spinal distraction in scoliotic children"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","World Neurosurgery"],["dc.contributor.author","Hell, Anna K."],["dc.contributor.author","Grages, Antonia"],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Lueders, Katja A."],["dc.contributor.author","Austein, Friederike"],["dc.contributor.author","Lorenz, Heiko M."],["dc.contributor.author","Lippross, Sebastian"],["dc.contributor.author","Tsaknakis, Konstantinos"],["dc.date.accessioned","2022-07-01T07:34:41Z"],["dc.date.available","2022-07-01T07:34:41Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.wneu.2022.06.054"],["dc.identifier.pii","S1878875022008397"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/111991"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.issn","1878-8750"],["dc.title","Children with spinal muscular atrophy have reduced vertebral body height, depth and pedicle size in comparison to age-matched healthy controls"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e334"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of Pediatric Orthopaedics"],["dc.bibliographiccitation.lastpage","e338"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Lorenz, Heiko M."],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Badwan, Batoul"],["dc.contributor.author","Groenefeld, Katharina"],["dc.contributor.author","Hecker, Marina M."],["dc.contributor.author","Tsaknakis, Konstantinos"],["dc.contributor.author","Grote, Jasmin"],["dc.contributor.author","Hell, Anna K."],["dc.date.accessioned","2020-12-10T18:19:49Z"],["dc.date.available","2020-12-10T18:19:49Z"],["dc.date.issued","2019"],["dc.description.abstract","Magnetically controlled implant systems have been established to treat severe progressive spinal deformity in children. The purpose of this study was to evaluate (1) the ratio between achieved and expected distraction length, (2) the complication rate and its risk factors as well as (3) the correlation of the distraction length and the length of the spine."],["dc.identifier.doi","10.1097/BPO.0000000000001303"],["dc.identifier.issn","0271-6798"],["dc.identifier.pmid","30451815"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75392"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation.eissn","1539-2570"],["dc.relation.issn","0271-6798"],["dc.title","High Correlation Between Achieved and Expected Distraction Using Magnetically Controlled Growth Rods (MCGR) With Rib to Pelvis Fixation in Pediatric Spine Deformity"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2662"],["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","Human Molecular Genetics"],["dc.bibliographiccitation.lastpage","2673"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Hensel, Niko"],["dc.contributor.author","Brickwedde, Hermann"],["dc.contributor.author","Tsaknakis, Konstantinos"],["dc.contributor.author","Grages, Antonia"],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Lüders, Katja A"],["dc.contributor.author","Lorenz, Heiko M"],["dc.contributor.author","Lippross, Sebastian"],["dc.contributor.author","Walter, Lisa M"],["dc.contributor.author","Tavassol, Frank"],["dc.contributor.author","Lienenklaus, Stefan"],["dc.contributor.author","Neunaber, Claudia"],["dc.contributor.author","Claus, Peter"],["dc.contributor.author","Hell, Anna K"],["dc.date.accessioned","2021-04-14T08:24:15Z"],["dc.date.available","2021-04-14T08:24:15Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1093/hmg/ddaa145"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81217"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1460-2083"],["dc.relation.issn","0964-6906"],["dc.title","Altered bone development with impaired cartilage formation precedes neuromuscular symptoms in spinal muscular atrophy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","688"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Neurosurgery: Pediatrics"],["dc.bibliographiccitation.lastpage","693"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Mladenov, Kiril"],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Behrend, Jennifer"],["dc.contributor.author","Lorenz, Heiko M."],["dc.contributor.author","von Deimling, Urs"],["dc.contributor.author","Hell, Anna K."],["dc.date.accessioned","2020-12-10T18:44:05Z"],["dc.date.available","2020-12-10T18:44:05Z"],["dc.date.issued","2019"],["dc.description.abstract","OBJECTIVEDuring childhood, early-onset scoliosis (EOS) may show severe progressive deformity, which consequently leads to aggressive treatment strategies, such as serial casting, long-term bracing, or surgical interventions. The latter usually includes repeated surgeries for implant lengthening every 6 months in order to allow sufficient growth of the thorax and spine. In 2011, the 24-item Early-Onset Scoliosis Questionnaire (EOSQ-24) was introduced to measure health-related quality of life for this patient group and their families. Since then, cross-culturally adapted versions of the EOSQ-24 have been published in Spanish, Turkish, traditional Chinese, and Norwegian. The purpose of the study was to transculturally adapt the original English version of the EOSQ-24 into the German language and evaluate the reliability of the German version.METHODSAfter adaptation and forward/backward translation, the German version of the EOSQ-24 was given to the parents or caregivers of 67 EOS patients (33 male, 34 female) Data quality was evaluated by mean, standard deviation, percentage of data missing, and extent of ceiling and floor effects. Reliability was estimated by internal consistency using Cronbach α and item-total correlations.RESULTSIn the study group (n = 67), 12 children were either observed (n = 7) or treated with a brace (n = 5). The other 55 patients were treated surgically with growth-friendly implants. The item response to the German EOSQ-24 was high with a minimum of missing data (1.7%). All items showed very good to excellent internal consistencies (0.879-0.903). Floor effects for the 24 items were between 0% and 31% and ceiling effects between 9% and 78%. The calculated Cronbach α for the 24-item scale was 0.9003, indicating excellent reliability.CONCLUSIONSThe German adaptation of the EOSQ-24 shows excellent reliability and therefore is a valid tool to measure objective health-related quality of life in children with EOS."],["dc.identifier.doi","10.3171/2019.1.PEDS18704"],["dc.identifier.eissn","1933-0715"],["dc.identifier.issn","1933-0707"],["dc.identifier.pmid","30849744"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78322"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation.eissn","1933-0715"],["dc.relation.issn","1933-0707"],["dc.title","Validation of the German version of the 24-item Early-Onset Scoliosis Questionnaire"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Pediatric Orthopaedics. Part B"],["dc.contributor.author","Tsaknakis, Konstantinos"],["dc.contributor.author","Schmalz, Thomas"],["dc.contributor.author","Freslier, Marie"],["dc.contributor.author","Tsaknakis, Birgit"],["dc.contributor.author","Lorenz, Heiko M."],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Hell, Anna K."],["dc.date.accessioned","2021-06-01T10:46:56Z"],["dc.date.available","2021-06-01T10:46:56Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1097/BPB.0000000000000858"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85429"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","1060-152X"],["dc.title","Limited trunk motion and posterior pelvic tilting in ambulatory children treated with bilateral rib to pelvis implants for spinal deformity control"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Osteoporosis International"],["dc.contributor.author","Tsaknakis, K."],["dc.contributor.author","Jäckle, K."],["dc.contributor.author","Lüders, K. A."],["dc.contributor.author","Lorenz, H. M."],["dc.contributor.author","Braunschweig, L."],["dc.contributor.author","Hell, A. K."],["dc.date.accessioned","2022-06-01T09:39:31Z"],["dc.date.available","2022-06-01T09:39:31Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1007/s00198-022-06416-9"],["dc.identifier.pii","6416"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108500"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","1433-2965"],["dc.relation.issn","0937-941X"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","Reduced bone mineral density in adolescents with Duchenne Muscular Dystrophy (DMD) and scoliosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Lüders, K. A."],["dc.contributor.author","Braunschweig, L."],["dc.contributor.author","Zioła-Frankowska, A."],["dc.contributor.author","Stojek, A."],["dc.contributor.author","Jakkielska, D."],["dc.contributor.author","Wichmann, A."],["dc.contributor.author","Dihazi, G. H."],["dc.contributor.author","Streit, F,"],["dc.contributor.author","Güsewell, S. E."],["dc.contributor.author","Trüe, T. C."],["dc.contributor.author","Hell, A. K."],["dc.date.accessioned","2022-07-01T07:34:54Z"],["dc.date.available","2022-07-01T07:34:54Z"],["dc.date.issued","2022"],["dc.description.abstract","Magnetically controlled growing rods (MCGRs) are an effective treatment method for early-onset scoliosis (EOS). In recent years, increasing titanium wear was observed in tissue adjacent to implants and in blood samples of these patients. This study aims to investigate the potential correlation between amount of metal loss and titanium levels in blood during MCGR treatment as well as influencing factors for metal wear. In total, 44 MCGRs ( n  = 23 patients) were retrieved after an average of 2.6 years of implantation and analyzed using a tactile measurement instrument and subsequent metal loss calculation. Titanium plasma levels ( n  = 23) were obtained using inductively coupled plasma-mass spectrometry (ICP-MS). The correlation of both parameters as well as influencing factors were analyzed. Titanium abrasion on MCGRs was observed in the majority of implants. There was no correlation of metal implant wear or titanium plasma values to the duration of MCGR implantation time, number of external lengthening procedures, patient\\’s ambulatory status, gender, weight or height. Material loss on the MCGRs showed a positive correlation to titanium blood plasma values. The present study is one of the first studies to analyze retrieved MCGRs using high-precision metrological techniques and compare these results with ICP-MS analyses determining blood titanium values."],["dc.description.sponsorship"," Bundesministerium für Bildung und Forschung http://dx.doi.org/10.13039/501100002347"],["dc.description.sponsorship"," Uniwersytet im. Adama Mickiewicza w Poznaniu http://dx.doi.org/10.13039/501100013920"],["dc.description.sponsorship","Herzzentrum Göttingen"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.1038/s41598-022-15057-1"],["dc.identifier.pii","15057"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112036"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.eissn","2045-2322"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Titanium wear from magnetically controlled growing rods (MCGRs) for the treatment of spinal deformities in children"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","239"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Clinical Spine Surgery"],["dc.bibliographiccitation.lastpage","246"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Hell, Anna K."],["dc.contributor.author","Groenefeld, Katharina"],["dc.contributor.author","Tsaknakis, Konstantinos"],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Lorenz, Heiko M."],["dc.date.accessioned","2020-12-10T18:19:49Z"],["dc.date.available","2020-12-10T18:19:49Z"],["dc.date.issued","2018"],["dc.description.abstract","Spine-based fixation of magnetically controlled lengthening devices has been successfully performed for children with early-onset scoliosis. However, spinal manipulation may lead to ossifications, stiffness, and autofusion as previously described. To avoid these problems, a surgical technique combining bilateral externally controlled magnetic device implantation with a rib cradle and pelvic hook fixation was introduced by us in 2011. By using a bilateral single-rib or double-rib cradle fixation and a pelvic hook, the magnetic device is percutaneously inserted. The spine corrects indirectly without further manipulation. In small rib diameter or severe osteoporosis, double-rib cradles are used. Our introduced technique enables modification of the rib vertebral angle, which may be beneficial in children with spinal muscular atrophy and rib-cage deformity. This nonrandomized prospective study describes 18 children with neuromuscular scoliosis treated first by this method. All patients followed the same protocol, with expansion procedures being performed 5 months after surgery and every 3 months thereafter. Clinical, radiologic, and complication data were analyzed, showing a significant reduction in scoliosis and pelvic obliquity and an increase in spinal length, which could be maintained over a follow-up period of 1.2 years. The overall complication rate was lower than previously described, with 8%, 2 of them requiring surgery."],["dc.identifier.doi","10.1097/BSD.0000000000000614"],["dc.identifier.issn","2380-0186"],["dc.identifier.pmid","29369154"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75393"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","final"],["dc.relation.eissn","2380-0194"],["dc.title","Combining Bilateral Magnetically Controlled Implants Inserted Parallel to the Spine With Rib to Pelvis Fixation"],["dc.title.alternative","Surgical Technique and Early Results"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]