Tröltzsch, Markus

[["dc.bibliographiccitation.firstpage","1095"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of Cranio-Maxillofacial Surgery"],["dc.bibliographiccitation.lastpage","1103"],["dc.bibliographiccitation.volume","44"],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.contributor.author","Krohn, Sebastian"],["dc.contributor.author","Thiemann, Charlotte"],["dc.contributor.author","Schulz, Xenia"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Troeltzsch, Markus"],["dc.contributor.author","Schlottig, Falk"],["dc.contributor.author","Schliephake, Henning"],["dc.contributor.author","Gruber, Rudolf Matthias"],["dc.date.accessioned","2018-11-07T10:11:07Z"],["dc.date.available","2018-11-07T10:11:07Z"],["dc.date.issued","2016"],["dc.description.abstract","The present study aimed to evaluate primary stability (PS) and osseointegration of dental implants in polylactide [70/30 poly(L-lactide-co-o, L-lactide); (PLDLA)1 modified bone in 30 Goettingen minipigs. Each animal received three implants per jaw quadrant. In a split -mouth design, one side of the maxilla and mandible was randomly allocated to the experimental treatment (PLDLA applied into the drill hole before implantation), while the contralateral sides served as intraindividual controls (no PLDLA applied). The required insertion torque and the implant stability quotient (ISQ) were measured during implantation. ISQ volume density (VD) of new bone formation (NBF), and the bone -implant contact (BIC) were evaluated at the end of the observation period (1, 3, 6, 12, and 24 months, respectively) in six animals each. Across all study groups, the PLDLA treatment resulted in a) a comparable insertion torque, b) an equivalent ISQ c) a reduced BIC, and d) a reduced VD of NBF, as opposed to the untreated controls. In conclusion, the PLDLA treatment did not affect the PS, but rather led to an impaired osseointegration, which was particularly strong in the compact mandibular bone, and decreased in the spongious maxillary bone. PLDLA induced anchoring in spongious bone should be evaluated in further investigations. (C) 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved."],["dc.description.sponsorship","Thommen Medical AG, Grenchen, Switzerland"],["dc.identifier.doi","10.1016/j.jcms.2016.05.025"],["dc.identifier.isi","000381322200029"],["dc.identifier.pmid","27346283"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39987"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Churchill Livingstone"],["dc.relation.issn","1878-4119"],["dc.relation.issn","1010-5182"],["dc.title","Primary stability and osseointegration of dental implants in polylactide modified bone - A pilot study in Goettingen minipigs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","clr.13820"],["dc.bibliographiccitation.firstpage","1228"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Clinical Oral Implants Research"],["dc.bibliographiccitation.lastpage","1240"],["dc.bibliographiccitation.volume","32"],["dc.contributor.affiliation","Raschke, David; 1Department for Oral & Maxillofacial Surgery Universitätsmedizin Goettingen Goettingen Germany"],["dc.contributor.affiliation","Tröltzsch, Markus; 2Private Office Ansbach Germany & Department for Oral & Maxillofacial Surgery Universitätsmedizin Goettingen Goettingen Germany"],["dc.contributor.affiliation","Santander, Petra; 3Department of Orthodontics Universitätsmedizin Göttingen Goettingen Germany"],["dc.contributor.affiliation","Brockmeyer, Phillip; 1Department for Oral & Maxillofacial Surgery Universitätsmedizin Goettingen Goettingen Germany"],["dc.contributor.affiliation","Schliephake, Henning; 1Department for Oral & Maxillofacial Surgery Universitätsmedizin Goettingen Goettingen Germany"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Raschke, David"],["dc.contributor.author","Tröltzsch, Markus"],["dc.contributor.author","Santander, Petra"],["dc.contributor.author","Brockmeyer, Phillip"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2021-09-01T06:42:53Z"],["dc.date.available","2021-09-01T06:42:53Z"],["dc.date.issued","2021"],["dc.date.updated","2022-03-21T09:20:33Z"],["dc.description.abstract","Abstract Aim To test the hypothesis that the use of rhBMP2 in established defects requires additional growth factors such as rhVEGF to accomplish effective bone repair. Materials and Methods Horizontal/vertical defects of 2 cm length and 1 cm height were created bilaterally in the alveolar crest of the maxillae of 18 minipigs together with the extraction of all premolar teeth and one molar tooth on both sides. After 3 months of healing, defects were augmented with 0.5 g particulate PDLLA/CaCO3 composite loaded with 400 µg rhBMP2/50 µg rhVEGF165 on one side and 800 µg rhBMP2 on the other in 12 test animals, whereas defects in six control animals were sham operated and left unfilled on one side and augmented with blank carriers on the other. After 4 and 13 weeks, the animals were evaluated each for area of new bone formation (mm²) and bone density (area %). Results Augmentations with carriers loaded with 800 g µrhBMP2 failed to induce significantly more bone than in the augmentations with unloaded carrier after 4 and 13 weeks (p = .1000, p = .381). Augmentations with carriers loaded with 400 µg rhBMP2 and 50 µg erhVEGF165 resulted in significantly increased bone formation after 13 weeks (p = .024) compared to blank carriers. Soft tissue in augmentations with combined rhBMP2/rhVEGF165 loading exhibited numerous microvessels compared to soft tissue in augmentations with rhBMP2. Conclusions It is concluded that effective bone regeneration in augmentations of established alveolar ridge defects may require the application of rhVEGF additionally to rhBMP2."],["dc.description.sponsorship","KLS MARTIN"],["dc.identifier.doi","10.1111/clr.13820"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89167"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-455"],["dc.relation.eissn","1600-0501"],["dc.relation.issn","0905-7161"],["dc.rights","This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes."],["dc.title","The use of rhBMP2 for augmentation of established horizontal/vertical defects may require additional use of rhVEGF to achieve significant bone regeneration: An in vivo experimental study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1618"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery"],["dc.bibliographiccitation.lastpage","1629"],["dc.bibliographiccitation.volume","44"],["dc.contributor.author","Troeltzsch, Markus"],["dc.contributor.author","Troeltzsch, Matthias"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Gruber, Rudolph"],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.contributor.author","Moser, Norman"],["dc.contributor.author","Rau, Anna"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-06-25T07:48:54Z"],["dc.date.available","2018-06-25T07:48:54Z"],["dc.date.issued","2016-10"],["dc.description.abstract","To evaluate the efficacy of grafting materials in lateral and vertical ridge augmentations."],["dc.identifier.doi","10.1016/j.jcms.2016.07.028"],["dc.identifier.pmid","27622971"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15135"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1878-4119"],["dc.title","Clinical efficacy of grafting materials in alveolar ridge augmentation: A systematic review"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","11"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],["dc.bibliographiccitation.lastpage","15"],["dc.bibliographiccitation.volume","124"],["dc.contributor.author","Cordesmeyer, Robert"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Tröltzsch, Markus"],["dc.contributor.author","Sömmer, Christian"],["dc.contributor.author","Eiffert, Helmut"],["dc.contributor.author","Bremmer, Felix"],["dc.contributor.author","Laskawi, Rainer"],["dc.date.accessioned","2018-10-10T09:37:57Z"],["dc.date.available","2018-10-10T09:37:57Z"],["dc.date.issued","2017-07"],["dc.description.abstract","Deep neck infections are among the most dangerous acute diseases in the head and neck region. This analysis gives an overview of the bacterial and histopathologic findings of deep neck infections."],["dc.identifier.doi","10.1016/j.oooo.2017.02.003"],["dc.identifier.gro","631840"],["dc.identifier.pmid","28411005"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15934"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","2212-4411"],["dc.title","Bacterial and histopathological findings in deep head and neck infections: a retrospective analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","453"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","Clinical Hemorheology and Microcirculation"],["dc.bibliographiccitation.lastpage","457"],["dc.bibliographiccitation.volume","67"],["dc.contributor.author","Kauffmann, P."],["dc.contributor.author","Troeltzsch, M."],["dc.contributor.author","Cordesmeyer, R."],["dc.contributor.author","Heidekrueger, P.I."],["dc.contributor.author","Schliephake, H."],["dc.contributor.author","Canis, M."],["dc.contributor.author","Wolff, H.A."],["dc.contributor.author","Rave-Fraenk, M."],["dc.contributor.author","Stroebel, P."],["dc.contributor.author","Kehrer, A."],["dc.contributor.author","Prantl, L."],["dc.contributor.author","Aung, T."],["dc.contributor.editor","Jünger, M."],["dc.contributor.editor","Krüger-Genge, A."],["dc.contributor.editor","Jung, F."],["dc.date.accessioned","2020-12-10T18:44:09Z"],["dc.date.available","2020-12-10T18:44:09Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.3233/CH-179226"],["dc.identifier.eissn","1875-8622"],["dc.identifier.issn","1386-0291"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78345"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Presentation of a variation of the chorioallantoic membrane set up as a potential model for individual therapy for squamous cell carcinoma of the oropharynx"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","20"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Oral surgery, oral medicine, oral pathology and oral radiology"],["dc.bibliographiccitation.lastpage","28"],["dc.bibliographiccitation.volume","123"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Hahn, Wolfram"],["dc.contributor.author","Sievers, Niklas"],["dc.contributor.author","Troeltzsch, Markus"],["dc.contributor.author","Hohloch, Karin"],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.contributor.author","Cordesmeyer, Robert"],["dc.contributor.author","Schliephake, Henning"],["dc.contributor.author","Gruber, Rudolf Matthias"],["dc.date.accessioned","2018-06-25T07:43:01Z"],["dc.date.available","2018-06-25T07:43:01Z"],["dc.date.issued","2017-01"],["dc.description.abstract","We compared the intraindividual effects of increasing zoledronic acid (ZA) concentrations on osteoblast-like cells with different embryologic origins."],["dc.fs.pkfprnr","2489"],["dc.identifier.doi","10.1016/j.oooo.2016.08.010"],["dc.identifier.fs","626267"],["dc.identifier.pmid","27720655"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15133"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","2212-4411"],["dc.title","Osteoblast-like cells with different embryologic origins behave differently in increasing zoledronic acid concentrations: a pilot study in pigs"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1784"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Journal of Cranio-Maxillofacial Surgery"],["dc.bibliographiccitation.lastpage","1787"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Cordesmeyer, Robert"],["dc.contributor.author","Schliephake, Henning"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Tröltzsch, Markus"],["dc.contributor.author","Laskawi, Rainer"],["dc.contributor.author","Ströbel, Philipp"],["dc.contributor.author","Bremmer, Felix"],["dc.date.accessioned","2018-10-10T09:31:29Z"],["dc.date.available","2018-10-10T09:31:29Z"],["dc.date.issued","2017-11"],["dc.description.abstract","Adenoid cystic carcinomas are rare malignant tumors of the salivary glands. They are characterized by a high rate of local recurrence, late distant metastasis and a poor disease-free survival. In this study, we analyzed a series of 61 patients who were all treated at the University of Göttingen over a period of 21.0 years."],["dc.identifier.doi","10.1016/j.jcms.2017.08.004"],["dc.identifier.gro","631841"],["dc.identifier.pmid","28935487"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15932"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1878-4119"],["dc.title","Clinical prognostic factors of salivary adenoid cystic carcinoma: A single-center analysis of 61 patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","E82"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Oral Oncology"],["dc.bibliographiccitation.lastpage","E85"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.contributor.author","Hemmerlein, Bernhard"],["dc.contributor.author","Kruppa, Jochen"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Troeltzsch, Markus"],["dc.contributor.author","Schliephake, Henning"],["dc.contributor.author","Gruber, Rudolf Matthias"],["dc.date.accessioned","2018-11-07T09:49:49Z"],["dc.date.available","2018-11-07T09:49:49Z"],["dc.date.issued","2015"],["dc.identifier.doi","10.1016/j.oraloncology.2015.08.016"],["dc.identifier.isi","000363484800002"],["dc.identifier.pmid","26391506"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35578"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1879-0593"],["dc.relation.issn","1368-8375"],["dc.title","The time interval between primary surgery and adjuvant therapy determines prognosis of oral squamous cell carcinomas"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","854"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of Clinical Periodontology"],["dc.bibliographiccitation.lastpage","863"],["dc.bibliographiccitation.volume","44"],["dc.contributor.author","Tröltzsch, Markus"],["dc.contributor.author","Klenke, Alexander"],["dc.contributor.author","Santander, Petra"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Tröltzsch, Matthias"],["dc.contributor.author","Rau, Anna"],["dc.contributor.author","Brockmeyer, Phillipp"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-10-10T09:14:47Z"],["dc.date.available","2018-10-10T09:14:47Z"],["dc.date.issued","2017-08"],["dc.description.abstract","To test the hypothesis that the addition of small amounts of rhVEGF to rhBMP2 in a polymer carrier can accomplish equivalent repair effect as a reduced dosage of rhBMP2 compared to rhBMP2 alone. Defects were created bilaterally in the mandibles of 18 mini-pigs. In 12 test animals, defects were filled with 0.5g particulate PDLLA/CaCO3 composite loaded with 400μg rhBMP2/50μg rhVEGF165 on one side and 800μg rhBMP2 on the other. After 4 and 13 weeks, the animals were evaluated each for area of new bone formation (mm²) and bone density (area %). Area of newly formed bone was higher in defects with carriers loaded with 400 μg rhBMP2 50 μg VEGF165 than in defects with 800 μg rhBMP2 after 4 weeks (11.97 versus 7.97mm²; p=0.043) and 13 weeks (72.48 versus 62.2mm²; p= .028). Defects filled with blank carrier exhibited less bone after 13 weeks (42.75mm²; p= .039 and .020 respectively). Delivery of rhBMP2 from a polymer carrier can improve repair of large saddle defects of the mandibular ridge. Addition of small amounts of rhVEGF can increase bone formation and at the same time reduce the dosage of rhBMP2."],["dc.fs.pkfprnr","60855"],["dc.identifier.doi","10.1111/jcpe.12739"],["dc.identifier.fs","633112"],["dc.identifier.pmid","28453232"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15930"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1600-051X"],["dc.title","Repair of large saddle defects of the mandibular ridge using dual growth factor release - An experimental pilot study in minipigs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e536"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Medicina oral, patologia oral y cirugia bucal"],["dc.bibliographiccitation.lastpage","e541"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Kauffmann, Philipp"],["dc.contributor.author","Cordesmeyer, Robert"],["dc.contributor.author","Tröltzsch, Markus"],["dc.contributor.author","Sömmer, Christian"],["dc.contributor.author","Laskawi, Rainer"],["dc.date.accessioned","2018-10-10T09:26:33Z"],["dc.date.available","2018-10-10T09:26:33Z"],["dc.date.issued","2017"],["dc.description.abstract","With the use of antibiotic therapy, the incidence of deep neck infections has decreased in recent decades. The aim of this investigation was to review the clinical course and the management of deep neck infections in our department, compare them to the experiences of the common literature and identify predisposing factors for lethal complications."],["dc.identifier.doi","10.4317/medoral.21799"],["dc.identifier.gro","632595"],["dc.identifier.pmid","28809368"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15931"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1698-6946"],["dc.title","Deep neck infections: A single-center analysis of 63 cases"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]