Müller, Markus

[["dc.bibliographiccitation.firstpage","3235"],["dc.bibliographiccitation.issue","19"],["dc.bibliographiccitation.journal","NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS"],["dc.bibliographiccitation.lastpage","3238"],["dc.bibliographiccitation.volume","268"],["dc.contributor.author","Chappa, Veronica C."],["dc.contributor.author","Pastorino, Claudio"],["dc.contributor.author","del Grosso, M. F."],["dc.contributor.author","Arbeitman, C. R."],["dc.contributor.author","Mueller, M."],["dc.contributor.author","Garcia Bermudez, G."],["dc.date.accessioned","2018-11-07T08:38:46Z"],["dc.date.available","2018-11-07T08:38:46Z"],["dc.date.issued","2010"],["dc.description.abstract","In this work we study a polymeric material that degrades upon irradiation due to the energy inhomogeneously deposited by heavy ion beams. Ion beam irradiation of polymers generates rather different effects than those induced by \"classical\" low ionizing particles such as electrons or gamma rays. This is due to the high electronic stopping power and the inhomogeneous distribution of deposited energy. This energy is transferred to the material within a small volume along the ion path forming the so called \"nuclear track\" or \"latent track\". The track size primarily depends on the ion velocity, and it is determined by the secondary electrons (delta rays) generated along the ion trajectory. By means of Monte Carlo simulations we first obtained equilibrated polymer configurations using a coarse-grained model, and then investigated the spatially inhomogeneous chain scission process due to the passage of the ions. The number average molecular weight, weight average molecular weight and the polydispersity were calculated as a function of track radius, scission probability within the ion track and irradiation fluence. Finally we compared our results with a numerical implementation of a model for random homogeneous degradation. (C) 2010 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.nimb.2010.05.097"],["dc.identifier.isi","000282301100088"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18835"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.publisher.place","Amsterdam"],["dc.relation.conference","15th International Conference of the Radiation Effects in Insulators"],["dc.relation.eventlocation","ITALY"],["dc.relation.issn","0168-583X"],["dc.title","Monte Carlo study of molecular weight distribution changes induced by degradation of ion beam irradiated polymers"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Acta Physiologica"],["dc.bibliographiccitation.volume","216"],["dc.contributor.author","Terwitte, L."],["dc.contributor.author","Kizina, K."],["dc.contributor.author","Mueller, M."],["dc.date.accessioned","2018-11-07T10:17:30Z"],["dc.date.available","2018-11-07T10:17:30Z"],["dc.date.issued","2016"],["dc.identifier.isi","000372285400300"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41238"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1748-1716"],["dc.relation.issn","1748-1708"],["dc.title","Quantitative redox imaging in complex preparations by dual-laser based excitation ratiometric 2-photon microscopy"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","211"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Annals of Forest Research"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Müller, M."],["dc.contributor.author","Gailing, Oliver"],["dc.date.accessioned","2020-05-13T11:51:27Z"],["dc.date.available","2020-05-13T11:51:27Z"],["dc.date.issued","2018"],["dc.description.abstract","Northern red oak (Quercus rubra L.) is widely distributed in the eastern United States and southeastern Canada. It has also been introduced to Europe, where it has become an economically important plantation species now. Despite growing genomic resources, the number of available EST-SSR (expressed sequence tag – simple sequence repeat) markers for Q. rubra is still limited. Here, we used existing sequence information to provide a new set of EST-SSRs for northern red oak. In total, we report 20 polymorphic EST-SSRs, for which performance was evaluated in three Q. rubra populations from different regions in Michigan. We further tested the transferability of these markers to six additional oak species of section Lobatae (Quercus ellipsoidalis E.J. Hill, and Quercus georgiana M.A. Curtis) and Quercus (Quercus robur L., Quercus alba L., Quercus pedunculiflora K. Koch, and Quercus petraea (Matt.) Liebl.), as well as to European beech (Fagus sylvatica L.). The reported markers can be used in future population genetic studies."],["dc.identifier.doi","10.15287/afr.2018.1191"],["dc.identifier.scopus","2-s2.0-85060734156"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65322"],["dc.identifier.url","http://www.scopus.com/inward/record.url?eid=2-s2.0-85060734156&partnerID=MN8TOARS"],["dc.language.iso","en"],["dc.relation.eissn","1844-8135"],["dc.relation.issn","2065-2445"],["dc.relation.orgunit","Abteilung Forstgenetik und Forstpflanzenzüchtung"],["dc.title","Characterization of 20 new EST-SSR markers for northern red oak (Quercus rubra L.) and their transferability to Fagus sylvatica L. and six oak species of section Lobatae and Quercus"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","150"],["dc.bibliographiccitation.issue","1-3"],["dc.bibliographiccitation.journal","Toxicology"],["dc.bibliographiccitation.lastpage","151"],["dc.bibliographiccitation.volume","164"],["dc.contributor.author","Schulz, Thomas G."],["dc.contributor.author","Ruhnau, P."],["dc.contributor.author","Mueller, M."],["dc.contributor.author","Bunger, J."],["dc.contributor.author","Ellie-hausen, H. J."],["dc.contributor.author","Hallier, Ernst"],["dc.date.accessioned","2018-11-07T08:52:57Z"],["dc.date.available","2018-11-07T08:52:57Z"],["dc.date.issued","2001"],["dc.identifier.isi","000169888500479"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22289"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Sci Ireland Ltd"],["dc.publisher.place","Clare"],["dc.relation.issn","0300-483X"],["dc.title","Lack of correlation between CYP2A6 genotype and smoking habits"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","114"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Experimental Cell Research"],["dc.bibliographiccitation.lastpage","127"],["dc.bibliographiccitation.volume","303"],["dc.contributor.author","Mueller, M."],["dc.contributor.author","Mironov, Sergej L."],["dc.contributor.author","Ivannikov, M. V."],["dc.contributor.author","Schmidt, J."],["dc.contributor.author","Richter, Diethelm W."],["dc.date.accessioned","2018-11-07T08:27:46Z"],["dc.date.available","2018-11-07T08:27:46Z"],["dc.date.issued","2005"],["dc.description.abstract","Two-photon microscopy of rhodamine 123-labeled mitochondria revealed that mitochondria of neurons cultured from mouse respiratory center form functionally coupled, dynamically organized aggregates such as chains and clusters, while single mitochondria were rarely seen. Mitochondrial chain structures predominate in dendrites, while irregularly shaped mitochondrial clusters are mostly found in the soma. Both types of mitochondrial structures showed chaotic Brownian motions and the mitochondrial chains also revealed well-directed movements. The latter dislocations were arrested upon mitochondrial depolarization or blockade of mitochondrial ATP synthesis. Depolymerization of microtubules by colchicine or nocodazole or inhibition of protein phosphatases by calyculin A disrupted mitochondrial chains and the mitochondria accumulated in the soma. Forskolin and IBMX reversibly blocked directed movements of mitochondria, but did not affect their overall spatial distribution. Thus, protein phosphorylation seems to control both mitochondrial transport and organization. Protein phosphorylation downstream of enhanced cytosolic CAMP levels apparently regulates the transition from motile to non-motile mitochondria, while phosphorylation resulting from inhibition of types 1 and 2A protein phosphatases massively disturbs mitochondrial organization. The complex phosphorylation processes seem to control the close interaction of mitochondria and cytoskeleton which may guarantee that mitochondria are immobilized at energetic hot spots and rearranged in response to changes in local energy demands. (C) 2004 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.yexcr.2004.09.025"],["dc.identifier.isi","000226111600011"],["dc.identifier.pmid","15572032"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/16270"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Inc"],["dc.relation.issn","0014-4827"],["dc.title","Mitochondrial organization and motility probed by two-photon microscopy in cultured mouse brainstem neurons"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","4937"],["dc.bibliographiccitation.issue","13"],["dc.bibliographiccitation.journal","Macromolecules"],["dc.bibliographiccitation.lastpage","4944"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Cavallo, Anna"],["dc.contributor.author","Mueller, M."],["dc.contributor.author","Binder, Kurt"],["dc.date.accessioned","2018-11-07T11:13:02Z"],["dc.date.available","2018-11-07T11:13:02Z"],["dc.date.issued","2008"],["dc.description.abstract","Using Monte Carlo simulations of the bond fluctuation model, we study the formation of micelles in a confined mixture of asymmetric AB-diblock copolymers and homopolymers. The composition of the sphere-forming AB-diblock copolymers is f(A) = 1/8. The mixture is confined into a thin film. The film surfaces attract the minority component of the diblock with strength, epsilon(W). To efficiently sample the micelle size distribution and establish equilibrium between the surface and the bulk, we work in the semigrandcanonical ensemble, i.e. at fixed density and fixed chemical potential difference between the two types of chains, choosing a large incompatibility chi N similar or equal to 100 (strong segregation regime). The composition of the mixture is controlled by the chemical potential difference, delta mu = mu(cop) - mu(hom), between copolymers and homopolymers. We,study the morphology as a function of the surface interaction, epsilon(W), and the chemical potential, delta mu. Only in a limited regime of parameters-i.e., in the vicinity of the adsorption transition of the minority component at the surface and slightly below the critical micelle concentration in the bulk-surface micelles are formed. We characterize the shape of the adsorbed micelles by the tensor of gyration and radial density profiles."],["dc.identifier.doi","10.1021/ma800262f"],["dc.identifier.isi","000257366200057"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53802"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Chemical Soc"],["dc.relation.issn","0024-9297"],["dc.title","Monte Carlo simulation of a homopolymer-copolymer mixture interacting with a surface: Bulk versus surface micelles and brush formation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","R128"],["dc.bibliographiccitation.journal","Naunyn-Schmiedeberg s Archives of Pharmacology"],["dc.bibliographiccitation.lastpage","R129"],["dc.bibliographiccitation.volume","371"],["dc.contributor.author","Mueller, M."],["dc.contributor.author","Schettgen, T."],["dc.contributor.author","Bunger, J."],["dc.contributor.author","Hallier, Ernst"],["dc.contributor.author","Angerer, J."],["dc.date.accessioned","2018-11-07T08:29:33Z"],["dc.date.available","2018-11-07T08:29:33Z"],["dc.date.issued","2005"],["dc.identifier.isi","000229046800536"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/16680"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.conference","46th Spring Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und Toxikologie"],["dc.relation.eventlocation","Mainz, GERMANY"],["dc.relation.issn","0028-1298"],["dc.title","The human glutathione S-transferase T1 activity influences the N-2-methylvaline adduct levels after high occupational exposure to dimethyl sulphate"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Journal of Forest Research"],["dc.contributor.author","Burger, Katrin"],["dc.contributor.author","Müller, Markus"],["dc.contributor.author","Rogge, Martin"],["dc.contributor.author","Gailing, Oliver"],["dc.date.accessioned","2021-08-12T07:46:12Z"],["dc.date.available","2021-08-12T07:46:12Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract Slavonian oaks ( Quercus robur subsp. slavonica (Gáyer) Mátyás) originating from Croatia have been cultivated in Germany mainly in the Münsterland region of North Rhine-Westphalia since the second half of the nineteenth century. Compared to indigenous pedunculate oak stands in Germany, they are characterised by their late bud burst, but also by their excellent bole shape and faster height growth. Previously, Slavonian pedunculate oaks (= late flushing oaks) were mainly studied at chloroplast (cp) DNA markers in order to determine their geographical origin. The origin of the material is probably the Sava lowland between Zagreb and Belgrade. In the present study, the aim was to genetically differentiate between indigenous Quercus robur and Slavonian oak stands using nuclear DNA markers. For this purpose, we used 20 nuclear Simple Sequence Repeats (nSSRs). A total of 37 pedunculate oak stands (mean: 18.6 samples per population with an age of 95 to 210 years) were examined, of which 21 were characterized as Slavonian late flushing oaks and three stands for which the Slavonian origin was not clear. Maternally inherited chloroplast markers were analysed earlier in all 37 stands to validate their geographic origin. We found that the stands of native pedunculate oaks and Slavonian pedunculate oaks are represented by two genetic clusters which are weakly differentiated. Slavonian oaks (N a  = 9.85, A r  = 8.689, H o  = 0.490, H e  = 0.540) showed similar levels of genetic variation as native oak stands (N a  = 7.850, A r  = 7.846, H o  = 0.484, H e  = 0.526). Differences in growth and phenology and low but consistent genetic differentiation between groups suggest that both taxa represent different ecotypes with specific local adaptations, which are perhaps separated by less overlapping flowering phenologies. The nuclear microsatellite markers in combination with the cpDNA markers are suitable to differentiate between Slavonian and local oak stands."],["dc.description.abstract","Abstract Slavonian oaks ( Quercus robur subsp. slavonica (Gáyer) Mátyás) originating from Croatia have been cultivated in Germany mainly in the Münsterland region of North Rhine-Westphalia since the second half of the nineteenth century. Compared to indigenous pedunculate oak stands in Germany, they are characterised by their late bud burst, but also by their excellent bole shape and faster height growth. Previously, Slavonian pedunculate oaks (= late flushing oaks) were mainly studied at chloroplast (cp) DNA markers in order to determine their geographical origin. The origin of the material is probably the Sava lowland between Zagreb and Belgrade. In the present study, the aim was to genetically differentiate between indigenous Quercus robur and Slavonian oak stands using nuclear DNA markers. For this purpose, we used 20 nuclear Simple Sequence Repeats (nSSRs). A total of 37 pedunculate oak stands (mean: 18.6 samples per population with an age of 95 to 210 years) were examined, of which 21 were characterized as Slavonian late flushing oaks and three stands for which the Slavonian origin was not clear. Maternally inherited chloroplast markers were analysed earlier in all 37 stands to validate their geographic origin. We found that the stands of native pedunculate oaks and Slavonian pedunculate oaks are represented by two genetic clusters which are weakly differentiated. Slavonian oaks (N a  = 9.85, A r  = 8.689, H o  = 0.490, H e  = 0.540) showed similar levels of genetic variation as native oak stands (N a  = 7.850, A r  = 7.846, H o  = 0.484, H e  = 0.526). Differences in growth and phenology and low but consistent genetic differentiation between groups suggest that both taxa represent different ecotypes with specific local adaptations, which are perhaps separated by less overlapping flowering phenologies. The nuclear microsatellite markers in combination with the cpDNA markers are suitable to differentiate between Slavonian and local oak stands."],["dc.identifier.doi","10.1007/s10342-021-01395-8"],["dc.identifier.pii","1395"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88642"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation.eissn","1612-4677"],["dc.relation.issn","1612-4669"],["dc.title","Genetic differentiation of indigenous (Quercus robur L.) and late flushing oak stands (Q. robur L. subsp. slavonica (Gáyer) Mátyás) in western Germany (North Rhine-Westphalia)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Naunyn-Schmiedeberg s Archives of Pharmacology"],["dc.bibliographiccitation.volume","369"],["dc.contributor.author","Mueller, M."],["dc.contributor.author","Schettgen, T."],["dc.contributor.author","Bunger, J."],["dc.contributor.author","Hallier, Ernst"],["dc.contributor.author","Angerer, J."],["dc.date.accessioned","2018-11-07T10:50:53Z"],["dc.date.available","2018-11-07T10:50:53Z"],["dc.date.issued","2004"],["dc.format.extent","R140"],["dc.identifier.isi","000220592800559"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48754"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.conference","45th Spring Meeting of the German-Society-for-Experimental-and-Clinical-Pharmacology-and-Toxicology"],["dc.relation.eventlocation","Mainz, GERMANY"],["dc.relation.issn","0028-1298"],["dc.title","Influence of the human glutathione S-transferase T1 activity on the N-2-hydroxyethylvaline adduct levels in non-smokers and smokers"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","PII S0306-4522(01)00498-5"],["dc.bibliographiccitation.firstpage","313"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Neuroscience"],["dc.bibliographiccitation.lastpage","328"],["dc.bibliographiccitation.volume","109"],["dc.contributor.author","Mueller, M."],["dc.contributor.author","Brockhaus, J."],["dc.contributor.author","Ballanyi, K."],["dc.date.accessioned","2018-11-07T10:33:33Z"],["dc.date.available","2018-11-07T10:33:33Z"],["dc.date.issued","2002"],["dc.description.abstract","The role of ATP in anoxic activation of ATP-sensitive K+ (K-ATP) channels was studied in dorsal vagal neurons of mouse brainstem slices. In the whole-cell configuration, cyanide-induced chemical anoxia evoked within 10 s a 300-pA outward current that gave rise to a hyperpolarization of 24 mV. These responses were mimicked by nitrogen-aerated saline, rotenone or diazoxide and abolished by tolbutamide. The cyanide-induced hyperpolarization was due to activation of 70 pS K-ATP channels that were half-maximally blocked by 5 muM internal ATP, Dialyzing the cells with either 1, 20 or 0 mM ATP did not, however, affect the time to onset, the kinetics or the magnitude of the cyanide-induced hyperpolarization. Impairment of ATP consumption by ouabain, vanadate or reduced temperature had no effect either. Thus, anoxia-induced activation of these K-ATP channels cannot be explained by a fall of cellular ATP or a concomitant rise of ADP. Anoxia-related changes of the actin cytoskeleton or the composition of the plasma membrane are also not likely to be involved, as cytochalasin D did not affect the cyanide-evoked hyperpolarization and phosphatidylinositol 4,5-bisphosphate failed to decrease the ATP sensitivity of single K-ATP channels. Finally, because of a lack of effects of reduced/oxidized glutathione and the oxidase blocker diphenyliodonium on the cyanide-induced hyperpolarization, cellular redox state does not appear to be involved. Our results indicate that despite a high sensitivity to ATP in excised patches, anoxic activation of K-ATP channels is independent of cellular ATP. Rather the ATP block seems to be removed as a consequence of impaired mitochondrial function. (C) 2002 IBRO. Published by Elsevier Science Ltd. All rights reserved."],["dc.identifier.doi","10.1016/S0306-4522(01)00498-5"],["dc.identifier.isi","000174078600010"],["dc.identifier.pmid","11801367"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44638"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0306-4522"],["dc.title","ATP-independent anoxic activation of ATP-sensitive K+ channels in dorsal vagal neurons of juvenile mice in situ"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]