Sennhenn-Kirchner, Sabine

[["dc.bibliographiccitation.firstpage","313"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Lasers in Medical Science"],["dc.bibliographiccitation.lastpage","320"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Sennhenn-Kirchner, Sabine"],["dc.contributor.author","Schwarz, Peter"],["dc.contributor.author","Schliephake, Henning"],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Brunner, Edgar"],["dc.contributor.author","Borg-von Zepelin, Margarete"],["dc.date.accessioned","2018-06-25T07:08:41Z"],["dc.date.available","2018-06-25T07:08:41Z"],["dc.date.issued","2009"],["dc.description.abstract","The different forms of superficial and systemic candidiasis are often associated with biofilm formation on surfaces of host tissues or medical devices. The biofilm formation of Candida spp., in general, necessitates significantly increased amounts of antifungal agents for therapy. Often the therapeutic effect is doubtful. A 5-day biofilm model with oral Candida isolates was established according to Chandra et al. (J Dent Res 80:903-908, 2001) on glass and titanium surfaces and was modified by Sennhenn-Kirchner et al. (Z Zahnärztl Implantol 3:45-51, 2007) to investigate different aspects unanswered in the field of dentistry. In this model, the efficacy of erbium:yttrium-aluminium-garnet (Er:YAG) light (2940 nm, 100 mJ, 10 Hz, 300 micros pulsed mode applied for 80 s) and diode laser light (810 nm, 1 W, continuous wave mode applied for 20 s with four repetitions after 30 s pauses each) was evaluated and compared to untreated controls. The photometric evaluation of the samples was completed by observations on morphological changes of yeast cells grown in the biofilm. Compared to the untreated controls Candida cells grown in mature in vitro biofilms were significantly reduced by both wavelengths investigated. Comparison between the different methods of laser treatment additionally revealed a significantly greater effect of the Er:YAG over the diode laser. Scanning electron microscopy findings proved that the diode laser light was effective in direct contact mode. In contrast, in the areas without direct contact, the fungal cells were left almost unchanged. The Er:YAG laser damaged the fungal cells to a great extent wherever it was applied."],["dc.identifier.doi","10.1007/s10103-008-0561-3"],["dc.identifier.pmid","18458992"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3106"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15129"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.eissn","1435-604X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Decontamination efficacy of erbium:yttrium–aluminium–garnet and diode laser light on oral Candida albicans isolates of a 5-day in vitro biofilm model"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","157"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","164"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Sennhenn-Kirchner, Sabine"],["dc.contributor.author","Freund, Friederike"],["dc.contributor.author","Grundmann, Sven"],["dc.contributor.author","Martin, Alexios"],["dc.contributor.author","Borg-von Zepelin, Margarete"],["dc.contributor.author","Christiansen, Hans"],["dc.contributor.author","Wolff, Hendrik"],["dc.contributor.author","Jacobs, Hans-Georg"],["dc.date.accessioned","2019-07-09T11:53:03Z"],["dc.date.available","2019-07-09T11:53:03Z"],["dc.date.issued","2008"],["dc.description.abstract","The present investigation evaluates the dental care situation of patients with head and neck cancer before and after radiotherapy. The situations of these patients in 1993 and 2005 were compared to detect similarities, differences and developments. In the years 1993 and 2005, 37 and 36 patients, respectively, with head and neck cancer treated by the local departments of otorhinolaryngology and of radiotherapy were examined consecutively according to their aftercare appointments. Time points of radiotherapy treatment of the patients evaluated in 1993 varied from 1984 to 1993. The patients evaluated in 2005 had received radiotherapy between 1998 and 2005. Therefore the applied radiotherapeutic regimen differed not only between the two groups of patients, but also within each group. The information for these investigations was provided anonymously. It was evaluated with descriptive statistics. The evaluation of the data shows distinct differences with respect to preventive and therapeutic dental care measures. In 2005, 35 out of 36 patients (97.2%) had a dental consultation before radiotherapy (1993, 65%). All 27 dentate patients (100%) obtained a splint for fluoride application (1993, none). 29% fewer edentulous patients were seen than in 1993. The number of teeth destroyed decreased from 19.2% (1993) to 7.8% in 2005. Mycoses due to Candida spp. and chronic failures in wound healing were rare (5.5%). In the course of the 12 years, prophylactic measures, such as the application of splints for fluoride treatment, were intensified. However, concepts for the dental care of patients undergoing radiotherapy, especially following the radiation, should be widened to avoid ruined teeth and long delayed wound healings."],["dc.identifier.doi","10.1007/s00784-008-0229-1"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6772"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60330"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Springer"],["dc.publisher.place","Berlin/Heidelberg"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Dental therapy before and after radiotherapy–an evaluation on patients with head and neck malignancies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]