Klumpp, Stefan

[["dc.bibliographiccitation.artnumber","e71527"],["dc.bibliographiccitation.journal","eLife"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Codutti, Agnese"],["dc.contributor.author","Charsooghi, Mohammad A"],["dc.contributor.author","Cerdá-Doñate, Elisa"],["dc.contributor.author","Taïeb, Hubert M"],["dc.contributor.author","Robinson, Tom"],["dc.contributor.author","Faivre, Damien"],["dc.contributor.author","Klumpp, Stefan"],["dc.date.accessioned","2022-09-01T09:51:21Z"],["dc.date.available","2022-09-01T09:51:21Z"],["dc.date.issued","2022"],["dc.description.abstract","Swimming microorganisms often experience complex environments in their natural habitat. The same is true for microswimmers in envisioned biomedical applications. The simple aqueous conditions typically studied in the lab differ strongly from those found in these environments and often exclude the effects of small volume confinement or the influence that external fields have on their motion. In this work, we investigate magnetically steerable microswimmers, specifically magnetotactic bacteria, in strong spatial confinement and under the influence of an external magnetic field. We trap single cells in micrometer-sized microfluidic chambers and track and analyze their motion, which shows a variety of different trajectories, depending on the chamber size and the strength of the magnetic field. Combining these experimental observations with simulations using a variant of an active Brownian particle model, we explain the variety of trajectories by the interplay between the wall interactions and the magnetic torque. We also analyze the pronounced cell-to-cell heterogeneity, which makes single-cell tracking essential for an understanding of the motility patterns. In this way, our work establishes a basis for the analysis and prediction of microswimmer motility in more complex environments."],["dc.description.sponsorship"," Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659"],["dc.description.sponsorship"," Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659"],["dc.description.sponsorship","BMBF and Max Planck Society"],["dc.description.sponsorship","IMPRS on Multiscale Biosystems"],["dc.identifier.doi","10.7554/eLife.71527"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113943"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","2050-084X"],["dc.rights.uri","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Interplay of surface interaction and magnetic torque in single-cell motion of magnetotactic bacteria in microfluidic confinement"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e1007548"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","PLoS Computational Biology"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Codutti, Agnese"],["dc.contributor.author","Bente, Klaas"],["dc.contributor.author","Faivre, Damien"],["dc.contributor.author","Klumpp, Stefan"],["dc.contributor.editor","Igoshin, Oleg A"],["dc.date.accessioned","2020-12-10T18:42:04Z"],["dc.date.available","2020-12-10T18:42:04Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1371/journal.pcbi.1007548"],["dc.identifier.eissn","1553-7358"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17116"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77793"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.relation.orgunit","Fakultät für Physik"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Chemotaxis in external fields: Simulations for active magnetic biological matter"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","eLife"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Bente, Klaas"],["dc.contributor.author","Mohammadinejad, Sarah"],["dc.contributor.author","Charsooghi, Mohammad Avalin"],["dc.contributor.author","Bachmann, Felix"],["dc.contributor.author","Codutti, Agnese"],["dc.contributor.author","Lefèvre, Christopher T"],["dc.contributor.author","Klumpp, Stefan"],["dc.contributor.author","Faivre, Damien"],["dc.date.accessioned","2020-12-10T18:48:08Z"],["dc.date.available","2020-12-10T18:48:08Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.7554/eLife.47551"],["dc.identifier.eissn","2050-084X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/79027"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","High-speed motility originates from cooperatively pushing and pulling flagella bundles in bilophotrichous bacteria"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in robotics and AI"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Codutti, Agnese"],["dc.contributor.author","Bachmann, Felix"],["dc.contributor.author","Faivre, Damien"],["dc.contributor.author","Klumpp, Stefan"],["dc.date.accessioned","2020-12-10T18:46:52Z"],["dc.date.available","2020-12-10T18:46:52Z"],["dc.date.issued","2018"],["dc.description.abstract","The field of synthetic microswimmers, micro-robots moving in aqueous environments, has evolved significantly in the last years. Micro-robots actuated and steered by external magnetic fields are of particular interest because of the biocompatibility of this energy source and the possibility of remote control, features suited for biomedical applications. While initial work has mostly focused on helical shapes, the design space under consideration has widened considerably with recent works, opening up new possibilities for optimization of propellers to meet specific requirements. Understanding the relation between shape on the one hand and targeted actuation and steerability on the other hand requires an understanding of their propulsion behavior. Here we propose hydrodynamic simulations for the characterization of rigid micropropellers of any shape, actuated by rotating external magnetic fields. The method consists of approximating the propellers by rigid clusters of spheres. We characterize the influence of model parameters on the swimming behavior to identify optimal simulation parameters using helical propellers as a test system. We then explore the behavior of randomly shaped propellers that were recently characterized experimentally. The simulations show that the orientation of the magnetic moment with respect to the propeller's internal coordinate system has a strong impact on the propulsion behavior and has to be known with a precision of ≤ 5° to predict the propeller's velocity-frequency curve. This result emphasizes the importance of the magnetic properties of the micropropellers for the design of desired functionalities for potential biomedical applications, and in particular the importance of their orientation within the propeller's structure."],["dc.identifier.doi","10.3389/frobt.2018.00109"],["dc.identifier.eissn","2296-9144"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78575"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","2296-9144"],["dc.rights","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Bead-Based Hydrodynamic Simulations of Rigid Magnetic Micropropellers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","174102"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","Applied Physics Letters"],["dc.bibliographiccitation.volume","118"],["dc.contributor.author","Bachmann, Felix"],["dc.contributor.author","Giltinan, Joshua"],["dc.contributor.author","Codutti, Agnese"],["dc.contributor.author","Klumpp, Stefan"],["dc.contributor.author","Sitti, Metin"],["dc.contributor.author","Faivre, Damien"],["dc.date.accessioned","2021-09-01T06:42:16Z"],["dc.date.available","2021-09-01T06:42:16Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1063/5.0045454"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89020"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-455"],["dc.relation.eissn","1077-3118"],["dc.relation.issn","0003-6951"],["dc.title","Opportunities and utilization of branching and step-out behavior in magnetic microswimmers with a nonlinear response"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","567a"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Biophysical Journal"],["dc.bibliographiccitation.volume","112"],["dc.contributor.author","Klumpp, Stefan"],["dc.contributor.author","Lefevre, Christopher"],["dc.contributor.author","Landau, Livnat"],["dc.contributor.author","Codutti, Agnese"],["dc.contributor.author","Bennet, Mathieu"],["dc.contributor.author","Faivre, Damien"],["dc.date.accessioned","2020-12-10T14:22:43Z"],["dc.date.available","2020-12-10T14:22:43Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.bpj.2016.11.3052"],["dc.identifier.issn","0006-3495"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71706"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Magneto-Aerotaxis: Bacterial Motility in Magnetic Fields"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]