Großkopf, Birgit

[["dc.bibliographiccitation.firstpage","206"],["dc.bibliographiccitation.journal","Osteoporosis International"],["dc.bibliographiccitation.lastpage","207"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Chovancova, Hana"],["dc.contributor.author","Pavlova, S."],["dc.contributor.author","Toman, Robert"],["dc.date.accessioned","2018-11-07T08:43:46Z"],["dc.date.available","2018-11-07T08:43:46Z"],["dc.date.issued","2010"],["dc.identifier.isi","000277299400446"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20053"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","London"],["dc.relation.conference","IOF World Congress on Osteoporosis/10th European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis"],["dc.relation.eventlocation","Florence, ITALY"],["dc.relation.issn","0937-941X"],["dc.title","CHANGES IN FEMORAL BONE STRUCTURE OF RATS AFTER AN INTRAPERITONEAL ADMINISTRATION OF CADMIUM"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S179"],["dc.bibliographiccitation.journal","Osteoporosis International"],["dc.bibliographiccitation.lastpage","S180"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Vondrakova, Maria"],["dc.contributor.author","Bauerova, Maria"],["dc.date.accessioned","2018-11-07T09:55:28Z"],["dc.date.available","2018-11-07T09:55:28Z"],["dc.date.issued","2006"],["dc.identifier.isi","000245980600155"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36746"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Artington"],["dc.relation.eventlocation","Washington, DC"],["dc.relation.issn","0937-941X"],["dc.title","Prevalence of femoral osteoporosis in medieval humans from Dubovany cemetery (Western Slovakia): Macroscopic and microscopic examination"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","109"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Environmental Science and Health, Part B"],["dc.bibliographiccitation.lastpage","116"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Kovacova, Veronika"],["dc.contributor.author","Mondockova, Vladimira"],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Kolesarova, Adriana"],["dc.contributor.author","Martiniakova, Monika"],["dc.date.accessioned","2021-04-14T08:30:13Z"],["dc.date.available","2021-04-14T08:30:13Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1080/03601234.2020.1852054"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83151"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1532-4109"],["dc.relation.issn","0360-1234"],["dc.title","Cyanogenic glycoside amygdalin influences functions of human osteoblasts in vitro"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","167"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","ANATOMIA HISTOLOGIA EMBRYOLOGIA-JOURNAL OF VETERINARY MEDICINE SERIES C"],["dc.bibliographiccitation.lastpage","170"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Vondrakova, Maria"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Fabis, M."],["dc.date.accessioned","2018-11-07T09:42:41Z"],["dc.date.available","2018-11-07T09:42:41Z"],["dc.date.issued","2006"],["dc.description.abstract","The purpose of this investigation was to study in detail compact bone tissue microscopic structure of adult cows and pigs with an emphasis to find an adequate key for the species identification. Altogether 18 femurs were analysed. Each of the bones was sectioned at the smallest breadth of their diaphysis. Specimens were prepared using standard histological equipment, producing thin sections approximately 80-100 mu m thick. The qualitative differences between investigated species were examined in anterior, posterior, medial and lateral views of thin sections. The quantitative ones were counted using the specific computer software Scion Image. We measured the area, perimeter, minimal and maximal diameter of the Haversian canals, the Haversian systems and the vascular canals of primary osteons. After that a discriminant function analysis was used for the species identification. According to our results the basic structural pattern of femur diaphysis was primary vascular plexiform in both species. However, non-vascular bone tissue was identified in cows and resorption lacunae were found between the secondary osteons in pigs. The measured variables of the Haversian canals, the Haversian systems and the primary osteon's vascular canals were higher in most cases in cows. Classification functions for investigated species give a correct classification of 64.69% of cases. This percentage value can be increased by integrating conclusions from the qualitative analysis."],["dc.identifier.doi","10.1111/j.1439-0264.2005.00652.x"],["dc.identifier.isi","000237348200008"],["dc.identifier.pmid","16677211"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34013"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0340-2096"],["dc.title","Differences in femoral compact bone tissue microscopic structure between adult cows (Bos taurus) and pigs (Sus scrofa domestica)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","310"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","ANATOMIA HISTOLOGIA EMBRYOLOGIA-JOURNAL OF VETERINARY MEDICINE SERIES C"],["dc.bibliographiccitation.lastpage","315"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Ryban, L."],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Vondrakova, Maria"],["dc.contributor.author","Bauerova, Maria"],["dc.contributor.author","Fabis, M."],["dc.contributor.author","Chrenek, Peter"],["dc.date.accessioned","2018-11-07T09:08:08Z"],["dc.date.available","2018-11-07T09:08:08Z"],["dc.date.issued","2006"],["dc.description.abstract","The aim of this study was to investigate differences in compact bone tissue microstructure between New Zealand White transgenic rabbits with human blood clotting factor VIII gene and the non-transgenic ones. The transgene was under the transcriptional control of the whey acidic protein (WAP) promoter. Altogether, 42 femora were analysed. Specimens were prepared using standard histological equipment, producing thin sections approximately 80-100 mu m. Areas, perimeters, minimum and maximum diameters of vascular canals of primary osteons, Haversian canals and secondary osteons were measured. Our results indicate the basic structural pattern of the bone tissue was primary vascular longitudinal in both groups of rabbits. However, a fibrolamellar bone tissue was identified only in the transgenic rabbits. The measured variables of the vascular canals of the primary osteons, the Haversian canals and the secondary osteons were higher in transgenic rabbits in comparison with non-transgenic ones in most cases and the differences were often statistically significant (P < 0.01; P < 0.001). More significant differences were noticed in males (transgenic versus non-transgenic). However, it is not easy to find the real cause of the changes. Despite the fact that no hFVIII mRNA expression was found in the analysed bone of transgenic rabbits, we presume that the observed differences could be associated with transgenesis. In this article, we discuss possible associations between transgene integration as well as aneuploidy and/or observed microstructural changes in compact bone tissue."],["dc.identifier.doi","10.1111/j.1439-0264.2006.00690.x"],["dc.identifier.isi","000240401600007"],["dc.identifier.pmid","16968250"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25957"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0340-2096"],["dc.title","Comparative study of compact bone tissue microstructure between non-transgenic and transgenic rabbits with WAP-hFVIII gene construct"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","140"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","FOLIA BIOLOGICA"],["dc.bibliographiccitation.lastpage","144"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Chrenek, Peter"],["dc.contributor.author","Ryban, L."],["dc.contributor.author","Parkanyi, V."],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Vondrakova, Maria"],["dc.contributor.author","Bauerova, Maria"],["dc.date.accessioned","2018-11-07T08:38:59Z"],["dc.date.available","2018-11-07T08:38:59Z"],["dc.date.issued","2005"],["dc.description.abstract","Bone tissue microstructure of femur was investigated in transgenic New Zealand White rabbits with human factor VIII gene. Altogether 42 bones (24 from transgenic rabbits and 18 from non-transgenic ones) were analysed. Specimens were prepared using standard histological equipment, producing thin sections of approximately 80-100 mu m. For histomorphometrical analysis areas, perimeters, minimum and maximum diameters of osteons' vascular canals and of osteons were measured. We found out that the basic structural pattern of femoral bone tissue was primary vascular longitudinal in both groups of rabbits. However, a new type of the bone tissue - fibrolamellar - was identified only in the transgenic rabbits. The measured variables of the osteons' vascular canals were higher in transgenic individuals in comparison with the nontransgenie ones (except for maximal diameter) and the differences were statistically significant (P < 0.05; P < 0.01). We suppose that the observed differences could be associated with transgenesis. In an effort to explain these differences we compared the cytogenctic profile of bone marrow cells between transgenic and nontransgenic rabbits. A significantly higher rate of aneuploidy was observed in c-metaphase spreads of transgenic individuals as compared to non-transgenic ones (P < 0.001). Despite the fact that no hFVIII mRNA expression was found in the femur of transgenic rabbits, we discussed an association of transgene integration into the genome and microstructural changes in the bone. In any case, the results indicate that transgenesis can also produce changes in other tissues than in the target ones."],["dc.identifier.isi","000233052100004"],["dc.identifier.pmid","16285207"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18880"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Inst Molecular Genetics"],["dc.relation.issn","0015-5500"],["dc.title","Changes of femoral bone tissue microstructure in transgenic rabbits"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S192"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Bone"],["dc.bibliographiccitation.lastpage","S193"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Vondrakova, Maria"],["dc.contributor.author","Bauerova, Maria"],["dc.date.accessioned","2018-11-07T11:01:39Z"],["dc.date.available","2018-11-07T11:01:39Z"],["dc.date.issued","2007"],["dc.identifier.isi","000247426100189"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51195"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.publisher.place","New york"],["dc.relation.conference","17th Scientific Meeting of the International-Bone-and-Mineral-Society"],["dc.relation.eventlocation","Montreal, CANADA"],["dc.relation.issn","8756-3282"],["dc.title","Age-related bone loss and frequency of femoral osteoporosis in medieval population from the territory of Slovakia"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","American Journal of Physical Anthropology"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Bauerova, Maria"],["dc.contributor.author","Toman, Robert"],["dc.date.accessioned","2018-11-07T08:33:40Z"],["dc.date.available","2018-11-07T08:33:40Z"],["dc.date.issued","2009"],["dc.format.extent","202"],["dc.identifier.isi","000263442701121"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17634"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-liss"],["dc.publisher.place","Hoboken"],["dc.relation.conference","78th Annual Meeting of the American-Association-of-Physical-Anthropologists"],["dc.relation.eventlocation","Chicago, IL"],["dc.relation.issn","0002-9483"],["dc.title","Effect of cadmium on femoral bone structure in rats: an animal model for human exposure to this metal"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","409"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal of Veterinary Medical Science"],["dc.bibliographiccitation.lastpage","411"],["dc.bibliographiccitation.volume","69"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Vondrakova, Maria"],["dc.contributor.author","Bauerova, Maria"],["dc.date.accessioned","2018-11-07T11:03:43Z"],["dc.date.available","2018-11-07T11:03:43Z"],["dc.date.issued","2007"],["dc.description.abstract","Histological sections of femoral diaphysis from adult sheep were investigated in this study. The qualitative characteristics in microstructure of the compact bone were examined in anterior, posterior, medial and lateral views; the quantitative ones were assessed using the software Scion Image. Areas, perimeters, minimum and maximum diameters of the Haversian canals, the Haversian systems and the primary osteons' vascular canals were measured. Our results indicate that ovine diaphysis of the femur is occupied mainly with primary vascular plexiform (laminar, fibrolamellar) tissue. In addition, irregular and dense Haversian bone tissues were observed. All measured variables disposed lower values in comparison with other artiodactyls (cattle and pig)."],["dc.identifier.doi","10.1292/jvms.69.409"],["dc.identifier.isi","000246726100012"],["dc.identifier.pmid","17485930"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51674"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Soc Vet Sci"],["dc.relation.issn","0916-7250"],["dc.title","Histological analysis of ovine compact bone tissue"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","American Journal of Physical Anthropology"],["dc.contributor.author","Martiniakova, Monika"],["dc.contributor.author","Omelka, Radoslav"],["dc.contributor.author","Grosskopf, Birgit"],["dc.contributor.author","Jancova, Alena"],["dc.contributor.author","Bauerova, Maria"],["dc.date.accessioned","2018-11-07T11:05:52Z"],["dc.date.available","2018-11-07T11:05:52Z"],["dc.date.issued","2007"],["dc.format.extent","166"],["dc.identifier.isi","000244656500460"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52165"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.issn","0002-9483"],["dc.title","Variability in osteon and Haversian canal sizes between medieval and recent human populations from Slovakia."],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]