Hofmann, Anna Maria

[["dc.bibliographiccitation.firstpage","28"],["dc.bibliographiccitation.issue","S327"],["dc.bibliographiccitation.journal","Proceedings of the International Astronomical Union"],["dc.bibliographiccitation.lastpage","33"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Manrique, S. J. González"],["dc.contributor.author","Denker, C."],["dc.contributor.author","Kuckein, C."],["dc.contributor.author","Yabar, A. Pastor"],["dc.contributor.author","Collados, M."],["dc.contributor.author","Verma, M."],["dc.contributor.author","Balthasar, H."],["dc.contributor.author","Diercke, A."],["dc.contributor.author","Fischer, C. E."],["dc.contributor.author","Gömöry, P."],["dc.contributor.author","González, N. Bello"],["dc.contributor.author","Schlichenmaier, R."],["dc.contributor.author","Armas, M. Cubas"],["dc.contributor.author","Berkefeld, T."],["dc.contributor.author","Feller, A."],["dc.contributor.author","Hoch, S."],["dc.contributor.author","Hofmann, A."],["dc.contributor.author","Lagg, A."],["dc.contributor.author","Nicklas, H."],["dc.contributor.author","Suárez, D. Orozco"],["dc.contributor.author","Schmidt, D."],["dc.contributor.author","Schmidt, W."],["dc.contributor.author","Sigwarth, M."],["dc.contributor.author","Sobotka, M."],["dc.contributor.author","Solanki, S. K."],["dc.contributor.author","Soltau, D."],["dc.contributor.author","Staude, J."],["dc.contributor.author","Strassmeier, K. G."],["dc.contributor.author","Volkmer, R."],["dc.contributor.author","von der Lühe, O."],["dc.contributor.author","Waldmann, T."],["dc.date.accessioned","2020-12-10T15:22:25Z"],["dc.date.available","2020-12-10T15:22:25Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1017/S1743921317000278"],["dc.identifier.eissn","1743-9221"],["dc.identifier.issn","1743-9213"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73394"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Flows along arch filaments observed in the GRIS ‘very fast spectroscopic mode’"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","31"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Bone and Mineral Metabolism"],["dc.bibliographiccitation.lastpage","39"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Hoffmann, D. B."],["dc.contributor.author","Sehmisch, S."],["dc.contributor.author","Hofmann, A. M."],["dc.contributor.author","Eimer, C."],["dc.contributor.author","Komrakova, M."],["dc.contributor.author","Saul, D."],["dc.contributor.author","Wassmann, M."],["dc.contributor.author","Stürmer, K. M."],["dc.contributor.author","Tezval, M."],["dc.date.accessioned","2018-10-08T06:30:06Z"],["dc.date.accessioned","2020-06-15T06:44:32Z"],["dc.date.available","2018-10-08T06:30:06Z"],["dc.date.available","2020-06-15T06:44:32Z"],["dc.date.issued","2016"],["dc.description.abstract","We investigated the combinatorial effects of whole-body vertical vibration (WBVV) with the primarily osteoanabolic parathyroid hormone (PTH) and the mainly antiresorptive strontium ranelate (SR) in a rat model of osteoporosis. Ovariectomies were performed on 76 three-month-old Sprague-Dawley rats (OVX, n = 76; NON-OVX, n = 12). After 8 weeks, the ovariectomized rats were divided into 6 groups. One group (OVX + PTH) received daily injections of PTH (40 µg/kg body weight/day) for 6 weeks. Another group (OVX + SR) was fed SR-supplemented chow (600 mg/kg body weight/day). Three groups (OVX + VIB, OVX + PTH + VIB, and OVX + SR + VIB) were treated with WBVV twice a day at 70 Hz for 15 min. Two groups (OVX + PTH + VIB, OVX + SR + VIB) were treated additionally with PTH and SR, respectively. The rats were killed at 14 weeks post-ovariectomy. The lumbar vertebrae and femora were removed for biomechanical and morphological assessment. PTH produced statistically significant improvements in biomechanical and structural properties, including bone mineral density (BMD) and trabecular bone quality. In contrast, SR treatment exerted mild effects, with significant effects in cortical thickness only. SR produced no significant improvement in biomechanical properties. WBVV as a single or an adjunctive therapy produced no significant improvements. In conclusion, vibration therapy administered as a single or dual treatment had no significant impact on bones affected by osteoporosis. PTH considerably improved bone quality in osteoporosis cases and is superior to treatment with SR."],["dc.identifier.doi","10.1007/s00774-016-0736-0"],["dc.identifier.pmid","26825660"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66239"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1435-5604"],["dc.title","Comparison of parathyroid hormone and strontium ranelate in combination with whole-body vibration in a rat model of osteoporosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","187"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Acta Neuropathologica Communications"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Hofmann, Anna"],["dc.contributor.author","Wrede, Arne"],["dc.contributor.author","Jürgens-Wemheuer, Wiebke M."],["dc.contributor.author","Schulz-Schaeffer, Walter J."],["dc.date.accessioned","2022-01-11T14:06:09Z"],["dc.date.available","2022-01-11T14:06:09Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract In sporadic Creutzfeldt–Jakob disease (sCJD), the pathological changes appear to be restricted to the central nervous system. Only involvement of the trigeminal ganglion is widely accepted. The present study systematically examined the involvement of peripheral ganglia in sCJD utilizing the currently most sensitive technique for detecting prions in tissue morphologically. The trigeminal, nodose, stellate, and celiac ganglia, as well as ganglia of the cervical, thoracic and lumbar sympathetic trunk of 40 patients were analyzed with the paraffin-embedded tissue (PET)-blot method. Apart from the trigeminal ganglion, which contained protein aggregates in five of 19 prion type 1 patients, evidence of prion protein aggregation was only found in patients associated with type 2 prions. With the PET-blot, aggregates of prion protein type 2 were found in all trigeminal (17/17), in some nodose (5 of 7) and thoracic (3 of 6) ganglia, as well as in a few celiac (4 of 19) and lumbar (1 of 5) ganglia of sCJD patients. Whereas aggregates of both prion types may spread to dorsal root ganglia, more CNS-distant ganglia seem to be only involved in patients accumulating prion type 2. Whether the prion type association is due to selection by prion type-dependent replication, or due to a prion type-dependent property of axonal spread remains to be resolved in further studies."],["dc.description.abstract","Abstract In sporadic Creutzfeldt–Jakob disease (sCJD), the pathological changes appear to be restricted to the central nervous system. Only involvement of the trigeminal ganglion is widely accepted. The present study systematically examined the involvement of peripheral ganglia in sCJD utilizing the currently most sensitive technique for detecting prions in tissue morphologically. The trigeminal, nodose, stellate, and celiac ganglia, as well as ganglia of the cervical, thoracic and lumbar sympathetic trunk of 40 patients were analyzed with the paraffin-embedded tissue (PET)-blot method. Apart from the trigeminal ganglion, which contained protein aggregates in five of 19 prion type 1 patients, evidence of prion protein aggregation was only found in patients associated with type 2 prions. With the PET-blot, aggregates of prion protein type 2 were found in all trigeminal (17/17), in some nodose (5 of 7) and thoracic (3 of 6) ganglia, as well as in a few celiac (4 of 19) and lumbar (1 of 5) ganglia of sCJD patients. Whereas aggregates of both prion types may spread to dorsal root ganglia, more CNS-distant ganglia seem to be only involved in patients accumulating prion type 2. Whether the prion type association is due to selection by prion type-dependent replication, or due to a prion type-dependent property of axonal spread remains to be resolved in further studies."],["dc.identifier.doi","10.1186/s40478-021-01286-4"],["dc.identifier.pii","1286"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/97837"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-507"],["dc.relation.eissn","2051-5960"],["dc.title","Prion type 2 selection in sporadic Creutzfeldt–Jakob disease affecting peripheral ganglia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]