Balcarek, Peter

[["dc.bibliographiccitation.firstpage","261"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","ACTA ORTHOPAEDICA BELGICA"],["dc.bibliographiccitation.lastpage","265"],["dc.bibliographiccitation.volume","74"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Sawallich, Tobias"],["dc.contributor.author","Losch, Andreas"],["dc.contributor.author","Stuermer, Klaus Michael"],["dc.contributor.author","Frosch, Karl-Heinz"],["dc.date.accessioned","2018-11-07T11:16:16Z"],["dc.date.available","2018-11-07T11:16:16Z"],["dc.date.issued","2008"],["dc.description.abstract","Loss of knee extension after reconstruction of the anterior cruciate ligament may occur due to a neo-proliferative fibrous nodule located anterolateral to the tibial tunnel, termed cyclops syndrome. This nodule occurs usually within the early postoperative period and results in diminished knee extension due to impingement on the intercondylar notch. We report a case of a 24-year-old female patient with an uncommon delayed-onset loss of knee extension due to a cyclops syndrome four years after anterior cruciate ligament reconstruction."],["dc.identifier.isi","000256232500019"],["dc.identifier.pmid","18564486"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54545"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Acta Medica Belgica"],["dc.relation.issn","0001-6462"],["dc.title","Delayed cyclops syndrome : Symptomatic extension block four years after anterior cruciate ligament reconstruction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Archives of Orthopaedic and Trauma Surgery"],["dc.contributor.author","Fluegel, Julian"],["dc.contributor.author","Zimmermann, Felix"],["dc.contributor.author","Gebhardt, Sebastian"],["dc.contributor.author","Milinkovic, Danko Dan"],["dc.contributor.author","Balcarek, Peter"],["dc.date.accessioned","2022-09-01T09:51:31Z"],["dc.date.available","2022-09-01T09:51:31Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1007/s00402-022-04541-y"],["dc.identifier.pii","4541"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113986"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","1434-3916"],["dc.rights.uri","https://www.springer.com/tdm"],["dc.title","Combined distal femoral osteotomy and tibial tuberosity distalization is effective in patients presenting with patellar instability and patellofemoral pain due to patella alta and femoral malalignment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","189"],["dc.bibliographiccitation.journal","Experimental Neurology"],["dc.bibliographiccitation.lastpage","197"],["dc.bibliographiccitation.volume","271"],["dc.contributor.author","Muth, Ingrid E."],["dc.contributor.author","Zschuentzsch, Jana"],["dc.contributor.author","Kleinschnitz, Konstanze"],["dc.contributor.author","Wrede, Arne"],["dc.contributor.author","Gerhardt, Ellen"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Schreiber-Katz, Olivia"],["dc.contributor.author","Zierz, Stephan"],["dc.contributor.author","Dalakas, Marinas C."],["dc.contributor.author","Voll, Reinhard E."],["dc.contributor.author","Schmidt, Jens"],["dc.date.accessioned","2018-11-07T09:52:13Z"],["dc.date.available","2018-11-07T09:52:13Z"],["dc.date.issued","2015"],["dc.description.abstract","Inflammation is associated with protein accumulation in IBM, but precise mechanisms are elusive. The \"alarmin\" HMGB1 is upregulated in muscle inflammation. Its receptor RAGE is crucial for S-amyloid-associated neurodegeneration. Relevant signaling via HMGB1/RAGE is expected in IBM pathology. By real-time-PCR, mRNA-expression levels of HMGB1 and RAGE were upregulated in muscle biopsies of patients with IBM and PM, but not in muscular dystrophy or non-myopathic controls. By immunohistochemistry, both molecules displayed the highest signal in IBM, where they distinctly co-localized to intra-fiber accumulations of beta-amyloid and neurofilament/tau. In these fibers, identification of phosphorylated Erk suggested that relevant downstream activation is present upon HMGB1 signaling via RAGE. Protein expressions of HMGB1, RAGE, Erk and phosphorylated Erk were confirmed by Western blot. In a well established cell-culture model for pro-inflammatory cell-stress, exposure of human muscle-cells to 1L-1 beta + IFN-gamma induced cytoplasmic translocation of HMGB1 and subsequent release as evidenced by ELISA. Upregulation of RAGE on the cell surface was demonstrated by immunocytochemistry and flow-cytometry. Recombinant HMGB1 was equally potent as IL-1 beta + IFN-gamma in causing amyloid-accumulation and cell-death, and both were abrogated by the HMGB1-blocker BoxA. The findings strengthen the concept of unique interactions between degenerative and inflammatory mechanisms and suggest that HMGB1/RAGE signaling is a critical pathway in IBM pathology. (C) 2015 Elsevier Inc. All rights reserved."],["dc.description.sponsorship","Association Francaise contre les Myopathies (AFM) [13512, 14952]"],["dc.identifier.doi","10.1016/j.expneurol.2015.05.023"],["dc.identifier.isi","000362627200020"],["dc.identifier.pmid","26048613"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36071"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","1090-2430"],["dc.relation.issn","0014-4886"],["dc.title","HMGB1 and RAGE in skeletal muscle inflammation: Implications for protein accumulation in inclusion body myositis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2308"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Knee Surgery Sports Traumatology Arthroscopy"],["dc.bibliographiccitation.lastpage","2314"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Oberthuer, Swantje"],["dc.contributor.author","Hopfensitz, Stephanie"],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Walde, Tim Alexander"],["dc.contributor.author","Wachowski, Martin Michael"],["dc.contributor.author","Schuettrumpf, Jan Philipp"],["dc.contributor.author","Stuermer, Klaus Michael"],["dc.date.accessioned","2018-11-07T09:34:48Z"],["dc.date.available","2018-11-07T09:34:48Z"],["dc.date.issued","2014"],["dc.description.abstract","The purpose of this study was to identify the risk factors for recurrent lateral patellar dislocations and to incorporate those factors into a patellar instability severity score. Sixty-one patients [male/female 35/26; median age 19 years (range 9-51 years)] formed the study group for this investigation. Within the study group, 40 patients experienced a patellar redislocation within 24 months after the primary dislocation, whereas 21 patients, who were assessed after a median follow-up of 37 months (range 24-60 months), had not experienced a subsequent episode of lateral patellar instability. In all patients, age at the time of the primary dislocation, gender, the affected body side, body mass index, bilateral instability, physical activity according to Baecke's questionnaire, the grade of trochlear dysplasia, patellar height, tibial tuberosity-trochlear groove (TT-TG) distance, and patellar tilt were assessed. The odds ratio (OR) of each factor with regard to the patellar redislocation was calculated using contingency tables. Based on these data, a \"patellar instability severity score\" was calculated. The patellar instability severity score has six factors: age, bilateral instability, the severity of trochlear dysplasia, patella alta, TT-TG distance, and patellar tilt; the total possible score is seven. Reapplying this score to the study population revealed a median score of 4 points (range 2-7) for those patients with an early episode of patellar redislocation and a median score of 3 points (range 1-6) for those without a redislocation (p = 0.0004). The OR for recurrent dislocations was 4.88 (95 % CI 1.57-15.17) for the patients who scored 4 or more points when compared with the patients who scored 3 or fewer points (p = 0.0064). Based on the individual patient data, the patellar instability severity score allows an initial risk assessment for experiencing a recurrent patellar dislocation and might help differentiate between responders and non-responders to conservative treatment after primary lateral patellar instability."],["dc.identifier.doi","10.1007/s00167-013-2650-5"],["dc.identifier.isi","000342468800007"],["dc.identifier.pmid","24005331"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32253"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1433-7347"],["dc.relation.issn","0942-2056"],["dc.title","Which patellae are likely to redislocate?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","415"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.lastpage","420"],["dc.bibliographiccitation.volume","79"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Walde, Tim Alexander"],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Schüttrumpf, Jan P."],["dc.contributor.author","Wachowski, Martin M."],["dc.contributor.author","Stürmer, Klaus M."],["dc.contributor.author","Frosch, Karl-Heinz"],["dc.date.accessioned","2021-06-01T10:49:35Z"],["dc.date.available","2021-06-01T10:49:35Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1016/j.ejrad.2010.06.042"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86346"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","0720-048X"],["dc.title","Patellar dislocations in children, adolescents and adults: A comparative MRI study of medial patellofemoral ligament injury patterns and trochlear groove anatomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","195"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Annals of Anatomy - Anatomischer Anzeiger"],["dc.bibliographiccitation.lastpage","199"],["dc.bibliographiccitation.volume","194"],["dc.contributor.author","Wachowski, Martin Michael"],["dc.contributor.author","Walde, Tim Alexander"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Schuettrumpf, Jan Philipp"],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Stauffenberg, Caspar"],["dc.contributor.author","Frosch, Karl-Heinz"],["dc.contributor.author","Fiedler, Christoph"],["dc.contributor.author","Fanghaenel, Jochen"],["dc.contributor.author","Kubein-Meesenburg, Dietmar"],["dc.contributor.author","Naegerl, Hans"],["dc.date.accessioned","2018-11-07T09:15:19Z"],["dc.date.available","2018-11-07T09:15:19Z"],["dc.date.issued","2012"],["dc.description.abstract","A novel class of total knee replacement (AEQUOS G1) is introduced which features a unique design of the articular surfaces. Based on the anatomy of the human knee and differing from all other prostheses, the lateral tibial \"plateau\" is convexly curved and the lateral femoral condyle is posteriorly shifted in relation to the medial femoral condyle. Under compressive forces the configuration of the articular surfaces of human knees constrains the relative motion of femur and tibia in flexion/extension. This constrained motion is equivalent to that of a four-bar linkage, the virtual 4 pivots of which are given by the centres of curvature of the articulating surfaces. The dimensions of the four-bar linkage were optimized to the effect that constrained motion of the total knee replacement (TKR) follows the flexional motion of the human knee in close approximation, particularly during gait. In pilot studies lateral X-ray pictures have demonstrated that AEQUOS G1 can feature the natural rollback in vivo. Rollback relieves the load of the patello-femoral joint and minimizes retropatellar pressure. This mechanism should reduce the prevalence of anterior knee pain. The articulating surfaces roll predominantly in the stance phase. Consequently sliding friction is replaced by the lesser rolling friction under load. Producing rollback should minimize material wear due to friction and maximize the lifetime of the prosthesis. To definitely confirm these theses one has to wait for the long term results. (C) 2011 Elsevier GmbH. All rights reserved."],["dc.identifier.doi","10.1016/j.aanat.2011.01.013"],["dc.identifier.isi","000304339900008"],["dc.identifier.pmid","21493053"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27655"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.relation.issn","0940-9602"],["dc.title","Total knee replacement with natural rollback"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3869"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Knee Surgery, Sports Traumatology, Arthroscopy"],["dc.bibliographiccitation.lastpage","3877"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Rehn, Stephan"],["dc.contributor.author","Howells, Nick R."],["dc.contributor.author","Eldridge, Jonathan D."],["dc.contributor.author","Kita, Keisuke"],["dc.contributor.author","Dejour, David"],["dc.contributor.author","Nelitz, Manfred"],["dc.contributor.author","Banke, Ingo J."],["dc.contributor.author","Lambrecht, Delphine"],["dc.contributor.author","Harden, Markus"],["dc.contributor.author","Friede, Tim"],["dc.date.accessioned","2020-12-10T14:09:50Z"],["dc.date.available","2020-12-10T14:09:50Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1007/s00167-016-4365-x"],["dc.identifier.eissn","1433-7347"],["dc.identifier.issn","0942-2056"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70574"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Results of medial patellofemoral ligament reconstruction compared with trochleoplasty plus individual extensor apparatus balancing in patellar instability caused by severe trochlear dysplasia: a systematic review and meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","232596712110104"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Orthopaedic Journal of Sports Medicine"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Zimmermann, Felix"],["dc.contributor.author","Milinkovic, Danko Dan"],["dc.contributor.author","Balcarek, Peter"],["dc.date.accessioned","2022-04-01T10:02:47Z"],["dc.date.available","2022-04-01T10:02:47Z"],["dc.date.issued","2021"],["dc.description.abstract","Background: Abnormal patellofemoral joint stress appears to have major relevance in a subgroup of patients with patellofemoral pain (PFP). Purpose: To evaluate whether patients with chronic PFP and trochlear dysplasia–induced patellofemoral joint malalignment benefit from a deepening trochleoplasty procedure with the aim of improving patellotrochlear congruence. Study Design: Case series; Level of evidence, 4. Methods: Included were 15 patients (male/female, 1/14; mean age, 30.3 years [range, 19-51 years]) with 8.8 years (range, 1-20 years) of chronic PFP and severe trochlear dysplasia. All patients underwent correction of patellotrochlear malalignment with deepening trochleoplasty and concomitant realignment procedures. The Kujala score and a numerical analog scale (0-10) for intensity of pain were used to assess symptoms preoperatively and at 12 and 24 months postoperatively. Pre- and postoperative magnetic resonance imaging (MRI) scans from the patients were compared with the MRI scans of age- and sex-matched controls regarding the patellotrochlear contact area and contact ratio, patellar tilt, patellotrochlear index, and lateral trochlear inclination (LTI) angle. Results: The Kujala score increased from a mean of 55 (range, 15-81) preoperatively to 82.5 (range, 53-98) after 12 months (95% CI, –42.56 to –12.37; P < .001) and to 84.2 (range, 59-99) after 24 months (95% CI, –44.29 to –14.11; P < .001). The intensity of PFP decreased from 5.7 (range, 3-10) preoperatively to 1.4 (range, 0-4) after 12 months (95% CI, 2.57 to 5.96; P < .001) and had a mean of 1.6 (range, 0-6) after 24 months (95% CI, 2.44 to 5.75; P < .001). Preoperatively, parameters in the study group indicated significant patellotrochlear malalignment, which improved and normalized (except for the LTI angle) postoperatively compared with the values of the control group ( P > .05). Conclusion: In a subgroup of patients with chronic PFP due to severe trochlear dysplasia, deepening trochleoplasty and concomitant realignment procedures significantly reduced pain and improved knee joint function while normalizing patellotrochlear congruence."],["dc.identifier.doi","10.1177/23259671211010404"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/106007"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","2325-9671"],["dc.relation.issn","2325-9671"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0/"],["dc.title","Outcomes After Deepening Trochleoplasty and Concomitant Realignment in Patients With Severe Trochlear Dysplasia With Chronic Patellofemoral Pain: Results at 2-Year Follow-up"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Archives of Orthopaedic and Trauma Surgery"],["dc.contributor.author","Schmidt, Sebastian"],["dc.contributor.author","Mengis, Natalie"],["dc.contributor.author","Rippke, Jules N."],["dc.contributor.author","Zimmermann, Felix"],["dc.contributor.author","Milinkovic, Danko D."],["dc.contributor.author","Balcarek, Peter"],["dc.date.accessioned","2021-04-14T08:29:14Z"],["dc.date.available","2021-04-14T08:29:14Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1007/s00402-021-03863-7"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82841"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1434-3916"],["dc.relation.issn","0936-8051"],["dc.title","Treatment of acquired patella baja by proximalization tibial tubercle osteotomy significantly improved knee joint function but overall patient-reported outcome measures remain diminished after two to four years of follow-up"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","263"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Zentralblatt für Chirurgie - Zeitschrift für Allgemeine Viszeral- Thorax- und Gefäßchirurgie"],["dc.bibliographiccitation.lastpage","266"],["dc.bibliographiccitation.volume","134"],["dc.contributor.author","Tezval, Mohammed"],["dc.contributor.author","Sehmisch, Stefan"],["dc.contributor.author","Dumont, C."],["dc.contributor.author","Frosch, Karl-Heinz"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Stuermer, Klaus-Michael"],["dc.date.accessioned","2018-11-07T08:29:46Z"],["dc.date.available","2018-11-07T08:29:46Z"],["dc.date.issued","2009"],["dc.description.abstract","Introduction: In the literature, an acute colonic pseudo-obstruction (Ogilvie's syndrome) is frequently observed as a complication after hip arthroplasty. It results in a massive colon dilatation without mechanical obstructions and can lead to a life-threatening colon perforation with a high mortality. Case Report: We report on a 81-year-old male patient who suffered from an acetabular fracture after falling down with a concomitant coxarthrosis at the same hip side. A total hip arthroplasty was performed using a Muller cap. Postoperatively, he developed an acute colonic pseudo-obstruction that was treated conservatively with multiple colonoscopic decompressions. The importance of prompt recognition, careful monitoring and appropriate management to reduce morbidity and mortality are supported by this case. Conclusion: Early diagnosis and colonoscopic decompressions play a key role in the therapy for Ogilvie's syndrome. In case of a failure of conservative treatment or peritonism, an early laparotomy and coecostomy are necessary."],["dc.identifier.doi","10.1055/s-0028-1098698"],["dc.identifier.isi","000267668600017"],["dc.identifier.pmid","19536723"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/16738"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh"],["dc.relation.issn","0044-409X"],["dc.title","Acute Colonic Pseudo-Obstruction (Ogilvie's Syndrome), a Life-Threatening Complication after Total Hip Replacement"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]