Balcarek, Peter

[["dc.bibliographiccitation.artnumber","952699"],["dc.bibliographiccitation.journal","Frontiers in Neurology"],["dc.bibliographiccitation.volume","13"],["dc.contributor.affiliation","Lemmer, D.; 1Department of Nephrology and Rheumatology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Schmidt, J.; 3Department of Neurology and Pain Treatment, Immanuel Klinik Rüdersdorf, University Hospital of the Brandenburg Medical School Theodor Fontane, Rüdersdorf bei Berlin, Germany"],["dc.contributor.affiliation","Kummer, K.; 5Department of Neurology, Neuromuscular Center, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Lemmer, B.; 6Department of Physics, Georg-August-University Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Wrede, A.; 7Department of Neuropathology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Seitz, C.; 8Department of Dermatology, Allergology and Venereology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Balcarek, P.; 9Department of Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Schwarze, K.; 1Department of Nephrology and Rheumatology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Müller, G. A.; 1Department of Nephrology and Rheumatology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Patschan, D.; 4Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, Rüdersdorf bei Berlin, Germany"],["dc.contributor.affiliation","Patschan, S.; 4Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, Rüdersdorf bei Berlin, Germany"],["dc.contributor.author","Lemmer, D."],["dc.contributor.author","Schmidt, J."],["dc.contributor.author","Kummer, K."],["dc.contributor.author","Lemmer, B."],["dc.contributor.author","Wrede, A."],["dc.contributor.author","Seitz, C."],["dc.contributor.author","Balcarek, P."],["dc.contributor.author","Schwarze, K."],["dc.contributor.author","Müller, G. A."],["dc.contributor.author","Patschan, D."],["dc.contributor.author","Patschan, S."],["dc.date.accessioned","2022-12-01T08:31:33Z"],["dc.date.available","2022-12-01T08:31:33Z"],["dc.date.issued","2022"],["dc.date.updated","2022-11-11T13:12:29Z"],["dc.description.abstract","Background and aim\r\n Inflammatory myopathies are heterogeneous in terms of etiology, (immuno)pathology, and clinical findings. Endothelial cell injury, as it occurs in DM, is a common feature of numerous inflammatory and non-inflammatory vascular diseases. Vascular regeneration is mediated by both local and blood-derived mechanisms, such as the mobilization and activation of so-called proangiogenic cells (PACs) or early endothelial progenitor cells (eEPCs). The current study aimed to evaluate parameters of eEPC integrity in dermatomyositis (DM), compared to necrotizing myopathy (NM) and to non-myopathic controls.\r\n \r\n \r\n Methods\r\n \r\n Blood samples from DM and NM patients were compared to non-myositis controls and analyzed for the following parameters: circulating CD133\r\n +\r\n /VEGFR-2\r\n +\r\n cells, number of colony-forming unit endothelial cells (CFU-ECs), concentrations of angiopoietin 1, vascular endothelial growth factor (VEGF), and CXCL-16. Muscle biopsies from DM and NM subjects underwent immunofluorescence analysis for CXCR6, nestin, and CD31 (PECAM-1). Finally, myotubes, derived from healthy donors, were stimulated with serum samples from DM and NM patients, subsequently followed by RT-PCR for the following candidates: IL-1β, IL-6, nestin, and CD31.\r\n \r\n \r\n \r\n Results\r\n \r\n Seventeen (17) DM patients, 7 NM patients, and 40 non-myositis controls were included. CD133\r\n +\r\n /VEGFR-2\r\n +\r\n cells did not differ between the groups. Both DM and NM patients showed lower CFU-ECs than controls. In DM, intramuscular CD31 abundances were significantly reduced, which indicated vascular rarefaction. Muscular CXCR6 was elevated in both diseases. Circulating CXCL-16 was higher in DM and NM in contrast, compared to controls. Serum from patients with DM but not NM induced a profound upregulation of mRNS expression of CD31 and IL-6 in cultured myotubes.\r\n \r\n \r\n \r\n Conclusion\r\n Our study demonstrates the loss of intramuscular microvessels in DM, accompanied by endothelial activation in DM and NM. Vascular regeneration was impaired in DM and NM. The findings suggest a role for inflammation-associated vascular damage in the pathogenesis of DM."],["dc.identifier.doi","10.3389/fneur.2022.952699"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118201"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-621"],["dc.relation.eissn","1664-2295"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Impairment of muscular endothelial cell regeneration in dermatomyositis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","673"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Knee Surgery Sports Traumatology Arthroscopy"],["dc.bibliographiccitation.lastpage","680"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Kuhn, Anke"],["dc.contributor.author","Weigel, Arwed"],["dc.contributor.author","Walde, Tim Alexander"],["dc.contributor.author","Ferlemann, Keno G."],["dc.contributor.author","Stuermer, Klaus-Michael"],["dc.contributor.author","Frosch, Karl-Heinz"],["dc.date.accessioned","2018-11-07T08:43:40Z"],["dc.date.available","2018-11-07T08:43:40Z"],["dc.date.issued","2010"],["dc.description.abstract","The purpose of this study was to analyze the impact of monopolar radiofrequency energy treatment on subchondral bone viability. The femoral grooves of six chinchilla bastard rabbits were exposed bilaterally to monopolar radiofrequency energy for 2, 4 and 8 s, creating a total of 36 defects. An intravital fluorescence bone-labeling technique characterized the process of subchondral bone mineralization within the 3 months following exposure to radiofrequency energy and was analyzed by widefield epifluorescence optical sectioning microscopy using an ApoTome. After 2 s of radiofrequency energy exposure, regular fluorescence staining of the subchondral bone was evident in all samples when compared to untreated areas. The depth of osteonecrosis after 4 and 8 s of radiofrequency energy treatment averaged 126 and 942 A mu m at 22 days (P < .05; P < .01). The 4 s treatment group showed no osteonecrosis after 44 days whereas the depth of osteonecrosis extended from 519 A mu m at 44 days (P < .01), to 281 A mu m at 66 days (P < .01) and to 133 A mu m at 88 days (P < .05) after 8 s of radiofrequency energy application. Though radiofrequency energy may induce transient osteonecrosis in the superficial zone of the subchondral bone, the results of this study suggest that post-arthroscopic osteonecrosis appears to be of only modest risk given the current clinical application in humans."],["dc.identifier.doi","10.1007/s00167-009-0949-z"],["dc.identifier.isi","000276722900019"],["dc.identifier.pmid","19838673"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/4232"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20025"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0942-2056"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Impact of monopolar radiofrequency energy on subchondral bone viability"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2251"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Knee Surgery Sports Traumatology Arthroscopy"],["dc.bibliographiccitation.lastpage","2256"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Rittstieg, Anne"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Walde, Tim Alexander"],["dc.contributor.author","Schuettrumpf, Jan Philipp"],["dc.contributor.author","Wachowski, Martin Michael"],["dc.contributor.author","Stuermer, Klaus-Michael"],["dc.contributor.author","Frosch, Karl-Heinz"],["dc.date.accessioned","2018-11-07T09:04:12Z"],["dc.date.available","2018-11-07T09:04:12Z"],["dc.date.issued","2012"],["dc.description.abstract","The aim of this study was to evaluate the clinical outcome and differences in anterior-posterior laxity of ACL reconstruction using a bioabsorbable interference screw for femoral graft fixation when compared to femoral bioabsorbable cross pin fixation. Clinical outcome was evaluated among 59 patients 1 year after arthroscopic ACL reconstruction with hamstrings graft in a prospective, non-randomised study. In 31 cases, femoral fixation of the graft was performed using a bioabsorbable interference screw. In 28 cases, two bioabsorbable cross pins were used for femoral fixation. Patients were evaluated using Tegner, Lysholm and Marshall scores, the visual analogue scale for pain and KT-1000 arthrometer measurement. No significant difference (P a parts per thousand yen 0.05) was observed at follow-up for the knee scores. The average Tegner score was 5.83 points (+/- 2.00) for the interference screw fixation and 5.83 points (+/- 1.24) for the cross pin fixation; the average Lysholm score was 93.58 (+/- 5.79) to 92.72 (+/- 6.34) points; and the average Marshall score 46.72 (+/- 2.4) to 47.30 (+/- 2.35) points. No significant difference was found for the visual analogue scale for pain. KT-1000 arthrometer measurement revealed a significant (P < 0.05) difference in the mean side-to-side anterior translation at all applied forces. At 67 N, the mean difference was 1.53 mm (+/- 1.24) in the interference screw group and 0.47 mm (+/- 1.18) in the cross pin group (P < 0.05). At 89 N, the mean differences were 1.85 mm (+/- 1.29) versus 0.59 mm (+/- 1.59), respectively, (P < 0.05), and maximum manual displacements were 2.02 mm (+/- 1.26) versus 1.22 mm (1.18; P < 0.05). In ACL reconstruction with hamstrings graft, similar clinical results are obtained for the use of bioabsorbable cross pins when compared to bioabsorbable interference screws for femoral fixation. Cross pin fixation was superior with regard to the anteroposterior laxity as measured with KT-1000."],["dc.identifier.doi","10.1007/s00167-011-1875-4"],["dc.identifier.isi","000310223100018"],["dc.identifier.pmid","22290125"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8788"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25063"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0942-2056"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Bioabsorbable interference screw versus bioabsorbable cross pins: influence of femoral graft fixation on the clinical outcome after ACL reconstruction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","326586"],["dc.bibliographiccitation.journal","BioMed Research International"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Oberthuer, Swantje"],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Schuettrumpf, Jan Philipp"],["dc.contributor.author","Stuermer, Klaus Michael"],["dc.date.accessioned","2018-11-07T09:46:15Z"],["dc.date.available","2018-11-07T09:46:15Z"],["dc.date.issued","2014"],["dc.description.abstract","The morphology of the vastus medialis obliquus (VMO) muscle in the anatomical setting of an unstable patella has not been described. Therefore, the purpose of this study was to investigate the morphological parameters of the VMO muscle that delineate its importance in the maintenance of patellofemoral joint stability. Eighty-two consecutive subjects were prospectively enrolled in this study. The groups were composed of thirty patients with an acute primary patellar dislocation, thirty patients with recurrent patellar dislocation, and twenty-two controls. Groups were adjusted according to sex, age, body mass index, and physical activity. Magnetic resonance imaging was used to measure the VMO cross-sectional area, muscle-fiber angulation, and the craniocaudal extent of the muscle in relation to the patella. No significant difference was found with respect to all measured VMO parameters between primary dislocation, recurrent dislocation, and control subjects with a trend noted for only the VMO cross-sectional area and the VMO muscle-fiber angulation. This finding is notable in that atrophy of the VMO has often been suggested to play an important role in the pathophysiology of an unstable patellofemoral joint."],["dc.identifier.doi","10.1155/2014/326586"],["dc.identifier.isi","000335831000001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11688"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34828"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Hindawi Publishing Corporation"],["dc.relation.issn","2314-6141"],["dc.relation.issn","2314-6133"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","Vastus Medialis Obliquus Muscle Morphology in Primary and Recurrent Lateral Patellar Instability"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","NP6; author reply NP6"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","The American journal of sports medicine"],["dc.bibliographiccitation.lastpage","7"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Balcarek, Peter"],["dc.date.accessioned","2019-07-09T11:53:48Z"],["dc.date.available","2019-07-09T11:53:48Z"],["dc.date.issued","2011-06-01"],["dc.identifier.doi","10.1177/0363546511409657"],["dc.identifier.fs","585933"],["dc.identifier.pmid","21636727"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8058"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60500"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1552-3365"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.mesh","Child"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Ligaments, Articular"],["dc.subject.mesh","Patellar Dislocation"],["dc.title","Medial patellofemoral ligament injury in children: letter."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2155"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Knee Surgery Sports Traumatology Arthroscopy"],["dc.bibliographiccitation.lastpage","2163"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Terwey, Annika"],["dc.contributor.author","Jung, Klaus"],["dc.contributor.author","Walde, Tim Alexander"],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Schuettrumpf, Jan Philipp"],["dc.contributor.author","Wachowski, Martin Michael"],["dc.contributor.author","Dathe, Henning"],["dc.contributor.author","Sturmer, Klaus Michael"],["dc.date.accessioned","2018-11-07T09:20:52Z"],["dc.date.available","2018-11-07T09:20:52Z"],["dc.date.issued","2013"],["dc.description.abstract","The geometry of the tibial plateau and its influence on the biomechanics of the tibiofemoral joint has gained increased significance. However, no quantitative data are available regarding the inclination of the medial and lateral tibial slope in patients with patellar instability. It was therefore the purpose of this study to evaluate tibial slope characteristics in patients with patellar dislocations and to assess the biomechanical effect of medial-to-lateral tibial slope asymmetry on lateral patellar instability. Medial and lateral tibial slope was measured on knee magnetic resonance images in 107 patients and in 83 controls. The medial-to-lateral tibial slope asymmetry was assessed as the intra-individual difference between the medial and lateral tibial plateau inclination considering severity of trochlear dysplasia. The effect of tibial slope asymmetry on femoral rotation was calculated by means of radian measure. Severity of trochlear dysplasia was significantly associated with an asymmetric inclination of the tibial plateau. Whereas the medial tibial slope showed identical values between controls and study patients (n.s.), lateral tibial plateau inclination becomes flatter with increasing severity of trochlear dysplasia (p < 0.01). Consequently, the intra-individual tibial slope asymmetry increased steadily (p < 0.01) and increased internal femoral rotation in 20A degrees and 90A degrees of knee flexion angles in patients with severe trochlear dysplasia (p < 0.01). In addition, the extreme values of internal femoral rotation were more pronounced in patients with patellar instability, whereas the extreme values of external femoral rotation were more pronounced in control subjects (p = 0.024). Data of this study indicate an association between tibial plateau configuration and internal femoral rotation in patients with lateral patellar instability and underlying trochlear dysplasia. Thereby, medial-to-lateral tibial slope asymmetry increased internal femoral rotation during knee flexion and therefore might aggravate the effect of femoral antetorsion in patients with patellar instability. III."],["dc.identifier.doi","10.1007/s00167-012-2247-4"],["dc.identifier.isi","000323502400031"],["dc.identifier.pmid","23096490"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10282"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28973"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0942-2056"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Influence of tibial slope asymmetry on femoral rotation in patients with lateral patellar instability"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","5470831"],["dc.bibliographiccitation.journal","Mediators of Inflammation"],["dc.contributor.author","Schmidt, Karsten"],["dc.contributor.author","Wienken, Magdalena"],["dc.contributor.author","Keller, Christian W."],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Münz, Christian"],["dc.contributor.author","Schmidt, Jens"],["dc.date.accessioned","2018-11-07T10:29:09Z"],["dc.date.available","2018-11-07T10:29:09Z"],["dc.date.issued","2017"],["dc.description.abstract","The pathology of inclusion body myositis (IBM) involves an inflammatory response and beta-amyloid deposits in muscle fibres. It is believed that MAP kinases such as the ERK signalling pathway mediate the inflammatory signalling in cells. Further, there is evidence that autophagic activity plays a crucial role in the pathogenesis of IBM. Using a well established in vitro model of IBM, the autophagic pathway, MAP kinases, and accumulation of beta-amyloid were examined. We demonstrate that stimulation of muscle cells with IL-1 beta and IFN-gamma led to an increased phosphorylation of ERK. The ERK inhibitor PD98059 diminished the expression of proinflammatory markers as well as the accumulation of beta-amyloid. In addition, IL-1 beta and IFN-gamma led to an increase of autophagic activity, upregulation of APP, and subsequent accumulation of beta-sheet aggregates. Taken together, the data demonstrate that the ERK pathway contributes to formation of beta-amyloid and regulation of autophagic activity in muscle cells exposed to proinflammatory cell stress. This suggests that ERK serves as an important mediator between inflammatory mechanisms and protein deposition in skeletal muscle and is a crucial element of the pathology of IBM."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2016"],["dc.identifier.doi","10.1155/2017/5470831"],["dc.identifier.isi","000394098400001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14140"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43582"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Hindawi Ltd"],["dc.relation.issn","1466-1861"],["dc.relation.issn","0962-9351"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","IL-1 beta-Induced Accumulation of Amyloid: Macroautophagy in Skeletal Muscle Depends on ERK"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1575"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Knee Surgery, Sports Traumatology, Arthroscopy"],["dc.bibliographiccitation.lastpage","1580"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Walde, Tim A."],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Schüttrumpf, Jan"],["dc.contributor.author","Wachowski, Martin M."],["dc.contributor.author","Stürmer, Klaus"],["dc.date.accessioned","2019-07-09T11:53:49Z"],["dc.date.available","2019-07-09T11:53:49Z"],["dc.date.issued","2011"],["dc.description.abstract","The purpose of this study was to investigate whether the femoral part of the medial patellofemoral ligament (MPFL) and its injury can be accurately assessed by standard knee arthroscopy in first-time patellar dislocations or whether preoperative MRI is required to determine injury location in patients where primary MPFL repair is attempted.Twelve patients with acute first-time dislocations and MRI-based injury of the femoral MPFL and ten patients with recurrent patellar dislocations underwent knee arthroscopy with the use of a 30-degree optic and standard antero-medial and antero-lateral portals. The femoral origin was marked with a cannula under lateral fluoroscopy. Arthroscopic findings of the location of the native femoral MPFL and its injury were compared to the results of MRI and mini-open exploration.In acute cases, the average time from primary patellar dislocation to MRI evaluation was 3 days (1–9 days), and the average time from MRI to surgery was 8 days (3–20 days). The native femoral origin of the MPFL was not visible in any of the chronic cases during arthroscopy. In addition, in all acute cases, arthroscopy failed to directly visualize injury of the femoral MPFL (0 of 12), but mini-open exploration confirmed injury in 11 of 12 patients. This means that arthroscopy was less accurate than MRI for the diagnosis of femoral MPFL injury (P < 0.05).The results of this study indicate the limitations of knee arthroscopy in identifying the femoral disruption of the MPFL, a crucial injury that occurs in patellar dislocations. Thus, if a primary MPFL repair is planned, determination of the site of repair should be based on the preoperative MRI.Diagnostic study of non-consecutive patients, Level III."],["dc.identifier.doi","10.1007/s00167-011-1775-7"],["dc.identifier.fs","583699"],["dc.identifier.pmid","22095485"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8080"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60504"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Springer"],["dc.publisher.place","Berlin/Heidelberg"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","MRI but not arthroscopy accurately diagnoses femoral MPFL injury in first-time patellar dislocations"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","73"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Strategies in Trauma and Limb Reconstruction"],["dc.bibliographiccitation.lastpage","79"],["dc.bibliographiccitation.volume","2009"],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Stürmer, Klaus Michael"],["dc.contributor.author","Schütze, Gunther"],["dc.contributor.author","Frosch, K.-H."],["dc.contributor.author","Schwallich, T."],["dc.contributor.author","Losch, A."],["dc.contributor.author","Walde, T."],["dc.contributor.author","Balcarek, P."],["dc.date.accessioned","2019-07-09T11:52:50Z"],["dc.date.available","2019-07-09T11:52:50Z"],["dc.date.issued","2009"],["dc.description.abstract","Ligament graft fixation with bioabsorbable interference screws is a standard procedure in cruciate ligament replacement. Previous screw designs may resorb incompletely, and can cause osteolysis and sterile cysts despite being implanted for several years. The aim of this study was to examine the in vivo degradation and biocompatibility of the new Milagro™ interference screw (Mitek, Norderstedt, Germany). The Milagro™ interference screw is made of 30% ß-TCP (TriCalcium phosphate) and 70% PLGA (Poly-lactic-co-glycolic acid). In the period between June 2005 and February 2006, 38 patients underwent graft fixation with Milagro™ screws in our hospital. Arthroscopic ACL reconstruction was performed using hamstring tendon grafts in all the patients. MR imaging was performed on 12 randomly selected patients out of the total of 38 at 3, 6 and 12 months after surgery. During the examination, the volume loss of the screw, tunnel enlargement, presence of osteolysis, fluid lines, edema and postoperative screw replacement by bone tissue were evaluated. There was no edema or signs of inflammation around the bone tunnels. At 3, 6 and 12 months, the tibial screws showed an average volume loss of 0, 8.1% (±7.9%) and 82.6% (±17.2%, P < 0.05), respectively. The femoral screws showed volume losses of 2.5% (±2.1%), 31.3% (±21.6%) and 92.02% (±6.3%, P < 0.05), respectively. The femoral tunnel enlargement was 47.4% (±43.8%) of the original bone tunnel volume after 12 months, and the mean tunnel volume of the tibial tunnel was −9.5% (±58.1%) compared to the original tunnel. Bone ingrowth was observed in all the patients. In conclusion, the resorption behaviour of the Milagro™ screw is closely linked to the graft healing process. The screws were rapidly resorbed after 6 months and, at 12 months, only the screw remnants were detectable. Moreover, the Milagro™ screw is biocompatible and osteoconductive, promoting bone ingrowth during resorption. Tunnel enlargement is not prevented in the first months but is reduced by bone ingrowth after 12 months."],["dc.identifier.doi","10.1007/s11751-009-0063-2"],["dc.identifier.fs","434403"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6036"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60290"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1828-8936"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Magnetic resonance imaging analysis of the bioabsorbable Milagro interference screw for graft fixation in anterior cruciate ligament reconstruction."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","160"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","The Open Orthopaedics Journal"],["dc.bibliographiccitation.lastpage","163"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","P. Schüttrumpf, Jan"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Sehmisch, Stephan"],["dc.contributor.author","Frosch, Stephan"],["dc.contributor.author","Wachowski, Martin M."],["dc.contributor.author","Stürmer, Klaus M."],["dc.contributor.author","Walde, Hans-Joachim"],["dc.contributor.author","Walde, Tim A."],["dc.date.accessioned","2019-07-09T11:53:26Z"],["dc.date.available","2019-07-09T11:53:26Z"],["dc.date.issued","2012"],["dc.description.abstract","Purpose: The objective of this prospective study was to evaluate the medium-term clinical and radiological results after navigated cementless implantation, without patella resurfacing, of a total knee endoprosthesis with tibial and femoral press-fit components, with a focus on survival rate and clinical outcome. The innovation is the non-cemented fixation together with the use of a navigation system. Scope and Methods: Sixty patients with gonarthrosis were included consecutively in this study. In all cases, the cementless Columbus total knee endoprosthesis with a coating out of pure titanium was implanted, using a navigation system. The Knee Society Score showed a statistically significant increase from 75 (± 21.26) before surgery to 180 (± 16.15) after a mean follow-up of 5.6 (± 0.25) years. The last radiological examination revealed no osteolysis. No radiolucent lines were seen at any time in the area of the femoral prosthetic components. In the tibial area, radiolucent lines were seen in 24.4 % of the cases, mostly in the distal uncoated part of the stem. During follow-up, no prosthesis had to be replaced because of aseptic loosening while in 2 cases revision surgery was necessary due to septic loosening and in 1 case due to unexplainable pain. Results and Conclusions: Navigated cementless implantation of the Columbus total knee endoprosthesis yielded good clinical and radiological results in the medium term. The excellent radiological osteointegration of the prosthetic components, coated with a microporous pure titanium layer and implanted with a press-fit technique, should be emphasized."],["dc.identifier.doi","10.2174/1874325001206010160"],["dc.identifier.fs","585932"],["dc.identifier.pmid","22550552"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7573"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60425"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Navigated Cementless Total Knee Arthroplasty - Medium-Term Clinical and Radiological Results"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]