Edelmann, Frank Thomas

[["dc.bibliographiccitation.firstpage","658"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","ESC Heart Failure"],["dc.bibliographiccitation.lastpage","666"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Schertz, Anna"],["dc.contributor.author","Herbeck Belnap, Birgit"],["dc.contributor.author","Chavanon, Mira‐Lynn"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.date.accessioned","2020-12-10T14:06:10Z"],["dc.date.available","2020-12-10T14:06:10Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1002/ehf2.12436"],["dc.identifier.eissn","2055-5822"],["dc.identifier.issn","2055-5822"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16561"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69805"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","Motivational interviewing can support physical activity in elderly patients with diastolic heart failure: results from a pilot study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2171"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Chemische Berichte"],["dc.bibliographiccitation.lastpage","2181"],["dc.bibliographiccitation.volume","125"],["dc.contributor.author","Wedler, Michael"],["dc.contributor.author","Knösel, Friederich"],["dc.contributor.author","Pieper, Ursula"],["dc.contributor.author","Stalke, Dietmar"],["dc.contributor.author","Edelmann, Frank T."],["dc.contributor.author","Amberger, Hanns-Dieter"],["dc.date.accessioned","2019-07-09T11:52:12Z"],["dc.date.available","2019-07-09T11:52:12Z"],["dc.date.issued","1992"],["dc.description.abstract","Anhydrous lanthanide trichlorides react with N-silylated sodium benzamidinates, Na[4-RC6H4C(NSiMe3)2], (1a-d), to give the monomeric, homoleptic lanthanide(III) benzamidinates [4-RC6H4C(NSiMe3)2]3Ln (2-23, R = H, MeO, CF3, Ph). The molecular structure of [4-MeOC6H4C(NSiMe3)2]3Pr (11) has been determined by X-ray diffraction. Absorption and emission measurements reveal that the three benzamidinate ligands produce an unusually large crystal field which is comparable with that of cyclopentadienyl."],["dc.identifier.doi","10.1002/cber.19921251003"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3349"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60112"],["dc.language.iso","de"],["dc.notes.intern","Merged from goescholar"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","540"],["dc.title","Sterische Cyclopentadienyl-Äquivalente in der Chemie der f-Elemente: Monomere, homoleptische Lanthanid(III)-tris[N,N-bis(trimethylsilyl)-benzamidinate]"],["dc.title.alternative","Steric Cyclopentadienyl Equivalents in f-Element Chemistry: Monomeric, Homoleptic Lanthanide(III) Tris[N,N-bis(trimethylsilyl)benzamidinates]"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","41"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","ESC Heart Failure"],["dc.bibliographiccitation.lastpage","45"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Edelmann, Frank"],["dc.date.accessioned","2019-07-09T11:41:23Z"],["dc.date.available","2019-07-09T11:41:23Z"],["dc.date.issued","2015"],["dc.description.abstract","Heart failure with preserved ejection fraction (HFpEF) is a major and growing public health problem. Epidemiologic studies demonstrated that heart failure (HF) can be clinically diagnosed in patients with normal or preserved left ventricular ejection fraction. These patients are therefore termed as having HFpEF. In the past, this was often called diastolic HF. Because of the permanent increase of the prevalence of HFpEF during the past decades, HFpEF now accounts for more than 50% of the total HF population. There are uncertainties and debates regarding the definition, diagnosis, and pathophysiology with the consequence that all outcome trials performed so far used criteria for inclusion and exclusion that were not consistent. These trials also failed to document improved prognosis. Recent smaller proof-of-concept or Phase II clinical trials investigating different pathophysiological approaches with substances such as the neprilysin inhibitor–angiotensin receptor blocker− combination (LCZ 696), ranolazine, or ivabradine were successful to improve biomarkers, haemodynamics, or functional capacity. Future trials will need to document whether also prognosis can be improved."],["dc.identifier.doi","10.1002/ehf2.12037"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12009"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58416"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Facts and numbers on epidemiology and pharmacological treatment of heart failure with preserved ejection fraction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1152"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","1159"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Bobenko, Anna"],["dc.contributor.author","Schoenrath, Felix"],["dc.contributor.author","Knierim, Jan H."],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Verheyen, Nicolas"],["dc.contributor.author","Mehra, Mandeep R."],["dc.contributor.author","Haykowsky, Mark"],["dc.contributor.author","Herrmann‐Lingen, Christoph"],["dc.contributor.author","Duvinage, André"],["dc.contributor.author","Pieske‐Kraigher, Elisabeth"],["dc.contributor.author","Halle, Martin"],["dc.contributor.author","Falk, Volkmar"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Edelmann, Frank"],["dc.date.accessioned","2020-12-10T14:06:16Z"],["dc.date.available","2020-12-10T14:06:16Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1002/ejhf.1431"],["dc.identifier.eissn","1879-0844"],["dc.identifier.issn","1388-9842"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16660"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69836"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","Exercise training in patients with a left ventricular assist device (Ex‐VAD): rationale and design of a multicentre, prospective, assessor‐blinded, randomized, controlled trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e000182"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Open Heart"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Seegers, Joachim"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Grüter, Timo"],["dc.contributor.author","Ammermann, Antje"],["dc.contributor.author","Weber-Krüger, Mark"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Gelbrich, Götz"],["dc.contributor.author","Binder, Lutz"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.contributor.author","Gröschel, Klaus"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Wachter, Rolf"],["dc.date.accessioned","2017-09-07T11:52:34Z"],["dc.date.available","2017-09-07T11:52:34Z"],["dc.date.issued","2015"],["dc.identifier.doi","10.1136/openhrt-2014-000182"],["dc.identifier.gro","3144967"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13598"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/2650"],["dc.notes.intern","Crossref Import"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","public"],["dc.relation.issn","2053-3624"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","Natriuretic peptides for the detection of paroxysmal atrial fibrillation"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","496"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Angewandte Chemie"],["dc.bibliographiccitation.lastpage","497"],["dc.bibliographiccitation.volume","101"],["dc.contributor.author","Recknagel, Anja"],["dc.contributor.author","Stalke, Dietmar"],["dc.contributor.author","Roesky, Herbert W."],["dc.contributor.author","Edelmann, Frank T."],["dc.date.accessioned","2019-07-09T11:52:02Z"],["dc.date.available","2019-07-09T11:52:02Z"],["dc.date.issued","1989"],["dc.identifier.doi","10.1002/ange.1761010428"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3290"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60073"],["dc.language.iso","de"],["dc.notes.intern","Merged from goescholar"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","540"],["dc.title","Reduktive Dimerisierung eines Phosphaalkins unter Komlexierung an Samarium"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","59"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","ESC Heart Failure"],["dc.bibliographiccitation.lastpage","74"],["dc.bibliographiccitation.volume","1"],["dc.contributor.author","Nolte, Kathleen"],["dc.contributor.author","Schwarz, Silja"],["dc.contributor.author","Gelbrich, Götz"],["dc.contributor.author","Mensching, Steffen"],["dc.contributor.author","Siegmund, Friederike"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Düngen, Hans-Dirk"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.contributor.author","Halle, Martin"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Edelmann, Frank"],["dc.date.accessioned","2019-07-09T11:41:03Z"],["dc.date.available","2019-07-09T11:41:03Z"],["dc.date.issued","2014"],["dc.description.abstract","Background The long-term effects of exercise training (ET) in diastolic dysfunction (DD) and heart failure with preserved ejection fraction (HFpEF) are unknown. The present study compared the long-term effects of ET on exercise capacity, diastolic function, and quality of life (QoL) in patients with DD vs. HFpEF. Methods A total of n=43 patients with asymptomatic DD (n=19) or HFpEF [DD and New York Heart Association (NYHA) ≥II, n=24] and left ventricular ejection fraction ≥50% performed a combined endurance/resistance training over 6months (2–3/week) on top of usual care. Cardiopulmonary exercise testing, echocardiography, and QoL were obtained at baseline and follow-up. Results Patients were 62±8 years old (37% female). In the HFpEF group, 67% of patients were in NYHA class II (33% in NYHA III). Exercise capacity (peak oxygen consumption, peak VO2) differed at baseline (DD 29.2±8.7mL/min/kg vs. HFpEF 17.8±4.6 mL/min/kg; P=0.004). After 6months, peak VO2 increased significantly (P<0.044) to 19.7±5.8 mL/min/kg in the HFpEF group and also in the DD group (to 32.8±8.5mL/min/kg; P<0.002) with no overall difference between the groups (P=0.217). E/e′ ratio (left ventricular filling index) decreased from 12.2±3.5 to 10.1±3.0 (P<0.002) in patients with HFpEFand also in patients with DD (10.7±3.1 vs. 9.5±2.3; P=0.03; difference between groups P=0.210). In contrast, left atrial volume index decreased in the HFpEF group (P<0.001) but remained stable within the DD group (difference between groups P=0.015). After 6 months, physical QoL (Minnesota living with heart failure Questionnaire, 36-item short form health survey), general health perception, and 9-item patient health questionnaire score only improved in HFpEF (P<0.05). In contrast, vitality improved in both groups (difference between groups P=0.708). Conclusion A structured 6 months ET programme effectively improves exercise capacity and diastolic function in patients with DD and overt HFpEF. Therefore, controlled lifestylemodification with physical activity is effective both in DD and HFpEF."],["dc.identifier.doi","10.1002/ehf2.12007"],["dc.identifier.fs","610857"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11651"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58349"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1879-0844"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Effects of long-term endurance and resistance training on diastolic function, exercise capacity, and quality of life in asymptomatic diastolic dysfunction vs. heart failure with preserved ejection fraction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","875"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","884"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Mayer, Felix"],["dc.contributor.author","Stahrenberg, Raoul"],["dc.contributor.author","Groeschel, Klaus"],["dc.contributor.author","Mostardt, Sarah"],["dc.contributor.author","Biermann, Janine"],["dc.contributor.author","Edelmann, Frank T."],["dc.contributor.author","Liman, Jan"],["dc.contributor.author","Wasem, Juergen"],["dc.contributor.author","Goehler, Alexander"],["dc.contributor.author","Wachter, R. Rolf"],["dc.contributor.author","Neumann, Anja"],["dc.date.accessioned","2018-11-07T09:17:18Z"],["dc.date.available","2018-11-07T09:17:18Z"],["dc.date.issued","2013"],["dc.description.abstract","Prolonged Holter monitoring of patients with cerebral ischemia increases the detection rate of paroxysmal atrial fibrillation (PAF); this leads to improved antithrombotic regimens aimed at preventing recurrent ischemic strokes. The aim of this study was to compare a 7-day-Holter monitoring (7-d-Holter) alone or in combination with prior selection via transthoracic echocardiography (TTE) to a standard 24-h-Holter using a cost-utility analysis. Lifetime cost, quality-adjusted life years (QALY), and incremental cost-effectiveness ratios (ICER) were estimated for a cohort of patients with acute cerebral ischemia and no contraindication to oral anticoagulation. A Markov model was developed to simulate the long-term course and progression of cerebral ischemia considering the different diagnostic algorithms (24-h-Holter, 7-d-Holter, 7-d-Holter after preselection by TTE). Clinical data for these algorithms were derived from the prospective observational Find-AF study (ISRCTN 46104198). Predicted lifelong discounted costs were 33,837 a,not sign for patients diagnosed by the 7-d-Holter and 33,852 a,not sign by the standard 24-h-Holter. Cumulated QALYs were 3.868 for the 7-d-Holter compared to 3.844 for the 24-h-Holter. The 7-d-Holter dominated the 24-h-Holter in the base-case scenario and remained cost-effective in extensive sensitivity analysis of key input parameter with a maximum of 8,354 a,not sign/QALY gained. Preselecting patients for the 7-d-Holter had no positive effect on the cost-effectiveness. A 7-d-Holter to detect PAF in patients with cerebral ischemia is cost-effective. It increases the detection which leads to improved antithrombotic regimens; therefore, it avoids recurrent strokes, saves future costs, and decreases quality of life impairment. Preselecting patients by TTE does not improve cost-effectiveness."],["dc.description.sponsorship","Medtronic"],["dc.identifier.doi","10.1007/s00392-013-0601-2"],["dc.identifier.isi","000327208800003"],["dc.identifier.pmid","23904073"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11170"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28131"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0692"],["dc.relation.issn","1861-0684"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Cost-effectiveness of 7-day-Holter monitoring alone or in combination with transthoracic echocardiography in patients with cerebral ischemia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Psycho-social medicine"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Romppel, Matthias"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Düngen, Hans-Dirk"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Grande, Gesine"],["dc.date.accessioned","2019-07-09T11:40:10Z"],["dc.date.available","2019-07-09T11:40:10Z"],["dc.date.issued","2013"],["dc.description.abstract","OBJECTIVE: General self-efficacy has been found to be an influential variable related to the adaptation to stress and chronic illness, with the General Self-Efficacy (GSE) Scale by Jerusalem and Schwarzer being a reliable and valid instrument to assess this disposition. The aim of this study was to construct and test a short form of this scale to allow for a more economical assessment of the construct. METHODS: The item characteristics of the original scale were assessed using an intercultural non-clinical sample (n=19,719). Six items with the highest coefficient of variation and good discrimination along the range of the trait were selected to build a short form of the instrument (GSE-6). Subsequently, the psychometric properties and the concurrent and predictive validity of the GSE-6 were tested in a longitudinal design with three measurements using a sample of patients with risk factors for heart failure (n=1,460). RESULTS: Cronbach's alpha for the GSE-6 was between .79 and .88. We found negative associations with symptoms of depression (-.35 and -.45), anxiety (-.35), and vital exhaustion (-.38) and positive associations with social support (.30), and mental health (.36). In addition, the GSE-6 score was positively associated with active problem-focused coping (.26) and distraction/self-encouragement (.25) and negatively associated with depressive coping (-.34). The baseline GSE-6 score predicted mental health and physical health after 28 months, even after controlling for the respective baseline score. The relative stability over twelve and 28 months was r=.50 and r=.60, respectively, while the mean self-efficacy score did not change over time. CONCLUSIONS: The six item short form of the GSE scale is a reliable and valid instrument that is useful for the economical assessment of general self-efficacy in large multivariate studies and for screening purposes."],["dc.description.abstract","Hintergrund: Die generalisierte Selbstwirksamkeit hat sich als einflussreiche Variable im Zusammenhang mit der Anpassung an stressreiche Situationen und chronische Erkrankungen gezeigt. Die Skala Generalisierte Selbstwirksamkeit (GSW) von Jerusalem und Schwarzer ist ein reliables und valides Instrument zur Erhebung dieser Disposition. Ziel der vorliegenden Studie war die Entwicklung und Prüfung einer Kurzform dieser Skala, um eine ökonomischere Erfassung des Konstrukts zu ermöglichen.Methoden: Die Itemmerkmale der Original-Skala wurden anhand der Daten einer interkulturellen, nicht-klinischen Stichprobe (n=19.719) bestimmt. Sechs Items mit dem höchsten Variationskoeffizienten und guter Diskrimination über den Merkmalsbereich wurden ausgewählt, um aus ihnen eine Kurzform des Instruments zusammenzustellen (GSW- 6). Anschließend wurden psychometrische Merkmale und die konkurrente und prädiktive Validität der GSW-6 in einem Längsschnittdesign mit drei Messzeitpunkten an einer Stichprobe von Patienten mit Risikofaktoren für eine Herzinsuffizienz geprüft (n=1.460). Ergebnisse: Cronbachs alpha für die GSW-6 lag zwischen .79 und .88. Wir fanden negative Zusammenhänge mit depressiven Symptomen (–.35 und –.45), Angstsymptomen (–.35), und vitaler Erschöpfung (–.38) sowie positive Zusammenhänge mit sozialer Unterstützung (.30) und psychischer Gesundheit (.36). Weiterhin hing der GSW-6-Score positiv mit aktivem problemorientiertem Coping (.26) und Ablenkung/Selbstaufbau (.25) sowie negativ mit depressiver Krankheitsverarbeitung (–.34) zusammen. Der GSW-6-Ausgangswert konnte die psychische und körperliche Gesundheit nach 28 Monaten, auch nach Kontrolle des jeweiligen Ausgangswertes, vorhersagen. Die relative Stabilität über zwölf bzw. 28 Monate betrug r=.50 und r=.60, während sich der mittlere Selbstwirksamkeitsscore im Zeitverlauf nicht änderte. Schlussfolgerungen: Die aus sechs Items bestehende Kurzform der GSW-Skala ist ein reliables und valides Instrument, das zur ökonomischen Erfassung der generalisierten Selbstwirksamkeit in großen multivariaten Studien und zum Einsatz als Screeninginstrument geeignet ist."],["dc.identifier.doi","10.3205/psm000091"],["dc.identifier.fs","592821"],["dc.identifier.pmid","23429426"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10719"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58105"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1860-5214"],["dc.rights","CC BY-NC-ND 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/3.0"],["dc.title","A short form of the General Self-Efficacy Scale (GSE-6): Development, psychometric properties and validity in an intercultural non-clinical sample and a sample of patients at risk for heart failure."],["dc.title.alternative","Eine Kurzform der Skala zur Generalisierten Selbstwirksamkeit (GSW-6):Entwicklung, psychometrische Merkmale und Validität in einerinterkulturellen nicht-klinischen Stichprobe und in einer Stichprobe vonHerzinsuffizienz-Risikopatienten"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e34351"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Lahno, Rosine"],["dc.contributor.author","Haase, Beatrice"],["dc.contributor.author","Weber-Krueger, Mark"],["dc.contributor.author","Seegers, Joachim"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Wohlfahrt, Janin"],["dc.contributor.author","Gelbrich, Götz"],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Kermer, Pawel"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Groeschel, Klaus"],["dc.contributor.author","Stahrenberg, Raoul"],["dc.date.accessioned","2017-09-07T11:48:54Z"],["dc.date.available","2017-09-07T11:48:54Z"],["dc.date.issued","2012"],["dc.description.abstract","Background and Purpose: Diagnosis of paroxysmal atrial fibrillation (AF) can be challenging, but it is highly relevant in patients presenting with sinus rhythm and acute cerebral ischemia. We aimed to evaluate prospectively whether natriuretic peptide levels and kinetics identify patients with paroxysmal AF. Methods: Patients with acute cerebral ischemia were included into the prospective observational Find-AF study. N-terminal pro brain-type natriuretic peptide (NT-proBNP), brain-type natriuretic peptide (BNP) and N-terminal pro atrial-type natriuretic peptide (NT-proANP) plasma levels were measured on admission, after 6 and 24 hours. Patients free from AF at presentation received 7 day Holter monitoring. We prospectively hypothesized that patients presenting in sinus rhythm with NT-proBNP>median were more likely to have paroxysmal AF than patients with NT-proBNPmedian (239 pg/ml), 17.9% had paroxysmal AF in contrast to 7.4% with NT-proBNP<239 pg/ml (p = 0.025). The ratio of early (0 h) to late (24 h) plasma levels of NT-proBNP showed no difference between both groups. For the detection of paroxysmal atrial fibrillation, BNP, NT-proBNP and NT-proANP at admission had an area under the curve in ROC analysis of 0.747 (0.663-0.831), 0.638 (0.531-0.744) and 0.663 (0.566-0.761), respectively. In multivariate analysis, BNP was the only biomarker to be independently predictive for paroxysmal atrial fibrillation. Conclusions: BNP is independently predictive of paroxysmal AF detected by prolonged ECG monitoring in patients with cerebral ischemia and may be used to effectively select patients for prolonged Holter monitoring."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2012"],["dc.identifier.doi","10.1371/journal.pone.0034351"],["dc.identifier.gro","3142549"],["dc.identifier.isi","000305336600027"],["dc.identifier.pmid","22509292"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7572"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8912"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 2.5"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.5"],["dc.title","Natriuretic Peptides for the Detection of Paroxysmal Atrial Fibrillation in Patients with Cerebral Ischemia - the Find-AF Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]