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Gauly, Matthias
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Gauly, Matthias
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Gauly, Matthias
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Gauly, M.
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2014Journal Article [["dc.bibliographiccitation.firstpage","606"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","Veterinary Parasitology"],["dc.bibliographiccitation.lastpage","618"],["dc.bibliographiccitation.volume","205"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Abel, Hansjoerg"],["dc.contributor.author","Savas, Turker"],["dc.contributor.author","Sohnrey, Birgit"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T09:33:37Z"],["dc.date.available","2018-11-07T09:33:37Z"],["dc.date.issued","2014"],["dc.description.abstract","In modern husbandry systems, feed rations for laying hens may contain high levels of dietary fibre, which may only be fermented intestinally. Depending on fermentation properties, the type of dietary fibre may influence the intra-caecal environment constituting the predilection site of Heterakis gallinarum. We investigated egg production dynamics and fecundity of H. gallinarum residing in different caecal environments induced through different types of dietary fibre. Growing layers were fed a standard (CON) or an insoluble(I-) or soluble- (S-) non-starch polysaccharides-(NSP) supplemented diet for the first 11 weeks (wk) of life in a twice-replicated experiment. At 3 wk of age, the birds were infected with 200 embryonated eggs of H. gallinarum. Starting from 3 wk post-infection (p.i.), individual daily total excreta were collected. The number of eggs per gram of faeces (EPG) was determined (N = 2240), and the number of eggs per day (EPD) were estimated. The birds were necropsied 8 wk p.i. and the worm burdens were quantified. The nematode began to lay eggs as early as 23 d.p.i. and thereafter laid on average 436 eggs/d. I-NSP- and S-SNP-supplemented diets expedited the onset of patency by approximately 5 days, and increased total egg excretion by 110% and 185%, respectively, due to higher worm counts. The latter diet (S-SNP) additionally increased total egg excretion by 94% due to enhanced fecundity. Longitudinally collected data showed that fecundity of the nematode (EPD/female) was relatively stable starting from the second week of the patent phase. Results suggest that NSP-induced enlargement of caeca favoured establishment of the nematode while effects of an intensified microbial fermentation through S-NSP were crucial for an enhancement in the worm fecundity. Based on the long-term data obtained from daily collections of total excreta in experimentally H. gallinarum-infected chickens, it is concluded that a diet enriched with pea bran as source of insoluble NSP increased worm egg production merely through elevated worm counts, whereas a diet supplemented with chicory root meal as source of soluble NSP elevated worm egg production through both increased worm counts, and more profoundly through enhanced fecundity. (C) 2014 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.vetpar.2014.08.008"],["dc.identifier.isi","000344425200025"],["dc.identifier.pmid","25200385"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32007"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1873-2550"],["dc.relation.issn","0304-4017"],["dc.title","Egg production dynamics and fecundity of Heterakis gallinarum residing in different caecal environments of chickens induced by fibre-rich diets"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2011Journal Article [["dc.bibliographiccitation.firstpage","182"],["dc.bibliographiccitation.issue","2-3"],["dc.bibliographiccitation.journal","Livestock Science"],["dc.bibliographiccitation.lastpage","187"],["dc.bibliographiccitation.volume","141"],["dc.contributor.author","Kaufmann, Falko"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Sohnrey, Birgit"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T08:50:11Z"],["dc.date.available","2018-11-07T08:50:11Z"],["dc.date.issued","2011"],["dc.description.abstract","This study describes the spectrum and intensity of helminth infections in laying hens kept in organic production systems in Germany. A total of 740 laying hens from 18 organic free range farms were collected between 2007 and 2010. The hens were sacrificed and the gastrointestinal tracts were examined for the presence and intensity of helminth infections with standard parasitological methods. Three nematode (Ascaridia galli, Heterakis gallinarum, Capillaria spp) and four cestode (Raillietina cesticillus, Hymenolepis cantaniana, Hymenolepis carioca, Choanotaenia infundibulum) species were found. Almost all hens (99.6%, N=737) harboured at least one helminth species. Average worm burden per hen was 218.4 (SD=218.3) worms. The most prevalent species were the nematodes Heterakis gallinarum (98%) followed by Ascaridia gall (88%) and Capillaria spp. (75.3%). The overall prevalence of the cestodes was 24.9%. Total worm burden was significantly higher during the summer season when compared with animals slaughtered during winter season (254 vs. 191, P<0.0001). The most dominant helminth species was Heterakis gallinarum averaging 190 (SE = 9.8) worms per hen in the summer and 129 (SE = 8.7) in the winter season (P<0.0001). Average Ascaridia gall burden was 25 (SE = 2.0) in summer and 26 (SE = 1.7) in winter (P=0.1160). Risk of infection with any of the nematodes was 50% higher in summer compared to winter (Psi = 1.49, P<0.0319). Probability of infection with any of the tapeworm species was 3.5 times higher in summer than in winter (P<0.0001). It can be concluded that the vast majority of hens are subclinically infected with at least one helminth species. The prevalence as well as intensity of the helminth infections, particularly with tapeworms, considerably increases in summer. The results indicate that it is essential to adopt alternative control strategies in order to lower infection risk in organic production systems which are gaining popularity. (C) 2011 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.livsci.2011.05.015"],["dc.identifier.isi","000296681000012"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21641"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1871-1413"],["dc.title","Helminth infections in laying hens kept in organic free range systems in Germany"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI WOS2015Journal Article [["dc.bibliographiccitation.firstpage","15"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","British Poultry Science"],["dc.bibliographiccitation.lastpage","21"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Wongrak, Kalyakorn"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","von Borstel, Uta Konig"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T10:02:22Z"],["dc.date.available","2018-11-07T10:02:22Z"],["dc.date.issued","2015"],["dc.description.abstract","Genetic parameters were determined for the worm burden of the most common gastro-intestinal nematodes in two chicken genotypes after being exposed to free-range farming conditions for a laying period. Seventeen-week-old hens of 2 brown genotypes, Lohmann Brown (LB) plus (n=230) and LB classic (n=230), were reared for a laying period and subjected to post-mortem parasitological examinations at 79weeks (LB plus) or 88weeks (LB classic) of age. There was no significant difference in faecal egg counts between the genotypes. Almost all hens (>99%) were infected with at least one nematode species. Species-specific nematode prevalence ranged from 85.8% to 99.1% between the two genotypes. Heterakis gallinarum was the most prevalent nematode (98.5%), followed by Ascaridia galli (96.2%) and Capillaria spp. (86.1%). Capillaria spp. were composed of C. obsignata (79%), C. caudinflata (16%) and C. bursata (5%). All phenotypic and genetic correlations among worm counts of different parasite species were positive in combined genotypes (r(P) ranged from 0.05 to 0.30 and r(G) ranged from 0.29 to 0.88). A strong genetic correlation (r(G)=0.88 +/- 0.34) between counts of A. galli and H. gallinarum was quantified. Heritability for total worm burden for LB plus and LB classic, respectively, were 0.55 +/- 0.18 and 0.55 +/- 0.34. Across both genotypes, the heritability of total worm burden was 0.56 +/- 0.16. In conclusion, there is a high variation attributable to genetic background of chickens in their responses to naturally acquired nematode infections. The high positive genetic correlation between counts of closely related worm species (e.g. A. galli and H. gallinarum) may indicate existence of similar genetically determined mechanism(s) in chickens for controlling these nematodes."],["dc.description.sponsorship","Chandrakasem Rajabhat University, Bangkok, Thailand"],["dc.identifier.doi","10.1080/00071668.2014.981147"],["dc.identifier.isi","000350040700003"],["dc.identifier.pmid","25486507"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38211"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Taylor & Francis Ltd"],["dc.relation.issn","1466-1799"],["dc.relation.issn","0007-1668"],["dc.title","Genetic variation for worm burdens in laying hens naturally infected with gastro-intestinal nematodes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2014Journal Article [["dc.bibliographiccitation.firstpage","139"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Veterinary Parasitology"],["dc.bibliographiccitation.lastpage","146"],["dc.bibliographiccitation.volume","200"],["dc.contributor.author","Tiersch, K. M."],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","von Samson-Himmelstjerna, Georg"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T09:44:20Z"],["dc.date.available","2018-11-07T09:44:20Z"],["dc.date.issued","2014"],["dc.description.abstract","The present study investigated whether incubation media have an impact on infectivity of Capillaria obsignata eggs in chickens infected with gradually increasing doses. C obsignata eggs collected from female worms were incubated either in formalin (0.5% or 2%) or in potassium dichromate 0.1% or in sulfuric acid 0.1 N for three weeks (wk). One-day-old male chicks (N = 92) were reared in a parasite-free environment, and infected with 0, 500, 1000 or 2000 eggs at an age of 3 wk. Post-mortem parasitological examinations were performed on day 28 p.i. Although all the infected birds harboured adult worms, their growth performance was not affected. Furthermore there was no significant interaction effect between incubation media and infection dose on worm establishment rates (P = 0.080), while main effects of these two factors were significant (P < 0.05). The average number of adult worms found in birds infected with the eggs incubated in potassium dichromate were significantly lower (P < 0.001) than in formalin 0.5%, formalin 2% and sulfuric acid 0.1 N. A higher (P < 0.05) percentage of larvae could establish themselves in the intestines when the birds were infected with 500 eggs (40.5%) instead of 2000 eggs (26.2%), indicating density dependent effects. It is concluded that formalin (particularly 0.5%), and sulfuric acid can successfully be used as incubation media for C. obsignata eggs, whereas potassium dichromate impairs subsequent infectivity of the eggs. Although effects of media on the infectivity of the eggs were confirmed to be fairly repeatable, no harmful effect of infection was quantified on the host animal performance with the infection doses up to 2000 eggs. (C) 2013 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.vetpar.2013.11.024"],["dc.identifier.isi","000331507300019"],["dc.identifier.pmid","24365242"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34373"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1873-2550"],["dc.relation.issn","0304-4017"],["dc.title","Artificial infection of chickens with Capillaria obsignata eggs embryonated in different media"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2014Journal Article [["dc.bibliographiccitation.firstpage","314"],["dc.bibliographiccitation.issue","7-8"],["dc.bibliographiccitation.journal","BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT"],["dc.bibliographiccitation.lastpage","321"],["dc.bibliographiccitation.volume","127"],["dc.contributor.author","Wongrak, Kalyakorn"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Moors, Eva"],["dc.contributor.author","Sohnrey, Birgit"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T09:38:00Z"],["dc.date.available","2018-11-07T09:38:00Z"],["dc.date.issued","2014"],["dc.description.abstract","The objective of this study was to monitor establishment and development of gastro-intestinal helminth infections in chickens over two production years (PY) on a free-range farm in Lower Saxony, Germany. The data were collected between July 2010 and June 2011 (PY1) and July 2011 and January 2013 (PY2), respectively. During PY1, Lohmann Brown classic (LB classic, N =450) was tested, while in PY2 two different genotypes (230 LB classic, 230 LB plus) were used. The hens were kept in two mobile stalls that were moved to a new position at regular intervals. In both PY1 and PY2, 20 individual faecal samples per stall were randomly collected at monthly intervals in order to calculate the number of internal parasite eggs per gram of faeces (EPG). At the end of the laying periods, approximately 10% (N = 42) or more than 50% (N = 265) of hens were subjected to post-mortem parasitological examinations in PY1 and PY2, respectively. No parasite eggs were found in the faecal samples during PY1, whereas almost all of the hens (97.6%) were infected with Heterakis gallinarum (36 worms/hen) at the end of the period. In PY2, nematode eggs in faeces were found from the third month onwards at a low level, increasing considerably towards the final three months. There was no significant difference between the two genotypes of brown hens neither for EPG (P = 0.456) or for overall prevalence (P = 0.177). Mortality rate ranged from 18.3 to 27.4% but did not differ significantly between genotypes or production years. Average worm burden was 207 worms/hen in PY2. The most prevalent species were H. gallinarum (98.5%) followed by Ascaridia galli (96.2%) and Capillaria spp. (86.1%). Furthermore, three Capillaria species, C. obsignata, C bursata and C. caudinflata were differentiated. In conclusion chickens kept on free-range farms are exposed to high risks of nematode infections and have high mortality rates with no obvious link to parasite infections. Once the farm environment is contaminated with the nematode eggs, establishment and further spread of nematodes to the hens is a matter of time. This will latest be the case in the second production period, even if the hens are kept in a rotation system and in small herd sizes. This underlines the importance of nematode infections in all free-range systems."],["dc.description.sponsorship","Chandrakasem Rajabhat University, Bangkok, Thailand"],["dc.identifier.doi","10.2376/0005-9366-127-314"],["dc.identifier.isi","000340233600008"],["dc.identifier.pmid","25080825"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32967"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Schluetersche Verlagsgesellschaft Mbh & Co Kg"],["dc.relation.issn","1439-0299"],["dc.relation.issn","0005-9366"],["dc.title","Establishment of gastro-intestinal helminth infections in free-range chickens: a longitudinal on farm study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2011Journal Article [["dc.bibliographiccitation.firstpage","121"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Veterinary Parasitology"],["dc.bibliographiccitation.lastpage","128"],["dc.bibliographiccitation.volume","178"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Abel, Hansjoerg"],["dc.contributor.author","Rautenschlein, Silke"],["dc.contributor.author","Humburg, Julia"],["dc.contributor.author","Schwarz, Anna"],["dc.contributor.author","Breves, Gerhard"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T08:56:00Z"],["dc.date.available","2018-11-07T08:56:00Z"],["dc.date.issued","2011"],["dc.description.abstract","It was hypothesized that the establishment and fecundity of Histomonas meleagridis free Heterakis gallinarum may be affected by dietary non-starch polysaccharides (NSPs). One-day-old female layer chicks (N = 670) were fed ad libitum for 11 wk one of the following diets in a three-times repeated experiment: basal diet (CON), basal diet plus pea bran rich in insoluble NSP (I-NSP), basal diet plus chicory root meal as a source of inulin rich soluble NSP (S-NSP). At the end of wk three, each feeding group was subdivided into an uninfected and an infected group of birds each being inoculated with a placebo or with 200 H. meleagridis free eggs of H. gallinarum. The birds were slaughtered 8 wk post infection and their worm burdens, the nematode egg excretion, caeca sizes and weights as well as intracaecal pH and volatile fatty acid (VFA) concentrations were determined. The NSP supplemented diets and also infection led to reduced body weights (BWs) of birds and impaired the feed conversion rate (P < 0.001). The NSP supplemented diets increased average length of caecum (P < 0.001) with S-NSP exerting a stronger effect than I-NSP (P < 0.05). Full caeca weight was increased by S-NSP (P < 0.001). Feeding S-NSP lowered intracaecal pH and molar proportion of acetate and increased that of butyrate compared to CON and I-NSP (P < 0.001). Caecal pool of VFA was increased with S-NSP (P < 0.001). The NSP-diets elevated incidence of infection (P < 0.01), average number of larvae (P < 0.009) and total worm burden (P < 0.001) compared to CON. The daily amount of faeces increased in NSP-fed birds (P < 0.001). Number of eggs per gram of faeces (EPG), number of eggs excreted per worm population of a bird within 24 h (EPD) and female worm fecundity (EPD/female worm) were elevated after feeding S-NSP (P <= 0.002), whereas I-NSP led to lower EPG/female worm (P < 0.05). The EPD increased in the sequence of CON < I-NSP < S-NSP (P < 0.001). It is concluded that the pea bran and chicory root meal used as sources of insoluble and soluble dietary NSPs, respectively, provided favourable conditions for the establishment of H. gallinarum in grower layers. Chicory root meal additionally enhanced fecundity of the nematode. Therefore, the two natural sources of insoluble and soluble NSPs offer no potential as protecting agents against H. gallinarum infections in chicken. (c) 2010 Elsevier B.V. All rights reserved."],["dc.description.sponsorship","German Research Foundation (DFG); Wilhelm Schaumann Foundation"],["dc.identifier.doi","10.1016/j.vetpar.2010.12.027"],["dc.identifier.isi","000291962200018"],["dc.identifier.pmid","21247704"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23040"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1873-2550"],["dc.relation.issn","0304-4017"],["dc.title","Effects of dietary non-starch polysaccharides on establishment and fecundity of Heterakis gallinarum in grower layers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2014Journal Article [["dc.bibliographiccitation.firstpage","1526"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","animal"],["dc.bibliographiccitation.lastpage","1533"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Wegner, K."],["dc.contributor.author","Lambertz, C."],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Reiner, Johannes R."],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T09:35:48Z"],["dc.date.available","2018-11-07T09:35:48Z"],["dc.date.issued","2014"],["dc.description.abstract","Although the climate in Germany is moderate, heat stress conditions may occur during summer months. However, it is unknown to what extent sow fertility and piglet survival are affected under moderate climatic conditions in indoor systems. Therefore, this study estimated effects of temperature and temperature-humidity index (THI) on sow fertility and piglet survival under practical husbandry conditions. Temperature and relative humidity were recorded in six piglet-producing farms in Lower Saxony, Germany, from July 2011 to August 2012. Based on that, the THI was calculated. In one farrowing, waiting and servicing unit of each farm two data loggers were installed. Reproductive parameters of 8279 successful inseminations and 10 369 litters including total number of piglets born, liveborn, stillborn and weaned piglets as well as pre-weaning mortality were evaluated. The effects of temperature and THI on reproductive parameters were estimated for varying periods after breeding and before and after farrowing, respectively. Average daily temperature across all units ranged from 15.6 degrees C to 29.0 degrees C, and average THI from 62.4 to 75.1. Season and parity significantly affected total number of piglets born, number of liveborn, stillborn and weaned piglets (P < 0.001). The number of piglets born increased with rising temperature and THI in the 1st week post breeding. Higher temperatures and THI values before farrowing resulted in a reduced number of liveborn piglets. Elevated temperature and THI values after farrowing were associated with a greater number of weaned piglets. The pre-weaning mortality significantly decreased with increasing temperature and THI values after farrowing (P < 0.05). In conclusion, temperature and THI affected the reproductive performance of the sows and the survival of the piglets in different ways. While increased climatic values at the time of breeding positively affected the total number of piglets born, increased values at the time of farrowing had negative impacts on the reproductive performance of the sows. Piglets benefited from higher temperature and THI values after farrowing."],["dc.description.sponsorship","Ministry for Education and Research [033L029B]"],["dc.identifier.doi","10.1017/S1751731114001219"],["dc.identifier.isi","000342219000016"],["dc.identifier.pmid","24846319"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12940"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32471"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cambridge Univ Press"],["dc.relation.issn","1751-732X"],["dc.relation.issn","1751-7311"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Climatic effects on sow fertility and piglet survival under influence of a moderate climate"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2011Journal Article [["dc.bibliographiccitation.artnumber","PII 938756233"],["dc.bibliographiccitation.firstpage","277"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Avian Pathology"],["dc.bibliographiccitation.lastpage","287"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Schwarz, Anna"],["dc.contributor.author","Gauly, Matthias"],["dc.contributor.author","Abel, Hansjoerg"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Humburg, Julia"],["dc.contributor.author","Weiss, Alexander"],["dc.contributor.author","Breves, Gerhard"],["dc.contributor.author","Rautenschlein, Silke"],["dc.date.accessioned","2018-11-07T09:00:47Z"],["dc.date.available","2018-11-07T09:00:47Z"],["dc.date.issued","2011"],["dc.description.abstract","Little is known about the induction and modulation of gut-associated immune reactions after nematode infection in the chicken. The objective of the present study was to compare the pathogenesis, induction of immune reactions and electrophysiological changes of the gut after mono-infection with Heterakis gallinarum and after dual infection with H. gallinarum and Histomonas meleagridis in layer chickens. In two experiments 3-week-old chickens were inoculated with embryonated H. gallinarum eggs, which were positive for H. meleagridis. While birds of the first experiment were left untreated, those of the second experiment were treated with dimetridazol to prevent H. meleagridis co-infection. Mild to moderate histological lesions and local immune reactions with a significant increase in CD4+, CD8+, TCR+ and TCR+ cells in the lamina propria and induction of the T-helper type 2 (Th2) cytokine interleukin-13 dominated the H. gallinarum immune response at 2 weeks post infection. Co-infection with H. gallinarum and H. meleagridis induced an increase in mRNA expression of the T-helper type 1 (Th1) cytokine interferon-, a decrease in splenic CD4+ cells and severe destruction of the caecal mucosa in association with strong T-cell infiltration in the caecal lamina propria. There was no obvious effect on the chloride secretion of the caecal epithelium, which was investigated once the mucosa had almost recovered from the infection, in either experiment. These results suggest that the local T-cell reactions to nematode infections in chickens may be comparable with mammals and may be shifted from a Th2-dominated to a Th1-dominated response when accompanied by a protozoan infection."],["dc.identifier.doi","10.1080/03079457.2011.561280"],["dc.identifier.isi","000291806100007"],["dc.identifier.pmid","21711187"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24252"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Taylor & Francis Ltd"],["dc.relation.issn","0307-9457"],["dc.title","Pathobiology of Heterakis gallinarum mono-infection and co-infection with Histomonas meleagridis in layer chickens"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2012Journal Article [["dc.bibliographiccitation.firstpage","110"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Parasitology"],["dc.bibliographiccitation.lastpage","119"],["dc.bibliographiccitation.volume","139"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Abel, Hansjoerg"],["dc.contributor.author","Humburg, Julia"],["dc.contributor.author","Schwarz, A."],["dc.contributor.author","Rautenschlein, Silke"],["dc.contributor.author","Breves, Gerhard"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T09:15:47Z"],["dc.date.available","2018-11-07T09:15:47Z"],["dc.date.issued","2012"],["dc.description.abstract","This study examined whether Ascaridia galli infection can be controlled by dietary non-starch polysaccharides (NSP) in chickens. One-day-old chicks were fed either a basal diet (CON) or CON plus insoluble NSP (I-NSP), or CON plus soluble NSP (S-NSP) for 11 weeks. Three weeks later, birds from half of each feeding group were inoculated with 250 embryonated eggs of A. galli, and slaughtered 8 weeks post-infection to determine worm counts. Both NSP diets, particularly S-NSP, increased prevalence of infection (P<0.05) and worm burden (roughly +50%) of the birds (P<0.001). A. galli infection caused a less efficient (P = 0.013) feed utilization for body weight gain (BWG) resulting in lower body weights (P<0.001) irrespective of type of diet consumed. NSP-fed birds, particularly those on I-NSP, consumed more (+ 8%) feed per unit BWG and showed retarded (P<0.001) BW development compared to CON-fed birds. Intracaecal pH was lowered by S-NSP (P<0.05). Both NSP diets increased the volatile fatty acids pool size in caeca (P<0.001) with S-NSP exerting a greater effect (+ 46%) than I-NSF (+ 24%). It is concluded that both NSPs supplemented diets alter gastrointestinal environment in favour of the nematode establishment, and thus have no potential for controlling A. galli infection in chickens."],["dc.identifier.doi","10.1017/S0031182011001636"],["dc.identifier.isi","000299580900012"],["dc.identifier.pmid","21939584"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8762"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27779"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cambridge Univ Press"],["dc.relation.issn","0031-1820"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","The effects of dietary non-starch polysaccharides on Ascaridia galli infection in grower layers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2014Journal Article [["dc.bibliographiccitation.firstpage","108"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT"],["dc.bibliographiccitation.lastpage","114"],["dc.bibliographiccitation.volume","127"],["dc.contributor.author","Weber, Sabrina"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Waldmann, Karl-Heinz"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T09:43:12Z"],["dc.date.available","2018-11-07T09:43:12Z"],["dc.date.issued","2014"],["dc.description.abstract","Isoflurane-anaesthesia combined with an analgesic represents a welfare-friendly method of pain mitigation for castration of piglets. However, it requires an inhaler device, which is uneconomic for small farms. Sharing a device among farms may be an economical option if the shared use does not increase labour time and the resulting costs. This study aimed to investigate the amount and components of labour time required for piglet castration with isoflurane anaesthesia performed with stationary and shared devices. Piglets (N = 1579) were anaesthetised with isoflurane (using either stationary or shared devices) and castrated. The stationary devices were used in a group (n = 5) of larger farms (84 sows/farm on an average), whereas smaller farms (n = 7; 32 sows/farm on an average) shared one device. Each farm was visited four times and labour time for each process-step was recorded. The complete process included machine set-up, anaesthesia and castration by a practitioner, and preparation, collection and transport of piglets by a farmer. Labour time of the complete process was increased (P = 0.012) on farms sharing a device (266 s/piglet) compared to farms using stationary devices (177 s/piglet), due to increased time for preparation (P = 0.055), castration (P = 0.026) and packing (P = 0.010) when sharing a device. However, components of the time budget of farms using stationary or shared devices did not differ significantly (P>0.05). Cost arising from time spent by farmers did not differ considerably between the use of stationary (0.28(sic) per piglet) and shared (0.26 (sic)) devices. It is concluded that costs arising from the increased labour time due to sharing a device can be considered marginal, since the high expenses originating from purchasing an inhaler device are shared among several farms."],["dc.description.sponsorship","H. Wilhelm Schaumann Stiftung"],["dc.identifier.doi","10.2376/0005-9366-127-108"],["dc.identifier.isi","000332754600003"],["dc.identifier.pmid","24693654"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34123"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Schluetersche Verlagsgesellschaft Mbh & Co Kg"],["dc.relation.issn","1439-0299"],["dc.relation.issn","0005-9366"],["dc.title","Labour time required for piglet castration with isoflurane-anaesthesia using shared and stationary inhaler devices"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS
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