Now showing 1 - 10 of 12
  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","1385"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Cancer Science"],["dc.bibliographiccitation.lastpage","1391"],["dc.bibliographiccitation.volume","111"],["dc.contributor.author","Sharma, Amit"],["dc.contributor.author","Liu, Hongde"],["dc.contributor.author","Tobar‐Tosse, Fabian"],["dc.contributor.author","Noll, Angela"],["dc.contributor.author","Chand Dakal, Tikam"],["dc.contributor.author","Li, Huamei"],["dc.contributor.author","Holz, Frank G."],["dc.contributor.author","Loeffler, Karin U."],["dc.contributor.author","Herwig‐Carl, Martina C."],["dc.date.accessioned","2022-10-06T13:25:01Z"],["dc.date.available","2022-10-06T13:25:01Z"],["dc.date.issued","2020"],["dc.description.sponsorship"," Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659"],["dc.identifier.doi","10.1111/cas.14319"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114731"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1349-7006"],["dc.relation.issn","1347-9032"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.rights.uri","http://creativecommons.org/licenses/by-nc-nd/4.0/"],["dc.title","Genome organization in proximity to the\n BAP1\n locus appears to play a pivotal role in a variety of cancers"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","1071"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Zoological Journal of the Linnean Society"],["dc.bibliographiccitation.lastpage","1073"],["dc.bibliographiccitation.volume","190"],["dc.contributor.author","Dolotovskaya, Sofya"],["dc.contributor.author","Bordallo, Juan Torroba"],["dc.contributor.author","Haus, Tanja"],["dc.contributor.author","Noll, Angela"],["dc.contributor.author","Hofreiter, Michael"],["dc.contributor.author","Zinner, Dietmar"],["dc.contributor.author","Roos, Christian"],["dc.date.accessioned","2022-10-06T13:35:18Z"],["dc.date.available","2022-10-06T13:35:18Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1093/zoolinnean/zlaa026"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116060"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1096-3642"],["dc.relation.issn","0024-4082"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Comparing mitogenomic timetrees for two African savannah primate genera (Chlorocebus and Papio)"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","34"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Immunity, Inflammation and Disease"],["dc.bibliographiccitation.lastpage","46"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Hydes, Theresa"],["dc.contributor.author","Noll, Angela"],["dc.contributor.author","Salinas‐Riester, Gabriela"],["dc.contributor.author","Abuhilal, Mohammed"],["dc.contributor.author","Armstrong, Thomas"],["dc.contributor.author","Hamady, Zaed"],["dc.contributor.author","Primrose, John"],["dc.contributor.author","Takhar, Arjun"],["dc.contributor.author","Walter, Lutz"],["dc.contributor.author","Khakoo, Salim I."],["dc.date.accessioned","2020-12-10T14:06:40Z"],["dc.date.available","2020-12-10T14:06:40Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1002/iid3.190"],["dc.identifier.eissn","2050-4527"],["dc.identifier.issn","2050-4527"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69979"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","IL‐12 and IL‐15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Conference Abstract
    [["dc.bibliographiccitation.journal","Journal of Cerebral Blood Flow & Metabolism"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Bosche, Bert"],["dc.contributor.author","Macdonald, R. Loch"],["dc.contributor.author","Molcanyi, M."],["dc.contributor.author","Rej, Soham"],["dc.contributor.author","Doeppner, Thorsten R."],["dc.contributor.author","Obermann, Mark"],["dc.contributor.author","Mueller, D. J."],["dc.contributor.author","Das, Abhijit"],["dc.contributor.author","Hescheler, Juergen"],["dc.contributor.author","Haertel, F. V."],["dc.contributor.author","Noll, T."],["dc.date.accessioned","2018-11-07T10:25:22Z"],["dc.date.available","2018-11-07T10:25:22Z"],["dc.date.issued","2017"],["dc.format.extent","208"],["dc.identifier.isi","000400157400304"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42848"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Sage Publications Inc"],["dc.publisher.place","Thousand oaks"],["dc.relation.conference","28th International Symposium on Cerebral Blood Flow, Metabolism and Function / 13th International Conference on Quantification of Brain Function with PET"],["dc.relation.eventlocation","Int Soc Cerebral Blood Flow & Metab, Berlin, GERMANY"],["dc.relation.issn","1559-7016"],["dc.relation.issn","0271-678X"],["dc.title","Lithium at low therapeutic concentrations decreases myosin light chain phosphorylation and thereby stabilizes human endothelial barrier"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.artnumber","jeb.235515"],["dc.bibliographiccitation.journal","Journal of Experimental Biology"],["dc.contributor.author","Dong, Yun-wei"],["dc.contributor.author","Blanchard, Tessa S."],["dc.contributor.author","Noll, Angela"],["dc.contributor.author","Vasquez, Picasso"],["dc.contributor.author","Schmitz, Juergen"],["dc.contributor.author","Kelly, Scott P."],["dc.contributor.author","Wright, Patricia A."],["dc.contributor.author","Whitehead, Andrew"],["dc.date.accessioned","2022-10-06T13:26:15Z"],["dc.date.available","2022-10-06T13:26:15Z"],["dc.date.issued","2020"],["dc.description.abstract","The terrestrial radiation of vertebrates required changes in skin that resolved the dual demands of maintaining a mechanical and physiological barrier while also facilitating ion and gas transport. Using the amphibious killifish Kryptolebias marmoratus, we found that transcriptional regulation of skin morphogenesis was quickly activated upon air exposure (1h). Rapid regulation of cell-cell adhesion complexes and pathways that regulate stratum corneum formation was consistent with barrier function and mechanical reinforcement. Unique blood vessel architecture and regulation of angiogenesis likely supported cutaneous respiration. Differences in ionoregulatory transcripts and ionocyte morphology were correlated with differences in salinity acclimation and resilience to air exposure. Evolutionary analyses reinforced the adaptive importance of these mechanisms. We conclude that rapid plasticity of barrier, respiratory, and ionoregulatory functions in skin evolved to support K. marmoratus’ amphibious lifestyle; similar processes may have facilitated the terrestrial radiation of other contemporary and ancient fishes."],["dc.identifier.doi","10.1242/jeb.235515"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115037"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1477-9145"],["dc.relation.issn","0022-0949"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Genomic and physiological mechanisms underlying skin plasticity during water to air transition in an amphibious fish"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","487"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Immunity"],["dc.bibliographiccitation.lastpage","498.e6"],["dc.bibliographiccitation.volume","52"],["dc.contributor.author","Karunakaran, Mohindar M."],["dc.contributor.author","Willcox, Carrie R."],["dc.contributor.author","Salim, Mahboob"],["dc.contributor.author","Paletta, Daniel"],["dc.contributor.author","Fichtner, Alina S."],["dc.contributor.author","Noll, Angela"],["dc.contributor.author","Starick, Lisa"],["dc.contributor.author","Nöhren, Anna"],["dc.contributor.author","Begley, Charlotte R."],["dc.contributor.author","Berwick, Katie A."],["dc.contributor.author","Herrmann, Thomas"],["dc.date.accessioned","2022-10-06T13:33:09Z"],["dc.date.available","2022-10-06T13:33:09Z"],["dc.date.issued","2020"],["dc.description.sponsorship"," http://dx.doi.org/10.13039/100010269 Wellcome Trust"],["dc.description.sponsorship"," http://dx.doi.org/10.13039/501100005972 Deutsche Krebshilfe"],["dc.description.sponsorship"," http://dx.doi.org/10.13039/100008672 Wilhelm–Sanderstiftung"],["dc.description.sponsorship"," http://dx.doi.org/10.13039/501100001659 Deutsche Forschungsgemeinschaft"],["dc.description.sponsorship","SIRIC BRIO"],["dc.description.sponsorship"," Ligue Nationale contre le Cancer http://dx.doi.org/10.13039/501100004099"],["dc.description.sponsorship"," http://dx.doi.org/10.13039/100010269 Wellcome Trust"],["dc.identifier.doi","10.1016/j.immuni.2020.02.014"],["dc.identifier.pii","S1074761320300856"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115557"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","1074-7613"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.artnumber","e12443"],["dc.bibliographiccitation.journal","Genes, brain, and behavior"],["dc.contributor.author","Gutleb, D. R."],["dc.contributor.author","Roos, C."],["dc.contributor.author","Noll, A."],["dc.contributor.author","Ostner, J."],["dc.contributor.author","Schülke, O."],["dc.date.accessioned","2018-02-07T14:52:11Z"],["dc.date.available","2018-02-07T14:52:11Z"],["dc.date.issued","2017"],["dc.description.abstract","The COMT Val158 Met polymorphism is one of the most widely studied genetic polymorphisms in humans implicated in aggression and the moderation of stressful life event effects. We screened a wild primate population for polymorphisms at the COMT Val158 Met site and phenotyped them for aggression to test whether the human polymorphism exists and is associated with variation in aggressive behavior. Subjects were all adults from 4 study groups (37 males, 40 females) of Assamese macaques (Macaca assamensis) in their natural habitat (Phu Khieo Wildlife Sanctuary, Thailand). We collected focal animal behavioral data (27 males, 36 females, 5964 focal hours) and fecal samples for non-invasive DNA analysis. We identified the human COMT Val158 Met polymorphism (14 Met/Met, 41 Val/Met and 22 Val/Val). Preliminary results suggest that COMT genotype and dominance rank interact to influence aggression rates. Aggression rates increased with rank in Val/Val, but decreased in Met/Met and Val/Met individuals, with no significant main effect of COMT genotype on aggression. Further support for the interaction effect comes from time series analyses revealing that when changing from lower to higher rank position Val/Val individuals decreased, whereas Met/Met individuals increased their aggression rate. Contradicting the interpretation of earlier studies, we show that the widely studied Val158 Met polymorphism in COMT is not unique to humans and yields similar behavioral phenotypes in a non-human primate. This study represents an important step towards understanding individual variation in aggression in a wild primate population and may inform human behavioral geneticists about the evolutionary roots of inter-individual variation in aggression."],["dc.identifier.doi","10.1111/gbb.12443"],["dc.identifier.pmid","29194954"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/12034"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1601-183X"],["dc.title","COMT Val158 Met moderates the link between rank and aggression in a non-human primate"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2002Journal Article
    [["dc.bibliographiccitation.artnumber","L69"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The Astrophysical Journal Letters"],["dc.bibliographiccitation.volume","564"],["dc.contributor.author","Ziegler, Bodo L."],["dc.contributor.author","Bohm, A."],["dc.contributor.author","Fricke, K. J."],["dc.contributor.author","Jager, Kitty J."],["dc.contributor.author","Nicklas, H."],["dc.contributor.author","Bender, R."],["dc.contributor.author","Drory, N."],["dc.contributor.author","Gabasch, A."],["dc.contributor.author","Saglia, R. P."],["dc.contributor.author","Seitz, Sebastian"],["dc.contributor.author","Heidt, J."],["dc.contributor.author","Mehlert, D."],["dc.contributor.author","Mollenhoff, C."],["dc.contributor.author","Noll, S."],["dc.contributor.author","Sutorius, E."],["dc.date.accessioned","2018-11-07T10:32:36Z"],["dc.date.available","2018-11-07T10:32:36Z"],["dc.date.issued","2002"],["dc.description.abstract","We present the B-band Tully-Fisher relation (TFR) of 60 late-type galaxies with redshifts 0.1-1. The galaxies were selected from the FORS Deep Field with a limiting magnitude of. Spatially resolved rotation curves R p 23 were derived from spectra obtained with FORS2 at the Very Large Telescope. High-mass galaxies with v(max) greater than or similar to 150 km s(-1) show little evolution, whereas the least massive systems in our sample are brighter by similar to1-2 mag compared with their local counterparts. For the entire distant sample, the TFR slope is flatter than for local field galaxies (-5.77+/-0.45 vs. -7.92+/-0.18). Thus, we find evidence for the evolution of the slope of the TFR with redshift on the 3 sigma level. This is still true when we subdivide the sample into three redshift bins. We speculate that the flatter tilt of our sample is caused by the evolution of luminosities and an additional population of blue galaxies at zgreater than or similar to0.2. The mass dependence of the TFR evolution also leads to variations for different galaxy types in magnitude-limited samples, suggesting that selection effects can account for the discrepant results of previous TFR studies on the luminosity evolution of late-type galaxies."],["dc.identifier.doi","10.1086/338962"],["dc.identifier.isi","000173167300003"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44387"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0004-637X"],["dc.title","The evolution of the Tully-Fisher relation of spiral galaxies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.artnumber","e55232"],["dc.bibliographiccitation.journal","eLife"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Bennstein, Sabrina Bianca"],["dc.contributor.author","Weinhold, Sandra"],["dc.contributor.author","Manser, Angela Riccarda"],["dc.contributor.author","Scherenschlich, Nadine"],["dc.contributor.author","Noll, Angela"],["dc.contributor.author","Raba, Katharina"],["dc.contributor.author","Kögler, Gesine"],["dc.contributor.author","Walter, Lutz"],["dc.contributor.author","Uhrberg, Markus"],["dc.date.accessioned","2022-10-06T13:26:56Z"],["dc.date.available","2022-10-06T13:26:56Z"],["dc.date.issued","2020"],["dc.description.abstract","Despite their identification several years ago, molecular identity and developmental relation between human ILC1 and NK cells, comprising group 1 ILCs, is still elusive. To unravel their connection, thorough transcriptional, epigenetic, and functional characterization was performed from umbilical cord blood (CB). Unexpectedly, ILC1-like cells lacked Tbet expression and failed to produce IFNγ. Moreover, in contrast to previously described ILC1 subsets they could be efficiently differentiated into NK cells. These were characterized by highly diversified KIR repertoires including late stage NKG2A-KIR+ effector cells that are commonly not generated from previously known NK cell progenitor sources. This property was dependent on stroma cell-derived Notch ligands. The frequency of the novel ILC1-like NK cell progenitor (NKP) significantly declined in CB from early to late gestational age. The study supports a model in which circulating fetal ILC1-like NKPs travel to secondary lymphoid tissues to initiate the formation of diversified NK cell repertoires after birth."],["dc.description.sponsorship"," Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659"],["dc.identifier.doi","10.7554/eLife.55232"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115204"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","2050-084X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.rights.uri","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","1508"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Genome Research"],["dc.bibliographiccitation.lastpage","1516"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Churakov, Gennady"],["dc.contributor.author","Zhang, Fengjun"],["dc.contributor.author","Grundmann, Norbert"],["dc.contributor.author","Makalowski, Wojciech"],["dc.contributor.author","Noll, Angela"],["dc.contributor.author","Doronina, Liliya"],["dc.contributor.author","Schmitz, Jürgen"],["dc.date.accessioned","2022-10-06T13:24:56Z"],["dc.date.available","2022-10-06T13:24:56Z"],["dc.date.issued","2020"],["dc.description.abstract","To effectively analyze the increasing amounts of available genomic data, improved comparative analytical tools that are accessible to and applicable by a broad scientific community are essential. We built the “2-n-way” software suite to provide a fundamental and innovative processing framework for revealing and comparing inserted elements among various genomes. The suite comprises two user-friendly web-based modules. The 2-way module generates pairwise whole-genome alignments of target and query species. The resulting genome coordinates of blocks (matching sequences) and gaps (missing sequences) from multiple 2-ways are then transferred to the n-way module and sorted into projects, in which user-defined coordinates from reference species are projected to the block/gap coordinates of orthologous loci in query species to provide comparative information about presence (blocks) or absence (gaps) patterns of targeted elements over many entire genomes and phylogroups. Thus, the 2-n-way software suite is ideal for performing multidirectional, non-ascertainment-biased screenings to extract all possible presence/absence data of user-relevant elements in orthologous sequences. To highlight its applicability and versatility, we used 2-n-way to expose approximately 100 lost introns in vertebrates, analyzed thousands of potential phylogenetically informative bat and whale retrotransposons, and novel human exons as well as thousands of human polymorphic retrotransposons."],["dc.identifier.doi","10.1101/gr.262261.120"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114709"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1549-5469"],["dc.relation.issn","1088-9051"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","The multicomparative 2-n-way genome suite"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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