Kusch, Harald

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[["dc.contributor.author","Bauer, Christian R."],["dc.contributor.author","Knopp, Cornelius"],["dc.contributor.author","Bender, Theresa"],["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Sax, Ulrich"],["dc.creator.author","Ulrich Sax"],["dc.creator.author","Christian R. Bauer"],["dc.creator.author","Theresa Bender"],["dc.creator.author","Harald Kusch"],["dc.creator.author","Cornelius Knopp"],["dc.date.accessioned","2019-10-16T07:41:00Z"],["dc.date.available","2019-10-16T07:41:00Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3205/18gmds093"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62502"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/227"],["dc.language.iso","en"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","63. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)"],["dc.relation.eventlocation","Osnabrück"],["dc.relation.eventstart","2018"],["dc.relation.workinggroup","RG Nußbeck"],["dc.title","Application of basic research data management with FAIRDOM/SEEK from a medical informatics perspective"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","14"],["dc.bibliographiccitation.journal","Environmental and Experimental Botany"],["dc.bibliographiccitation.lastpage","22"],["dc.bibliographiccitation.volume","108"],["dc.contributor.author","Hoppenau, Clara E."],["dc.contributor.author","Tran, Van-Tuan"],["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Aßhauer, Kathrin P."],["dc.contributor.author","Landesfeind, Manuel"],["dc.contributor.author","Meinicke, Peter"],["dc.contributor.author","Popova, Blagovesta"],["dc.contributor.author","Braus-Stromeyer, Susanna A."],["dc.contributor.author","Braus, Gerhard H."],["dc.date.accessioned","2018-04-24T15:04:17Z"],["dc.date.available","2018-04-24T15:04:17Z"],["dc.date.issued","2014"],["dc.description.abstract","The vascular plant pathogen Verticillium dahliae colonizes the xylem fluid where only low nutrient concentrations are provided. Biosynthesis of the vitamin thiamine is connected to oxidative stress. The highly conserved VdThi4 protein is localized in fungal mitochondria and is required under vitamin B1 limiting conditions. Deletion of the corresponding VdTHI4 gene by Agrobacterium-mediated transformation resulted in strains which were impaired in growth on thiamine-free medium and could be rescued by additional vitamin supply or by complementation with the original gene after protoplastation. Furthermore, we show that VdThi4 increases fungal stress tolerance such as UV-damage or oxidative stress. The orthologous sti35 gene of Fusarium oxysporum, another vascular wilt fungus, was shown to be involved in stress response, however to be dispensable for pathogenicity on tomato. In contrast, VdTHI4 is required for fungal-induced tomato disease demonstrated by infection assays with a V. dahliae ΔVdTHI4 deletion strain which is still able to invade plants through the roots but is asymptomatic. Our results suggest remarkable differences between two vascular tomato pathogens where VdThi4 is required for pathogenicity of V. dahliae, whereas F. oxysporum still causes disease when the corresponding Sti35 protein is absent."],["dc.description.sponsorship","Federal Ministry of Education and Research (BMBF)"],["dc.description.sponsorship","Cluster of Excellence and DFG Research Center Nanoscale Microscopy and Molecular Physiology of the Brain"],["dc.identifier.doi","10.1016/j.envexpbot.2013.12.015"],["dc.identifier.other","http://www.sciencedirect.com/science/article/pii/S0098847213002268"],["dc.identifier.pii","S0098847213002268"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/13764"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-575"],["dc.notes.status","zu prüfen"],["dc.relation.issn","0098-8472"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Verticillium dahliae VdTHI4, involved in thiazole biosynthesis, stress response and DNA repair functions, is required for vascular disease induction in tomato"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Adams, Richard"],["dc.contributor.author","Branchett, Susan"],["dc.contributor.author","Dijkman, Ulrike"],["dc.contributor.author","Downie, Alastair"],["dc.contributor.author","Dunning, Alastair"],["dc.contributor.author","Haak, Wouter Hivebench"],["dc.contributor.author","Hanika, Katharina"],["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Maes, Esther"],["dc.contributor.author","Skop, Yannick"],["dc.contributor.author","Stouten, Evelien"],["dc.contributor.author","Studener, Florian"],["dc.contributor.author","Teperek, Marta"],["dc.contributor.author","Therier, Julien"],["dc.date.accessioned","2022-05-16T13:19:53Z"],["dc.date.available","2022-05-16T13:19:53Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.5281/zenodo.1247390"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107981"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/255"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","Digital Notebooks - productivity tools for researchers"],["dc.relation.eventlocation","Delft"],["dc.relation.eventstart","2018-03-15"],["dc.relation.workinggroup","RG Nußbeck"],["dc.title","Digital Notebooks - productivity tools for researchers - event materials"],["dc.type","conference_paper"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Macneil, Rory"],["dc.contributor.orcid","0000-0002-9895-2469"],["dc.creator.author","Harald Kusch"],["dc.creator.author","Rory Macneil"],["dc.date.accessioned","2019-10-16T07:43:19Z"],["dc.date.available","2019-10-16T07:43:19Z"],["dc.date.issued","2018"],["dc.description.abstract","This PDF-file contains the slides presented in Berlin 2016 (ELN Workshop Berlin –14.-15. März 2016)"],["dc.identifier.doi","10.25625/6KXPR8"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62503"],["dc.language.iso","en"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation.conference","ELN Workshop - Max Planck Digital Library"],["dc.relation.date","2016"],["dc.relation.eventlocation","Berlin"],["dc.title","ELNs in the context of Researcher and Lab Workflows and Institutional Infrastructure"],["dc.type","lecture"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Henke, Christian"],["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Marzec, Bartlomiej"],["dc.contributor.author","Nußbeck, Sara Yasemin"],["dc.contributor.author","Umbach, Nadine"],["dc.contributor.orcid","0000-0002-9895-2469"],["dc.creator.author","Kusch, Harald"],["dc.date.accessioned","2019-10-16T07:21:44Z"],["dc.date.available","2019-10-16T07:21:44Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.3205/17gmds094"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62495"],["dc.identifier.url","http://www.egms.de/static/de/meetings/gmds2017/17gmds094.shtml"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/183"],["dc.language.iso","en"],["dc.notes.preprint","yes"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | S02: Hochauflösende Fluoreszenzmikroskopie und integrative Datenanalyse"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)"],["dc.relation.eventlocation","Oldenburg"],["dc.relation.eventstart","2017"],["dc.relation.iserratumof","yes"],["dc.relation.workinggroup","RG Lehnart (Cellular Biophysics and Translational Cardiology Section)"],["dc.relation.workinggroup","RG Nußbeck"],["dc.title","Towards sustainable research data management in advanced light microscopy"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Umbach, Nadine"],["dc.contributor.author","Freckmann, Luca"],["dc.contributor.author","Knopp, Cornelius"],["dc.contributor.author","Meyer, Tim"],["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Kusch, Harald"],["dc.creator.author","Harald Kusch"],["dc.creator.author","Tim Meyer"],["dc.creator.author","Nadine Umbach"],["dc.creator.author","Luca Freckmann"],["dc.creator.author","Cornelius Knopp"],["dc.creator.author","Markus Suhr"],["dc.date.accessioned","2019-10-16T07:34:34Z"],["dc.date.available","2019-10-16T07:34:34Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3205/18gmds098"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62499"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/224"],["dc.language.iso","en"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","63. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)"],["dc.relation.eventend","2018"],["dc.relation.eventlocation","Osnabrück"],["dc.relation.eventstart","2018"],["dc.relation.workinggroup","RG Nußbeck"],["dc.relation.workinggroup","RG Zimmermann (Engineered Human Myocardium)"],["dc.title","From seamless acquisition and sustainable management to publication of next-generation sequencing data"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","291"],["dc.bibliographiccitation.issue","3/4"],["dc.bibliographiccitation.journal","International Journal of Medical Microbiology"],["dc.bibliographiccitation.lastpage","318"],["dc.bibliographiccitation.volume","298"],["dc.contributor.author","Bode, Rüdiger"],["dc.contributor.author","Engelmann, Susanne"],["dc.contributor.author","Hecker, Michael"],["dc.contributor.author","Albrecht, Dirk"],["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Morschhäuser, Joachim"],["dc.creator.author","Hecker M"],["dc.creator.author","Bode R"],["dc.creator.author","Kusch H"],["dc.creator.author","Engelmann S"],["dc.creator.author","Albrecht D"],["dc.creator.author","Morschhäuser J"],["dc.date.accessioned","2019-10-09T09:38:18Z"],["dc.date.available","2019-10-09T09:38:18Z"],["dc.date.issued","2008"],["dc.identifier.doi","10.1016/j.ijmm.2007.03.020"],["dc.identifier.pmid","17588813"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62478"],["dc.language.iso","en"],["dc.title","A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Molecular Plant Pathology"],["dc.contributor.author","Harting, Rebekka"],["dc.contributor.author","Starke, Jessica"],["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Pöggeler, Stefanie"],["dc.contributor.author","Maurus, Isabel"],["dc.contributor.author","Schlüter, Rabea"],["dc.contributor.author","Landesfeind, Manuel"],["dc.contributor.author","Bulla, Ingo"],["dc.contributor.author","Nowrousian, Minou"],["dc.contributor.author","Braus, Gerhard H."],["dc.contributor.author","de Jonge, Ronnie"],["dc.contributor.author","Stahlhut, Gertrud"],["dc.contributor.author","Hoff, Katharina J."],["dc.contributor.author","Aßhauer, Kathrin P."],["dc.contributor.author","Thürmer, Andrea"],["dc.contributor.author","Stanke, Mario"],["dc.contributor.author","Daniel, Rolf"],["dc.contributor.author","Morgenstern, Burkhard"],["dc.contributor.author","Thomma, Bart P. H. J."],["dc.contributor.author","Kronstad, James W."],["dc.contributor.author","Braus‐Stromeyer, Susanna A."],["dc.date.accessioned","2021-06-01T09:42:04Z"],["dc.date.available","2021-06-01T09:42:04Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract Amphidiploid fungal Verticillium longisporum strains Vl43 and Vl32 colonize the plant host Brassica napus but differ in their ability to cause disease symptoms. These strains represent two V. longisporum lineages derived from different hybridization events of haploid parental Verticillium strains. Vl32 and Vl43 carry same‐sex mating‐type genes derived from both parental lineages. Vl32 and Vl43 similarly colonize and penetrate plant roots, but asymptomatic Vl32 proliferation in planta is lower than virulent Vl43. The highly conserved Vl43 and Vl32 genomes include less than 1% unique genes, and the karyotypes of 15 or 16 chromosomes display changed genetic synteny due to substantial genomic reshuffling. A 20 kb Vl43 lineage‐specific (LS) region apparently originating from the Verticillium dahliae‐related ancestor is specific for symptomatic Vl43 and encodes seven genes, including two putative transcription factors. Either partial or complete deletion of this LS region in Vl43 did not reduce virulence but led to induction of even more severe disease symptoms in rapeseed. This suggests that the LS insertion in the genome of symptomatic V. longisporum Vl43 mediates virulence‐reducing functions, limits damage on the host plant, and therefore tames Vl43 from being even more virulent."],["dc.description.abstract","A lineage‐specific region in the Verticillium longisporum Vl43 genome reduces fungal virulence of infected rapeseed host plants. image"],["dc.description.sponsorship","Bundesministerium für Bildung und Forschung: BioFung http://dx.doi.org/10.13039/501100002347"],["dc.description.sponsorship","Natural Sciences and Engineering Research Council of Canada: CREATE http://dx.doi.org/10.13039/501100000038"],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.doi","10.1111/mpp.13071"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85132"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1364-3703"],["dc.relation.issn","1464-6722"],["dc.relation.orgunit","Abteilung Molekulare Mikrobiologie & Genetik"],["dc.rights","CC BY-NC-ND 4.0"],["dc.title","A 20‐kb lineage‐specific genomic region tames virulence in pathogenic amphidiploid Verticillium longisporum"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3518"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","Proteomics"],["dc.bibliographiccitation.lastpage","3530"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Winter, Theresa"],["dc.contributor.author","Winter, Jörn"],["dc.contributor.author","Polak, Martin"],["dc.contributor.author","Kusch, Kathrin"],["dc.contributor.author","Mäder, Ulrike"],["dc.contributor.author","Sietmann, Rabea"],["dc.contributor.author","Ehlbeck, Jörg"],["dc.contributor.author","van Hijum, Sacha"],["dc.contributor.author","Weltmann, Klaus-Dieter"],["dc.contributor.author","Hecker, Michael"],["dc.contributor.author","Kusch, Harald"],["dc.date.accessioned","2019-08-06T11:02:44Z"],["dc.date.available","2019-08-06T11:02:44Z"],["dc.date.issued","2011"],["dc.description.abstract","Plasma medicine and also decontamination of bacteria with physical plasmas is a promising new field of life science with huge interest especially for medical applications. Despite numerous successful applications of low temperature gas plasmas in medicine and decontamination, the fundamental nature of the interactions between plasma and microorganisms is to a large extent unknown. A detailed knowledge of these interactions is essential for the development of new as well as for the enhancement of established plasma-treatment procedures. In the present work we introduce for the first time a growth chamber system suitable for low temperature gas plasma treatment of bacteria in liquid medium. We have coupled the use of this apparatus to a combined proteomic and transcriptomic analyses to investigate the specific stress response of Bacillus subtilis 168 cells to treatment with argon plasma. The treatment with three different discharge voltages revealed not only effects on growth, but also clear evidence of cellular stress responses. B. subtilis suffered severe cell wall stress, which was made visible also by electron microscopy, DNA damages and oxidative stress as a result of exposure to plasma. These biological findings were supported by the detection of reactive plasma species by OES measurements."],["dc.identifier.doi","10.1002/pmic.201000637"],["dc.identifier.pmid","21751354"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62304"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1615-9861"],["dc.relation.issn","1615-9853"],["dc.title","Characterization of the global impact of low temperature gas plasma on vegetative microorganisms"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]