Beerlink, André

[["dc.bibliographiccitation.firstpage","4595"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","Soft Matter"],["dc.bibliographiccitation.lastpage","4601"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Beerlink, André"],["dc.contributor.author","Thutupalli, Shashi"],["dc.contributor.author","Mell, Michael"],["dc.contributor.author","Bartels, Matthias"],["dc.contributor.author","Cloetens, Peter"],["dc.contributor.author","Herminghaus, Stephan"],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:51:49Z"],["dc.date.available","2017-09-07T11:51:49Z"],["dc.date.issued","2012"],["dc.description.abstract","We have used X-ray propagation imaging to visualize a less than 5 nm thick native lipid bilayer membrane freely suspended in aqueous solution. Contrast is formed by free space propagation of hard X-rays, with the membrane illuminated by a nano-focused, partially coherent synchrotron beam, at a controllable distance (defocus) behind the focal spot. Quantitative fitting of the magnified Fresnel fringes shows the transition from membranes swollen with solvent to the native bilayer, containing structural information at near-molecular resolution along the dimension perpendicular to the bilayer. We show first applications of this hybrid technique of propagation imaging and near-field diffraction to the investigation of ultra-thin organic films formed in micro-fluidic devices, namely the formation of a lipid bilayer by the adhesion of two constitutive monolayers."],["dc.identifier.doi","10.1039/c2sm00032f"],["dc.identifier.fs","585071"],["dc.identifier.gro","3146177"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10476"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3931"],["dc.language.iso","en"],["dc.notes","This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively."],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.relation.issn","1744-683X"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.orgunit","Fakultät für Physik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","x-ray imaging"],["dc.subject.gro","membrane biophysics"],["dc.title","X-Ray propagation imaging of a lipid bilayer in solution"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","unknown"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","Physics in Medicine and Biology"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Olendrowitz, Christian"],["dc.contributor.author","Bartels, Matthias"],["dc.contributor.author","Krenkel, Martin"],["dc.contributor.author","Beerlink, André"],["dc.contributor.author","Mokso, R."],["dc.contributor.author","Sprung, Michael"],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:48:27Z"],["dc.date.available","2017-09-07T11:48:27Z"],["dc.date.issued","2012"],["dc.description.abstract","We have analyzed the model organism Caenorhabditis elegans with the help of phase-contrast x-ray tomography. This work combines techniques from x-ray imaging studies of single biological cells by in-line holography with three-dimensional reconstruction and furthermore extends these studies to the multicellular level. To preserve the sub-cellular ultrastructure of the nematodes, we used the near-native sample preparation of high-pressure freezing as commonly used in the field of electron microscopy. For the presented samples, a standard, non-magnifying parallel-beam setting, as well as a magnifying, divergent-beam setting using nanofocusing optics is evaluated based on their tomographic reconstruction potential. In this paper, we address difficulties in sample preparation and issues of image processing. By experimental refinement and through optimized reconstruction procedures, we were able to perform x-ray imaging studies on a living specimen."],["dc.identifier.doi","10.1088/0031-9155/57/16/5309"],["dc.identifier.gro","3142478"],["dc.identifier.isi","000307112600017"],["dc.identifier.pmid","22853964"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8729"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","0031-9155"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","x-ray imaging"],["dc.subject.gro","biomedical tomography"],["dc.title","Phase-contrast x-ray imaging and tomography of the nematode Caenorhabditis elegans"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]