Now showing 1 - 10 of 27
  • 2014Journal Article
    [["dc.bibliographiccitation.artnumber","218"],["dc.bibliographiccitation.journal","SpringerPlus"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Goth, Sabrina"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Buchwald, Christina Unterberg"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Lotz, Joachim"],["dc.date.accessioned","2018-11-07T09:41:07Z"],["dc.date.available","2018-11-07T09:41:07Z"],["dc.date.issued","2014"],["dc.description.abstract","Purpose: Aim of the study was to investigate diagnostic accuracy of cardiac computed tomography angiography (CCTA) between left ventricular end-systolic (LVES) and left ventricular end-diastolic (LVED) cardiac phase for thrombus detection in patient's prior to pulmonary vein isolation (PVI). Materials and methods: 182 consecutive Patients with drug refractory AF scheduled for PVI (62.6% male, mean age 64.1 +/- 10.2 years) underwent routine pre-procedural evaluation including transesophageal echocardiography (TEE) and CCTA for evaluation of left atrial (LA)/left atrial appendage (LAA) anatomy and thrombus formation. Qualitative and quantitative analysis (using aorta ascendens (AA)/LAA ratio) was performed. Measurements of the LA/LAA in LVES and LVED cardiac phase were obtained. Results: End-systolic volumes (LA/LAA) measured in 30 patients without filling defects as control group and all 14 with filling defects of 182 patients were significantly larger (p < 0.01) than in end-diastolic phase. Qualitative analysis was inferior to quantitative analysis using LA/LAA ratio (<0.5; accuracy: 100%, 88%, 100%, 99% vs 100%). 5 out of 182 patients (2.7%) showed thrombus formation of the LAA in CCTA confirmed by TEE and quantitative analysis. Intra/-interobserver variability was lower in end-systolic vs end-diastolic reconstruction interval. Conclusion: For evaluating CCTA datasets in patients prior PVI, the LVES reconstruction interval is recommended due to significantly larger LA/LAA volumes and lower intra/-interobserver variability's."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2014"],["dc.identifier.doi","10.1186/2193-1801-3-218"],["dc.identifier.isi","000359026000005"],["dc.identifier.pmid","25279273"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11751"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33654"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","2193-1801"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Comparison of end-diastolic versus end-systolic cardiac-computed tomography reconstruction interval in patient's prior to pulmonary vein isolation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article Research Paper
    [["dc.bibliographiccitation.artnumber","e109164"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Lamata, Pablo"],["dc.contributor.author","Hussain, Shazia T."],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Bigalke, Boris"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2017-09-07T11:45:27Z"],["dc.date.available","2017-09-07T11:45:27Z"],["dc.date.issued","2014"],["dc.description.abstract","Objectives: Cardiovascular magnetic resonance feature tracking (CMR-FT) offers quantification of myocardial deformation from routine cine images. However, data using CMR-FT to quantify left ventricular (LV) torsion and diastolic recoil are not yet available. We therefore sought to evaluate the feasibility and reproducibility of CMR-FT to quantify LV torsion and peak recoil rate using an optimal anatomical approach. Methods: Short-axis cine stacks were acquired at rest and during dobutamine stimulation (10 and 20 mu g.kg(-1).min(-1)) in 10 healthy volunteers. Rotational displacement was analysed for all slices. A complete 3D-LV rotational model was developed using linear interpolation between adjacent slices. Torsion was defined as the difference between apical and basal rotation, divided by slice distance. Depending on the distance between the most apical (defined as 0% LV distance) and basal (defined as 100% LV distance) slices, four different models for the calculation of torsion were examined: Model-1 (25-75%), Model-2 (0-100%), Model-3 (25-100%) and Model-4 (0-75%). Analysis included subendocardial, subepicardial and global torsion and recoil rate (mean of subendocardial and subepicardial values). Results: Quantification of torsion and recoil rate was feasible in all subjects. There was no significant difference between the different models at rest. However, only Model-1 (25-75%) discriminated between rest and stress (Global Torsion: 2.7 +/- 1.5 degrees cm(-1), 3.6 +/- 2.0 degrees cm(-1), 5.1 +/- 2.2 degrees cm(-1), p<0.01; Global Recoil Rate: -30.1 +/- 11.1 degrees cm(-1) s (-1), -469 +/- 15.0 degrees cm (-1) s (-1), -68.9 +/- 32.3 degrees cm(-1) s(-1), p<0.01; for rest, 10 and 20 mu g.kg(-1).min(-1) of dobutamine, respectively). Reproducibility was sufficient for all parameters as determined by Bland-Altman analysis, intraclass correlation coefficients and coefficient of variation. Conclusions: CMR-FT based derivation of myocardial torsion and recoil rate is feasible and reproducible at rest and with dobutamine stress. Using an optimal anatomical approach measuring rotation at 25% and 75% apical and basal LV locations allows effective quantification of torsion and recoil dynamics. Application of these new measures of deformation by CMR-FT should next be explored in disease states."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2014"],["dc.identifier.doi","10.1371/journal.pone.0109164"],["dc.identifier.gro","3142035"],["dc.identifier.isi","000345743700050"],["dc.identifier.pmid","25285656"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3823"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Quantification of Left Ventricular Torsion and Diastolic Recoil Using Cardiovascular Magnetic Resonance Myocardial Feature Tracking"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","e0202146"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Stiermaier, Thomas"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Chiribiri, Amedeo"],["dc.contributor.author","Möller, Christian"],["dc.contributor.author","Graf, Tobias"],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Villa, Adriana"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Thiele, Holger"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Eitel, Ingo"],["dc.contributor.editor","Novo, Giuseppina"],["dc.date.accessioned","2020-12-10T18:42:08Z"],["dc.date.available","2020-12-10T18:42:08Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1371/journal.pone.0202146"],["dc.identifier.eissn","1932-6203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15691"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77819"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Right ventricular strain assessment by cardiovascular magnetic resonance myocardial feature tracking allows optimized risk stratification in Takotsubo syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.artnumber","601"],["dc.bibliographiccitation.journal","SpringerPlus"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Ritter, Christian"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.date.accessioned","2018-11-07T09:33:32Z"],["dc.date.available","2018-11-07T09:33:32Z"],["dc.date.issued","2014"],["dc.description.abstract","Introduction: Situs inversus totalis with congenitally corrected transposition of the great arteries represents a relatively rare congenital condition. Case description: The current report describes the case of a 56 year old patient with an atrio-ventricular and ventricular-arterial discordance of the heart chambers without surgical correction, incidentally detected during hepatocellular carcinoma evaluation. The systemic venous blood arrived via the right atrium and a mitral valve in the morphologically left but pulmonary arterial ventricle that gave rise to a pulmonary trunk. The pulmonary venous blood passed the left atrium and the tricuspid valve into a morphologically right but systemic ventricle that gave rise to the aorta. Discussion and evaluation: The switched anatomy was incidentally detected on echocardiography. The patient was referred to cardiac magnetic resonance imaging (CMR) including flow measurements, volumetry and late enhancement. CMR results showed a mildly impaired function and the switched anatomy. During a follow-up period of 2 years the patient was suffering from only mild heart failure and dyspnea. Conclusions: Heart failure symptoms and arrhythmias can appear with increasing age in patients with congenitally corrected transposition. Early CMR allows accurate diagnosis and timely introduction of adequate therapy thereby avoiding disease progression."],["dc.identifier.doi","10.1186/2193-1801-3-601"],["dc.identifier.isi","000359108200001"],["dc.identifier.pmid","25392774"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11150"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31986"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","2193-1801"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Situs inversus totalis with congenitally corrected transposition of the great arteries: insights from cardiac MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.artnumber","965512"],["dc.bibliographiccitation.journal","Frontiers in Cardiovascular Medicine"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Evertz, Ruben"],["dc.contributor.author","Schulz, Alexander"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Backhaus, Sören J."],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","von Haehling, Stephan"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2022-10-04T10:21:43Z"],["dc.date.available","2022-10-04T10:21:43Z"],["dc.date.issued","2022"],["dc.description.abstract","Background\r\n The risk of myocarditis after mRNA vaccination against COVID-19 has emerged recently. Current evidence suggests that young male patients are predominantly affected. In the majority of the cases, only mild symptoms were observed. However, little is known about cardiac magnetic resonance (CMR) imaging patterns in mRNA-related myocarditis and their differences when compared to classical viral myocarditis in the acute phase of inflammation.\r\n \r\n \r\n Methods and results\r\n \r\n In total, 10 mRNA vaccination-associated patients with myocarditis were retrospectively enrolled in this study and compared to 10 patients suffering from viral myocarditis, who were matched for age, sex, comorbidities, and laboratory markers. All patients (\r\n n\r\n = 20) were hospitalized and underwent a standardized clinical examination, as well as an echocardiography and a CMR. Both, clinical and imaging findings and, in particular, functional and volumetric CMR assessments, as well as detailed tissue characterization using late gadolinium enhancement and T1 + T2-weighted sequences, were compared between both groups. The median age of the overall cohort was 26 years (group 1: 25.5; group 2: 27.5;\r\n p\r\n = 0.57). All patients described chest pain as the leading reason for their initial presentation. CMR volumetric and functional parameters did not differ significantly between both groups. In all cases, the lateral left ventricular wall showed late gadolinium enhancement without significant differences in terms of the localization or in-depth tissue characterization (late gadolinium enhancement [LGE] enlargement: group 1: 5.4%; group 2: 6.5%;\r\n p\r\n = 0.14; T2 global/maximum value: group 1: 38.9/52 ms; group 2: 37.8/54.5 ms;\r\n p\r\n = 0.79 and\r\n p\r\n = 0.80).\r\n \r\n \r\n \r\n Conclusion\r\n This study yielded the first evidence that COVID-19 mRNA vaccine-associated myocarditis does not show specific CMR patterns during the very acute stage in the most affected patient group of young male patients. The observed imaging markers were closely related to regular viral myocarditis in our cohort. Additionally, we could not find any markers implying adverse outcomes in this relatively little number of patients; however, this has to be confirmed by future studies that will include larger sample sizes."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3389/fcvm.2022.965512"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114481"],["dc.notes.intern","DOI-Import GROB-600"],["dc.relation.eissn","2297-055X"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Cardiovascular magnetic resonance imaging patterns of acute COVID-19 mRNA vaccine-associated myocarditis in young male patients: A first single-center experience"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article
    [["dc.bibliographiccitation.firstpage","3970"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","Journal of Clinical Medicine"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Evertz, Ruben"],["dc.contributor.author","Hub, Sebastian"],["dc.contributor.author","Backhaus, Sören J."],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Toischer, Karl"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.editor","Santarpino, Giuseppe"],["dc.date.accessioned","2021-10-01T09:58:14Z"],["dc.date.available","2021-10-01T09:58:14Z"],["dc.date.issued","2021"],["dc.description.abstract","Aortic valve calcification (AVC) in aortic stenosis patients has diagnostic and prognostic implications. Little is known about the interchangeability of AVC obtained from different multidetector computed tomography (MDCT) software solutions. Contrast-enhanced MDCT data sets of 50 randomly selected aortic stenosis patients were analysed using three different software vendors (3Mensio, CVI42, Syngo.Via). A subset of 10 patients were analysed twice for the estimation of intra-observer variability. Intra- and inter-observer variability were determined using the ICC reliability method, Bland-Altman analysis and coefficients of variation. No differences were revealed between the software solutions in the AVC calculations (3Mensio 941 ± 623, Syngo.Via 948 mm3 ± 655, CVI42 941 ± 637; p = 0.455). The best inter-vendor agreement was found between the CVI42 and the Syngo.Via (ICC 0.997 (CI 0.995–0.998)), followed by the 3Mensio and the CVI42 (ICC 0.996 (CI 0.922–0.998)), and the 3Mensio and the Syngo.Via (ICC 0.992 (CI 0.986–0.995)). There was excellent intra- (3Mensio: ICC 0.999 (0.995–1.000); CVI42: ICC 1.000 (0.999–1.000); Syngo.Via: ICC 0.998 (0.993–1.000)) and inter-observer variability (3Mensio: ICC 1.000 (0.999–1.000); CVI42: ICC 1.000 (1.000–1.000); Syngo.Via: ICC 0.996 (0.985–0.999)) for all software types. Contrast-enhanced MDCT-derived AVC scores are interchangeable between and reproducible within different commercially available software solutions. This is important since sufficient reproducibility, interchangeability and valid results represent prerequisites for accurate TAVR planning and its widespread clinical use."],["dc.description.abstract","Aortic valve calcification (AVC) in aortic stenosis patients has diagnostic and prognostic implications. Little is known about the interchangeability of AVC obtained from different multidetector computed tomography (MDCT) software solutions. Contrast-enhanced MDCT data sets of 50 randomly selected aortic stenosis patients were analysed using three different software vendors (3Mensio, CVI42, Syngo.Via). A subset of 10 patients were analysed twice for the estimation of intra-observer variability. Intra- and inter-observer variability were determined using the ICC reliability method, Bland-Altman analysis and coefficients of variation. No differences were revealed between the software solutions in the AVC calculations (3Mensio 941 ± 623, Syngo.Via 948 mm3 ± 655, CVI42 941 ± 637; p = 0.455). The best inter-vendor agreement was found between the CVI42 and the Syngo.Via (ICC 0.997 (CI 0.995–0.998)), followed by the 3Mensio and the CVI42 (ICC 0.996 (CI 0.922–0.998)), and the 3Mensio and the Syngo.Via (ICC 0.992 (CI 0.986–0.995)). There was excellent intra- (3Mensio: ICC 0.999 (0.995–1.000); CVI42: ICC 1.000 (0.999–1.000); Syngo.Via: ICC 0.998 (0.993–1.000)) and inter-observer variability (3Mensio: ICC 1.000 (0.999–1.000); CVI42: ICC 1.000 (1.000–1.000); Syngo.Via: ICC 0.996 (0.985–0.999)) for all software types. Contrast-enhanced MDCT-derived AVC scores are interchangeable between and reproducible within different commercially available software solutions. This is important since sufficient reproducibility, interchangeability and valid results represent prerequisites for accurate TAVR planning and its widespread clinical use."],["dc.identifier.doi","10.3390/jcm10173970"],["dc.identifier.pii","jcm10173970"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/90018"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-469"],["dc.publisher","MDPI"],["dc.relation.eissn","2077-0383"],["dc.rights","Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."],["dc.title","Head-to-Head Comparison of Different Software Solutions for AVC Quantification Using Contrast-Enhanced MDCT"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2021-05-17Journal Article Research Paper
    [["dc.bibliographiccitation.artnumber","60"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Magnetic Resonance"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Metschies, Georg"],["dc.contributor.author","Billing, Marcus"],["dc.contributor.author","Schmidt-Rimpler, Jonas"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Gertz, Roman J."],["dc.contributor.author","Lapinskas, Tomas"],["dc.contributor.author","Pieske-Kraigher, Elisabeth"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Bigalke, Boris"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Kelle, Sebastian"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Backhaus, Sören J."],["dc.date.accessioned","2021-11-25T11:12:48Z"],["dc.date.available","2021-11-25T11:12:48Z"],["dc.date.issued","2021-05-17"],["dc.date.updated","2021-11-19T12:47:36Z"],["dc.description.abstract","Abstract Background Myocardial deformation analyses using cardiovascular magnetic resonance (CMR) feature tracking (CMR-FT) have incremental value in the assessment of cardiac function beyond volumetric analyses. Since guidelines do not recommend specific imaging parameters, we aimed to define optimal spatial and temporal resolutions for CMR cine images to enable reliable post-processing. Methods Intra- and inter-observer reproducibility was assessed in 12 healthy subjects and 9 heart failure (HF) patients. Cine images were acquired with different temporal (20, 30, 40 and 50 frames/cardiac cycle) and spatial resolutions (high in-plane 1.5 × 1.5 mm through-plane 5 mm, standard 1.8 × 1.8 x 8mm and low 3.0 × 3.0 x 10mm). CMR-FT comprised left ventricular (LV) global and segmental longitudinal/circumferential strain (GLS/GCS) and associated systolic strain rates (SR), and right ventricular (RV) GLS. Results Temporal but not spatial resolution did impact absolute strain and SR. Maximum absolute changes between lowest and highest temporal resolution were as follows: 1.8% and 0.3%/s for LV GLS and SR, 2.5% and 0.6%/s for GCS and SR as well as 1.4% for RV GLS. Changes of strain values occurred comparing 20 and 30 frames/cardiac cycle including LV and RV GLS and GCS (p < 0.001–0.046). In contrast, SR values (LV GLS/GCS SR) changed significantly comparing all successive temporal resolutions (p < 0.001–0.013). LV strain and SR reproducibility was not affected by either temporal or spatial resolution, whilst RV strain variability decreased with augmentation of temporal resolution. Conclusion Temporal but not spatial resolution significantly affects strain and SR in CMR-FT deformation analyses. Strain analyses require lower temporal resolution and 30 frames/cardiac cycle offer consistent strain assessments, whilst SR measurements gain from further increases in temporal resolution."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.citation","Journal of Cardiovascular Magnetic Resonance. 2021 May 17;23(1):60"],["dc.identifier.doi","10.1186/s12968-021-00740-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/93537"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.publisher","BioMed Central"],["dc.relation.eissn","1532-429X"],["dc.relation.orgunit","Klinik für Kardiologie und Pneumologie"],["dc.rights","CC BY 4.0"],["dc.rights.holder","The Author(s)"],["dc.subject","Myocardial deformation"],["dc.subject","Strain"],["dc.subject","Cardiovascular magnetic resonance"],["dc.subject","Temporal resolution"],["dc.subject","Spatial resolution"],["dc.subject","Reproducibility"],["dc.title","Defining the optimal temporal and spatial resolution for cardiovascular magnetic resonance imaging feature tracking"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article Research Paper
    [["dc.bibliographiccitation.artnumber","11648"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Backhaus, Sören J."],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Stehning, Christian"],["dc.contributor.author","Billing, Marcus"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Kelle, Sebastian"],["dc.contributor.author","Kowallick, Johannes T."],["dc.date.accessioned","2021-07-05T15:00:34Z"],["dc.date.available","2021-07-05T15:00:34Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract Cardiovascular magnetic resonance (CMR) imaging provides reliable assessments of biventricular morphology and function. Since manual post-processing is time-consuming and prone to observer variability, efforts have been directed towards novel artificial intelligence-based fully automated analyses. Hence, we sought to investigate the impact of artificial intelligence-based fully automated assessments on the inter-study variability of biventricular volumes and function. Eighteen participants (11 with normal, 3 with heart failure and preserved and 4 with reduced ejection fraction (EF)) underwent serial CMR imaging at in median 63 days (range 49–87) interval. Short axis cine stacks were acquired for the evaluation of left ventricular (LV) mass, LV and right ventricular (RV) end-diastolic, end-systolic and stroke volumes as well as EF. Assessments were performed manually (QMass, Medis Medical Imaging Systems, Leiden, Netherlands) by an experienced (3 years) and inexperienced reader (no active reporting, 45 min of training with five cases from the SCMR consensus data) as well as fully automated (suiteHEART, Neosoft, Pewaukee, WI, USA) without any manual corrections. Inter-study reproducibility was overall excellent with respect to LV volumetric indices, best for the experienced observer (intraclass correlation coefficient (ICC) > 0.98, coefficient of variation (CoV, < 9.6%) closely followed by automated analyses (ICC > 0.93, CoV < 12.4%) and lowest for the inexperienced observer (ICC > 0.86, CoV < 18.8%). Inter-study reproducibility of RV volumes was excellent for the experienced observer (ICC > 0.88, CoV < 10.7%) but considerably lower for automated and inexperienced manual analyses (ICC > 0.69 and > 0.46, CoV < 22.8% and < 28.7% respectively). In this cohort, fully automated analyses allowed reliable serial investigations of LV volumes with comparable inter-study reproducibility to manual analyses performed by an experienced CMR observer. In contrast, RV automated quantification with current algorithms still relied on manual post-processing for reliability."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.doi","10.1038/s41598-021-90702-9"],["dc.identifier.pii","90702"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/87853"],["dc.language.iso","en"],["dc.notes.intern","DOI Import DOI-Import GROB-441"],["dc.relation.eissn","2045-2322"],["dc.rights","CC BY 4.0"],["dc.title","Impact of fully automated assessment on interstudy reproducibility of biventricular volumes and function in cardiac magnetic resonance imaging"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article Research Paper
    [["dc.bibliographiccitation.artnumber","36"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Magnetic Resonance"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Morton, Geraint"],["dc.contributor.author","Lamata, Pablo"],["dc.contributor.author","Jogiya, Roy"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Nagel, Eike"],["dc.contributor.author","Chiribiri, Amedeo"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2017-09-07T11:44:24Z"],["dc.date.available","2017-09-07T11:44:24Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Cardiovascular magnetic resonance (CMR) offers quantification of phasic atrial functions based on volumetric assessment and more recently, on CMR feature tracking (CMR-FT) quantitative strain and strain rate (SR) deformation imaging. Inter-study reproducibility is a key requirement for longitudinal studies but has not been defined for CMR-based quantification of left atrial (LA) and right atrial (RA) dynamics. Methods: Long-axis 2-and 4-chamber cine images were acquired at 9: 00 (Exam A), 9: 30 (Exam B) and 14: 00 (Exam C) in 16 healthy volunteers. LA and RA reservoir, conduit and contractile booster pump functions were quantified by volumetric indexes as derived from fractional volume changes and by strain and SR as derived from CMR-FT. Exam A and B were compared to assess the inter-study reproducibility. Morning and afternoon scans were compared to address possible diurnal variation of atrial function. Results: Inter-study reproducibility was within acceptable limits for all LA and RA volumetric, strain and SR parameters. Inter-study reproducibility was better for volumetric indexes and strain than for SR parameters and better for LA than for RA dynamics. For the LA, reservoir function showed the best reproducibility (intraclass correlation coefficient (ICC) 0.94-0.97, coefficient of variation (CoV) 4.5-8.2 %), followed by conduit (ICC 0.78-0.97, CoV 8.2-18.5 %) and booster pump function (ICC 0.71-0.95, CoV 18.3-22.7). Similarly, for the RA, reproducibility was best for reservoir function (ICC 0.76-0.96, CoV 7.5-24.0 %) followed by conduit (ICC 0.67-0.91, CoV 13.9-35.9) and booster pump function (ICC 0.73-0.90, CoV 19.4-32.3). Atrial dynamics were not measurably affected by diurnal variation between morning and afternoon scans. Conclusions: Inter-study reproducibility for CMR-based derivation of LA and RA functions is acceptable using either volumetric, strain or SR parameters with LA function showing higher reproducibility than RA function assessment. Amongst the different functional components, reservoir function is most reproducibly assessed by either technique followed by conduit and booster pump function, which needs to be considered in future longitudinal research studies."],["dc.identifier.doi","10.1186/s12968-015-0140-2"],["dc.identifier.gro","3141902"],["dc.identifier.isi","000354940100001"],["dc.identifier.pmid","25982348"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12359"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/2345"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Biomed Central Ltd"],["dc.relation.eissn","1532-429X"],["dc.relation.issn","1097-6647"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Quantification of atrial dynamics using cardiovascular magnetic resonance: inter-study reproducibility"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","505"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","508"],["dc.bibliographiccitation.volume","18"],["dc.contributor.affiliation","Brunnert, Fiona; 1\r\nDepartment of Dermatology\r\nVenereology and Allergology\r\nUniversity Medical Center\r\nGöttingen Germany"],["dc.contributor.affiliation","Erpenbeck, Luise; 1\r\nDepartment of Dermatology\r\nVenereology and Allergology\r\nUniversity Medical Center\r\nGöttingen Germany"],["dc.contributor.affiliation","Vlahova, Lyubomira; 1\r\nDepartment of Dermatology\r\nVenereology and Allergology\r\nUniversity Medical Center\r\nGöttingen Germany"],["dc.contributor.affiliation","Kowallick, Johannes T.; 2\r\nInstitute for Diagnostic and Interventional Radiology\r\nUniversity Medical Center\r\nGöttingen Germany"],["dc.contributor.affiliation","Thoms, Kai‐Martin; 1\r\nDepartment of Dermatology\r\nVenereology and Allergology\r\nUniversity Medical Center\r\nGöttingen Germany"],["dc.contributor.affiliation","Schön, Michael P.; 1\r\nDepartment of Dermatology\r\nVenereology and Allergology\r\nUniversity Medical Center\r\nGöttingen Germany"],["dc.contributor.author","Brunnert, Fiona"],["dc.contributor.author","Erpenbeck, Luise"],["dc.contributor.author","Vlahova, Lyubomira"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Thoms, Kai‐Martin"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Mitteldorf, Christina"],["dc.date.accessioned","2021-04-14T08:26:37Z"],["dc.date.available","2021-04-14T08:26:37Z"],["dc.date.issued","2020"],["dc.date.updated","2022-11-11T13:13:44Z"],["dc.identifier.doi","10.1111/ddg.14082"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82016"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.rights","This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made."],["dc.title","Painful induration of the thigh"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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