Kunze-Szikszay, Nils

[["dc.bibliographiccitation.artnumber","46"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","MS, Roessler"],["dc.contributor.author","Riffelmann, M"],["dc.contributor.author","Kunze-Szikszay, N."],["dc.contributor.author","Lier, M"],["dc.contributor.author","Schmid, O"],["dc.contributor.author","Haus, H"],["dc.contributor.author","Schneider, S"],["dc.contributor.author","JF, Heuer"],["dc.date.accessioned","2021-04-14T08:28:07Z"],["dc.date.accessioned","2022-08-16T12:42:16Z"],["dc.date.available","2021-04-14T08:28:07Z"],["dc.date.available","2022-08-16T12:42:16Z"],["dc.date.issued","2021-03-11"],["dc.date.updated","2022-07-29T12:17:56Z"],["dc.description.abstract","Abstract\r\n \r\n Background\r\n Spinal stabilisation is recommended for prehospital trauma treatment. In Germany, vacuum mattresses are traditionally used for spinal stabilisation, whereas in anglo-american countries, long spine boards are preferred. While it is recommended that the on-scene time is as short as possible, even less than 10 minutes for unstable patients, spinal stabilisation is a time-consuming procedure. For this reason, the time needed for spinal stabilisation may prevent the on-scene time from being brief. The aim of this simulation study was to compare the time required for spinal stabilisation between a scoop stretcher in conjunction with a vacuum mattress and a long spine board.\r\n \r\n \r\n Methods\r\n Medical personnel of different professions were asked to perform spinal immobilizations with both methods. A total of 172 volunteers were immobilized under ideal conditions as well as under realistic conditions. A vacuum mattress was used for 78 spinal stabilisations, and a long spinal board was used for 94. The duration of the procedures were measured by video analysis.\r\n \r\n \r\n Results\r\n Under ideal conditions, spinal stabilisation on a vacuum mattress and a spine board required 254.4 s (95 % CI 235.6–273.2 s) and 83.4 s (95 % CI 77.5–89.3 s), respectively (p < 0.01). Under realistic conditions, the vacuum mattress and spine board required 358.3 s (95 % CI 316.0–400.6 s) and 112.6 s (95 % CI 102.6–122.6 s), respectively (p < 0.01).\r\n \r\n \r\n Conclusions\r\n Spinal stabilisation for trauma patients is significantly more time consuming on a vacuum mattress than on a long spine board. Considering that the prehospital time of EMS should not exceed 60 minutes and the on-scene time should not exceed 30 minutes or even 10 minutes if the patient is in extremis, based on our results, spinal stabilisation on a vacuum mattress may consume more than 20 % of the recommended on-scene time. In contrast, stabilisation on a spine board requires only one third of the time required for that on a vacuum mattress.\r\n We conclude that a long spine board may be feasible for spinal stabilisation for critical trauma patients with timesensitive life threatening ABCDE-problems to ensure the shortest possible on-scene time for prehospital trauma treatment, not least if a patient has to be rescued from an open or inaccessible terrain, especially that with uneven overgrown land."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.citation","Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 2021 Mar 11;29(1):46"],["dc.identifier.doi","10.1186/s13049-021-00854-w"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17743"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82507"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112740"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1757-7241"],["dc.relation.orgunit","Klinik für Anästhesiologie"],["dc.rights","CC BY 4.0"],["dc.rights.holder","The Author(s)"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject","Long spine board"],["dc.subject","Prehospital trauma treatment"],["dc.subject","Spinal stabilisation"],["dc.subject","Vacuum mattress"],["dc.title","Vacuum mattress or long spine board: which method of spinal stabilisation in trauma patients is more time consuming? A simulation study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","122"],["dc.bibliographiccitation.journal","Scandinavian Journal of Trauma Resuscitation and Emergency Medicine"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Kunze-Szikszay, Nils"],["dc.contributor.author","Krack, Lennart A."],["dc.contributor.author","Wildenauer, Pauline"],["dc.contributor.author","Wand, Saskia"],["dc.contributor.author","Heyne, Tim"],["dc.contributor.author","Walliser, Karoline"],["dc.contributor.author","Spering, Christopher"],["dc.contributor.author","Bauer, Martin"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Roessler, Markus"],["dc.date.accessioned","2018-11-07T10:07:07Z"],["dc.date.available","2018-11-07T10:07:07Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: Hyperfibrinolysis (HF) is a major contributor to coagulopathy and mortality in trauma patients. This study investigated (i) the rate of HF during the pre-hospital management of patients with multiple injuries and (ii) the effects of pre-hospital tranexamic acid (TxA) administration on the coagulation system. Methods: From 27 trauma patients with pre-hospital an estimated injury severity score (ISS) >= 16 points blood was obtained at the scene and on admission to the emergency department (ED). All patients received 1 g of TxA after the first blood sample was taken. Rotational thrombelastometry (ROTEM) was performed for both blood samples, and the results were compared. HF was defined as a maximum lysis (ML) >15 % in EXTEM. Results: The median (min-max) ISS was 17 points (4-50 points). Four patients (15 %) had HF diagnosed via ROTEM at the scene, and 2 patients (7.5 %) had HF diagnosed via ROTEM on admission to the ED. The median ML before TxA administration was 11 % (3-99 %) vs. 10 % after TxA administration (4-18 %; p > 0.05). TxA was administered 37 min (10-85 min) before ED arrival. The ROTEM results before and after TxA administration did not significantly differ. No adverse drug reactions were observed after TxA administration. Discussion: HF can be present in severely injured patients during pre-hospital care. Antifibrinolytic therapy administered at the scene is a significant time saver. Even in milder trauma fibrinogen can be decreased to critically low levels. Early administration of TxA cannot reverse or entirely stop this decrease. Conclusions: The pre-hospital use of TxA should be considered for severely injured patients to prevent the worsening of trauma-induced coagulopathy and unnecessarily high fibrinogen consumption."],["dc.identifier.doi","10.1186/s13049-016-0314-4"],["dc.identifier.isi","000384950400003"],["dc.identifier.pmid","27724970"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13894"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39223"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1757-7241"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","The pre-hospital administration of tranexamic acid to patients with multiple injuries and its effects on rotational thrombelastometry: a prospective observational study in pre-hospital emergency medicine"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","69"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Microbiology"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Kunze-Szikszay, Nils"],["dc.contributor.author","Euler, Maximilian"],["dc.contributor.author","Kuhns, Martin"],["dc.contributor.author","Thieß, Melanie"],["dc.contributor.author","Groß, Uwe"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Perl, Thorsten"],["dc.date.accessioned","2021-04-14T08:28:09Z"],["dc.date.accessioned","2022-08-18T12:35:52Z"],["dc.date.available","2021-04-14T08:28:09Z"],["dc.date.available","2022-08-18T12:35:52Z"],["dc.date.issued","2021-02-28"],["dc.date.updated","2022-07-29T12:07:23Z"],["dc.description.abstract","Abstract\r\n \r\n Background\r\n Hospital-acquired pneumonia (HAP) is a common problem in intensive care medicine and the patient outcome depends on the fast beginning of adequate antibiotic therapy. Until today pathogen identification is performed using conventional microbiological methods with turnaround times of at least 24 h for the first results. It was the aim of this study to investigate the potential of headspace analyses detecting bacterial species-specific patterns of volatile organic compounds (VOCs) for the rapid differentiation of HAP-relevant bacteria.\r\n \r\n \r\n Methods\r\n Eleven HAP-relevant bacteria (Acinetobacter baumanii, Acinetobacter pittii, Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus aureus, Serratia marcescens) were each grown for 6 hours in Lysogeny Broth and the headspace over the grown cultures was investigated using multi-capillary column-ion mobility spectrometry (MCC-IMS) to detect differences in the VOC composition between the bacteria in the panel. Peak areas with changing signal intensities were statistically analysed, including significance testing using one-way ANOVA or Kruskal-Wallis test (p < 0.05).\r\n \r\n \r\n Results\r\n 30 VOC signals (23 in the positive ion mode and 7 in the negative ion mode of the MCC-IMS) showed statistically significant differences in at least one of the investigated bacteria. The VOC patterns of the bacteria within the HAP panel differed substantially and allowed species differentiation.\r\n \r\n \r\n Conclusions\r\n MCC-IMS headspace analyses allow differentiation of bacteria within HAP-relevant panel after 6 h of incubation in a complex fluid growth medium. The method has the potential to be developed towards a feasible point-of-care diagnostic tool for pathogen differentiation on HAP."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.citation","BMC Microbiology. 2021 Feb 28;21(1):69"],["dc.identifier.doi","10.1186/s12866-021-02102-8"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17742"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82517"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112945"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","BioMed Central"],["dc.relation.eissn","1471-2180"],["dc.rights","CC BY 4.0"],["dc.rights.holder","The Author(s)"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject","Pneumonia"],["dc.subject","Microbiological techniques"],["dc.subject","Volatile organic compound"],["dc.subject","Metabolite"],["dc.subject","Ion mobility spectrometry"],["dc.title","Headspace analyses using multi-capillary column-ion mobility spectrometry allow rapid pathogen differentiation in hospital-acquired pneumonia relevant bacteria"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","46"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Intensive Care Medicine Experimental"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Cambiaghi, Barbara"],["dc.contributor.author","Vasques, Francesco"],["dc.contributor.author","Mörer, Onnen"],["dc.contributor.author","Ritter, Christian"],["dc.contributor.author","Mauri, Tommaso"],["dc.contributor.author","Kunze-Szikszay, Nils"],["dc.contributor.author","Holke, Karin"],["dc.contributor.author","Collino, Francesca"],["dc.contributor.author","Maiolo, Giorgia"],["dc.contributor.author","Rapetti, Francesca"],["dc.contributor.author","Schulze-Kalthoff, Elias"],["dc.contributor.author","Tonetti, Tommaso"],["dc.contributor.author","Hahn, Günter"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Gattinoni, Luciano"],["dc.date.accessioned","2020-12-10T18:41:24Z"],["dc.date.available","2020-12-10T18:41:24Z"],["dc.date.issued","2017"],["dc.description.abstract","Abstract Background Severe hypoperfusion can cause lung damage. We studied the effects of regional perfusion block in normal lungs and in the lungs that had been conditioned by lavage with 500 ml saline and high V T (20 ml kg−1) ventilation. Methods Nineteen pigs (61.2 ± 2.5 kg) were randomized to five groups: controls (n = 3), the right lower lobe block alone (n = 3), lavage and high V T (n = 4), lung lavage, and high V T plus perfusion block of the right (n = 5) or left (n = 4) lower lobe. Gas exchange, respiratory mechanics, and hemodynamics were measured hourly. After an 8-h observation period, CT scans were obtained at 0 and 15 cmH2O airway pressure. Results Perfusion block did not damage healthy lungs. In conditioned lungs, the left perfusion block caused more edema in the contralateral lung (777 ± 62 g right lung vs 484 ± 204 g left; p < 0.05) than the right perfusion block did (581 ± 103 g right lung vs 484 ± 204 g left; p n.s.). The gas/tissue ratio, however, was similar (0.5 ± 0.3 and 0.8 ± 0.5; p n.s.). The lobes with perfusion block were not affected (gas/tissue ratio right 1.6 ± 0.9; left 1.7 ± 0.5, respectively). Pulmonary artery pressure, PaO2/FiO2, dead space, and lung mechanics were more markedly affected in animals with left perfusion block, while the gas/tissue ratios were similar in the non-occluded lobes. Conclusions The right and left perfusion blocks caused the same “intensity” of edema in conditioned lungs. The total amount of edema in the two lungs differed because of differences in lung size. If capillary permeability is altered, increased blood flow may induce or increase edema."],["dc.identifier.doi","10.1186/s40635-017-0161-2"],["dc.identifier.eissn","2197-425X"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15183"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77572"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Springer"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Effects of regional perfusion block in healthy and injured lungs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","163"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Anesthesiology"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Perl, Thorsten"],["dc.contributor.author","Kunze-Szikszay, N."],["dc.contributor.author","Bräuer, A."],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Roy, T."],["dc.contributor.author","Kerpen, K."],["dc.contributor.author","Telgheder, U."],["dc.date.accessioned","2021-06-01T10:48:02Z"],["dc.date.accessioned","2022-08-16T12:37:25Z"],["dc.date.available","2021-06-01T10:48:02Z"],["dc.date.available","2022-08-16T12:37:25Z"],["dc.date.issued","2021-05-27"],["dc.date.updated","2022-07-29T12:00:16Z"],["dc.description.abstract","Abstract\r\n \r\n Background\r\n Fluid warming, recommended for fluid rates of > 500 ml h-1, is an integral part of patient temperature management strategies. Fluid warming devices using an uncoated aluminium containing heating element have been reported to liberate aluminium resulting in critical aluminium concentrations in heated fluids. We investigated saline solution (0.9%), artificially spiked with organic acids to determine the influence of fluid composition on aluminium release using the uncoated enFlow® device. Additionally, the Level1® as a high volume fluid warming device and the ThermoSens® device were investigated with artificial spiked fluid at high risk for aluminum release and a clinically used crystalloid solution.\r\n \r\n \r\n Results\r\n Saline solution spiked with lactate more than acetate, especially at a non neutral pH, led to high aluminium release. Next to the enFlow® device, aluminium release was observed for the Level1® device, but not for the coated ThermoSens®-device.\r\n \r\n \r\n Conclusion\r\n Uncoated aluminium containing fluid warming devices lead to potentially toxic levels of aluminium in heated fluids, especially in fluids with non-neutral pH containing organic acids and their salts like balanced electrolyte solutions."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.citation","BMC Anesthesiology. 2021 May 27;21(1):163"],["dc.identifier.doi","10.1186/s12871-021-01378-7"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85808"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112736"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1471-2253"],["dc.rights","CC BY 4.0"],["dc.rights.holder","The Author(s)"],["dc.subject","Hypothermia"],["dc.subject","Prevention"],["dc.subject","Warming techniques"],["dc.subject","Fluid warming"],["dc.title","Aluminium release and fluid warming: provocational setting and devices at risk"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Antibiotics"],["dc.bibliographiccitation.volume","11"],["dc.contributor.affiliation","Euler, Maximilian; 1Department of Anesthesiology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany; isabell.eickel@med.uni-goettingen.de (I.E.); johannes.wieditz@med.uni-goettingen.de (J.W.); konrad.meissner@med.uni-goettingen.de (K.M.); nils.kunze@med.uni-goettingen.de (N.K.-S.)"],["dc.contributor.affiliation","Perl, Thorsten; 2Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany; thorsten.perl@med.uni-goettingen.de"],["dc.contributor.affiliation","Eickel, Isabell; 1Department of Anesthesiology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany; isabell.eickel@med.uni-goettingen.de (I.E.); johannes.wieditz@med.uni-goettingen.de (J.W.); konrad.meissner@med.uni-goettingen.de (K.M.); nils.kunze@med.uni-goettingen.de (N.K.-S.)"],["dc.contributor.affiliation","Dudakova, Anna; 3Department of Medical Microbiology and Virology, University Medical Center Göttingen, Kreuzbergring 57, 37075 Göttingen, Germany; anna.dudakova@med.uni-goettingen.de (A.D.); esther.maguillarosado@med.uni-goettingen.de (E.M.R.)"],["dc.contributor.affiliation","Maguilla Rosado, Esther; 3Department of Medical Microbiology and Virology, University Medical Center Göttingen, Kreuzbergring 57, 37075 Göttingen, Germany; anna.dudakova@med.uni-goettingen.de (A.D.); esther.maguillarosado@med.uni-goettingen.de (E.M.R.)"],["dc.contributor.affiliation","Drees, Carolin; 4Leibniz-Institute for Analytical Sciences—ISAS—e.V., Bunsen-Kirchhoff-Straße 11, 44139 Dortmund, Germany; drees@medecon.ruhr (C.D.); w.vautz@ion-gas.de (W.V.)"],["dc.contributor.affiliation","Vautz, Wolfgang; 4Leibniz-Institute for Analytical Sciences—ISAS—e.V., Bunsen-Kirchhoff-Straße 11, 44139 Dortmund, Germany; drees@medecon.ruhr (C.D.); w.vautz@ion-gas.de (W.V.)"],["dc.contributor.affiliation","Wieditz, Johannes; 1Department of Anesthesiology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany; isabell.eickel@med.uni-goettingen.de (I.E.); johannes.wieditz@med.uni-goettingen.de (J.W.); konrad.meissner@med.uni-goettingen.de (K.M.); nils.kunze@med.uni-goettingen.de (N.K.-S.)"],["dc.contributor.affiliation","Meissner, Konrad; 1Department of Anesthesiology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany; isabell.eickel@med.uni-goettingen.de (I.E.); johannes.wieditz@med.uni-goettingen.de (J.W.); konrad.meissner@med.uni-goettingen.de (K.M.); nils.kunze@med.uni-goettingen.de (N.K.-S.)"],["dc.contributor.affiliation","Kunze-Szikszay, Nils; 1Department of Anesthesiology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany; isabell.eickel@med.uni-goettingen.de (I.E.); johannes.wieditz@med.uni-goettingen.de (J.W.); konrad.meissner@med.uni-goettingen.de (K.M.); nils.kunze@med.uni-goettingen.de (N.K.-S.)"],["dc.contributor.author","Euler, Maximilian"],["dc.contributor.author","Perl, Thorsten"],["dc.contributor.author","Eickel, Isabell"],["dc.contributor.author","Dudakova, Anna"],["dc.contributor.author","Maguilla Rosado, Esther"],["dc.contributor.author","Drees, Carolin"],["dc.contributor.author","Vautz, Wolfgang"],["dc.contributor.author","Wieditz, Johannes"],["dc.contributor.author","Meissner, Konrad"],["dc.contributor.author","Kunze-Szikszay, Nils"],["dc.date.accessioned","2022-08-04T08:39:16Z"],["dc.date.available","2022-08-04T08:39:16Z"],["dc.date.issued","2022-07-23"],["dc.date.updated","2022-08-03T09:06:01Z"],["dc.description.abstract","(1) Background: Automated blood culture headspace analysis for the detection of volatile organic compounds of microbial origin (mVOC) could be a non-invasive method for bedside rapid pathogen identification. We investigated whether analyzing the gaseous headspace of blood culture (BC) bottles through gas chromatography-ion mobility spectrometry (GC-IMS) enables differentiation of infected and non-infected; (2) Methods: BC were gained out of a rabbit model, with sepsis induced by intravenous administration of E. coli (EC group; n = 6) and control group (n = 6) receiving sterile LB medium intravenously. After 10 h, a pair of blood cultures was obtained and incubated for 36 h. The headspace from aerobic and anaerobic BC was sampled every two hours using an autosampler and analyzed using a GC-IMS device. MALDI-TOF MS was performed to confirm or exclude microbial growth in BCs; (3) Results: Signal intensities (SI) of 113 mVOC peak regions were statistically analyzed. In 24 regions, the SI trends differed between the groups and were considered to be useful for differentiation. The principal component analysis showed differentiation between EC and control group after 6 h, with 62.2% of the data variance described by the principal components 1 and 2. Single peak regions, for example peak region P_15, show significant SI differences after 6 h in the anaerobic environment (p < 0.001) and after 8 h in the aerobic environment (p < 0.001); (4) Conclusions: The results are promising and warrant further evaluation in studies with an extended microbial panel and indications concerning its transferability to human samples."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)"],["dc.description.sponsorship","APC support by the Open Access Publication Funds of the Göttingen University"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3390/antibiotics11080992"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112637"],["dc.language.iso","en"],["dc.relation.eissn","2079-6382"],["dc.rights","CC BY 4.0"],["dc.title","Blood Culture Headspace Gas Analysis Enables Early Detection of Escherichia coli Bacteremia in an Animal Model of Sepsis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]