Leibing, Eric

[["dc.bibliographiccitation.firstpage","875"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","American Journal of Psychiatry"],["dc.bibliographiccitation.lastpage","881"],["dc.bibliographiccitation.volume","166"],["dc.contributor.author","Leichsenring, Falk"],["dc.contributor.author","Salzer, Simone"],["dc.contributor.author","Jaeger, Ulrich"],["dc.contributor.author","Kaechele, Horst"],["dc.contributor.author","Kreische, Reinhard"],["dc.contributor.author","Leweke, Frank"],["dc.contributor.author","Rueger, Ulrich"],["dc.contributor.author","Winkelbach, Christel"],["dc.contributor.author","Leibing, Eric"],["dc.date.accessioned","2018-11-07T11:25:48Z"],["dc.date.available","2018-11-07T11:25:48Z"],["dc.date.issued","2009"],["dc.description.abstract","Objective: While several studies have shown that cognitive-behavioral therapy (CBT) is an efficacious treatment for generalized anxiety disorder, few studies have addressed the outcome of short-term psychodynamic psychotherapy, even though this treatment is widely used. The aim of this study was to compare short-term psychodynamic psychotherapy and CBT with regard to treatment outcome in generalized anxiety disorder. Method: Patients with generalized anxiety disorder according to DSM-IV were randomly assigned to receive either CBT (N=29) or short-term psychodynamic psychotherapy (N=28). Treatments were carried out according to treatment manuals and included up to 30 weekly sessions. The primary outcome measure was the Hamilton Anxiety Rating Scale, which was applied by trained raters blind to the treatment conditions. Assessments were carried out at the completion of treatment and 6 months afterward. Results: Both CBT and short-term psychodynamic psychotherapy yielded significant, large, and stable improvements with regard to symptoms of anxiety and depression. No significant differences in outcome were found between treatments in regard to the primary outcome measure. These results were corroborated by two self-report measures of anxiety. In measures of trait anxiety, worry, and depression, however, CBT was found to be superior. Conclusions: The results suggest that CBT and short-term psychodynamic psychotherapy are beneficial for patients with generalized anxiety disorder. In future research, large-scale multicenter studies should examine more subtle differences between treatments, including differences in the patients who benefit most from each form of therapy."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft [LE 1250/1-1/1-2]"],["dc.identifier.doi","10.1176/appi.ajp.2009.09030441"],["dc.identifier.isi","000268638900009"],["dc.identifier.pmid","19570931"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6170"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56710"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Psychiatric Publishing, Inc"],["dc.relation.issn","0002-953X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Short-Term Psychodynamic Psychotherapy and Cognitive-Behavioral Therapy in Generalized Anxiety Disorder: A Randomized, Controlled Trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","126"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Psychiatry and Neuroscience"],["dc.bibliographiccitation.lastpage","131"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Irle, Eva"],["dc.contributor.author","Ruhleder, Mirjana"],["dc.contributor.author","Lange, Claudia"],["dc.contributor.author","Seidler-Brandler, Ulrich"],["dc.contributor.author","Salzer, Simone"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Weniger, Godehard"],["dc.contributor.author","Leibing, Eric"],["dc.contributor.author","Leichsenring, Falk"],["dc.date.accessioned","2018-11-07T08:45:32Z"],["dc.date.available","2018-11-07T08:45:32Z"],["dc.date.issued","2010"],["dc.description.abstract","Background: Structural and functional brain imaging studies suggest abnormalities of the amygdala and hippocampus in posttraumatic stress disorder and major depressive disorder. However, structural brain imaging studies in social phobia are lacking. Methods: In total, 24 patients with generalized social phobia (GSP) and 24 healthy controls underwent 3-dimensional structural magnetic resonance imaging of the amygdala and hippocampus and a clinical investigation. Results: Compared with controls, GSP patients had significantly reduced amygdalar (13%) and hippocampal (8%) size. The reduction in the size of the amygdala was statistically significant for men but not women. Smaller right-sided hippocampal volumes of GSP patients were significantly related to stronger disorder severity. Limitations: Our sample included only patients with the generalized subtype of social phobia. Because we excluded patients with comorbid depression, our sample may not be representative. Conclusion: We report for the first time volumetric results in patients with GSP. Future assessment of these patients will clarify whether these changes are reversed after successful treatment and whether they predict treatment response."],["dc.description.sponsorship","Ministry of Education and Research, Germany [BMBF 01GV0607]"],["dc.identifier.doi","10.1503/jpn.090041"],["dc.identifier.isi","000274851600007"],["dc.identifier.pmid","20184810"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6891"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20469"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cma-canadian Medical Assoc"],["dc.relation.issn","1180-4882"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Reduced amygdalar and hippocampal size in adults with generalized social phobia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","215"],["dc.bibliographiccitation.journal","Health and Quality of Life Outcomes"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Sonntag, Michael"],["dc.contributor.author","Konnopka, Alexander"],["dc.contributor.author","Leichsenring, Falk"],["dc.contributor.author","Salzer, Simone"],["dc.contributor.author","Beutel, Manfred E."],["dc.contributor.author","Herpertz, Stephan"],["dc.contributor.author","Hiller, Wolfgang"],["dc.contributor.author","Hoyer, Juergen"],["dc.contributor.author","Joraschky, Peter"],["dc.contributor.author","Nolting, Bjoern"],["dc.contributor.author","Poehlmann, Karin"],["dc.contributor.author","Stangier, Ulrich"],["dc.contributor.author","Strauss, Bernhard"],["dc.contributor.author","Willutzki, Ulrike"],["dc.contributor.author","Wiltink, Joerg"],["dc.contributor.author","Leibing, Eric"],["dc.contributor.author","Koenig, Hans-Helmut"],["dc.date.accessioned","2018-11-07T09:16:28Z"],["dc.date.available","2018-11-07T09:16:28Z"],["dc.date.issued","2013"],["dc.description.abstract","Objective: The aim of the study was to analyse the psychometric properties of the EQ-5D in patients with social phobia. Methods: We used a sample of 445 patients with social phobia with five measurement points over a 30 month period. The discriminative ability of the EQ-5D was analysed by comparing the patients' responses with the general population and between different disease severity levels. For test-retest reliability we assessed the level of agreement in patients' responses over time, when there was no change in the Liebowitz Social Anxiety Scale (LSAS). Construct validity was analysed by identifying correlations of the EQ-5D with more specific instruments. For responsiveness we compared the means of EQ VAS/EQ-5D index anchored on improved (deteriorated) health status and computed effect sizes as well as a receiver operating characteristic (ROC) curve. Results: Compared to the general population, patients with social phobia reported more problems in the dimensions \"usual activities\", \"pain/discomfort\", and \"anxiety/depression\" and less problems in \"mobility\" and \"self-care\". The EQ-5D was able to distinguish between different disease severity levels. The test-retest reliability was moderate (intraclass correlation coefficient > 0.6). Correlations between the EQ-5D and other instruments were mostly small except for correlations with Beck Depression Inventory. The EQ-5D index seemed to be more responsive than the EQ VAS, but with only medium effect sizes (0.5 < effect size < 0.8) in the British EQ-5D index and only significant in patients with improved health status. The ROC analysis revealed no significant results. Conclusions: The EQ-5D was moderately reliable and responsive in patients with improved health status. Construct validity was limited."],["dc.identifier.doi","10.1186/1477-7525-11-215"],["dc.identifier.isi","000330115400002"],["dc.identifier.pmid","24365384"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12495"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27941"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1477-7525"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Reliability, validity and responsiveness of the EQ-5D in assessing and valuing health status in patients with social phobia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0147165"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Wiltink, Joerg"],["dc.contributor.author","Hoyer, Juergen"],["dc.contributor.author","Beutel, Manfred E."],["dc.contributor.author","Ruckes, Christian"],["dc.contributor.author","Herpertz, Stephan"],["dc.contributor.author","Joraschky, Peter"],["dc.contributor.author","Koranyi, Susan"],["dc.contributor.author","Michal, Matthias"],["dc.contributor.author","Nolting, Bjoern"],["dc.contributor.author","Poehlmann, Karin"],["dc.contributor.author","Salzer, Simone"],["dc.contributor.author","Strauss, Bernhard"],["dc.contributor.author","Leibing, Eric"],["dc.contributor.author","Leichsenring, Falk"],["dc.date.accessioned","2018-11-07T10:19:20Z"],["dc.date.available","2018-11-07T10:19:20Z"],["dc.date.issued","2016"],["dc.description.abstract","Objectives Little is known about patient characteristics as predictors for outcome in manualized short term psychodynamic psychotherapy (PDT). No study has addressed which patient variables predict outcome of PDT for social anxiety disorder. Research Design and Methods In the largest multicenter trial on psychotherapy of social anxiety (SA) to date comparing cognitive therapy, PDT and wait list condition N = 230 patients were assigned to receive PDT, of which N = 166 completed treatment. Treatment outcome was assessed based on diverse parameters such as endstate functioning, remission, response, and drop-out. The relationship between patient characteristics (demographic variables, mental co-morbidity, personality, interpersonal problems) and outcome was analysed using logistic and linear regressions. Results Pre-treatment SA predicted up to 39 percent of variance of outcome. Only few additional baseline characteristics predicted better treatment outcome (namely, lower comorbidity and interpersonal problems) with a limited proportion of incremental variance (5.5 to 10 percent), while, e.g., shame, self-esteem or harm avoidance did not. Conclusions We argue that the central importance of pre-treatment symptom severity for predicting outcomes should advocate alternative treatment strategies (e.g. longer treatments, combination of psychotherapy and medication) in those who are most disturbed. Given the relatively small amount of variance explained by the other patient characteristics, process variables and patient-therapist interaction should additionally be taken into account in future research."],["dc.description.sponsorship","German Ministry of Education and Research (BMBF) [01GV0607]"],["dc.identifier.doi","10.1371/journal.pone.0147165"],["dc.identifier.isi","000368528400117"],["dc.identifier.pmid","26785255"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12851"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41637"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Do Patient Characteristics Predict Outcome of Psychodynamic Psychotherapy for Social Anxiety Disorder?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e0192802"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Strauß, Bernhard"],["dc.contributor.author","Altmann, Uwe"],["dc.contributor.author","Manes, Susanne"],["dc.contributor.author","Tholl, Anne"],["dc.contributor.author","Koranyi, Susan"],["dc.contributor.author","Nolte, Tobias"],["dc.contributor.author","Beutel, Manfred E."],["dc.contributor.author","Wiltink, Jörg"],["dc.contributor.author","Herpertz, Stephan"],["dc.contributor.author","Hiller, Wolfgang"],["dc.contributor.author","Hoyer, Jürgen"],["dc.contributor.author","Joraschky, Peter"],["dc.contributor.author","Nolting, Björn"],["dc.contributor.author","Ritter, Viktoria"],["dc.contributor.author","Stangier, Ulrich"],["dc.contributor.author","Willutzki, Ulrike"],["dc.contributor.author","Salzer, Simone"],["dc.contributor.author","Leibing, Eric"],["dc.contributor.author","Leichsenring, Falk"],["dc.contributor.author","Kirchmann, Helmut"],["dc.contributor.editor","Moitra, Ethan"],["dc.date.accessioned","2020-12-10T18:42:05Z"],["dc.date.available","2020-12-10T18:42:05Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1371/journal.pone.0192802"],["dc.identifier.eissn","1932-6203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15677"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77803"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Changes of attachment characteristics during psychotherapy of patients with social anxiety disorder: Results from the SOPHO-Net trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","223"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Psychotherapy and Psychosomatics"],["dc.bibliographiccitation.lastpage","233"],["dc.bibliographiccitation.volume","87"],["dc.contributor.author","Salzer, Simone"],["dc.contributor.author","Stefini, Annette"],["dc.contributor.author","Kronmüller, Klaus-Thomas"],["dc.contributor.author","Leibing, Eric"],["dc.contributor.author","Leichsenring, Falk"],["dc.contributor.author","Henningsen, Peter"],["dc.contributor.author","Peseschkian, Hamid"],["dc.contributor.author","Reich, Günter"],["dc.contributor.author","Rosner, Rita"],["dc.contributor.author","Ruhl, Uwe"],["dc.contributor.author","Schopf, Yvonne"],["dc.contributor.author","Steinert, Christiane"],["dc.contributor.author","Vonderlin, Eva"],["dc.contributor.author","Steil, Regina"],["dc.date.accessioned","2020-12-10T18:37:49Z"],["dc.date.available","2020-12-10T18:37:49Z"],["dc.date.issued","2018"],["dc.description.abstract","Background: Although social anxiety disorder (SAD) has an early onset and is frequently found in adolescence, evidence for psychotherapeutic treatments of SAD in adolescents is rather scarce. Within the Social Phobia Psychotherapy Research Network (SOPHO-NET), we examined the efficacy of cognitive-behavioral (CBT) and psychodynamic therapy (PDT) compared to a waiting list (WL) in these patients. Methods: In a multicenter randomized controlled superiority trial, 107 patients, aged 14–20 years, were randomized to CBT (n = 34), PDT (n = 34), or WL (n = 39). Assessments were made at baseline, at the end of treatment, and 6 and 12 months after termination. The Liebowitz Social Anxiety Scale for Children and Adolescents (LSAS-CA) applied by raters masked to the treatment condition was used as the primary outcome. As secondary outcomes, rates of response and remission and the Social Phobia Anxiety Inventory (SPAI) were used. Results: Both treatments were superior to WL in the LSAS-CA (CBT: p = 0.0112, d = 0.61, 95% CI 0.14–1.08; PDT: p = 0.0261, d = 0.53, 95% CI 0.06–1.00). At the end of treatment, response rates were 66, 54, and 20% for CBT, PDT, and WL. The corresponding remission rates were 47, 34, and 6%, respectively. CBT and PDT were significantly superior to WL regarding remission (CBT: p = 0.0009, h = 1.0; PDT: p = 0.0135, h = 0.74), response (CBT: p = 0.0004, h = 0.97; PDT: p = 0.0056, h = 0.72), and the SPAI (CBT: p = 0.0021, d = 0.75, 95% CI 0.27–1.22; PDT: p = 0.0060, d = 0.66, 95% CI 0.19–1.13). Treatment effects were stable at 6- and 12-month follow-ups. Conclusions: These results are comparable to the large SOPHO-NET trial in adults (n = 495). Early treatments for social anxiety are needed in order to prevent chronic manifestation of SAD."],["dc.identifier.doi","10.1159/000488990"],["dc.identifier.eissn","1423-0348"],["dc.identifier.issn","0033-3190"],["dc.identifier.pmid","29895001"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77106"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","S. Karger AG"],["dc.relation.eissn","1423-0348"],["dc.relation.issn","0033-3190"],["dc.rights","https://www.karger.com/Services/SiteLicenses"],["dc.title","Cognitive-Behavioral and Psychodynamic Therapy in Adolescents with Social Anxiety Disorder: A Multicenter Randomized Controlled Trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]