Petzke, Frank

[["dc.bibliographiccitation.artnumber","e0182207"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Schäfer, Axel Georg Meender"],["dc.contributor.author","Joos, Leonie Johanna"],["dc.contributor.author","Roggemann, Katharina"],["dc.contributor.author","Waldvogel-Röcker, Kerstin"],["dc.contributor.author","Pfingsten, Michael"],["dc.contributor.author","Petzke, Frank"],["dc.date.accessioned","2019-07-09T11:44:35Z"],["dc.date.available","2019-07-09T11:44:35Z"],["dc.date.issued","2017"],["dc.description.abstract","OBJECTIVES: Central sensitization (CS) is regarded as an important contributing factor for chronification of musculoskeletal pain (MSP). It is crucial to identify CS, as targeted multimodal treatment may be indicated. The primary objective of this study was therefore to explore pain experience of individuals with MSP+CS in order to gain a better understanding of symptoms in relation to CS from a patient perspective. The secondary objective was to investigate whether pain experiences of patients with MSP+CS differ from those of individuals with neuropathic pain (NP). METHODS: We conducted a comparative Group Delphi Study including patients with MSP+CS and neuropathic pain (NP). 13 guiding questions were used to gather information about sensory discriminatory, affective and associated bodily, mental and emotional phenomena related to the pain experience of patients. Descriptions were categorized using qualitative content analysis. Additionally, patients completed several pain related questionnaires. RESULTS: Nine participants with MSP+CS and nine participants with NP participated. The Delphi procedure revealed three main themes: psycho-emotional factors, bodily factors and environmental factors. Descriptions of patients with MSP+CS showed a complex picture, psycho-emotional factors seem to have a considerable impact on pain provocation, aggravation and relief. Impairments associated with mental ability and psyche affected many aspects of daily life. In contrast, descriptions of patients with NP revealed a rather mechanistic and bodily oriented pain experience. DISCUSSION: Patients with MSP+CS reported distinct features in relation to their pain that were not captured with current questionnaires. Insight in patient's pain experience may help to choose and develop appropriate diagnostic instruments."],["dc.description.abstract","OBJECTIVES: Central sensitization (CS) is regarded as an important contributing factor for chronification of musculoskeletal pain (MSP). It is crucial to identify CS, as targeted multimodal treatment may be indicated. The primary objective of this study was therefore to explore pain experience of individuals with MSP+CS in order to gain a better understanding of symptoms in relation to CS from a patient perspective. The secondary objective was to investigate whether pain experiences of patients with MSP+CS differ from those of individuals with neuropathic pain (NP). METHODS: We conducted a comparative Group Delphi Study including patients with MSP+CS and neuropathic pain (NP). 13 guiding questions were used to gather information about sensory discriminatory, affective and associated bodily, mental and emotional phenomena related to the pain experience of patients. Descriptions were categorized using qualitative content analysis. Additionally, patients completed several pain related questionnaires. RESULTS: Nine participants with MSP+CS and nine participants with NP participated. The Delphi procedure revealed three main themes: psycho-emotional factors, bodily factors and environmental factors. Descriptions of patients with MSP+CS showed a complex picture, psycho-emotional factors seem to have a considerable impact on pain provocation, aggravation and relief. Impairments associated with mental ability and psyche affected many aspects of daily life. In contrast, descriptions of patients with NP revealed a rather mechanistic and bodily oriented pain experience. DISCUSSION: Patients with MSP+CS reported distinct features in relation to their pain that were not captured with current questionnaires. Insight in patient's pain experience may help to choose and develop appropriate diagnostic instruments."],["dc.identifier.doi","10.1371/journal.pone.0182207"],["dc.identifier.pmid","28796805"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14821"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59039"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.subject.mesh","Adult"],["dc.subject.mesh","Aged"],["dc.subject.mesh","Central Nervous System Sensitization"],["dc.subject.mesh","Chronic Pain"],["dc.subject.mesh","Cross-Sectional Studies"],["dc.subject.mesh","Delphi Technique"],["dc.subject.mesh","Emotions"],["dc.subject.mesh","Female"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Male"],["dc.subject.mesh","Middle Aged"],["dc.subject.mesh","Musculoskeletal Pain"],["dc.subject.mesh","Neuralgia"],["dc.subject.mesh","Pain Measurement"],["dc.subject.mesh","Qualitative Research"],["dc.subject.mesh","Quality of Life"],["dc.title","Pain experiences of patients with musculoskeletal pain + central sensitization: A comparative Group Delphi Study."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0186400"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Gram, Mikkel"],["dc.contributor.author","Erlenwein, Joachim"],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Falla, Deborah"],["dc.contributor.author","Przemeck, Michael"],["dc.contributor.author","Emons, Miriam I."],["dc.contributor.author","Reuster, Michael"],["dc.contributor.author","Olesen, Søren S."],["dc.contributor.author","Drewes, Asbjørn M."],["dc.date.accessioned","2019-07-09T11:44:41Z"],["dc.date.available","2019-07-09T11:44:41Z"],["dc.date.issued","2017"],["dc.description.abstract","BACKGROUND: Experimental models have been used extensively to evaluate pain using e.g., visual analogue scales or electroencephalography (EEG). Stimulation using tonic pain has been shown to better mimic the unpleasantness of chronic pain, but has mainly been evoked by non-clinical stimuli. This study aims to, evaluate the EEG during clinical pain in patients scheduled for total hip replacement with control and resting conditions. METHODS: The hip scheduled for replacement was moved by the examiner to evoke pain for 30 seconds while recording EEG. The control condition entailed movement of the opposite hip in a similar fashion and holding it for 30 seconds. In addition, EEG was recorded during the resting condition with open eyes. The relative spectral content was calculated from the EEG as well as functional connectivity using phase-lag index for frequency bands delta (1-4Hz), theta (4-8Hz), alpha (8-12Hz) and beta (12-32Hz). A mixed model was used for statistical comparison between the three recording conditions. RESULTS: Spectral content differed between conditions in all bands. Functional connectivity differed in delta and theta frequency bands. Post-hoc analysis revealed differences between the painful and control condition in delta, theta and beta for spectral content. Pain during the hip rotation was correlated to the theta (r = -0.24 P = 0.03) and beta (r = 0.25 P = 0.02) content in the EEG. CONCLUSION: EEG differences during hip movements in the affected and unaffected hip appeared in the spectral beta and theta content. This was correlated to the reported pain perceived, pointing towards pain specific brain activity related to clinical pain."],["dc.identifier.doi","10.1371/journal.pone.0186400"],["dc.identifier.pmid","29084278"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14866"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59066"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.subject.mesh","Animals"],["dc.subject.mesh","Cats"],["dc.subject.mesh","Cerebral Cortex"],["dc.subject.mesh","Electroencephalography"],["dc.subject.mesh","Female"],["dc.subject.mesh","Guinea Pigs"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Male"],["dc.subject.mesh","Osteoarthritis, Hip"],["dc.subject.mesh","Pain"],["dc.title","The cortical responses to evoked clinical pain in patients with hip osteoarthritis."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","455"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Current Rheumatology Reports"],["dc.bibliographiccitation.lastpage","461"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Pavlaković, Goran"],["dc.contributor.author","Petzke, Frank"],["dc.date.accessioned","2019-07-09T11:53:03Z"],["dc.date.available","2019-07-09T11:53:03Z"],["dc.date.issued","2010"],["dc.description.abstract","Quantitative sensory testing (QST) is a noninvasive method of assessing sensory and pain perception that has been used in the past 30 years primarily for analysis of cutaneous and mucosal perception. In recent years, several published studies have demonstrated that QST may be useful in the analysis of painful musculoskeletal disorders as well. Based on the results of these studies, it can be postulated that QST may be useful in the analysis of the pathogenesis, classification, and differential diagnosis of musculoskeletal disorders. However, due to the diverse ethiopathogenetic basis of these disorders, a broad range of QST test batteries may be necessary to analyze the various musculoskeletal disease entities. This review analyzes published studies on this subject and summarizes current information on altered sensory and pain perception available for some of the most common musculoskeletal disorders. At present, QST remains primarily a research tool but may be useful in differential diagnosis in indicating the presence of central sensitization and for clinical monitoring of disease progression or treatment response."],["dc.identifier.doi","10.1007/s11926-010-0131-0"],["dc.identifier.fs","577728"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6827"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60332"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Current Science Inc."],["dc.publisher.place","New York"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","The Role of Quantitative Sensory Testing in the Evaluation of Musculoskeletal Pain Conditions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e840"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Pain Reports"],["dc.bibliographiccitation.lastpage","9"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Bock, Frietjof"],["dc.contributor.author","Hüppe, Michael"],["dc.contributor.author","Nothacker, Monika"],["dc.contributor.author","Norda, Heike"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Schiltenwolf, Marcus"],["dc.contributor.author","Schuler, Matthias"],["dc.contributor.author","Tölle, Thomas"],["dc.contributor.author","Viniol, Anika"],["dc.contributor.author","Häuser, Winfried"],["dc.date.accessioned","2020-09-16T09:31:25Z"],["dc.date.accessioned","2021-10-27T13:22:19Z"],["dc.date.available","2020-09-16T09:31:25Z"],["dc.date.available","2021-10-27T13:22:19Z"],["dc.date.issued","2020"],["dc.description.abstract","Introduction: The opioid epidemic in North America challenges national guidelines worldwide to define the importance of opioids for the management of chronic noncancer pain (CNCP). Methods: The second update of the German guidelines on long-term opioid therapy for CNCP was developed by 26 scientific associations and 2 patient self-help organizations. A systematic literature search in CENTRAL, Medline, and Scopus (to May 2019) was performed. Meta-analyses of randomized controlled trials and open-label extension studies with opioids for CNCP were conducted. Levels of evidence were assigned according to the Oxford Centre for Evidence-Based Medicine classification system. The formulation and strength of recommendations were established by multistep formalized procedures to reach a consensus according to German Association of the Medical Scientific Societies regulations. The guidelines underwent external review by 4 experts and public commentary. Results: Opioids are one drug-based treatment option for short- (4–12 weeks), intermediate- (13–26 weeks), and long-term (>26 weeks) therapy of chronic pain in osteoarthritis, diabetic polyneuropathy, postherpetic neuralgia, and low back pain. Contraindications are primary headaches, functional somatic syndromes, and mental disorders with the (cardinal) symptom of pain. For specified other clinical pain conditions, short- and long-term therapy with opioids should be evaluated on an individual basis. Long-term therapy with opioids is associated with relevant risks. Conclusion: Responsible application of opioids requires consideration of possible indications and contraindications, as well as regular assessment of clinical response and adverse effects. Neither uncritical opioid prescription nor general rejection of opioids is justified in patients with CNCP."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2020"],["dc.identifier.doi","10.1097/PR9.0000000000000840"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17549"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92085"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.eissn","2471-2531"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.relation.orgunit","Klinik für Anästhesiologie"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Long-term opioid therapy for chronic noncancer pain: second update of the German guidelines"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]