Petzke, Frank

[["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Diagnostics"],["dc.bibliographiccitation.volume","12"],["dc.contributor.affiliation","Dieterich, Angela V.; 1Physiotherapy, Faculty of Health, Security, Society, Furtwangen University, 78120 Furtwangen im Schwarzwald, Germany"],["dc.contributor.affiliation","Yavuz, Utku Şükrü; 2Biomedical Signals and Systems, University of Twente, 7522 NB Enschede, The Netherlands; s.u.yavuz@utwente.nl"],["dc.contributor.affiliation","Petzke, Frank; 3Pain Clinic, Department of Anesthesiology, University Medical Center, 37075 Göttingen, Germany; frank.petzke@med.uni-goettingen.de"],["dc.contributor.affiliation","Nordez, Antoine; 4Movement-Interactions-Performance, Nantes Université, EA 4334, F-44000 Nantes, France; antoine.nordez@univ-nantes.fr"],["dc.contributor.author","Dieterich, Angela V."],["dc.contributor.author","Yavuz, Utku Şükrü"],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Nordez, Antoine"],["dc.date.accessioned","2022-08-04T08:37:27Z"],["dc.date.available","2022-08-04T08:37:27Z"],["dc.date.issued","2022-07-23"],["dc.date.updated","2022-08-03T10:42:19Z"],["dc.description.abstract","Identifying the objective stiffness of the neck muscles facilitates the early and specific diagnosis of neck pain and targeted therapy. However, individual variation in the muscle shear modulus obscures differences between healthy and diseased individuals. Normalization may improve the comparability between individuals. The shear modulus at different functional tasks served as a reference for normalizing the neck muscles’ shear modulus of 38 women, 20 with chronic neck pain and 18 asymptomatic. Reference tasks were maximal voluntary contraction, relaxed sitting, prone head lift, balancing 1 kg on the head, and neck extension at 48 N. The effects of normalization on within-group variation and between-group differences were compared. Normalization with maximal voluntary contraction was discarded due to imaging problems. Normalization with relaxed sitting, prone head lift, balancing 1 kg, and neck extension at 48 N reduced within-group variation, by 23.2%, 26.8%, 11.6%, and 33.6%, respectively. All four normalization approaches reduced the p-values when testing for between-group differences. For the pain group, normalization with relaxed sitting and head lift indicated less normalized muscle stiffness, while normalization with balancing 1 kg and extension at 48 N indicated higher stiffness. The contradictory results are explainable by non-significant group differences in the reference tasks. Normalization of the muscle shear modulus is effective to reduce within-group variation, but a trustworthy normalization approach for group comparisons has yet to be identified."],["dc.description.sponsorship","Baden-Württemberg Ministry of Science, Research and Culture"],["dc.description.sponsorship","Institute of Applied Research of Furtwangen University"],["dc.identifier.doi","10.3390/diagnostics12081791"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112634"],["dc.language.iso","en"],["dc.relation.eissn","2075-4418"],["dc.rights","CC BY 4.0"],["dc.title","Assessment of Neck Muscle Shear Modulus Normalization in Women with and without Chronic Neck Pain"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","42011"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Dieterich, Angela V."],["dc.contributor.author","Botter, Alberto"],["dc.contributor.author","Vieira, Taian Martins"],["dc.contributor.author","Peolsson, Anneli"],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Davey, Paul"],["dc.contributor.author","Falla, Deborah"],["dc.date.accessioned","2018-11-07T10:27:32Z"],["dc.date.available","2018-11-07T10:27:32Z"],["dc.date.issued","2017"],["dc.description.abstract","Delayed onset of muscle activation can be a descriptor of impaired motor control. Activation onset can be estimated from electromyography (EMG)-registered muscle excitation and from ultrasound-registered muscle motion, which enables non-invasive measurements in deep muscles. However, in voluntary activation, EMG-and ultrasound-detected activation onsets may not correspond. To evaluate this, ten healthy men performed isometric elbow flexion at 20% to 70% of their maximal force. Utilising a multi-channel electrode transparent to ultrasound, EMG and M(otion)-mode ultrasound were recorded simultaneously over the biceps brachii muscle. The time intervals between automated and visually estimated activation onsets were correlated with the regional variation of EMG and muscle motion onset, contraction level and speed. Automated and visual onsets indicated variable time intervals between EMG-and motion onset, median (interquartile range) 96 (121) ms and 48 (72) ms, respectively. In 17% (computed analysis) or 23% (visual analysis) of trials, motion onset was detected before local EMG onset. Multi-channel EMG and M-mode ultrasound revealed regional differences in activation onset, which decreased with higher contraction speed (Spearman rho >= 0.45, P < 0.001). In voluntary activation the heterogeneous motor unit recruitment together with immediate motion transmission may explain the high variation of the time intervals between local EMG-and ultrasound-detected activation onset."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2017"],["dc.identifier.doi","10.1038/srep42011"],["dc.identifier.isi","000393550900001"],["dc.identifier.pmid","28176821"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14273"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43250"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Nature Publishing Group"],["dc.relation.issn","2045-2322"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Spatial variation and inconsistency between estimates of onset of muscle activation from EMG and ultrasound"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","231"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Der Schmerz"],["dc.bibliographiccitation.lastpage","238"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Eich, W."],["dc.contributor.author","Baer, K.-J."],["dc.contributor.author","Bernateck, M."],["dc.contributor.author","Burgmer, Markus"],["dc.contributor.author","Dexl, C."],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Sommer, C."],["dc.contributor.author","Winkelmann, Alexander"],["dc.contributor.author","Haeuser, Winfried"],["dc.date.accessioned","2018-11-07T10:23:08Z"],["dc.date.available","2018-11-07T10:23:08Z"],["dc.date.issued","2017"],["dc.description.abstract","The regular update of the guidelines on fibromyalgia syndrome, AWMF number 145/004, was scheduled for April 2017. The guidelines were developed by 13 scientific societies and 2 patient self-help organizations coordinated by the German Pain Society. Working groups (n =8) with a total of 42 members were formed balanced with respect to gender, medical expertise, position in the medical or scientific hierarchy and potential conflicts of interest. A systematic search of the literature from December 2010 to May 2016 was performed in the Cochrane library, MEDLINE, PsycINFO and Scopus databases. Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine version 2009. The strength of recommendations was achieved by multiple step formalized procedures to reach a consensus. The guidelines were reviewed and approved by the board of directors of the societies engaged in the development of the guidelines. The clinical diagnosis of fibromyalgia syndrome can be established by the American College of Rheumatology (ACR) 1990 classification criteria (with examination of tender points) or without the examination of tender points by the modified preliminary diagnostic ACR 2010 or 2011 criteria."],["dc.identifier.doi","10.1007/s00482-017-0200-7"],["dc.identifier.isi","000402959300003"],["dc.identifier.pmid","28421273"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14720"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42401"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.relation.haserratum","/handle/2/70861"],["dc.relation.issn","1432-2129"],["dc.relation.issn","0932-433X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Definition, classification, clinical diagnosis and prognosis of fibromyalgia syndrome. Updated guidelines 2017 and overview of systematic review articles"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0182207"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Schäfer, Axel Georg Meender"],["dc.contributor.author","Joos, Leonie Johanna"],["dc.contributor.author","Roggemann, Katharina"],["dc.contributor.author","Waldvogel-Röcker, Kerstin"],["dc.contributor.author","Pfingsten, Michael"],["dc.contributor.author","Petzke, Frank"],["dc.date.accessioned","2019-07-09T11:44:35Z"],["dc.date.available","2019-07-09T11:44:35Z"],["dc.date.issued","2017"],["dc.description.abstract","OBJECTIVES: Central sensitization (CS) is regarded as an important contributing factor for chronification of musculoskeletal pain (MSP). It is crucial to identify CS, as targeted multimodal treatment may be indicated. The primary objective of this study was therefore to explore pain experience of individuals with MSP+CS in order to gain a better understanding of symptoms in relation to CS from a patient perspective. The secondary objective was to investigate whether pain experiences of patients with MSP+CS differ from those of individuals with neuropathic pain (NP). METHODS: We conducted a comparative Group Delphi Study including patients with MSP+CS and neuropathic pain (NP). 13 guiding questions were used to gather information about sensory discriminatory, affective and associated bodily, mental and emotional phenomena related to the pain experience of patients. Descriptions were categorized using qualitative content analysis. Additionally, patients completed several pain related questionnaires. RESULTS: Nine participants with MSP+CS and nine participants with NP participated. The Delphi procedure revealed three main themes: psycho-emotional factors, bodily factors and environmental factors. Descriptions of patients with MSP+CS showed a complex picture, psycho-emotional factors seem to have a considerable impact on pain provocation, aggravation and relief. Impairments associated with mental ability and psyche affected many aspects of daily life. In contrast, descriptions of patients with NP revealed a rather mechanistic and bodily oriented pain experience. DISCUSSION: Patients with MSP+CS reported distinct features in relation to their pain that were not captured with current questionnaires. Insight in patient's pain experience may help to choose and develop appropriate diagnostic instruments."],["dc.description.abstract","OBJECTIVES: Central sensitization (CS) is regarded as an important contributing factor for chronification of musculoskeletal pain (MSP). It is crucial to identify CS, as targeted multimodal treatment may be indicated. The primary objective of this study was therefore to explore pain experience of individuals with MSP+CS in order to gain a better understanding of symptoms in relation to CS from a patient perspective. The secondary objective was to investigate whether pain experiences of patients with MSP+CS differ from those of individuals with neuropathic pain (NP). METHODS: We conducted a comparative Group Delphi Study including patients with MSP+CS and neuropathic pain (NP). 13 guiding questions were used to gather information about sensory discriminatory, affective and associated bodily, mental and emotional phenomena related to the pain experience of patients. Descriptions were categorized using qualitative content analysis. Additionally, patients completed several pain related questionnaires. RESULTS: Nine participants with MSP+CS and nine participants with NP participated. The Delphi procedure revealed three main themes: psycho-emotional factors, bodily factors and environmental factors. Descriptions of patients with MSP+CS showed a complex picture, psycho-emotional factors seem to have a considerable impact on pain provocation, aggravation and relief. Impairments associated with mental ability and psyche affected many aspects of daily life. In contrast, descriptions of patients with NP revealed a rather mechanistic and bodily oriented pain experience. DISCUSSION: Patients with MSP+CS reported distinct features in relation to their pain that were not captured with current questionnaires. Insight in patient's pain experience may help to choose and develop appropriate diagnostic instruments."],["dc.identifier.doi","10.1371/journal.pone.0182207"],["dc.identifier.pmid","28796805"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14821"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59039"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.subject.mesh","Adult"],["dc.subject.mesh","Aged"],["dc.subject.mesh","Central Nervous System Sensitization"],["dc.subject.mesh","Chronic Pain"],["dc.subject.mesh","Cross-Sectional Studies"],["dc.subject.mesh","Delphi Technique"],["dc.subject.mesh","Emotions"],["dc.subject.mesh","Female"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Male"],["dc.subject.mesh","Middle Aged"],["dc.subject.mesh","Musculoskeletal Pain"],["dc.subject.mesh","Neuralgia"],["dc.subject.mesh","Pain Measurement"],["dc.subject.mesh","Qualitative Research"],["dc.subject.mesh","Quality of Life"],["dc.title","Pain experiences of patients with musculoskeletal pain + central sensitization: A comparative Group Delphi Study."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2183"],["dc.bibliographiccitation.journal","Journal of Pain Research"],["dc.bibliographiccitation.lastpage","2193"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Erlenwein, Joachim"],["dc.contributor.author","Müller, Martin"],["dc.contributor.author","Falla, Deborah"],["dc.contributor.author","Przemeck, Michael"],["dc.contributor.author","Pfingsten, Michael"],["dc.contributor.author","Budde, Stefan"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Petzke, Frank"],["dc.date.accessioned","2020-12-10T18:43:01Z"],["dc.date.available","2020-12-10T18:43:01Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.2147/JPR.S137892"],["dc.identifier.eissn","1178-7090"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14703"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78161"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/3.0"],["dc.title","Clinical relevance of persistent postoperative pain after total hip replacement – a prospective observational cohort study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0186400"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Gram, Mikkel"],["dc.contributor.author","Erlenwein, Joachim"],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Falla, Deborah"],["dc.contributor.author","Przemeck, Michael"],["dc.contributor.author","Emons, Miriam I."],["dc.contributor.author","Reuster, Michael"],["dc.contributor.author","Olesen, Søren S."],["dc.contributor.author","Drewes, Asbjørn M."],["dc.date.accessioned","2019-07-09T11:44:41Z"],["dc.date.available","2019-07-09T11:44:41Z"],["dc.date.issued","2017"],["dc.description.abstract","BACKGROUND: Experimental models have been used extensively to evaluate pain using e.g., visual analogue scales or electroencephalography (EEG). Stimulation using tonic pain has been shown to better mimic the unpleasantness of chronic pain, but has mainly been evoked by non-clinical stimuli. This study aims to, evaluate the EEG during clinical pain in patients scheduled for total hip replacement with control and resting conditions. METHODS: The hip scheduled for replacement was moved by the examiner to evoke pain for 30 seconds while recording EEG. The control condition entailed movement of the opposite hip in a similar fashion and holding it for 30 seconds. In addition, EEG was recorded during the resting condition with open eyes. The relative spectral content was calculated from the EEG as well as functional connectivity using phase-lag index for frequency bands delta (1-4Hz), theta (4-8Hz), alpha (8-12Hz) and beta (12-32Hz). A mixed model was used for statistical comparison between the three recording conditions. RESULTS: Spectral content differed between conditions in all bands. Functional connectivity differed in delta and theta frequency bands. Post-hoc analysis revealed differences between the painful and control condition in delta, theta and beta for spectral content. Pain during the hip rotation was correlated to the theta (r = -0.24 P = 0.03) and beta (r = 0.25 P = 0.02) content in the EEG. CONCLUSION: EEG differences during hip movements in the affected and unaffected hip appeared in the spectral beta and theta content. This was correlated to the reported pain perceived, pointing towards pain specific brain activity related to clinical pain."],["dc.identifier.doi","10.1371/journal.pone.0186400"],["dc.identifier.pmid","29084278"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14866"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59066"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.subject.mesh","Animals"],["dc.subject.mesh","Cats"],["dc.subject.mesh","Cerebral Cortex"],["dc.subject.mesh","Electroencephalography"],["dc.subject.mesh","Female"],["dc.subject.mesh","Guinea Pigs"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Male"],["dc.subject.mesh","Osteoarthritis, Hip"],["dc.subject.mesh","Pain"],["dc.title","The cortical responses to evoked clinical pain in patients with hip osteoarthritis."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","417"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Journal of Pain"],["dc.bibliographiccitation.lastpage","427"],["dc.bibliographiccitation.volume","26"],["dc.contributor.affiliation","Spies, Claudia; 1\r\nDepartment of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK)\r\nCharité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin, and Berlin Institute of Health\r\nBerlin Germany"],["dc.contributor.affiliation","Denke, Claudia; 1\r\nDepartment of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK)\r\nCharité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin, and Berlin Institute of Health\r\nBerlin Germany"],["dc.contributor.affiliation","Meerpohl, Joerg J.; 2\r\nInstitute for Evidence in Medicine (for Cochrane Germany Foundation)\r\nMedical Center & Faculty of Medicine\r\nUniversity of Freiburg\r\nFreiburg Germany"],["dc.contributor.affiliation","Donner‐Banzhoff, Norbert; 4\r\nDepartment of Primary Care\r\nPhillips University Marburg\r\nMarburg Germany"],["dc.contributor.affiliation","Petzke, Frank; 5\r\nPain Clinic\r\nDepartment of Anesthesiology\r\nUniversitätsmedizin Göttingen\r\nGöttingen Germany"],["dc.contributor.affiliation","Hertwig, Ralph; 6\r\nCenter for Adaptive Rationality\r\nMax‐Planck‐Institut für Bildungsforschung\r\nBerlin Germany"],["dc.contributor.affiliation","Schäfer, Michael; 1\r\nDepartment of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK)\r\nCharité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin, and Berlin Institute of Health\r\nBerlin Germany"],["dc.contributor.affiliation","Wegwarth, Odette; 6\r\nCenter for Adaptive Rationality\r\nMax‐Planck‐Institut für Bildungsforschung\r\nBerlin Germany"],["dc.contributor.author","Schulte, Erika"],["dc.contributor.author","Spies, Claudia"],["dc.contributor.author","Denke, Claudia"],["dc.contributor.author","Meerpohl, Joerg J."],["dc.contributor.author","Donner‐Banzhoff, Norbert"],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Hertwig, Ralph"],["dc.contributor.author","Schäfer, Michael"],["dc.contributor.author","Wegwarth, Odette"],["dc.date.accessioned","2021-12-01T09:23:21Z"],["dc.date.available","2021-12-01T09:23:21Z"],["dc.date.issued","2021"],["dc.date.updated","2022-03-21T11:02:47Z"],["dc.description.abstract","Abstract Background Strong opioids can have unintended effects. Clinical studies of strong opioids mainly report physical side effects, psychiatric or opioid use disorders. To date, too little attention has been paid to the psychological effects of opioids to treat patients with chronic noncancer pain (CNCP). This study aims to identify and measure (i) the nature and frequency of physical and psychological effects and (ii) the degree of physician counseling of patients with CNCP taking strong opioids. Methods Within a cross‐sectional survey—conducted as part of a randomised controlled online intervention trial (ERONA [Experiencing the risk of overusing opioids among patients with chronic non‐cancer pain in ambulatory care])—300 German CNCP patients were surveyed via patient‐reported outcome measures regarding on both the side effects from their use of strong opioids as well as their counselling experience. Results Among the patients’ reported effects, the psychological outcomes of the opioids in CNCP were: feeling relaxed (84%), fatigue (76%), dizziness (57%), listlessness (37%), difficulty with mental activities (23%), dulled emotions (17%) and poor memory (17%). Ninety‐two per cent of the patients reported having received information about opioid effects, and 46% had discussed cessation of the opioid medication with their physicians before commencing the prescription. Conclusions In addition to the well‐known physical side effects, patients with CNCP taking strong opioids experience significant psychological effects. In view of these effects, discontinuation of opioid therapy should be discussed early to ensure their benefits do not outweigh their harm. Significance In this study, patients with non‐cancer pain notice that opioids they have taken do not only cause physical side effects but also may have an impact on their psyche and their emotions and, thus, may also affect quality of life substantially. Clinical trial number: DRKS00020358."],["dc.description.sponsorship","German Federal Ministry of Health (BMG) http://dx.doi.org/10.13039/501100003107"],["dc.identifier.doi","10.1002/ejp.1868"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/94627"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-478"],["dc.relation.eissn","1532-2149"],["dc.relation.issn","1090-3801"],["dc.rights","This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made."],["dc.title","Patients’ self‐reported physical and psychological effects of opioid use in chronic noncancer pain—A retrospective cross‐sectional analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","455"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Current Rheumatology Reports"],["dc.bibliographiccitation.lastpage","461"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Pavlaković, Goran"],["dc.contributor.author","Petzke, Frank"],["dc.date.accessioned","2019-07-09T11:53:03Z"],["dc.date.available","2019-07-09T11:53:03Z"],["dc.date.issued","2010"],["dc.description.abstract","Quantitative sensory testing (QST) is a noninvasive method of assessing sensory and pain perception that has been used in the past 30 years primarily for analysis of cutaneous and mucosal perception. In recent years, several published studies have demonstrated that QST may be useful in the analysis of painful musculoskeletal disorders as well. Based on the results of these studies, it can be postulated that QST may be useful in the analysis of the pathogenesis, classification, and differential diagnosis of musculoskeletal disorders. However, due to the diverse ethiopathogenetic basis of these disorders, a broad range of QST test batteries may be necessary to analyze the various musculoskeletal disease entities. This review analyzes published studies on this subject and summarizes current information on altered sensory and pain perception available for some of the most common musculoskeletal disorders. At present, QST remains primarily a research tool but may be useful in differential diagnosis in indicating the presence of central sensitization and for clinical monitoring of disease progression or treatment response."],["dc.identifier.doi","10.1007/s11926-010-0131-0"],["dc.identifier.fs","577728"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6827"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60332"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Current Science Inc."],["dc.publisher.place","New York"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","The Role of Quantitative Sensory Testing in the Evaluation of Musculoskeletal Pain Conditions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Neurology International"],["dc.bibliographiccitation.volume","13"],["dc.contributor.affiliation","Dibaj, Payam; \t\t \r\n\t\t Center for Rare Diseases Göttingen (ZSEG), University Medical Center Göttingen, Georg August University, 37075 Göttingen, Germany, payam.dibaj@med.uni-goettingen.de\t\t \r\n\t\t Department of Neurogenetics, Max-Planck-Institute for Experimental Medicine, 37075 Göttingen, Germany, payam.dibaj@med.uni-goettingen.de\t\t \r\n\t\t Center for Neurology, Asklepios Hospitals Schildautal, 38723 Seesen, Germany, payam.dibaj@med.uni-goettingen.de"],["dc.contributor.affiliation","Seeger, Dagmar; \t\t \r\n\t\t Pain Clinic, Center for Anesthesiology, University Medical Center Göttingen, Georg August University, 37075 Göttingen, Germany, dseeger@med.uni-goettingen.de"],["dc.contributor.affiliation","Gärtner, Jutta; \t\t \r\n\t\t Center for Rare Diseases Göttingen (ZSEG), University Medical Center Göttingen, Georg August University, 37075 Göttingen, Germany, gaertnj@med.uni-goettingen.de\t\t \r\n\t\t Department of Pediatrics and Pediatric Neurology, University Medical Center Göttingen, Georg August University, 37075 Göttingen, Germany, gaertnj@med.uni-goettingen.de"],["dc.contributor.affiliation","Petzke, Frank; \t\t \r\n\t\t Pain Clinic, Center for Anesthesiology, University Medical Center Göttingen, Georg August University, 37075 Göttingen, Germany, frank.petzke@med.uni-goettingen.de"],["dc.contributor.author","Dibaj, Payam"],["dc.contributor.author","Seeger, Dagmar"],["dc.contributor.author","Gärtner, Jutta"],["dc.contributor.author","Petzke, Frank"],["dc.date.accessioned","2022-04-05T11:39:45Z"],["dc.date.available","2022-04-05T11:39:45Z"],["dc.date.issued","2021-02-25"],["dc.date.updated","2022-09-06T03:56:43Z"],["dc.description.abstract","A 60-year-old man suffering from recurrent attacks of yawning-fatigue-syndrome, triggered by mild exercise of his right leg since a temporary lumbar disc herniation 9 years ago, was initially treated with the oral µ-opioid-receptor agonist tilidine before each bout of exercise (see Dibaj et al. 2019 JAMA Neurology 2019;77:254). During the first few months, this treatment continuously prolonged the time without exercise-triggered yawning and fatigue. In the next few months of treatment, exercise was increased in a graded manner to alleviate the yawning-fatigue-syndrome. The number of repetitions of the physical exercises was gradually increased without taking the opioid beforehand. After several months, almost the same effort level without medication could be achieved by graded activity as before under the influence of opioid medication. Graded physical activity can thus disrupt complex pathophysiological mechanisms leading to yawning and fatigue."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.doi","10.3390/neurolint13010008"],["dc.identifier.pmid","33668800"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/106399"],["dc.language.iso","en"],["dc.relation.eissn","2035-8377"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.relation.orgunit","Max-Planck-Institut für Experimentelle Medizin"],["dc.relation.orgunit","Klinik für Anästhesiologie"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Follow-Up of a Case of Dopamine-Mediated Yawning-Fatigue-Syndrome Responsive to Opioids, Successful Desensitization via Graded Activity Treatment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","908133"],["dc.bibliographiccitation.journal","Frontiers in Medicine"],["dc.bibliographiccitation.volume","9"],["dc.contributor.affiliation","Ramasawmy, Perianen; 1Department of Neurology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany"],["dc.contributor.affiliation","Khalid, Sarah; 1Department of Neurology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany"],["dc.contributor.affiliation","Petzke, Frank; 2Department of Anesthesiology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany"],["dc.contributor.affiliation","Antal, Andrea; 1Department of Neurology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany"],["dc.contributor.author","Ramasawmy, Perianen"],["dc.contributor.author","Khalid, Sarah"],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Antal, Andrea"],["dc.date.accessioned","2022-12-01T08:31:31Z"],["dc.date.available","2022-12-01T08:31:31Z"],["dc.date.issued","2022"],["dc.date.updated","2022-11-11T13:12:39Z"],["dc.description.abstract","Background\r\n This double-blinded, randomized and sham-controlled pilot clinical trial aimed to investigate the preliminary clinical efficacy and feasibility of combining mindfulness meditation (MM) and transcranial direct current stimulation (tDCS) for pain and associated symptoms in patients with fibromyalgia syndrome (FMS).\r\n \r\n \r\n Methods\r\n \r\n Included FMS patients (age: 33 to 70) were randomized to three different groups to receive either ten daily sessions of anodal tDCS over the left primary motor cortex paired with MM for 20 min (active + MM, n = 10), sham tDCS combined with MM (sham + MM,\r\n n\r\n = 10) or no intervention (NoT,\r\n n\r\n = 10). Patients in the bimodal therapy groups received a week of training in MM prior to the stimulation. Participants reported pain intensity, the primary outcome, by filling in a pain diary daily throughout the whole study. They were also evaluated for quality of life, pressure pain sensitivity, psychological wellbeing, sleep quality and sleep quantity. Assessments were performed at three time points (baseline, immediately after treatment and one-month follow-up).\r\n \r\n \r\n \r\n Results\r\n Participants in the active + MM group did not exhibit reduced pain intensity following the bimodal therapy compared to controls. Patients in active group demonstrated clinically meaningful and significantly higher quality of life following the therapeutic intervention than other groups. There was no significant difference among groups regarding pressure pain sensitivity, sleep parameters and psychological scales. The combined treatment was well tolerated among participants, with no serious adverse effects.\r\n \r\n \r\n Conclusion\r\n This study was the first to pair these two effective non-pharmacological therapies for pain management in FMS. In the light of an underpowered sample size, repetitive anodal tDCS combined with MM did not improve pain or FMS-associated symptoms. However, patients in the active + MM group reported higher quality of life than the control groups. Studies with more participants and longer follow-ups are required to confirm our findings.\r\n \r\n \r\n Clinical trial registration\r\n \r\n [\r\n www.drks.de\r\n ], identifier [DRKS00023490]."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3389/fmed.2022.908133"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118192"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-621"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","2296-858X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Pain reduction in fibromyalgia syndrome through pairing transcranial direct current stimulation and mindfulness meditation: A randomized, double-blinded, sham-controlled pilot clinical trial"],["dc.title.subtitle","A randomized, double-blinded, sham-controlled pilot clinical trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]