Petzke, Frank

[["dc.bibliographiccitation.artnumber","e0182207"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Schäfer, Axel Georg Meender"],["dc.contributor.author","Joos, Leonie Johanna"],["dc.contributor.author","Roggemann, Katharina"],["dc.contributor.author","Waldvogel-Röcker, Kerstin"],["dc.contributor.author","Pfingsten, Michael"],["dc.contributor.author","Petzke, Frank"],["dc.date.accessioned","2019-07-09T11:44:35Z"],["dc.date.available","2019-07-09T11:44:35Z"],["dc.date.issued","2017"],["dc.description.abstract","OBJECTIVES: Central sensitization (CS) is regarded as an important contributing factor for chronification of musculoskeletal pain (MSP). It is crucial to identify CS, as targeted multimodal treatment may be indicated. The primary objective of this study was therefore to explore pain experience of individuals with MSP+CS in order to gain a better understanding of symptoms in relation to CS from a patient perspective. The secondary objective was to investigate whether pain experiences of patients with MSP+CS differ from those of individuals with neuropathic pain (NP). METHODS: We conducted a comparative Group Delphi Study including patients with MSP+CS and neuropathic pain (NP). 13 guiding questions were used to gather information about sensory discriminatory, affective and associated bodily, mental and emotional phenomena related to the pain experience of patients. Descriptions were categorized using qualitative content analysis. Additionally, patients completed several pain related questionnaires. RESULTS: Nine participants with MSP+CS and nine participants with NP participated. The Delphi procedure revealed three main themes: psycho-emotional factors, bodily factors and environmental factors. Descriptions of patients with MSP+CS showed a complex picture, psycho-emotional factors seem to have a considerable impact on pain provocation, aggravation and relief. Impairments associated with mental ability and psyche affected many aspects of daily life. In contrast, descriptions of patients with NP revealed a rather mechanistic and bodily oriented pain experience. DISCUSSION: Patients with MSP+CS reported distinct features in relation to their pain that were not captured with current questionnaires. Insight in patient's pain experience may help to choose and develop appropriate diagnostic instruments."],["dc.description.abstract","OBJECTIVES: Central sensitization (CS) is regarded as an important contributing factor for chronification of musculoskeletal pain (MSP). It is crucial to identify CS, as targeted multimodal treatment may be indicated. The primary objective of this study was therefore to explore pain experience of individuals with MSP+CS in order to gain a better understanding of symptoms in relation to CS from a patient perspective. The secondary objective was to investigate whether pain experiences of patients with MSP+CS differ from those of individuals with neuropathic pain (NP). METHODS: We conducted a comparative Group Delphi Study including patients with MSP+CS and neuropathic pain (NP). 13 guiding questions were used to gather information about sensory discriminatory, affective and associated bodily, mental and emotional phenomena related to the pain experience of patients. Descriptions were categorized using qualitative content analysis. Additionally, patients completed several pain related questionnaires. RESULTS: Nine participants with MSP+CS and nine participants with NP participated. The Delphi procedure revealed three main themes: psycho-emotional factors, bodily factors and environmental factors. Descriptions of patients with MSP+CS showed a complex picture, psycho-emotional factors seem to have a considerable impact on pain provocation, aggravation and relief. Impairments associated with mental ability and psyche affected many aspects of daily life. In contrast, descriptions of patients with NP revealed a rather mechanistic and bodily oriented pain experience. DISCUSSION: Patients with MSP+CS reported distinct features in relation to their pain that were not captured with current questionnaires. Insight in patient's pain experience may help to choose and develop appropriate diagnostic instruments."],["dc.identifier.doi","10.1371/journal.pone.0182207"],["dc.identifier.pmid","28796805"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14821"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59039"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.subject.mesh","Adult"],["dc.subject.mesh","Aged"],["dc.subject.mesh","Central Nervous System Sensitization"],["dc.subject.mesh","Chronic Pain"],["dc.subject.mesh","Cross-Sectional Studies"],["dc.subject.mesh","Delphi Technique"],["dc.subject.mesh","Emotions"],["dc.subject.mesh","Female"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Male"],["dc.subject.mesh","Middle Aged"],["dc.subject.mesh","Musculoskeletal Pain"],["dc.subject.mesh","Neuralgia"],["dc.subject.mesh","Pain Measurement"],["dc.subject.mesh","Qualitative Research"],["dc.subject.mesh","Quality of Life"],["dc.title","Pain experiences of patients with musculoskeletal pain + central sensitization: A comparative Group Delphi Study."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0186400"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Gram, Mikkel"],["dc.contributor.author","Erlenwein, Joachim"],["dc.contributor.author","Petzke, Frank"],["dc.contributor.author","Falla, Deborah"],["dc.contributor.author","Przemeck, Michael"],["dc.contributor.author","Emons, Miriam I."],["dc.contributor.author","Reuster, Michael"],["dc.contributor.author","Olesen, Søren S."],["dc.contributor.author","Drewes, Asbjørn M."],["dc.date.accessioned","2019-07-09T11:44:41Z"],["dc.date.available","2019-07-09T11:44:41Z"],["dc.date.issued","2017"],["dc.description.abstract","BACKGROUND: Experimental models have been used extensively to evaluate pain using e.g., visual analogue scales or electroencephalography (EEG). Stimulation using tonic pain has been shown to better mimic the unpleasantness of chronic pain, but has mainly been evoked by non-clinical stimuli. This study aims to, evaluate the EEG during clinical pain in patients scheduled for total hip replacement with control and resting conditions. METHODS: The hip scheduled for replacement was moved by the examiner to evoke pain for 30 seconds while recording EEG. The control condition entailed movement of the opposite hip in a similar fashion and holding it for 30 seconds. In addition, EEG was recorded during the resting condition with open eyes. The relative spectral content was calculated from the EEG as well as functional connectivity using phase-lag index for frequency bands delta (1-4Hz), theta (4-8Hz), alpha (8-12Hz) and beta (12-32Hz). A mixed model was used for statistical comparison between the three recording conditions. RESULTS: Spectral content differed between conditions in all bands. Functional connectivity differed in delta and theta frequency bands. Post-hoc analysis revealed differences between the painful and control condition in delta, theta and beta for spectral content. Pain during the hip rotation was correlated to the theta (r = -0.24 P = 0.03) and beta (r = 0.25 P = 0.02) content in the EEG. CONCLUSION: EEG differences during hip movements in the affected and unaffected hip appeared in the spectral beta and theta content. This was correlated to the reported pain perceived, pointing towards pain specific brain activity related to clinical pain."],["dc.identifier.doi","10.1371/journal.pone.0186400"],["dc.identifier.pmid","29084278"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14866"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59066"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.subject.mesh","Animals"],["dc.subject.mesh","Cats"],["dc.subject.mesh","Cerebral Cortex"],["dc.subject.mesh","Electroencephalography"],["dc.subject.mesh","Female"],["dc.subject.mesh","Guinea Pigs"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Male"],["dc.subject.mesh","Osteoarthritis, Hip"],["dc.subject.mesh","Pain"],["dc.title","The cortical responses to evoked clinical pain in patients with hip osteoarthritis."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]