Köhler, Michael

[["dc.bibliographiccitation.journal","European Radiology"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Bachanek, Sophie"],["dc.contributor.author","Onur, Mehmet Ruhi"],["dc.contributor.author","Kinner, Sonja"],["dc.contributor.author","Geisel, Dominik"],["dc.contributor.author","Köhler, Michael"],["dc.contributor.author","Preibsch, Heike"],["dc.contributor.author","Puesken, Michael"],["dc.contributor.author","Surov, Alexey"],["dc.date.accessioned","2021-08-12T07:45:57Z"],["dc.date.available","2021-08-12T07:45:57Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract Objectives To assess imaging features of primary renal sarcomas in order to better discriminate them from non-sarcoma renal tumors. Methods Adult patients diagnosed with renal sarcomas from 1995 to 2018 were included from 11 European tertiary referral centers (Germany, Belgium, Turkey). Renal sarcomas were 1:4 compared to patients with non-sarcoma renal tumors. CT/MRI findings were assessed using 21 predefined imaging features. A random forest model was trained to predict “renal sarcoma vs. non-sarcoma renal tumors” based on demographics and imaging features. Results n = 34 renal sarcomas were included and compared to n = 136 non-sarcoma renal tumors. Renal sarcomas manifested in younger patients (median 55 vs. 67 years, p < 0.01) and were more complex (high RENAL score complexity 79.4% vs. 25.7%, p < 0.01). Renal sarcomas were larger (median diameter 108 vs. 43 mm, p < 0.01) with irregular shape and ill-defined margins, and more frequently demonstrated invasion of the renal vein or inferior vena cava, tumor necrosis, direct invasion of adjacent organs, and contact to renal artery or vein, compared to non-sarcoma renal tumors ( p < 0.05, each). The random forest algorithm yielded a median AUC = 93.8% to predict renal sarcoma histology, with sensitivity, specificity, and positive predictive value of 90.4%, 76.5%, and 93.9%, respectively. Tumor diameter and RENAL score were the most relevant imaging features for renal sarcoma identification. Conclusion Renal sarcomas are rare tumors commonly manifesting as large masses in young patients. A random forest model using demographics and imaging features shows good diagnostic accuracy for discrimination of renal sarcomas from non-sarcoma renal tumors, which might aid in clinical decision-making. Key Points • Renal sarcomas commonly manifest in younger patients as large, complex renal masses. • Compared to non-sarcoma renal tumors, renal sarcomas more frequently demonstrated invasion of the renal vein or inferior vena cava, tumor necrosis, direct invasion of adjacent organs, and contact to renal artery or vein. • Using demographics and standardized imaging features, a random forest showed excellent diagnostic performance for discrimination of sarcoma vs. non-sarcoma renal tumors (AUC = 93.8%, sensitivity = 90.4%, specificity = 76.5%, and PPV = 93.9%)."],["dc.description.abstract","Abstract Objectives To assess imaging features of primary renal sarcomas in order to better discriminate them from non-sarcoma renal tumors. Methods Adult patients diagnosed with renal sarcomas from 1995 to 2018 were included from 11 European tertiary referral centers (Germany, Belgium, Turkey). Renal sarcomas were 1:4 compared to patients with non-sarcoma renal tumors. CT/MRI findings were assessed using 21 predefined imaging features. A random forest model was trained to predict “renal sarcoma vs. non-sarcoma renal tumors” based on demographics and imaging features. Results n = 34 renal sarcomas were included and compared to n = 136 non-sarcoma renal tumors. Renal sarcomas manifested in younger patients (median 55 vs. 67 years, p < 0.01) and were more complex (high RENAL score complexity 79.4% vs. 25.7%, p < 0.01). Renal sarcomas were larger (median diameter 108 vs. 43 mm, p < 0.01) with irregular shape and ill-defined margins, and more frequently demonstrated invasion of the renal vein or inferior vena cava, tumor necrosis, direct invasion of adjacent organs, and contact to renal artery or vein, compared to non-sarcoma renal tumors ( p < 0.05, each). The random forest algorithm yielded a median AUC = 93.8% to predict renal sarcoma histology, with sensitivity, specificity, and positive predictive value of 90.4%, 76.5%, and 93.9%, respectively. Tumor diameter and RENAL score were the most relevant imaging features for renal sarcoma identification. Conclusion Renal sarcomas are rare tumors commonly manifesting as large masses in young patients. A random forest model using demographics and imaging features shows good diagnostic accuracy for discrimination of renal sarcomas from non-sarcoma renal tumors, which might aid in clinical decision-making. Key Points • Renal sarcomas commonly manifest in younger patients as large, complex renal masses. • Compared to non-sarcoma renal tumors, renal sarcomas more frequently demonstrated invasion of the renal vein or inferior vena cava, tumor necrosis, direct invasion of adjacent organs, and contact to renal artery or vein. • Using demographics and standardized imaging features, a random forest showed excellent diagnostic performance for discrimination of sarcoma vs. non-sarcoma renal tumors (AUC = 93.8%, sensitivity = 90.4%, specificity = 76.5%, and PPV = 93.9%)."],["dc.identifier.doi","10.1007/s00330-021-08201-4"],["dc.identifier.pii","8201"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88583"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation.eissn","1432-1084"],["dc.relation.issn","0938-7994"],["dc.title","Primary renal sarcomas: imaging features and discrimination from non-sarcoma renal tumors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.lastpage","6"],["dc.bibliographiccitation.volume","100"],["dc.contributor.author","Wildgruber, Moritz"],["dc.contributor.author","Köhler, Michael"],["dc.contributor.author","Brill, Richard"],["dc.contributor.author","Goessmann, Holger"],["dc.contributor.author","Uller, Wibke"],["dc.contributor.author","Müller-Wille, René"],["dc.contributor.author","Wohlgemuth, Walter A."],["dc.date.accessioned","2020-12-10T14:23:43Z"],["dc.date.available","2020-12-10T14:23:43Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.ejrad.2018.01.011"],["dc.identifier.issn","0720-048X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72021"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Impact of low dose settings on radiation exposure during pediatric fluoroscopic guided interventions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Dental Research"],["dc.bibliographiccitation.volume","79"],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Jager, G. C."],["dc.contributor.author","Hornecker, Else"],["dc.contributor.author","Wieding, J. U."],["dc.contributor.author","Kohler, M."],["dc.date.accessioned","2018-11-07T11:08:37Z"],["dc.date.available","2018-11-07T11:08:37Z"],["dc.date.issued","2000"],["dc.format.extent","315"],["dc.identifier.isi","000084937001367"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52825"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Dental Research"],["dc.publisher.place","Alexandria"],["dc.relation.issn","0022-0345"],["dc.title","Periodontal status and laboratory blood analysis of blood-donors."],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","109"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Annals of Hematology"],["dc.bibliographiccitation.lastpage","112"],["dc.bibliographiccitation.volume","80"],["dc.contributor.author","Humpe, Andreas"],["dc.contributor.author","Riggert, Joachim"],["dc.contributor.author","Wolf, C."],["dc.contributor.author","Binder, Claudia"],["dc.contributor.author","Kohler, M."],["dc.date.accessioned","2018-11-07T09:23:01Z"],["dc.date.available","2018-11-07T09:23:01Z"],["dc.date.issued","2001"],["dc.description.abstract","Transplantation of peripheral blood stem cells (PBSC), positively and/or negatively selected immediately after harvest, has become a widely applied therapeutic option in hematological or oncological patients. The following case of peripheral blood stem cell transplantation represents the first case of successful transplantation of PBSC, cryopreserved twice and purged after cryopreservation. PBSC were harvested in a 44-year-old female patient with a low-grade non-Hodgkin's lymphoma stage IV after mobilization with chemotherapy and G-CSF. A total number of 15.2 x 10(6) CD34(+) cells/kg bodyweight was harvested with a 36.9% contamination of tumor cells coexpressing CD5 and CD20. After subsequent chemotherapy cycles and cyclophosphamide mobilization, only 0.77 x 10(6) CD34(+) cells/kg bodyweight, not sufficient for transplantation, were achieved after positive selection. Therefore, 10.8 x 10(6) cryopreserved CD34(+) cells/kg bodyweight were thawed and a positive selection was carried out with the BAXTER Isolex 300i machine. Before additional negative selection, the 0.77 x 10(6) positively selected CD34(+) cells/kg bodyweight from the second mobilization were added. A total quantity of 4.4 x 10(6) CD34(+) cells/kg bodyweight with a purity of 93.1% representing a recovery of 38% was obtained. Cells were again cryopreserved, stored and retransfused after conditioning the patient with TBI and high-dose cyclophosphamide. The patient engrafted with a WBC count >1000/mul on day eight and a platelet count > 20,000/mul without transfusion support on day 12 post-transplantation. This case indicates that purging procedures can successfully be carried out with cryopreserved cell material and that purified CD34(+) cells can be cryopreserved a second time before transplantation, without affecting their hematopoietic capacity."],["dc.identifier.doi","10.1007/s002770000243"],["dc.identifier.isi","000167191200010"],["dc.identifier.pmid","11261320"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29482"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0939-5555"],["dc.title","Successful transplantation and engraftment of peripheral blood stem cells after cryopreservation, positive and negative purging procedures, and a second cryopreservation cycle"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","109"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Clinical Apheresis"],["dc.bibliographiccitation.lastpage","113"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Humpe, Andreas"],["dc.contributor.author","Riggert, Joachim"],["dc.contributor.author","Koch, S."],["dc.contributor.author","Legler, Tobias Joerg"],["dc.contributor.author","Munzel, U."],["dc.contributor.author","Kohler, M."],["dc.date.accessioned","2018-11-07T09:34:58Z"],["dc.date.available","2018-11-07T09:34:58Z"],["dc.date.issued","2001"],["dc.description.abstract","Some data exist on the influence of leukapheresis volume on the number of harvested peripheral blood hematopoietic progenitor cells (HPC), but less is known about the influence on the composition of HPC. We therefore performed a prospective, randomized crossover trial to evaluate the effect of large-volume (LVL) vs. normal-volume leukapheresis (NVL) on subpopulations of CD34(+) cells in the harvest product of 15 patients with breast cancer and 8 patients with non-Hodgkin's lymphoma. Patients were randomly assigned to start either with an LVL on day 1 followed by an NVL on day 2 or vice versa. The number of HPC; the extraction efficiency defined as difference between yield in the harvest and decrease in peripheral blood, and the relative proportion as well as the absolute numbers of CD34(+) cells coexpressing CD38, CD90, HLA-DR, CD117, CD7, CD19, CD41, or CD33 were evaluated. There was no significant difference with regard to the percentages of the subsets on comparison of LVL to NVL procedures. Only the absolute median number of CD34(+)HLA-DR- cells was significantly (P=0.02) higher in LVL harvests compared with the corresponding NVL components; which can be explained on the basis of the higher yield and the higher extraction efficiency in LVL compared with NVL. LVL results in a higher yield of CD34(+) cells and leads to an intra-apheresis recruitment of HPC but the relative composition of the harvested CD34(+) cells is not changed significantly. In addition, the amount of early, HLA-DR-, hematopoietic HPC seems to be increased by an LVL. (C) 2001 Wiley-Liss, Inc."],["dc.identifier.isi","000171650400001"],["dc.identifier.pmid","11746535"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32289"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-liss"],["dc.relation.issn","0733-2459"],["dc.title","Prospective, randomized, sequential, crossover trial of large-volume vs. normal-volume leukapheresis procedures: Effects on subpopulations of CD34(+) cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","327"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Plant and Soil"],["dc.bibliographiccitation.lastpage","335"],["dc.bibliographiccitation.volume","376"],["dc.contributor.author","Meißner, Meik"],["dc.contributor.author","Köhler, Michael"],["dc.contributor.author","Schwendenmann, Luitgard"],["dc.contributor.author","Hölscher, Dirk"],["dc.contributor.author","Dyckmans, Jens"],["dc.date.accessioned","2017-09-07T11:45:37Z"],["dc.date.available","2017-09-07T11:45:37Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1007/s11104-013-1970-z"],["dc.identifier.gro","3149058"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/5702"],["dc.notes.intern","Hoelscher Crossref import"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.publisher","Springer Nature"],["dc.relation.issn","0032-079X"],["dc.title","Soil water uptake by trees using water stable isotopes (δ2H and δ18O)−a method test regarding soil moisture, texture and carbonate"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","612"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Transfusion"],["dc.bibliographiccitation.lastpage","618"],["dc.bibliographiccitation.volume","42"],["dc.contributor.author","Lynen, R."],["dc.contributor.author","Krone, O."],["dc.contributor.author","Legler, Tobias Joerg"],["dc.contributor.author","Kohler, M."],["dc.contributor.author","Mayr, Wolfgang R."],["dc.date.accessioned","2018-11-07T10:30:29Z"],["dc.date.available","2018-11-07T10:30:29Z"],["dc.date.issued","2002"],["dc.description.abstract","BACKGROUND: Novel gel centrifugation test (GCT) cards were evaluated with respect to their ability to estimate the quantity of IgG on RBCs and the determination of the IgG subclasses IgG1 and IgG3. STUDY DESIGN AND METHODS: In 65 patients with a positive DAT, the amount of IgG-gamma-, IgG1, and IgG3 on RBCs was examined by use of GCT cards and flow cytometry (FC) in parallel. The results were correlated with the presence or absence of hemolysis. In addition, D+ RBCs were studied after sensitization with anti-D sera from 22 alloimmunized pregnant women. RESULTS: The amount of IgG on the RBCs as determined by GCT dilution cards correlated with FC (r = 0.70, p < 0.0001). IgG subclass results as determined by GCT IgG subclass cards were confirmed by FC in 14 cases with an anti-IgG-gamma-chain titer greater than or equal to300, whereas IgG subclass cards were not suitable in cases with anti-IgG-gamma-chain titers less than 300. In 44 patients with 2+ or 3+ DAT in the GCT and anti-IgG-gamma-chain titer less than or equal to30, no hemolysis was observed, whereas hemolysis occurred in 13 of 14 patients with an anti-IgG-gamma-chain titer greater than or equal to300. GCT data obtained by IATs with anti-D sera were concordant with FC results. CONCLUSION: There is a correlation between the amount of RBC-bound IgG and immune hemolysis. The GCT cards that detect the anti-IgG-gamma-chain may be useful to predict hemolysis in patients with a 2+ or 3+ DAT in the GCT. The diagnostic value of GCT cards for IgG subclass testing should be investigated further."],["dc.identifier.doi","10.1046/j.1537-2995.2002.00076.x"],["dc.identifier.isi","000176104300014"],["dc.identifier.pmid","12084170"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43882"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Blood Banks"],["dc.relation.issn","0041-1132"],["dc.title","A newly developed gel centrifugation test for quantification of RBC-bound IgG antibodies and their subclasses IgG1 and IgG3: comparison with flow cytometry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","520"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Ecohydrology"],["dc.bibliographiccitation.lastpage","529"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Köhler, Michael"],["dc.contributor.author","Dierick, Diego"],["dc.contributor.author","Schwendenmann, Luitgard"],["dc.contributor.author","Hölscher, Dirk"],["dc.date.accessioned","2017-09-07T11:45:48Z"],["dc.date.available","2017-09-07T11:45:48Z"],["dc.date.issued","2009"],["dc.description.abstract","Water use characteristics of cacao (Theobroma cacao) and Gliricidia sepium shade trees were studied in an agroforest on Sulawesi, Indonesia. The objectives were: (1) to identify environmental and tree structural factors controlling water use, (2) to analyse the effect of shade tree cover on cacao water use and (3) to estimate stand level transpiration. Sap flux density was measured in up to 18 trees per species and described with a Jarvis-type model. Model parameters suggested a 49% higher maximum sap flux density in cacao than in Gliricidia and species differences in the response to vapour pressure deficit and radiation. Tree water use was positively related to tree diameter in both species, but this relationship tended to differ between species. In cacao trees maximal tree water use increased with decreasing canopy gap fraction above the trees (R2adj = 0·39, p = 0·04). This was paralleled by an increase of cacao stem diameter and leaf area with decreasing gap fraction. Maximum water use rate per unit crown area of cacao was 13% higher than that of Gliricidia. At the stand level the average transpiration rate was estimated at 1·5 mm day−1 per unit ground area, 70% of which was contributed to by cacao. We conclude that, in the given stand, species differed substantially in water use characteristics, while estimated stand transpiration is in line with findings from other studies for cacao stands. Shade trees may enhance stand transpiration through own water use and additionally by increasing water use rates of cacao trees"],["dc.identifier.doi","10.1002/eco.67"],["dc.identifier.gro","3149111"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/5760"],["dc.language.iso","en"],["dc.notes.intern","Hoelscher Crossref import"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.relation.issn","1936-0584"],["dc.title","Water use characteristics of cacao and Gliricidiatrees in an agroforest in Central Sulawesi, Indonesia"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","830"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Transfusion"],["dc.bibliographiccitation.lastpage","831"],["dc.bibliographiccitation.volume","43"],["dc.contributor.author","Koehler, M."],["dc.contributor.author","Riggert, Joachim"],["dc.contributor.author","Legler, Tobias Joerg"],["dc.contributor.author","Mayr, Wolfgang R."],["dc.contributor.author","Schwartz, DWM"],["dc.contributor.author","Heermann, K. H."],["dc.date.accessioned","2018-11-07T10:38:50Z"],["dc.date.available","2018-11-07T10:38:50Z"],["dc.date.issued","2003"],["dc.identifier.doi","10.1046/j.1537-2995.2003.00409.x"],["dc.identifier.isi","000183119000025"],["dc.identifier.pmid","12757539"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45903"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Blood Banks"],["dc.relation.issn","0041-1132"],["dc.title","Risk of transfusion-transmitted infections by NAT-negative blood"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1363"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Transfusion"],["dc.bibliographiccitation.lastpage","1370"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Humpe, Andreas"],["dc.contributor.author","Riggert, Joachim"],["dc.contributor.author","Meineke, Ingolf"],["dc.contributor.author","Kurz, M."],["dc.contributor.author","Eil, A."],["dc.contributor.author","Storkebaum, B."],["dc.contributor.author","Binder, Claudia"],["dc.contributor.author","Munzel, U."],["dc.contributor.author","Funke, I."],["dc.contributor.author","Hocker, P."],["dc.contributor.author","Wiesneth, M."],["dc.contributor.author","Kohler, M."],["dc.date.accessioned","2018-11-07T08:55:02Z"],["dc.date.available","2018-11-07T08:55:02Z"],["dc.date.issued","2000"],["dc.description.abstract","BACKGROUND: Mobilization and homing of PBPCs are still poorly understood. Thus, a sufficient algorithm for the prediction of PBPC yield in apheresis procedures does not yet exist. STUDY DESIGN AND METHODS: The decline of CD34+ cells in the peripheral blood during apheresis and their simultaneous increase in the collection bag were determined in a prospective study of 18 consecutive apheresis procedures. A cell-kinetic, four-compartment model describing these changes was developed. Retrospective data from 136 apheresis procedures served to further improve this model. A predictive algorithm for the yield was developed that considered the sex, weight, and height of the patient, the number of CD34+ cells in peripheral blood before apheresis, the inlet flow, and the duration of the apheresis. The accuracy of this algorithm was evaluated by comparison of the predicted and the observed yields of CD34+ cells in 105 prospective autologous and 148 retrospective allogeneic apheresis procedures. RESULTS: The correlation between predicted and observed yields was good for the autologous and allogeneic groups with a correlation coefficient (r) of 0.8979 and 0.8311 (p<0.0001), respectively. The regression is described by the equations log (measured value [m]) = 1.0118 + 0.8595 x log (predicted value [p]) for the autologous and log (m) = 2.226 + 0.7559 x log (p) for the allogeneic group. The respective equations for the zero-point regression are log (m)= 1.014 x log (p) and log (m) = 1.026 x log (p). The probability that the measured value was 90 percent or more of the predicted value was 83.8 percent for the autologous and 90.5 percent for the allogeneic apheresis procedures. CONCLUSION: The predictive accuracy of the algorithm and the slope of the zero-point regression curve were higher for allogeneic than autologous PBPC collections. The predictive algorithm may be a useful tool in PBPC harvest, enabling the adaptation of the size of the apheresis to the needs of each patient."],["dc.identifier.doi","10.1046/j.1537-2995.2000.40111363.x"],["dc.identifier.isi","000165492600013"],["dc.identifier.pmid","11099666"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22808"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Blood Banks"],["dc.relation.issn","0041-1132"],["dc.title","A cell-kinetic model of CD34+cell mobilization and harvest: development of a predictive algorithm for CD34+cell yield in PBPC collections"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]