Trojan, Lutz

[["dc.bibliographiccitation.firstpage","3010"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Cancers"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Leha, Andreas"],["dc.contributor.author","Delonge, Laura M."],["dc.contributor.author","Haack, Anna-Maria"],["dc.contributor.author","Shuch, Brian"],["dc.contributor.author","Kim, Hyun S."],["dc.contributor.author","Bremmer, Felix"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Uhlig, Annemarie"],["dc.date.accessioned","2021-04-14T08:31:08Z"],["dc.date.available","2021-04-14T08:31:08Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.3390/cancers12103010"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17620"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83497"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","MDPI"],["dc.relation.eissn","2072-6694"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Radiomic Features and Machine Learning for the Discrimination of Renal Tumor Histological Subtypes: A Pragmatic Study Using Clinical-Routine Computed Tomography"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","122"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","The Open Public Health Journal"],["dc.bibliographiccitation.lastpage","133"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Strauss, Arne"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.date.accessioned","2019-07-09T11:45:23Z"],["dc.date.available","2019-07-09T11:45:23Z"],["dc.date.issued","2018"],["dc.description.abstract","Purpose: To summarize the current evidence on preventive services utilization in cancer survivors. Methods: A systematic literature review and meta-analysis was conducted in February 2016. Studies were included if they compared the utilization of influenza vaccination, cholesterol/lipid testing, bone densitometry, or blood pressure measurement among survivors of adulthood cancer to cancer-free controls. Random effects meta-analyses were conducted to pool estimates. Results: Literature search identified 3740 studies of which 10 fulfilled the inclusion criteria. Cancer survivors were significantly more likely to utilize bone densitometry (OR=1.226, 95% CI: 1.114 – 1.350, p<0.001) and influenza vaccination (OR=1.565, 95% CI: 1.176 – 2.082, p=0.002) than cancer-free controls. No statistically significant differences were detected for blood pressure measurement and cholesterol/lipid testing (OR=1.322, 95% CI: 0.812 – 2.151, p=0.261; OR=1.046, 95% CI: 0.96 – 1.139, p=0.304). Conclusions: Cancer survivors were more likely to receive influenza vaccinations and bone densitometry. Future studies should evaluate underlying mechanisms and whether the utilization of preventive services translates into prolonged survival of cancer survivors. Implications for Cancer Survivors: Our meta-analysis demonstrated cancer survivors to be more likely to receive the preventive services such as influenza vaccination and bone densitometry than cancer free controls. Still, these results should be interpreted in the context of suboptimal utilization of preventive services in general, and for cancer survivors in specific. Future research should evaluate the underlying mechanisms and whether utilization of preventive services is associated with overall survival in cancer survivors."],["dc.identifier.doi","10.2174/1874944501811010122"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15190"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59219"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1874-9445"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","Preventive Services Utilization Among Cancer Survivors Compared to Cancer-free Controls"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","64"],["dc.bibliographiccitation.journal","Urology Case Reports"],["dc.bibliographiccitation.lastpage","66"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Behnes, Carl Ludwig"],["dc.contributor.author","Strauss, Arne"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Leitsmann, Conrad"],["dc.date.accessioned","2019-07-09T11:45:15Z"],["dc.date.available","2019-07-09T11:45:15Z"],["dc.date.issued","2018"],["dc.description.abstract","Primary Bladder Adenocarcinoma is a rare malignancy that has been observed in a heterogeneous pa- tient population. This case report presents a 51 year old female with muscle-invasive primary bladder adenocarcinoma diagnosed in 2008. After transurethral resection and cystectomy with ileum neobladder adjuvant radi- ochemotherapy was administered. Two years later, a symptomatic fistula between neobladder and ileoileal anastomosis was excised, resulting in urinary incontinency. In 2016, the patient shows no signs of disease relapse but suffers from reduction of bladder capacity. This case report presents classical symptoms of adenocarcinoma of the bladder and a possible treat- ment regimen with associated side effects."],["dc.identifier.doi","10.1016/j.eucr.2018.02.006"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15073"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59191"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","2214-4420"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.subject.ddc","610"],["dc.title","Primary bladder adenocarcinoma: Case report with long-term follow-up"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Surgery"],["dc.bibliographiccitation.volume","9"],["dc.contributor.affiliation","Reichert, Mathias; 1Department of Urology, University Medical Center Goettingen, Goettingen, Germany"],["dc.contributor.affiliation","Ploeger, Hannah Maria; 2Department of Pediatrics, University Hospital Bonn, Bonn, Germany"],["dc.contributor.affiliation","Uhlig, Annemarie; 1Department of Urology, University Medical Center Goettingen, Goettingen, Germany"],["dc.contributor.affiliation","Strauss, Arne; 1Department of Urology, University Medical Center Goettingen, Goettingen, Germany"],["dc.contributor.affiliation","Henniges, Philipp; 1Department of Urology, University Medical Center Goettingen, Goettingen, Germany"],["dc.contributor.affiliation","Trojan, Lutz; 1Department of Urology, University Medical Center Goettingen, Goettingen, Germany"],["dc.contributor.affiliation","Mohr, Mirjam Naomi; 1Department of Urology, University Medical Center Goettingen, Goettingen, Germany"],["dc.contributor.author","Reichert, Mathias"],["dc.contributor.author","Ploeger, Hannah Maria"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Strauss, Arne"],["dc.contributor.author","Henniges, Philipp"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Mohr, Mirjam Naomi"],["dc.date.accessioned","2022-12-07T08:25:13Z"],["dc.date.available","2022-12-07T08:25:13Z"],["dc.date.issued","2022-11-23"],["dc.date.updated","2022-12-07T06:37:25Z"],["dc.description.abstract","Purpose\r\nTo evaluate long-term continence rates (12 months) in patients after robot-assisted laparoscopic prostatectomy (RALP) in relation to their cognitive ability (CoAb), which proved to be a predictor for early post-prostatectomy incontinence.\r\n\r\nMaterial & Methods\r\nThis is the 12-month follow-up evaluation of our previously published observational single-center, prospective evaluation of 84 patients who underwent RALP as treatment of their localized prostate cancer between 07/2020 and 03/2021. Post-prostatectomy incontinence (PPI) was measured by asking patients about their 24 h pad usage, whereby 0 pads were considered continent and ≥1 pad was considered incontinent. CoAb was evaluated by performing the Mini-Mental State Examination prior to surgery. Possible predictors for PPI were evaluated using univariate and multivariable logistic regression models.\r\n\r\nResults\r\nMultivariable logistic regression analyses identified early incontinence status and nerve sparing (NS) as independent predictors for PPI after 12 months, resulting in a 5.69 times higher risk for PPI when the loss of urine was between 10 and 50 ml during the early performed pad test (one day after catheter removal) compared to 0–1 ml loss of urine [95% confidence interval (CI): 1.33–28.30, p = 0.024] and a 6.77 times higher risk for PPI, respectively, when only unilateral NS was performed compared to bilateral NS (95% CI: 1.79–30.89, p = 0.007). CoAb lost its predictive value for long-term PPI (p = 0.44).\r\n\r\nConclusion\r\nThe results of this study suggest that PPI is a dynamic, rather than a static condition with a dynamically changing pathophysiology within the first 12 months after RALP. Coping methods and therapies should adapt to this circumstance."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3389/fsurg.2022.1055880"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118457"],["dc.language.iso","en"],["dc.relation.eissn","2296-875X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Understanding long-term continence rates after robot-assisted laparoscopic prostatectomy – one-year follow-up on “Cognitive ability as a non-modifiable risk factor for post-prostatectomy urinary incontinence”"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e19725"],["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","Medicine"],["dc.bibliographiccitation.volume","99"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Biggemann, Lorenz"],["dc.contributor.author","Nietert, Manuel M."],["dc.contributor.author","Beißbarth, Tim"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Kim, Hyun S."],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Uhlig, Annemarie"],["dc.date.accessioned","2021-04-14T08:26:39Z"],["dc.date.available","2021-04-14T08:26:39Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1097/MD.0000000000019725"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17378"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82031"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1536-5964"],["dc.relation.issn","0025-7974"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Discriminating malignant and benign clinical T1 renal masses on computed tomography"],["dc.title.alternative","A pragmatic radiomics and machine learning approach"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","493"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","The Prostate"],["dc.bibliographiccitation.lastpage","501"],["dc.bibliographiccitation.volume","82"],["dc.contributor.affiliation","Uhlig, Annemarie; 1\r\nDepartment of Urology\r\nUniversity Medical Center Goettingen\r\nGoettingen Germany"],["dc.contributor.affiliation","Bremmer, Felix; 2\r\nDepartment of Pathology\r\nUniversity Medical Center Goettingen\r\nGoettingen Germany"],["dc.contributor.affiliation","Mut, Tuna Till; 1\r\nDepartment of Urology\r\nUniversity Medical Center Goettingen\r\nGoettingen Germany"],["dc.contributor.affiliation","Ahyai, Sascha; 1\r\nDepartment of Urology\r\nUniversity Medical Center Goettingen\r\nGoettingen Germany"],["dc.contributor.affiliation","Reichert, Mathias; 1\r\nDepartment of Urology\r\nUniversity Medical Center Goettingen\r\nGoettingen Germany"],["dc.contributor.affiliation","Leitsmann, Marianne; 1\r\nDepartment of Urology\r\nUniversity Medical Center Goettingen\r\nGoettingen Germany"],["dc.contributor.affiliation","Trojan, Lutz; 1\r\nDepartment of Urology\r\nUniversity Medical Center Goettingen\r\nGoettingen Germany"],["dc.contributor.affiliation","Popeneciu, Ionel‐Valentin; 1\r\nDepartment of Urology\r\nUniversity Medical Center Goettingen\r\nGoettingen Germany"],["dc.contributor.author","Leitsmann, Conrad"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Bremmer, Felix"],["dc.contributor.author","Mut, Tuna Till"],["dc.contributor.author","Ahyai, Sascha"],["dc.contributor.author","Reichert, Mathias"],["dc.contributor.author","Leitsmann, Marianne"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Popeneciu, Ionel‐Valentin"],["dc.date.accessioned","2022-02-01T10:31:29Z"],["dc.date.available","2022-02-01T10:31:29Z"],["dc.date.issued","2021"],["dc.date.updated","2022-03-20T23:34:50Z"],["dc.description.abstract","Abstract Background The aim of our study was to evaluate the impact of prostate biopsy technique (transrectal ultrasound (US)—prostate biopsy (PBx) versus multiparametric magnetic resonance imaging (mpMRI) targeted prostate biopsy (MRI‐PBx) on intraoperative nerve‐sparing and the rate of secondary neurovascular‐bundle resection (SNR) in patients undergoing robot‐assisted laparoscopic radical prostatectomy (RARP). A real‐time investigation with a frozen‐section examination (NeuroSAFE) microscopically excluded or confirmed prostate cancer invasion of the nerve structures resulting in preservation of the neurovascular bundle or SNR. Additionally, we analyzed risk factors related to SNR, such as longer operation time and postoperative complications. Methods The total study cohort was stratified according to non‐nerve‐sparing versus nerve‐sparing RARP. Patients with nerve‐sparing approach were then stratified according to biopsy technique (PBx vs. MRI‐PBx). Further, we compared PBx versus MRI‐PBx according to SNR rate. Results We included a total of 470 consecutive patients, who underwent RARP for PCa at our institution between January 2016 and December 2019. Patients with a preoperative MRI‐PBx had a 2.12‐fold higher chance of successful nerve‐sparing (without SNR) compared to patients with PBx (p < 0.01). Patients with preoperative MRI‐PBx required 73% less intraoperative SNR compared to patients with PBx (p < 0.0001). Prior MRI‐PBx is thus a predictor for successful nerve‐sparing RARP approach. Conclusion Preoperative MRI‐PBx led to better oncological outcomes and less SNR. Young patients with good erectile function could benefit from a preoperative MRI‐PBx before nerve‐sparing RARP."],["dc.identifier.doi","10.1002/pros.24295"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/98873"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-517"],["dc.relation.eissn","1097-0045"],["dc.relation.issn","0270-4137"],["dc.rights","This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made."],["dc.rights.uri","http://creativecommons.org/licenses/by-nc-nd/4.0/"],["dc.title","Impact of mpMRI targeted biopsy on intraoperative nerve‐sparing (NeuroSAFE) during robot‐assisted laparoscopic radical prostatectomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e15346"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","Medicine"],["dc.bibliographiccitation.volume","98"],["dc.contributor.author","Strauss, Arne"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Uhlig, Annemarie"],["dc.date.accessioned","2020-12-10T18:20:07Z"],["dc.date.available","2020-12-10T18:20:07Z"],["dc.date.issued","2019"],["dc.description.abstract","To assess whether left and right-sided renal cell carcinoma (RCC) carry side-specific outcomes.Surgically treated RCC patients were included from the United States Surveillance, Epidemiology and End Results database (Surveillance, Epidemiology and End Results database [SEER]; 2013 version) and the German Centre for Cancer Registry Data (ZfKD; 2000-2014). Bilateral RCC, those with missing RCC staging, follow-up time, and survival status were excluded. Cancer-specific survival (CSS) according to RCC side was compared using multivariable Cox regression.Seventeen thousand seven hundred nine SEER patients and 41,967 ZfKD patients were included. In both datasets, patients with left-sided RCC had higher T status and more often presented with nodal positive or metastatic disease. In the SEER dataset 1258 (14.33%) patients with left-sided RCC underwent lymphadenectomy (LAD), compared to 908 (10.17%) LADs in right-sided RCC (P <.001). CSS was inferior for left-sided in both datasets after multivariable adjustment (SEER HR = 1.187, 95% CI 1.048-1.345, P = .007, P = .008; ZfKD HR = 1.155, 95% CI 1.046-1.275, P = .004).In the SEER population, site-specific CSS differences were driven by whether or not a LAD was performed. Among SEER patients with LAD no statistically significant differences in laterality were observed (HR 1.096, 95% CI 0.8977-1.337, P = .396) whereas, in absence of LAD, CSS was shorter for individuals with left-sided tumor (HR = 1.176, 95%CI 1.002-1.38, P = .0468).Although the overall survival difference was only marginal, left-sided RCC in surgically treated patients tends to present at more advanced stage and has in general worse CSS, especially in patients without LAD. Site-specific lymphogenic spread patterns might contribute to these findings. Further prospective studies should evaluate, whether side-adapted LAD protocols influence outcomes in RCC patients."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2019"],["dc.identifier.doi","10.1097/MD.0000000000015346"],["dc.identifier.issn","0025-7974"],["dc.identifier.pmid","31027111"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16077"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75460"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.notes.intern","In goescholar not merged with http://resolver.sub.uni-goettingen.de/purl?gs-1/16329 but duplicate"],["dc.notes.status","final"],["dc.relation.eissn","1536-5964"],["dc.relation.haserratum","/handle/2/110673"],["dc.relation.issn","0025-7974"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.subject.ddc","610"],["dc.title","Tumor laterality in renal cancer as a predictor of survival in large patient cohorts: A STROBE compliant study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Urology"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Hinterthaner, Marc"],["dc.contributor.author","von Hammerstein-Equord, Alexander"],["dc.contributor.author","Strauss, Arne"],["dc.date.accessioned","2020-12-10T18:38:55Z"],["dc.date.available","2020-12-10T18:38:55Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1186/s12894-019-0544-7"],["dc.identifier.eissn","1471-2490"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16679"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77480"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Surgical approaches for treatment of ureteropelvic junction obstruction – a systematic review and network meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]