Bohnsack, Katherine E.

[["dc.bibliographiccitation.journal","Trends in Biochemical Sciences"],["dc.contributor.author","Bohnsack, Katherine E."],["dc.contributor.author","Kleiber, Nicole"],["dc.contributor.author","Lemus-Diaz, Nicolas"],["dc.contributor.author","Bohnsack, Markus T."],["dc.date.accessioned","2022-04-06T07:33:28Z"],["dc.date.available","2022-04-06T07:33:28Z"],["dc.date.issued","2022-03-29"],["dc.description.abstract","Modified nucleotides within cellular RNAs significantly influence their biogenesis, stability, and function. As reviewed here, 3-methylcytidine (m3C) has recently come to the fore through the identification of the methyltransferases responsible for installing m3C32 in human tRNAs. Mechanistic details of how m3C32 methyltransferases recognize their substrate tRNAs have been uncovered and the biogenetic and functional relevance of interconnections between m3C32 and modified adenosines at position 37 highlighted. Functional insights into the role of m3C32 modifications indicate that they influence tRNA structure and, consistently, lack of m3C32 modifications impairs translation. Development of quantitative, transcriptome-wide m3C mapping approaches and the discovery of an m3C demethylase reveal m3C to be dynamic, raising the possibility that it contributes to fine-tuning gene expression in different conditions."],["dc.identifier.doi","10.1016/j.tibs.2022.03.004"],["dc.identifier.pmid","35365384"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/106432"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/468"],["dc.identifier.url","https://sfb1190.med.uni-goettingen.de/production/literature/publications/174"],["dc.language.iso","en"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente"],["dc.relation","SFB 1190 | P04: Der GET-Rezeptor als ein Eingangstor zum ER und sein Zusammenspiel mit GET bodies"],["dc.relation.issn","0968-0004"],["dc.relation.workinggroup","RG M. Bohnsack (Molecular Biology)"],["dc.relation.workinggroup","RG K. Bohnsack (RNA Metabolism)"],["dc.rights","CC BY-NC-ND 4.0"],["dc.title","Roles and dynamics of 3-methylcytidine in cellular RNAs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","overview_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","8074"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","Nucleic Acids Research"],["dc.bibliographiccitation.lastpage","8089"],["dc.bibliographiccitation.volume","48"],["dc.contributor.author","Lemus-Diaz, Nicolas"],["dc.contributor.author","Ferreira, Rafael Rinaldi"],["dc.contributor.author","Bohnsack, Katherine E."],["dc.contributor.author","Gruber, Jens"],["dc.contributor.author","Bohnsack, Markus T."],["dc.date.accessioned","2021-04-14T08:24:14Z"],["dc.date.available","2021-04-14T08:24:14Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1093/nar/gkaa549"],["dc.identifier.pmid","32609813"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17489"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81210"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/53"],["dc.identifier.url","https://sfb1190.med.uni-goettingen.de/production/literature/publications/116"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente"],["dc.relation","SFB 1190 | P14: Die Rolle humaner Nucleoporine in Biogenese und Export makromolekularer Komplexe"],["dc.relation.eissn","1362-4962"],["dc.relation.issn","0305-1048"],["dc.relation.workinggroup","RG M. Bohnsack (Molecular Biology)"],["dc.relation.workinggroup","RG K. Bohnsack (RNA Metabolism)"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","The human box C/D snoRNA U3 is a miRNA source and miR-U3 regulates expression of sortin nexin 27"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]