Baudewig, Jürgen

[["dc.bibliographiccitation.firstpage","1721"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","NeuroReport"],["dc.bibliographiccitation.lastpage","1725"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Merboldt, Klaus-Dietmar"],["dc.contributor.author","Baudewig, Jürgen"],["dc.contributor.author","Treue, Stefan"],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2022-10-06T13:35:26Z"],["dc.date.available","2022-10-06T13:35:26Z"],["dc.date.issued","2002"],["dc.identifier.doi","10.1097/00001756-200210070-00006"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116095"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0959-4965"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Functional MRI of self-controlled stereoscopic depth perception"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","473"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.lastpage","481"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Baudewig, Juergen"],["dc.contributor.author","Kallenberg, Kai"],["dc.contributor.author","Kastrup, Andreas"],["dc.contributor.author","Merboldt, Klaus-Dietmar"],["dc.contributor.author","Dechent, Peter"],["dc.date.accessioned","2018-11-07T11:16:47Z"],["dc.date.available","2018-11-07T11:16:47Z"],["dc.date.issued","2008"],["dc.description.abstract","Functional magnetic resonance imaging (fMRI) based on blood oxygenation level dependent (BOLD) contrast is the most widely used technique for imaging human brain function. However, the dynamic interplay of altered cerebral blood flow (CBF), cerebral blood volume (CBV), and oxidative metabolism (CMRO2) is not yet fully understood. One of the characteristics of the BOLD response is the post-stimulation undershoot, that is increased deoxyhemoglobin, which has been suggested to originate from a delayed recovery of elevated CBV or CMRO2 to baseline. To investigate the CBV contribution to the post-stimulation BOLD undershoot, we performed bolus-tracking experiments using a paramagnetic contrast agent in eight healthy subjects at 3 T. In an initial BOLD experiment without contrast agent, we determined the individual hemodynamic responsiveness. In two separate experiments, we then evaluated the relative CBV (rCBV) during visual stimulation and the post-stimulation undershoot, respectively. The results confirm a pronounced rCBV increase during stimulation (31.4+/-8.6%), but reveal no change in rCBV relative to baseline in the post-stimulation phase (0.7+/-7.2%). This finding renders a CBV contribution to the BOLD MRI undershoot unlikely and - in conjunction with a rapid post-stimulation return of CBF to baseline - supports the idea of a prolonged elevation of oxidative metabolism. (C) 2007 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.neuroimage.2007.12.005"],["dc.identifier.isi","000254627700010"],["dc.identifier.pmid","18201912"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54672"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","1053-8119"],["dc.title","The post-stimulation undershoot in BOLD fMRI of human brain is not caused by elevated cerebral blood volume"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Baudewig, Juergen"],["dc.contributor.author","Siebner, Hartwig Roman"],["dc.contributor.author","Bestmann, Sven"],["dc.contributor.author","Tergau, Frithjof"],["dc.contributor.author","Tings, T."],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T09:01:54Z"],["dc.date.available","2018-11-07T09:01:54Z"],["dc.date.issued","2001"],["dc.format.extent","S1126"],["dc.identifier.isi","000169106301125"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24545"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.publisher.place","San diego"],["dc.relation.issn","1053-8119"],["dc.title","Is BOLD MRI sensitive to cortical activation by transcranial magnetic stimulation?"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Baudewig, Jürgen"],["dc.contributor.author","Nitsche, Michael Andreas"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T09:01:57Z"],["dc.date.available","2018-11-07T09:01:57Z"],["dc.date.issued","2001"],["dc.identifier.isi","000169106301126"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24558"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.publisher.place","San Diego"],["dc.title","Preceeding transcranial direct current stimulation modulates BOLD MRI responses to sensorimotor activation in humans"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","196"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Magnetic Resonance in Medicine"],["dc.bibliographiccitation.lastpage","201"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Baudewig, Juergen"],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T09:25:12Z"],["dc.date.available","2018-11-07T09:25:12Z"],["dc.date.issued","2001"],["dc.description.abstract","Blood oxygenation level dependent (BOLD) MRI was used to monitor modulations of human sensorimotor activity by prior transcranial direct current stimulation (tDCS), Activation maps for a right hand sequential finger opposition task were obtained for six subjects before as well as 0-5 min and 15-20 min after a 5-min period of 1 mA cathodal and, in a separate session, anodal tDCS of the left-hemispheric motor cortex, Cathodal tDCS resulted in a global decrease of the mean number of activated pixels by 38% (P < 0.01) 0-5 min after stimulation, which reduced to 28% (P < 0.05) 15-20 min after stimulation, A region-of-interest analysis revealed a 57% decrease of activated pixels (P < 0.001) in the supplementary motor area, but no change in the hand area of the primary motor cortex. Anodal tDCS yielded a nonsignificant 5% increase of activated pixels with no regional differences, These findings support the view that reduced neuroaxonal excitability after cathodal tDCS causes reduced brain activity, However, rather than affecting the primary sensorimotor input of an active task, the process appears to dampen those responses that rely on cortico-cortical connections and related processing. Magn Reson Med 45: 196-201, 2001. (C) 2001 Wiley-Liss, Inc."],["dc.identifier.doi","10.1002/1522-2594(200102)45:2<196::AID-MRM1026>3.0.CO;2-1"],["dc.identifier.isi","000166720300004"],["dc.identifier.pmid","11180425"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30008"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0740-3194"],["dc.title","Regional modulation of BOLD MRI responses to human sensorimotor activation by transcranial direct current stimulation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3543"],["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","Neuroreport"],["dc.bibliographiccitation.lastpage","3548"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Baudewig, Jürgen"],["dc.contributor.author","Siebner, Hartwig Roman"],["dc.contributor.author","Bestmann, Sven"],["dc.contributor.author","Tergau, Frithjof"],["dc.contributor.author","Tings, T."],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T11:24:12Z"],["dc.date.available","2018-11-07T11:24:12Z"],["dc.date.issued","2001"],["dc.description.abstract","The effects of repetitive transcranial magnetic stimulation (rTMS) on human brain activity and associated hemodynamics were investigated by blood-oxygenation-level-dependent (BOLD) MRI using echo-planar imaging at 2.0 T. Apart from bilateral activation of the auditory cortex by the audible rTMS discharges (23 bursts, 1 s duration, 10 Hz, 10-20 s interstimulus intervals), BOLD responses were restricted to cortical representations of actual finger movements performed either voluntarily or evoked by suprathreshold rTMS of the motor cortex. Neither subthreshold rTMS of the motor cortex nor suprathreshold rTMS of the lateral premotor cortex induced a detectable BOLD response. These findings suggest that neuronal depolarization as induced by rTMS modulates the spiking output of a brain area but does not automatically alter cerebral blood flow and oxygenation. The observation of BOLD MRI activations probably reflects the afferent intracortical processing of real movements. (C) 2001 Lippincott Williams & Wilkins."],["dc.identifier.doi","10.1097/00001756-200111160-00034"],["dc.identifier.isi","000172175000033"],["dc.identifier.pmid","11733708"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56351"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0959-4965"],["dc.title","Functional MRI of cortical activations induced by transcranial magnetic stimulation (TMS)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1196"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Clinical Neurophysiology"],["dc.bibliographiccitation.lastpage","1200"],["dc.bibliographiccitation.volume","112"],["dc.contributor.author","Baudewig, Jürgen"],["dc.contributor.author","Bittermann, Hans-Joachim"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T08:54:18Z"],["dc.date.available","2018-11-07T08:54:18Z"],["dc.date.issued","2001"],["dc.description.abstract","Objectives: Attempts to localize the source of epileptic activity by linking electroencephalographic (EEG) abnormalities to blued oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) signal alterations art: hampered mainly by EEG distortions during MRI, subject motion, and unknown hemodynamic response characteristics. Methods: Using T2 -weighted echo-planar imaging at 2.0 T (2 s temporal resolution, 2x2x4 mm(3) spatial resolution). this work demonstrates strategies to alleviate some of these problems while studying a patient who had ideopathic generalized epilepsy with polyspike and slow-wave complexes. Results: Continuous EEG recordings during dynamic MRI (500 ms scanning, 1500 ms delay) and post-examination derivation of an EEG reference function for MRI analysis revealed positive BOLD MRI responses with temporal characteristics similar to those obtained fur functional challenges. Conclusions: The ability to map focal epileptic activity and/or associated cognitive processing provides new potential fur both epilepsy research and clinical patient management. (C) 2001 Elsevier Science Ireland Ltd. All rights I reserved."],["dc.identifier.doi","10.1016/S1388-2457(01)00562-4"],["dc.identifier.isi","000169789400006"],["dc.identifier.pmid","11516731"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22638"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1388-2457"],["dc.title","Simultaneous EEG and functional MRI of epileptic activity: a case report"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]