Chaieb, Leila

[["dc.bibliographiccitation.artnumber","105927"],["dc.bibliographiccitation.journal","Neural Plasticity"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Antal, Andrea"],["dc.date.accessioned","2018-11-07T09:01:47Z"],["dc.date.available","2018-11-07T09:01:47Z"],["dc.date.issued","2011"],["dc.description.abstract","A 10-minute application of highfrequency (100-640 Hz) transcranial random noise stimulation (tRNS) over the primary motor cortex (M1) increases baseline levels of cortical excitability, lasting around 1 hr poststimulation Terney et al. (2008). We have extended previous work demonstrating this effect by decreasing the stimulation duration to 4, 5, and 6 minutes to assess whether a shorter duration of tRNS can also induce a change in cortical excitability. Single-pulse monophasic transcranial magnetic stimulation (TMS) was used to measure baseline levels of cortical excitability before and after tRNS. A 5- and 6-minute tRNS application induced a significant facilitation. 4-minute tRNS produced no significant aftereffects on corticospinal excitability. Plastic after effects after tRNS on corticospinal excitability require a minimal stimulation duration of 5 minutes. However, the duration of the aftereffect of 5-min tRNS is very short compared to previous studies using tRNS. Developing different transcranial stimulation techniques may be fundamental in understanding how excitatory and inhibitory networks in the human brain can be modulated and how each technique can be optimised for a controlled and effective application."],["dc.identifier.doi","10.1155/2011/105927"],["dc.identifier.isi","000295634500001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7728"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24517"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Hindawi Publishing Corporation"],["dc.relation.issn","0792-8483"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Evaluating Aftereffects of Short-Duration Transcranial Random Noise Stimulation on Cortical Excitability"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","67"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Frontiers in Psychiatry"],["dc.bibliographiccitation.lastpage","7"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Antal, A."],["dc.contributor.author","Terney, D."],["dc.contributor.author","Paulus, W."],["dc.date.accessioned","2019-07-09T11:53:38Z"],["dc.date.available","2019-07-09T11:53:38Z"],["dc.date.issued","2012"],["dc.description.abstract","Combined administration of transcranial direct current-stimulation (tDCS) with either pergolide (PER) or D-cycloserine (D-CYC) can prolong the excitability-diminishing effects of cathodal, or the excitability enhancing effect of anodal stimulation for up to 24 h poststimulation. However, it remains unclear whether the potentiation of the observed aftereffects is dominated just by the polarity and duration of the stimulation, or the dual application of combined stimulation and drug administration. The present study looks at whether the aftereffects of oral administration of PER (a D1/D2 agonist) or D-CYC (a partial NMDA receptor agonist), in conjunction with the short-duration antagonistic application of tDCS (either 5 min cathodal followed immediately by 5 min anodal or vice versa), that alone only induces short-lasting aftereffects, can modulate cortical excitability in healthy human subjects, as revealed by a single-pulse MEP (motor-evoked-potential) paradigm. Results indicate that the antagonistic application of tDCS induces short-term neuroplastic aftereffects that are dependent upon the order of the application of short-duration stimulation. The administration of D-CYC resulted in a marked inhibition of cortical excitability under the application of tDCS in both stimulation orders. Intake of PER resulted in an increase in cortical excitability in both stimulation orientations, but was non-significant compared to the placebo condition. These results indicate that the aftereffects of tDCS are dependent upon the order of stimulation applied, and also demonstrate the prolongation of tDCS aftereffects when combined with the administration of CNS active drugs."],["dc.identifier.doi","10.3389/fpsyt.2012.00067"],["dc.identifier.fs","588338"],["dc.identifier.pmid","22783210"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7844"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60469"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Frontiers Research Foundation"],["dc.relation.eissn","1664-0640"],["dc.rights","CC BY-NC 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/3.0"],["dc.title","Pharmacological Modulation of the Short-Lasting Effects of Antagonistic Direct Current-Stimulation Over the Human Motor Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","642"],["dc.bibliographiccitation.journal","Frontiers in Psychology"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Ambrus, Geza Gergely"],["dc.contributor.author","Chaieb, Leila"],["dc.date.accessioned","2018-11-07T09:38:51Z"],["dc.date.available","2018-11-07T09:38:51Z"],["dc.date.issued","2014"],["dc.description.abstract","Stimulation using weak electrical direct currents has shown to be capable of inducing polarity-dependent diminutions or elevations in motor and visual cortical excitability. The aim of the present study was to test if reading during transcranial direct current stimulation (tDCS) is able to modify stimulation-induced plasticity in the visual cortex. Phosphene thresholds (PTs) in 12 healthy subjects were recorded before and after 10 min of anodal, cathodal, and sham tDCS in combination with reading. Reading alone decreased PTs significantly, compared to the sham tDCS condition without reading. Interestingly, after both anodal and cathodal stimulation there was a tendency toward smaller PTs. Our results support the observation that tDCS-induced plasticity is highly dependent on the cognitive state of the subject during stimulation, not only in the case of motor cortex but also in the case of visual cortex stimulation."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2014"],["dc.identifier.doi","10.3389/fpsyg.2014.00642"],["dc.identifier.isi","000338686500001"],["dc.identifier.pmid","24999339"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10461"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33151"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1664-1078"],["dc.relation.issn","1664-1078"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","Toward unraveling reading-related modulations of tDCS-induced neuroplasticity in the human visual cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Neuroscience and Rehabilitation"],["dc.bibliographiccitation.volume","1"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Moliadze, Vera"],["dc.contributor.author","Zarrouki, Driss"],["dc.contributor.author","Shoukier, Moneef"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2016-08-04T08:38:52Z"],["dc.date.accessioned","2021-10-27T13:20:37Z"],["dc.date.available","2016-08-04T08:38:52Z"],["dc.date.available","2021-10-27T13:20:37Z"],["dc.date.issued","2014"],["dc.description.abstract","Background: The brain-derived neurotrophic factor (BDNF) gene is involved in mechanisms of synaptic plasticity in the brain and has been demonstrated to also play a role in influencing brain plasticity induced by transcranial magnetic and electrical stimulation. Objective and methods: This is an update of a previous study from our laboratory. We retrospectively analysed the data of 115 healthy subjects participating in 130 experimental sessions, measuring the amplitude of motor evoked potentials (MEPs) before and after transcranial stimulation of the primary motor cortex (M1). We explored whether BDNF polymorphism shapes the effects of excitatory theta burst stimulation (iTBS, n=23), anodal (n=32) and cathodal (n=19) transcranial direct current (tDCS), random noise (tRNS, n=33) and alternating current (tACS, n=13) stimulation. Results: Although a trend toward altered plasticity was observed in Val- 66Met allele carriers to stimulation with regard to all protocols compared with the response of Val66Val individuals, no significant GENOTYPE x TIME interaction was found. Conclusions: The BDNF polymorphism is suggested to have an impact on transcranial stimulation-induced plasticity in humans, which differs according to the mechanism of plasticity induction. However, according to our data, we suggest that genotyping in general, in transcranial stimulation studies including small number of subjects and at least when the M1 is stimulated, is not necessary. Nevertheless, the impact of BDNF on plasticity inducing protocols might be taken into account for e.g. in cognitive studies, when the prefrontal cortex is stimulated."],["dc.identifier.doi","10.17653/2374-9091.SS0004"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13522"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91970"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.issn","2374-9091"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","BDNF Gene Polymorphisms and Motor Cortical Plasticity in Healthy Humans: When Should We Consider It"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","125"],["dc.bibliographiccitation.journal","Frontiers in Neuroscience"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T09:58:35Z"],["dc.date.available","2018-11-07T09:58:35Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Application of transcranial random noise stimulation (tRNS) between 0.1 and 640 Hz of the primary motor cortex (M1) for 10 min induces a persistent excitability increase lasting for at least 60 min. However, the mechanism of tRNS-induced cortical excitability alterations is not yet fully understood. Objective: The main aim of this study was to get first efficacy data with regard to the possible neuronal effect of tRNS. Methods: Single-pulse transcranial magnetic stimulation (TMS) was used to measure levels of cortical excitability before and after combined application of tRNS at an intensity of 1 mA for 10 min stimulation duration and a pharmacological agent (or sham) on eight healthy male participants. Results: The sodium channel blocker carbamazepine showed a tendency toward inhibiting MEPs 5-60 min poststimulation. The GABA(A) agonist lorazepam suppressed tRNS-induced cortical excitability increases at 0-20 and 60 min time points. The partial NMDA receptor agonist D-cycloserine, the NMDA receptor antagonist dextromethorphan and the D-2/D-3 receptor agonist ropinirole had no significant effects on the excitability increases seen with tRNS. Conclusions: In contrast to transcranial direct current stimulation (tDCS), aftereffects of tRNS are seem to be not NMDA receptor dependent and can be suppressed by benzodiazepines suggesting that tDCS and tRNS depend upon different mechanisms."],["dc.description.sponsorship","Open Access Publikationsfonds 2015"],["dc.identifier.doi","10.3389/fnins.2015.00125"],["dc.identifier.isi","000352977200001"],["dc.identifier.pmid","25914617"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11860"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37389"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1662-453X"],["dc.relation.issn","1662-453X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Transcranial random noise stimulation-induced plasticity is NMDA-receptor independent but sodium-channel blocker and benzodiazepines sensitive"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","147"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Frontiers in Behavioral Neuroscience"],["dc.bibliographiccitation.lastpage","8"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Masurat, Florentin"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2018-10-10T11:37:37Z"],["dc.date.available","2018-10-10T11:37:37Z"],["dc.date.issued","2015"],["dc.description.abstract","Near-infrared light stimulation of the brain has been claimed to improve deficits caused by traumatic brain injury and stroke. Here, we exploit the effect of transcranial near-infrared stimulation (tNIRS) as a tool to modulate cortical excitability in the healthy human brain. tNIRS was applied at a wavelength of 810 nm for 10 min over the hand area of the primary motor cortex (M1). Both single-pulse and paired-pulse measures of transcranial magnetic stimulation (TMS) were used to assess levels of cortical excitability in the corticospinal pathway and intracortical circuits. The serial reaction time task (SRTT) was used to investigate the possible effect of tNIRS on implicit learning. By evaluating the mean amplitude of single-pulse TMS elicited motor-evoked-potentials (MEPs) a significant decrease of the amplitude was observed up to 30 min post-stimulation, compared to baseline. Furthermore, the short interval cortical inhibition (SICI) was increased and facilitation (ICF) decreased significantly after tNIRS. The results from the SRTT experiment show that there was no net effect of stimulation on the performance of the participants. Results of a study questionnaire demonstrated that tNIRS did not induce serious side effects apart from light headache and fatigue. Nevertheless, 66% were able to detect the difference between active and sham stimulation conditions. In this study we provide further evidence that tNIRS is suitable as a tool for influencing cortical excitability and activity in the healthy human brain."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2015"],["dc.identifier.doi","10.3389/fnbeh.2015.00147"],["dc.identifier.pmid","26082699"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12012"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15958"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","14147"],["dc.bibliographiccitation.issue","52"],["dc.bibliographiccitation.journal","Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","14155"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Terney, Daniella"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Moliadze, Vera"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T11:07:51Z"],["dc.date.available","2018-11-07T11:07:51Z"],["dc.date.issued","2008"],["dc.description.abstract","For > 20 years, noninvasive transcranial stimulation techniques like repetitive transcranial magnetic stimulation (rTMS) and direct current stimulation (tDCS) have been used to induce neuroplastic-like effects in the human cortex, leading to the activity-dependent modification of synaptic transmission. Here, we introduce a novel method of electrical stimulation: transcranial random noise stimulation (tRNS), whereby a random electrical oscillation spectrum is applied over the motor cortex. tRNS induces consistent excitability increases lasting 60 min after stimulation. These effects have been observed in 80 subjects through both physiological measures and behavioral tasks. Higher frequencies (100-640 Hz) appear to be responsible for generating this excitability increase, an effect that may be attributed to the repeated opening of Na(+) channels. In terms of efficacy tRNS appears to possess at least the same therapeutic potential as rTMS/tDCS in diseases such as depression, while furthermore avoiding the constraint of current flow direction sensitivity characteristic of tDCS."],["dc.identifier.doi","10.1523/JNEUROSCI.4248-08.2008"],["dc.identifier.isi","000261985900014"],["dc.identifier.pmid","19109497"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6239"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52675"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Soc Neuroscience"],["dc.relation.issn","0270-6474"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Increasing Human Brain Excitability by Transcranial High-Frequency Random Noise Stimulation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","77"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Visual Neuroscience"],["dc.bibliographiccitation.lastpage","81"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T11:20:52Z"],["dc.date.available","2018-11-07T11:20:52Z"],["dc.date.issued","2008"],["dc.description.abstract","Transcranial direct current stimulation (tDCS) is a non-invasive method of modulating levels of cortical excitability. In this study, data gathered over a number of previously conducted experiments before and after tDCS, has been re-analyzed to investigate correlations between sex differences with respect to neuroplastic effects. Visual evoked potentials (VEPs), phosphene thresholds (PTs), and contrast sensitivity measurements (CSs) are used as indicators of the excitability of the primary visual cortex. The data revealed that cathodally induced excitability effects 10 min post stimulation with tDCS, showed no significant difference between genders. However, stimulation in the anodal direction revealed sex-specific effects: in women, anodal stimulation heightened cortical excitability significantly when compared to the age-matched male subject group. There was no significant difference between male and female subjects immediately after stimulation. These results indicate that sex differences exist within the visual cortex of humans, and may be subject to the influences of modulatory neurotransmitters or gonadal hormones which mirror short-term neuroplastic effects."],["dc.identifier.doi","10.1017/S0952523808080097"],["dc.identifier.isi","000253623700008"],["dc.identifier.pmid","18282312"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9059"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55641"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cambridge Univ Press"],["dc.relation.issn","0952-5238"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Gender-specific modulation of short-term neuroplasticity in the visual cortex induced by transcranial direct current stimulation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","888"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Brain Sciences"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Bischoff, Rebecca"],["dc.contributor.author","Stephani, Caspar"],["dc.contributor.author","Czesnik, Dirk"],["dc.contributor.author","Klinker, Florian"],["dc.contributor.author","Timäus, Charles"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2021-04-14T08:31:09Z"],["dc.date.available","2021-04-14T08:31:09Z"],["dc.date.issued","2020"],["dc.description.sponsorship","Migraine Research Foundation"],["dc.identifier.doi","10.3390/brainsci10110888"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17667"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83498"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","MDPI"],["dc.relation.eissn","2076-3425"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Low Intensity, Transcranial, Alternating Current Stimulation Reduces Migraine Attack Burden in a Home Application Set-Up: A Double-Blinded, Randomized Feasibility Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1839"],["dc.bibliographiccitation.issue","23"],["dc.bibliographiccitation.journal","Current Biology"],["dc.bibliographiccitation.lastpage","1843"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Kanai, Ryota"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Walsh, Vincent"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T11:08:03Z"],["dc.date.available","2018-11-07T11:08:03Z"],["dc.date.issued","2008"],["dc.description.abstract","Noninvasive cortical stimulation techniques, such as transcranial magnetic stimulation (TMS) [1, 2] and transcranial direct current stimulation (tDCS) [3-6], have proved to be powerful tools for establishing causal relationships between brain regions and their functions [1, 2]. In the present study, we demonstrate that a new technique called transcranial alternating current stimulation (tACS) [7] can interact with ongoing rhythmic activities in the visual cortex in a frequency-specific fashion and induce visual experiences (phosphenes). We delivered an oscillatory current over the occipital cortex with tACS. In order to observe interactions with ongoing cortical rhythms, we compared the effects of delivering tACS under conditions of light (\"Light\" condition) or darkness (\"Dark\" condition). Stimulation over the occipital cortex induced perception of continuously flickering light most effectively when the beta frequency range was applied in an illuminated room, whereas the most effective stimulation frequency shifted to the alpha frequency range during testing in darkness. Stimulation with theta or gamma frequencies did not produce any visual phenomena. The shift of the effective stimulation frequency indicates that the frequency dependency is caused by interactions with ongoing oscillatory activity in the stimulated cortex. Our results suggest that tACS can be used as a noninvasive tool for establishing a causal link between rhythmic cortical activities and their functions."],["dc.identifier.doi","10.1016/j.cub.2008.10.027"],["dc.identifier.isi","000261721100024"],["dc.identifier.pmid","19026538"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6233"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52705"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.relation.issn","1879-0445"],["dc.relation.issn","0960-9822"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Frequency-Dependent Electrical Stimulation of the Visual Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]