Knauf, Sascha

[["dc.bibliographiccitation.journal","Frontiers in Microbiology"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Hallmaier-Wacker, Luisa K."],["dc.contributor.author","Lüert, Simone"],["dc.contributor.author","Gronow, Sabine"],["dc.contributor.author","Spröer, Cathrin"],["dc.contributor.author","Overmann, Jörg"],["dc.contributor.author","Buller, Nicky"],["dc.contributor.author","Vaughan-Higgins, Rebecca J."],["dc.contributor.author","Knauf, Sascha"],["dc.date.accessioned","2020-12-10T18:44:27Z"],["dc.date.available","2020-12-10T18:44:27Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.3389/fmicb.2019.02094"],["dc.identifier.eissn","1664-302X"],["dc.identifier.pmid","31552004"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16796"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78462"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.relation.haserratum","/handle/2/78462"],["dc.relation.haserratum","/handle/2/78465"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","A Metataxonomic Tool to Investigate the Diversity of Treponema"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","7"],["dc.bibliographiccitation.journal","Current Opinion in Virology"],["dc.bibliographiccitation.lastpage","12"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Richard, Mathilde"],["dc.contributor.author","Knauf, Sascha"],["dc.contributor.author","Lawrence, Philip"],["dc.contributor.author","Mather, Alison E."],["dc.contributor.author","Munster, Vincent J."],["dc.contributor.author","Müller, Marcel A."],["dc.contributor.author","Smith, Derek"],["dc.contributor.author","Kuiken, Thijs"],["dc.date.accessioned","2019-07-09T11:43:19Z"],["dc.date.available","2019-07-09T11:43:19Z"],["dc.date.issued","2017"],["dc.description.abstract","The pandemic potential of zoonotic pathogens lies in their ability to become efficiently transmissible amongst humans. Here, we focus on contact-transmitted pathogens and discuss the factors, at the pathogen, host and environmental levels that promote or hinder their human-to-human transmissibility via the following modes of contact transmission: skin contact, sexual contact, respiratory contact and multiple route contact. Factors common to several modes of transmission were immune evasion, high viral load, low infectious dose, crowding, promiscuity, and co-infections; other factors were specific for a pathogen or mode of contact transmission. The identification of such factors will lead to a better understanding of the requirements for human-to-human spread of pathogens, as well as improving risk assessment of newly emerging pathogens."],["dc.identifier.doi","10.1016/j.coviro.2016.11.004"],["dc.identifier.pmid","27907884"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14430"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58861"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/278976/EU/ANTIcipating the Global Onset of Novel Epidemics/ANTIGONE"],["dc.relation.issn","1879-6257"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Factors determining human-to-human transmissibility of zoonotic pathogens via contact"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","725"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Veterinary Science"],["dc.bibliographiccitation.lastpage","734"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Knauf, Yvonne"],["dc.contributor.author","Köhler, Kernt"],["dc.contributor.author","Knauf, Sascha"],["dc.contributor.author","Wehrend, Axel"],["dc.date.accessioned","2019-07-09T11:49:51Z"],["dc.date.available","2019-07-09T11:49:51Z"],["dc.date.issued","2018"],["dc.description.abstract","Ovaries of 21 bitches presented with gynecopathies were surgically removed and histologically examined. Standard histological, as well as immunohistochemical, classification of 193 cystic structures resulted in the classification of 72 cysts of subsurface epithelial structures (SES), 61 follicular cysts (FCs), 38 cystic rete ovarii (CRO), 13 lutein cysts (LCs), and 9 non-classifiable cysts (NCCs). In addition to the histological classification, results were interpreted according to subject medical history, clinical examination outcome, and macroscopic observations during ovariohysterectomy. Dogs with ovarian cysts (OCs) and associated reproductive perturbations were mostly nulliparous, of large breed, and had an average of 9.5 ± 3 years. Prolonged or shortened inter-estrus intervals of past heats, however, seemed to be relatively low-risk factors for the development of OCs in dogs. Furthermore, we provide histological observations of a rarely seen canine LC including a degenerated oocyte in the central cavity."],["dc.identifier.doi","10.4142/jvs.2018.19.6.725"],["dc.identifier.pmid","30304884"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15795"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59645"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1976-555X"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.subject.ddc","630"],["dc.title","Histological classification of canine ovarian cyst types with reference to medical history"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Chuma, Idrissa S."],["dc.contributor.author","Roos, Christian"],["dc.contributor.author","Atickem, Anagaw"],["dc.contributor.author","Bohm, Torsten"],["dc.contributor.author","Anthony Collins, D."],["dc.contributor.author","Grillová, Linda"],["dc.contributor.author","Hallmaier-Wacker, Luisa K."],["dc.contributor.author","Kazwala, Rudovick R."],["dc.contributor.author","Keyyu, Julius D."],["dc.contributor.author","Lüert, Simone"],["dc.contributor.author","Maloueki, Ulrich"],["dc.contributor.author","Oppelt, Jan"],["dc.contributor.author","Petrželková, Klára J."],["dc.contributor.author","Piel, Alexander"],["dc.contributor.author","Stewart, Fiona A."],["dc.contributor.author","Šmajs, David"],["dc.contributor.author","Knauf, Sascha"],["dc.date.accessioned","2020-12-10T18:11:07Z"],["dc.date.available","2020-12-10T18:11:07Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1038/s41598-019-50779-9"],["dc.identifier.eissn","2045-2322"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16516"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73902"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Strain diversity of Treponema pallidum subsp. pertenue suggests rare interspecies transmission in African nonhuman primates"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0003637"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PLoS neglected tropical diseases"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Knauf, Sascha"],["dc.contributor.author","Dahlmann, Franziska"],["dc.contributor.author","Batamuzi, Emmanuel K."],["dc.contributor.author","Frischmann, Sieghard"],["dc.contributor.author","Liu, Hsi"],["dc.date.accessioned","2019-07-09T11:42:32Z"],["dc.date.available","2019-07-09T11:42:32Z"],["dc.date.issued","2015-03-01"],["dc.description.abstract","There is evidence to suggest that the yaws bacterium (Treponema pallidum ssp. pertenue) may exist in non-human primate populations residing in regions where yaws is endemic in humans. Especially in light of the fact that the World Health Organizaiton (WHO) recently launched its second yaws eradication campaign, there is a considerable need for reliable tools to identify treponemal infection in our closest relatives, African monkeys and great apes. It was hypothesized that commercially available serological tests detect simian anti-T. pallidum antibody in serum samples of baboons, with comparable sensitivity and specificity to their results on human sera. Test performances of five different treponemal tests (TTs) and two non-treponemal tests (NTTs) were evaluated using serum samples of 57 naturally T. pallidum-infected olive baboons (Papio anubis) from Lake Manyara National Park in Tanzania. The T. pallidum particle agglutination assay (TP-PA) was used as a gold standard for comparison. In addition, the overall infection status of the animals was used to further validate test performances. For most accurate results, only samples that originated from baboons of known infection status, as verified in a previous study by clinical inspection, PCR and immunohistochemistry, were included. All tests, TTs and NTTs, used in this study were able to reliably detect antibodies against T. pallidum in serum samples of infected baboons. The sensitivity of TTs ranged from 97.7-100%, while specificity was between 88.0-100.0%. The two NTTs detected anti-lipoidal antibodies in serum samples of infected baboons with a sensitivity of 83.3% whereas specificity was 100%. For screening purposes, the TT Espline TP provided the highest sensitivity and specificity and at the same time provided the most suitable format for use in the field. The enzyme immune assay Mastblot TP (IgG), however, could be considered as a confirmatory test."],["dc.identifier.doi","10.1371/journal.pntd.0003637"],["dc.identifier.pmid","25803295"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13558"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58687"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1935-2735"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.mesh","Agglutination Tests"],["dc.subject.mesh","Animals"],["dc.subject.mesh","Antibodies, Bacterial"],["dc.subject.mesh","Monkey Diseases"],["dc.subject.mesh","Papio"],["dc.subject.mesh","Sensitivity and Specificity"],["dc.subject.mesh","Serologic Tests"],["dc.subject.mesh","Tanzania"],["dc.subject.mesh","Treponema pallidum"],["dc.subject.mesh","Yaws"],["dc.title","Validation of serological tests for the detection of antibodies against Treponema pallidum in nonhuman primates."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e0202303"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Zinner, Dietmar"],["dc.contributor.author","Atickem, Anagaw"],["dc.contributor.author","Beehner, Jacinta C."],["dc.contributor.author","Bekele, Afework"],["dc.contributor.author","Bergman, Thore J."],["dc.contributor.author","Burke, Ryan"],["dc.contributor.author","Dolotovskaya, Sofya"],["dc.contributor.author","Fashing, Peter J."],["dc.contributor.author","Gippoliti, Spartaco"],["dc.contributor.author","Knauf, Sascha"],["dc.contributor.author","Knauf, Yvonne"],["dc.contributor.author","Mekonnen, Addisu"],["dc.contributor.author","Moges, Amera"],["dc.contributor.author","Nguyen, Nga"],["dc.contributor.author","Stenseth, Nils Chr."],["dc.contributor.author","Roos, Christian"],["dc.contributor.editor","Chiang, Tzen-Yuh"],["dc.date.accessioned","2020-12-10T18:42:08Z"],["dc.date.available","2020-12-10T18:42:08Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1371/journal.pone.0202303"],["dc.identifier.eissn","1932-6203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15692"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77820"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Phylogeography, mitochondrial DNA diversity, and demographic history of geladas (Theropithecus gelada)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e50989"],["dc.bibliographiccitation.journal","eLife"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Fischer, Julia"],["dc.contributor.author","Barrett, Louise"],["dc.contributor.author","Collins, Anthony"],["dc.contributor.author","Elton, Sarah"],["dc.contributor.author","Fagot, Joël"],["dc.contributor.author","Ferreira da Silva, Maria Joana"],["dc.contributor.author","Hammerschmidt, Kurt"],["dc.contributor.author","Henzi, Peter"],["dc.contributor.author","Knauf, Sascha"],["dc.contributor.author","Kopp, Gisela H"],["dc.contributor.author","Rogers, Jeffrey"],["dc.contributor.author","Roos, Christian"],["dc.contributor.author","Ross, Caroline"],["dc.contributor.author","Silk, Joan"],["dc.contributor.author","Snyder-Mackler, Noah"],["dc.contributor.author","Staedele, Veronika"],["dc.contributor.author","Swedell, Larissa"],["dc.contributor.author","Zinner, Dietmar"],["dc.contributor.author","Higham, James P."],["dc.contributor.author","Alberts, Susan C."],["dc.contributor.author","Beehner, Jacinta C."],["dc.contributor.author","Bergman, Thore J."],["dc.contributor.author","Carter, Alecia J."],["dc.contributor.author","Jolly, Clifford J."],["dc.contributor.author","Seyfarth, Robert M."],["dc.contributor.author","Wilson, Michael L."],["dc.date.accessioned","2020-12-10T18:48:08Z"],["dc.date.available","2020-12-10T18:48:08Z"],["dc.date.issued","2019"],["dc.description.abstract","Baboons, members of the genus Papio, comprise six closely related species distributed throughout sub-Saharan Africa and southwest Arabia. The species exhibit more ecological flexibility and a wider range of social systems than many other primates. This article summarizes our current knowledge of the natural history of baboons and highlights directions for future research. We suggest that baboons can serve as a valuable model for complex evolutionary processes, such as speciation and hybridization. The evolution of baboons has been heavily shaped by climatic changes and population expansion and fragmentation in the African savanna environment, similar to the processes that acted during human evolution. With accumulating long-term data, and new data from previously understudied species, baboons are ideally suited for investigating the links between sociality, health, longevity and reproductive success. To achieve these aims, we propose a closer integration of studies at the proximate level, including functional genomics, with behavioral and ecological studies."],["dc.identifier.doi","10.7554/eLife.50989"],["dc.identifier.eissn","2050-084X"],["dc.identifier.pmid","31711570"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16961"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/79034"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","2050-084X"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Insights into the evolution of social systems and species from baboon studies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","463"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Reproduction in domestic animals = Zuchthygiene"],["dc.bibliographiccitation.lastpage","468"],["dc.bibliographiccitation.volume","49"],["dc.contributor.author","Knauf, Y."],["dc.contributor.author","Bostedt, H."],["dc.contributor.author","Failing, K."],["dc.contributor.author","Knauf, S."],["dc.contributor.author","Wehrend, A."],["dc.date.accessioned","2019-07-09T11:42:05Z"],["dc.date.available","2019-07-09T11:42:05Z"],["dc.date.issued","2014-06-01"],["dc.description.abstract","A total of 73 bitches with ovarian cysts were ovariohysterectomized. Cysts were characterized by gross pathology and endocrine parameters. Therefore, oestradiol-17ß and progesterone concentrations were assessed in cyst-fluid and corresponding blood plasma in each bitch. Our data demonstrated that multiple cysts were often present in a single individual (82%) and that cysts were commonly found on both ovaries (77%). The number of cysts per individual varied from 1 to 35. Most cysts were small in size (range 0.2-4.0 cm in diameter). No cyst was found to produce solely oestradiol-17ß or progesterone. Plasma levels of oestradiol-17ß and progesterone for a given individual were positively correlated with levels of these same hormones in their cyst-fluid (r = 0.334 and p = 0.001 for oestradiol-17ß; r = 0.419 and p < 0.001 for progesterone). Our study is the first to provide a comprehensive evaluation of the gross pathology and endocrinology of ovarian cysts in a larger number of bitches."],["dc.identifier.doi","10.1111/rda.12311"],["dc.identifier.pmid","24698026"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12827"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58588"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1439-0531"],["dc.rights","CC BY-NC-ND 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/3.0"],["dc.subject.mesh","Animals"],["dc.subject.mesh","Dog Diseases"],["dc.subject.mesh","Dogs"],["dc.subject.mesh","Estradiol"],["dc.subject.mesh","Female"],["dc.subject.mesh","Ovarian Cysts"],["dc.subject.mesh","Progesterone"],["dc.title","Gross pathology and endocrinology of ovarian cysts in bitches."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0006396"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","PLoS Neglected Tropical Diseases"],["dc.bibliographiccitation.lastpage","14"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Knauf, Sascha"],["dc.contributor.author","Lüert, Simone"],["dc.contributor.author","Šmajs, David"],["dc.contributor.author","Strouhal, Michal"],["dc.contributor.author","Chuma, Idrissa S."],["dc.contributor.author","Frischmann, Sieghard"],["dc.contributor.author","Bakheit, Mohammed"],["dc.date.accessioned","2018-11-16T10:48:50Z"],["dc.date.accessioned","2021-10-27T13:13:17Z"],["dc.date.available","2018-11-16T10:48:50Z"],["dc.date.available","2021-10-27T13:13:17Z"],["dc.date.issued","2018"],["dc.description.abstract","We show proof of concept for gene targets (polA, tprL, and TP_0619) that can be used in loop-mediated isothermal amplification (LAMP) assays to rapidly differentiate infection with any of the three Treponema pallidum subspecies (pallidum (TPA), pertenue (TPE), and endemicum (TEN)) and which are known to infect humans and nonhuman primates (NHPs). Four TPA, six human, and two NHP TPE strains, as well as two human TEN strains were used to establish and validate the LAMP assays. All three LAMP assays were highly specific for the target DNA. Amplification was rapid (5–15 min) and within a range of 10E+6 to 10E+2 of target DNA molecules. Performance in NHP clinical samples was similar to the one seen in human TPE strains. The newly designed LAMP assays provide proof of concept for a diagnostic tool that enhances yaws clinical diagnosis. It is highly specific for the target DNA and does not require expensive laboratory equipment. Test results can potentially be interpreted with the naked eye, which makes it suitable for the use in remote clinical settings."],["dc.identifier.doi","10.1371/journal.pntd.0006396"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15670"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91766"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.issn","1935-2735"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Gene target selection for loop-mediated isothermal amplification for rapid discrimination of Treponema pallidum subspecies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Hallmaier-Wacker, L. K."],["dc.contributor.author","Lüert, S."],["dc.contributor.author","Roos, C."],["dc.contributor.author","Knauf, S."],["dc.date.accessioned","2020-12-10T18:11:09Z"],["dc.date.available","2020-12-10T18:11:09Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1038/s41598-019-53976-8"],["dc.identifier.eissn","2045-2322"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16925"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73909"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Lactation and menstruation shift the vaginal microbiota in captive rhesus monkeys to be more similar to the male urethral microbiota"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]