Antal, Andrea

[["dc.bibliographiccitation.firstpage","2287"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.lastpage","2296"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Polania, Rafael"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Nitsche, Michael A."],["dc.date.accessioned","2018-11-07T08:59:55Z"],["dc.date.available","2018-11-07T08:59:55Z"],["dc.date.issued","2011"],["dc.description.abstract","Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that alters cortical excitability and activity in a polarity-dependent way. Stimulation for a few minutes has been shown to induce plastic alterations of cortical excitability and to improve cognitive performance. These effects might be related to stimulation-induced alterations of functional cortical network connectivity. We aimed to investigate the impact of tDCS on cortical network function by functional connectivity and graph theoretical analysis of the BOLD fMRI spontaneous activity. fMRI resting-state datasets were acquired immediately before and after 10-min bipolar tDCS during rest, with the anode placed over the left primary motor cortex (M1) and the cathode over the contralateral frontopolar cortex. For each dataset, grey matter voxel-based synchronization matrices were calculated and thresholded to construct undirected graphs. Nodal connectivity degree and minimum path length maps were calculated and compared before and after tDCS. Nodal minimum path lengths significantly increased in the left somatomotor (SM1) cortex after anodal tDCS, which means that the number of direct functional connections from the left SM1 to topologically distant grey matter voxels significantly decreased. In contrast, functional coupling between premotor and superior parietal areas with the left SM1 significantly increased. Additionally, the nodal connectivity degree in the left posterior cingulate cortex (PCC) area as well as in the right dorsolateral prefrontal cortex (right DLPFC) significantly increased. In summary, we provide initial support that tDCS-induced neuroplastic alterations might be related to functional connectivity changes in the human brain. Additionally, we propose our approach as a powerful method to track for neuroplastic changes in the human brain. (C) 2010 Elsevier Inc. All rights reserved."],["dc.description.sponsorship","Rose Foundation"],["dc.identifier.doi","10.1016/j.neuroimage.2010.09.085"],["dc.identifier.isi","000286302000051"],["dc.identifier.pmid","20932916"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24019"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","1053-8119"],["dc.title","Introducing graph theory to track for neuroplastic alterations in the resting human brain: A transcranial direct current stimulation study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2220"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Clinical Neurophysiology"],["dc.bibliographiccitation.lastpage","2222"],["dc.bibliographiccitation.volume","114"],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Liebetanz, David"],["dc.contributor.author","Lang, N."],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Tergau, Frithjof"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:34:56Z"],["dc.date.available","2018-11-07T10:34:56Z"],["dc.date.issued","2003"],["dc.identifier.doi","10.1016/S1388-2457(03)00235-9"],["dc.identifier.isi","000186563700026"],["dc.identifier.pmid","14580622"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44984"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Sci Ireland Ltd"],["dc.relation.issn","1388-2457"],["dc.title","Safety criteria for transcranial direct current stimulation (tDCS) in humans"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1349"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","1366"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Bikson, Marom"],["dc.contributor.author","Esmaeilpour, Zeinab"],["dc.contributor.author","Adair, Devin"],["dc.contributor.author","Kronberg, Greg"],["dc.contributor.author","Tyler, William J."],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Datta, Abhishek"],["dc.contributor.author","Sabel, Bernhard A."],["dc.contributor.author","Nitsche, Michael A."],["dc.contributor.author","Loo, Colleen"],["dc.contributor.author","Edwards, Dylan"],["dc.contributor.author","Ekhtiari, Hamed"],["dc.contributor.author","Knotkova, Helena"],["dc.contributor.author","Woods, Adam J."],["dc.contributor.author","Hampstead, Benjamin M."],["dc.contributor.author","Badran, Bashar W."],["dc.contributor.author","Peterchev, Angel V."],["dc.date.accessioned","2020-12-10T14:22:48Z"],["dc.date.available","2020-12-10T14:22:48Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.brs.2019.07.010"],["dc.identifier.issn","1935-861X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71741"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Transcranial electrical stimulation nomenclature"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","5782"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Investigative Ophthalmology & Visual Science"],["dc.bibliographiccitation.lastpage","5787"],["dc.bibliographiccitation.volume","48"],["dc.contributor.author","Lang, Nicolas"],["dc.contributor.author","Siebner, Hartwig Roman"],["dc.contributor.author","Chadaide, Zoltan"],["dc.contributor.author","Boros, Klara"],["dc.contributor.author","Nitsche, Michael A."],["dc.contributor.author","Rothwell, John C."],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Antal, Andrea"],["dc.date.accessioned","2018-11-07T10:48:26Z"],["dc.date.available","2018-11-07T10:48:26Z"],["dc.date.issued","2007"],["dc.description.abstract","PURPOSE. In the motor cortex (M1), transcranial direct current stimulation (tDCS) can effectively prime excitability changes that are evoked by a subsequent train of repetitive transcranial magnetic stimulation (rTMS). The authors examined whether tDCS can also prime the cortical response to rTMS in the human visual cortex. METHODS. In nine healthy subjects, the authors applied tDCS ( 10 minutes; +/- 1 mA) to the occipital cortex. After tDCS, they applied a 20-second train of 5 Hz rTMS at 90% of phosphene threshold ( PT) intensity. A similar rTMS protocol had previously demonstrated a strong priming effect of tDCS on rTMSinduced excitability changes in M1. PTs were determined with single-pulse TMS before and immediately after tDCS and twice after rTMS. RESULTS. Anodal tDCS led to a transient decrease in PT, and subsequent 5 Hz rTMS induced an earlier return of the PT back to baseline. Cathodal tDCS produced a short-lasting increase in PT, but 5 Hz rTMS did not influence the tDCS-induced increase in PT. In a control experiment on four subjects, a 20-second train of occipital 5 Hz rTMS left the PT unchanged, whereas a 60-second train produced a similar decrease in PT as anodal tDCS alone. CONCLUSIONS. Compared with previous work on the M1, tDCS and rTMS of the visual cortex only produce short-lasting changes in cortical excitability. Moreover, the priming effects of tDCS on subsequent rTMS conditioning are relatively modest. These discrepancies point to substantial differences in the modifiability of human motor and visual cortex."],["dc.identifier.doi","10.1167/iovs.07-0706"],["dc.identifier.isi","000251450800055"],["dc.identifier.pmid","18055832"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48190"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Assoc Research Vision Ophthalmology Inc"],["dc.relation.issn","0146-0404"],["dc.title","Bidirectional modulation of primary visual cortex excitability: A combined tDCS and rTMS study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1802"],["dc.bibliographiccitation.issue","13"],["dc.bibliographiccitation.journal","Neuropsychologia"],["dc.bibliographiccitation.lastpage","1807"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Kincses, T. Z."],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:42:45Z"],["dc.date.available","2018-11-07T10:42:45Z"],["dc.date.issued","2003"],["dc.description.abstract","Small moving sensations, so-called moving phosphenes are perceived, when V5, a visual area important for visual motion analysis, is stimulated by transcranial magnetic stimulation (TMS). However, it is still a matter of debate if only V5 takes part in movement perception or other visual areas are also involved in this process. In this study we tested the involvement of V I in the perception of moving phosphenes by applying transcranial direct current stimulation (tDCS) to this area. tDCS is a non-invasive stimulation technique known to modulate cortical excitability in a polarity-specific manner. Moving and stationary phosphene thresholds (PT) were measured by TMS before, immediately after and 10, 20 and 30 min after the end of 10 min cathodal and anodal tDCS in nine healthy subjects. Reduced PTs were detected immediately and 10 min after the end of anodal tDCS while cathodal stimulation resulted in an opposite effect. Our results show that the excitability shifts induced by V I stimulation can modulate moving phosphene perception. tDCS elicits transient, but yet reversible effects, thus presenting a promising tool for neuroplasticity research. (C) 2003 Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/S0028-3932(03)00181-7"],["dc.identifier.isi","000186215700009"],["dc.identifier.pmid","14527543"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46878"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0028-3932"],["dc.title","Modulation of moving phosphene thresholds by transcranial direct current stimulation of V1 in human"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3109"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal of Neurophysiology"],["dc.bibliographiccitation.lastpage","3117"],["dc.bibliographiccitation.volume","97"],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Doemkes, S."],["dc.contributor.author","Karakose, T."],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Liebetanz, David"],["dc.contributor.author","Lang, N."],["dc.contributor.author","Tergau, Frithjof"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T11:03:39Z"],["dc.date.available","2018-11-07T11:03:39Z"],["dc.date.issued","2007"],["dc.description.abstract","Transcranial DC stimulation (tDCS) induces stimulation polarity-dependent neuroplastic excitability shifts in the human brain. Because it accomplishes long-lasting effects and its application is simple, it is used increasingly. However, one drawback is its low focality, caused by 1) the large stimulation electrode and 2) the functionally effective reference electrode, which is also situated on the scalp. We aimed to increase the focality of tDCS, which might improve the interpretation of the functional effects of stimulation because it will restrict its effects to more clearly defined cortical areas. Moreover, it will avoid unwanted reversed effects of tDCS under the reference electrode, which is of special importance in clinical settings, when a homogeneous shift of cortical excitability is needed. Because current density (current strength/electrode size) determines the efficacy of tDCS, increased focality should be accomplished by 1) reducing stimulation electrode size, but keeping current density constant; or 2) increasing reference electrode size under constant current strength. We tested these hypotheses for motor cortex tDCS. The results show that reducing the size of the motor cortex DC-stimulation electrode focalized the respective tDCS-induced excitability changes. Increasing the size of the frontopolar reference electrode rendered stimulation over this cortex functionally inefficient, but did not compromise the tDCS-generated motor cortical excitability shifts. Thus tDCS-generated modulations of cortical excitability can be focused by reducing the size of the stimulation electrode and by increasing the size of the reference electrode. For future applications of tDCS, such paradigms may help to achieve more selective tDCS effects."],["dc.identifier.doi","10.1152/jn.01312.2006"],["dc.identifier.isi","000247929900048"],["dc.identifier.pmid","17251360"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51664"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Physiological Soc"],["dc.relation.issn","0022-3077"],["dc.title","Shaping the effects of transcranial direct current stimulation of the human motor cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","788"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Cephalalgia"],["dc.bibliographiccitation.lastpage","794"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Temme, Johanna"],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Varga, Edina T."],["dc.contributor.author","Lang, N."],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:55:11Z"],["dc.date.available","2018-11-07T10:55:11Z"],["dc.date.issued","2005"],["dc.description.abstract","Much research on visual functions in migraine has pinpointed the existence of abnormal visual processing between attacks. However, it is not clear if this is due to cortical hyper- or hypoexcitability. We aimed to clarify this issue by comparing motion perception thresholds of subjects with migraine with (MA) or without aura (MoA) and control subjects. Two types of dot kinetograms were used: in the first experiment coherently moving dots were presented in an incoherent environment, while in the second only coherent motion was seen. Subjects with migraine displayed significantly impaired motion perception compared with controls when they had to detect the direction of the coherently moving dots in an incoherent environment, while they were slightly better in a direction discrimination task, where only coherent motion was presented. This pattern of results is comparable to those achieved by an external excitability enhancement of V5 induced in healthy human subjects in a former study of our group. According to this, a cortical excitability enhancement can result in an impaired focusing on a given signal against a noisy background, but improves perception of non-ambiguous stimuli. Thus we conclude that migraineurs display enhanced visual cortical excitability between attacks in V5."],["dc.identifier.doi","10.1111/j.1468-2982.2005.00949.x"],["dc.identifier.isi","000231902500004"],["dc.identifier.pmid","16162255"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49728"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0333-1024"],["dc.title","Altered motion perception in migraineurs: evidence for interictal cortical hyperexcitability"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","206"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","223"],["dc.bibliographiccitation.volume","1"],["dc.contributor.author","Nitsche, Michael A."],["dc.contributor.author","Cohen, Leonardo G."],["dc.contributor.author","Wassermann, Eric M."],["dc.contributor.author","Priori, Alberto"],["dc.contributor.author","Lang, Nicolas"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Hummel, Friedhelm C."],["dc.contributor.author","Boggio, Paulo Sergio"],["dc.contributor.author","Fregni, Felipe"],["dc.contributor.author","Pascual-Leone, Alvaro"],["dc.date.accessioned","2018-11-07T11:13:16Z"],["dc.date.available","2018-11-07T11:13:16Z"],["dc.date.issued","2008"],["dc.description.abstract","Effects of weak electrical currents oil brain and neuronal function were first described decades ago. Recently. DC polarization of the brain was reintroduced as a noninvasive technique to alter cortical activity in humans. Beyond this, transcranial direct current stimulation (tDCS) of different cortical areas has been shown, ill various Studies. to result in modifications of perceptual. cognitive, and behavioral functions. Moreover, preliminary data suggest that it can induce beneficial effects in brain disorders. Brain stimulation with weak direct Currents is a promising tool in human neuroscience and neurobehavioral research. To facilitate and standardize future tDCS Studies, we offer this overview of the state of the art for tDCS. (c) 2008 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.brs.2008.06.004"],["dc.identifier.isi","000262716800008"],["dc.identifier.pmid","20633386"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53850"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1935-861X"],["dc.title","Transcranial direct current stimulation: State of the art 2008"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of the Neurological Sciences"],["dc.bibliographiccitation.volume","238"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Begemeier, S."],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:54:19Z"],["dc.date.available","2018-11-07T10:54:19Z"],["dc.date.issued","2005"],["dc.format.extent","S520"],["dc.identifier.isi","000235088004401"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49537"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.publisher.place","Amsterdam"],["dc.relation.conference","18th World Congress of Neurology"],["dc.relation.eventlocation","Sydney, AUSTRALIA"],["dc.relation.issn","0022-510X"],["dc.title","Homeostatic plasticity after inhibition of the cortex adds to the repertoire for facilitating motor learning"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","23"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Experimental Brain Research"],["dc.bibliographiccitation.lastpage","30"],["dc.bibliographiccitation.volume","166"],["dc.contributor.author","Fregni, Felipe"],["dc.contributor.author","Boggio, Paulo Sergio"],["dc.contributor.author","Nitsche, M."],["dc.contributor.author","Bermpohl, F."],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Feredoes, E."],["dc.contributor.author","Marcolin, M. A."],["dc.contributor.author","Rigonatti, Sergio P."],["dc.contributor.author","Silva, M. Teresa A."],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Pascual-Leone, Alvaro"],["dc.date.accessioned","2018-11-07T10:56:08Z"],["dc.date.available","2018-11-07T10:56:08Z"],["dc.date.issued","2005"],["dc.description.abstract","Previous studies have claimed that weak transcranial direct current stimulation (tDCS) induces persisting excitability changes in the human motor cortex that can be more pronounced than cortical modulation induced by transcranial magnetic stimulation, but there are no studies that have evaluated the effects of tDCS on working memory. Our aim was to determine whether anodal transcranial direct current stimulation, which enhances brain cortical excitability and activity, would modify performance in a sequential-letter working memory task when administered to the dorsolateral prefrontal cortex (DLPFC). Fifteen subjects underwent a three-back working memory task based on letters. This task was performed during sham and anodal stimulation applied over the left DLPFC. Moreover seven of these subjects performed the same task, but with inverse polarity (cathodal stimulation of the left DLPFC) and anodal stimulation of the primary motor cortex (M1). Our results indicate that only anodal stimulation of the left prefrontal cortex, but not cathodal stimulation of left DLPFC or anodal stimulation of M1, increases the accuracy of the task performance when compared to sham stimulation of the same area. This accuracy enhancement during active stimulation cannot be accounted for by slowed responses, as response times were not changed by stimulation. Our results indicate that left prefrontal anodal stimulation leads to an enhancement of working memory performance. Furthermore, this effect depends on the stimulation polarity and is specific to the site of stimulation. This result may be helpful to develop future interventions aiming at clinical benefits."],["dc.description.sponsorship","NCRR NIH HHS [K24 RR018875]; NHLBI NIH HHS [K30 HL04095-03]"],["dc.identifier.doi","10.1007/s00221-005-2334-6"],["dc.identifier.isi","000232616900003"],["dc.identifier.pmid","15999258"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49942"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0014-4819"],["dc.title","Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]