Thurow, Corinna

[["dc.bibliographiccitation.journal","BMC Plant Biology"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Huang, Li-Jun"],["dc.contributor.author","Li, Ning"],["dc.contributor.author","Thurow, Corinna"],["dc.contributor.author","Wirtz, Markus"],["dc.contributor.author","Hell, Ruediger"],["dc.contributor.author","Gatz, Christiane"],["dc.date.accessioned","2018-11-07T10:08:35Z"],["dc.date.available","2018-11-07T10:08:35Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: Glutaredoxins (GRXs) are small proteins which bind glutathione to either reduce disulfide bonds or to coordinate iron sulfur clusters. Whereas these well-established functions are associated with ubiquitously occurring GRXs that encode variants of a CPYC or a CGFS motif in the active center, land plants also possess CCxC/S-type GRXs (named ROXYs) for which the biochemical functions are yet unknown. ROXYs physically and genetically interact with bZIP transcription factors of the TGA family. In Arabidopsis, ectopically expressed ROXY19 (originally named GRX480 or GRXC9) negatively regulates expression of jasmonic acid/ethylene-induced defense genes through an unknown mechanism that requires at least one of the redundant transcription factors TGA2, TGA5 or TGA6. Results: Ectopically expressed ROXY19 interferes with the activation of TGA-dependent detoxification genes. Similar to the tga2 tga5 tga6 mutant, 35S: ROXY19 plants are more susceptible to the harmful chemical TIBA (2,3,5-triiodobenzoic acid). The repressive function of ROXY19 depends on the integrity of the active site, which can be either CCMC or CPYC but not SSMS. Ectopic expression of the related GRX ROXY18/GRXS13 also led to increased susceptibility to TIBA, indicating potential functional redundancy of members of the ROXY gene family. This redundancy might explain why roxy19 knock-out plants did not show a phenotype with respect to the regulation of the TIBA-induced detoxification program. Complementation of the tga2 tga5 tga6 mutant with either TGA5 or TGA5(C186S), in which the single potential target-site of ROXY19 had been eliminated, did not reveal any evidence for a critical redox modification that might be important for controlling the detoxification program. Conclusions: ROXY19 and related proteins of the ROXY gene family can function as negative regulators of TGA-dependent promoters controlling detoxification genes."],["dc.description.sponsorship","University of Gottingen; German Research Foundation [SPP1710]"],["dc.identifier.doi","10.1186/s12870-016-0886-1"],["dc.identifier.isi","000382908800001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13883"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39488"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1471-2229"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Ectopically expressed glutaredoxin ROXY19 negatively regulates the detoxification pathway in Arabidopsis thaliana"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1635"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Plants"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Thurow, Corinna"],["dc.contributor.author","Krischke, Markus"],["dc.contributor.author","Mueller, Martin J."],["dc.contributor.author","Gatz, Christiane"],["dc.date.accessioned","2021-04-14T08:23:10Z"],["dc.date.available","2021-04-14T08:23:10Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.3390/plants9121635"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80818"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.publisher","MDPI"],["dc.relation.eissn","2223-7747"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Induction of Jasmonoyl-Isoleucine (JA-Ile)-Dependent JASMONATE ZIM-DOMAIN (JAZ) Genes in NaCl-Treated Arabidopsis thaliana Roots Can Occur at Very Low JA-Ile Levels and in the Absence of the JA/JA-Ile Transporter JAT1/AtABCG16"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","775"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","NUCLEIC ACIDS RESEARCH"],["dc.bibliographiccitation.lastpage","781"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Krawczyk, Stefanie"],["dc.contributor.author","Thurow, Corinna"],["dc.contributor.author","Niggeweg, Ricarda"],["dc.contributor.author","Gatz, Christiane"],["dc.date.accessioned","2019-07-10T08:12:50Z"],["dc.date.available","2019-07-10T08:12:50Z"],["dc.date.issued","2002"],["dc.description.abstract","In higher plants, activation sequence-1 (as-1) of the cauliflower mosaic virus 35S promoter mediates both salicylic acid- and auxin-inducible transcriptional activation. Originally found in viral and T-DNA promoters, as-1-like elements are also functional elements of plant promoters activated in the course of a defence response upon pathogen attack. as-1-like elements are characterised by two imperfect palindromes with the palindromic centres being spaced by 12 bp. They are recognised by plant nuclear as-1-binding factor ASF-1, the major component of which is basic/leucine zipper (bZIP) protein TGA2.2 (~80%) in Nicotiana tabacum. In electrophoretic mobility shift assays, ASF-1 as well as bZIP proteins TGA2.2, TGA2.1 and TGA1a showed a 3–10-fold reduced binding affinity to mutant as-1 elements encoding insertions of 2, 4, 6, 8 or 10 bp between the palindromes, respectively. This correlated with a 5–10-fold reduction in transcriptional activation from these elements in transient expression assays. Although ASF-1 and TGA factors bound efficiently to a mutant element carrying a 2 bp deletion between the palindromes [as-1/(–2)], the latter was strongly compromised with respect to mediating gene expression in vivo. A fusion protein consisting of TGA2.2 and a constitutive activation domain mediated transactivation from as-1/(–2) demonstrating binding of TGA factors in vivo. We therefore conclude that both DNA binding and transactivation require optimal positioning of TGA factors on the as-1 element."],["dc.identifier.fs","28444"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/4102"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/61055"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","0305-1048"],["dc.relation.issn","1362-4962"],["dc.relation.orgunit","Fakultät für Biologie und Psychologie"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","570"],["dc.title","Analysis of the spacing between the two palindromes of activation sequence-1 with respect to binding to different TGA factors and transcriptional activation potential."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e239"],["dc.bibliographiccitation.journal","PeerJ"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Landesfeind, Manuel"],["dc.contributor.author","Kaever, Alexander"],["dc.contributor.author","Feussner, Kirstin"],["dc.contributor.author","Thurow, Corinna"],["dc.contributor.author","Gatz, Christiane"],["dc.contributor.author","Feussner, Ivo"],["dc.contributor.author","Meinicke, Peter"],["dc.date.accessioned","2018-11-07T09:42:35Z"],["dc.date.available","2018-11-07T09:42:35Z"],["dc.date.issued","2014"],["dc.description.abstract","State of the art high-throughput technologies allow comprehensive experimental studies of organism metabolism and induce the need for a convenient presentation of large heterogeneous datasets. Especially, the combined analysis and visualization of data from different high-throughput technologies remains a key challenge in bioinformatics. We present here the MarVis-Graph software for integrative analysis of metabolic and transcriptomic data. All experimental data is investigated in terms of the full metabolic network obtained from a reference database. The reactions of the network are scored based on the associated data, and sub-networks, according to connected high-scoring reactions, are identified. Finally, MarVis-Graph scores the detected sub-networks, evaluates them by means of a random permutation test and presents them as a ranked list. Furthermore, MarVis-Graph features an interactive network visualization that provides researchers with a convenient view on the results. The key advantage of MarVis-Graph is the analysis of reactions detached from their pathways so that it is possible to identify new pathways or to connect known pathways by previously unrelated reactions. The MarVis-Graph software is freely available for academic use and can be downloaded at: http://marvis.gobics.de/marvis-graph."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2014"],["dc.identifier.doi","10.7717/peerj.239"],["dc.identifier.isi","000347564400001"],["dc.identifier.pmid","24688832"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10012"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33990"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Peerj Inc"],["dc.relation.issn","2167-8359"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Integrative study of Arabidopsis thaliana metabolomic and transcriptomic data with the interactive MarVis-Graph software"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1532"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Cells"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Li, Ning"],["dc.contributor.author","Uhrig, Joachim F."],["dc.contributor.author","Thurow, Corinna"],["dc.contributor.author","Huang, Li-Jun"],["dc.contributor.author","Gatz, Christiane"],["dc.date.accessioned","2020-12-10T18:46:59Z"],["dc.date.available","2020-12-10T18:46:59Z"],["dc.date.issued","2019"],["dc.description.sponsorship","the National Natural Science Foundation of China"],["dc.identifier.doi","10.3390/cells8121532"],["dc.identifier.eissn","2073-4409"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78605"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","MDPI"],["dc.relation.eissn","2073-4409"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Reconstitution of the Jasmonate Signaling Pathway in Plant Protoplasts"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","tpj.15372"],["dc.bibliographiccitation.firstpage","1119"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","The Plant Journal"],["dc.bibliographiccitation.lastpage","1130"],["dc.bibliographiccitation.volume","107"],["dc.contributor.affiliation","Ulrich, Louisa; 1Department of Plant Molecular Biology and Physiology Albrecht‐von‐Haller‐Institute for Plant Sciences University of Göttingen Göttingen Germany"],["dc.contributor.affiliation","Schmitz, Johanna; 1Department of Plant Molecular Biology and Physiology Albrecht‐von‐Haller‐Institute for Plant Sciences University of Göttingen Göttingen Germany"],["dc.contributor.affiliation","Thurow, Corinna; 1Department of Plant Molecular Biology and Physiology Albrecht‐von‐Haller‐Institute for Plant Sciences University of Göttingen Göttingen Germany"],["dc.contributor.author","Ulrich, Louisa"],["dc.contributor.author","Schmitz, Johanna"],["dc.contributor.author","Thurow, Corinna"],["dc.contributor.author","Gatz, Christiane"],["dc.date.accessioned","2021-08-12T07:45:27Z"],["dc.date.available","2021-08-12T07:45:27Z"],["dc.date.issued","2021"],["dc.date.updated","2022-03-21T05:07:10Z"],["dc.description.abstract","Summary The F‐box protein CORONANTINE INSENSITIVE1 (COI1) serves as the receptor for the plant hormone jasmonoyl‐isoleucine (JA‐Ile). COI1, its co‐receptors of the JASMONATE ZIM‐domain (JAZ) protein family, and JA‐Ile form a functional unit that regulates growth or defense mechanisms in response to various stress cues. Strikingly, COI1, but not JA‐Ile, is required for susceptibility of Arabidopsis thaliana towards the soil‐borne vascular pathogen Verticillium longisporum. In order to obtain marker genes for further analysis of this JA‐Ile‐independent COI1 function, transcriptome analysis of roots of coi1 and allene oxide synthase (aos) plants (impaired in JA biosynthesis) was performed. Intriguingly, nearly all of the genes that are differentially expressed in coi1 versus aos and wild type are constitutively more highly expressed in coi1. To support our notion that COI1 acts independently of its known downstream signaling components, coi1 plants were complemented with a COI1 variant (COI1AA) that is compromised in its interaction with JAZs. As expected, these plants showed only weak induction of the expression of the JA‐Ile marker gene VEGETATIVE STORAGE PROTEIN2 after wounding and remained sterile. On the other hand, genes affected by COI1 but not by JA‐Ile were still strongly repressed by COI1AA. We suggest that COI1 has a potential moonlighting function that serves to repress gene expression in a JA‐Ile‐ and JAZ‐independent manner."],["dc.description.abstract","Significance Statement Phenotypic differences of hormone receptor and corresponding hormone biosynthesis mutants are unexpected. Such an unusual scenario was discovered for COI1, which affects the root transcriptome even when disconnected from its signaling pathway. image"],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft"],["dc.identifier.doi","10.1111/tpj.15372"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88468"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation.eissn","1365-313X"],["dc.relation.issn","0960-7412"],["dc.rights","This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made."],["dc.title","The jasmonoyl‐isoleucine receptor CORONATINE INSENSITIVE1 suppresses defense gene expression in Arabidopsis roots independently of its ligand"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]