Raaz, Uwe

[["dc.bibliographiccitation.journal","Frontiers in Physiology"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Wagenhäuser, Markus U."],["dc.contributor.author","Schellinger, Isabel N."],["dc.contributor.author","Yoshino, Takuya"],["dc.contributor.author","Toyama, Kensuke"],["dc.contributor.author","Kayama, Yosuke"],["dc.contributor.author","Deng, Alicia"],["dc.contributor.author","Guenther, Sabina P."],["dc.contributor.author","Petzold, Anne"],["dc.contributor.author","Mulorz, Joscha"],["dc.contributor.author","Mulorz, Pireyatharsheny"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Ibing, Wiebke"],["dc.contributor.author","Elvers, Margitta"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Ramasubramanian, Anand K."],["dc.contributor.author","Adam, Matti"],["dc.contributor.author","Schelzig, Hubert"],["dc.contributor.author","Spin, Joshua M."],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Tsao, Philip S."],["dc.date.accessioned","2020-12-10T18:44:37Z"],["dc.date.available","2020-12-10T18:44:37Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3389/fphys.2018.01459"],["dc.identifier.eissn","1664-042X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78531"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Chronic Nicotine Exposure Induces Murine Aortic Remodeling and Stiffness Segmentation—Implications for Abdominal Aortic Aneurysm Susceptibility"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e0202146"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Stiermaier, Thomas"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Chiribiri, Amedeo"],["dc.contributor.author","Möller, Christian"],["dc.contributor.author","Graf, Tobias"],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Villa, Adriana"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Thiele, Holger"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Eitel, Ingo"],["dc.contributor.editor","Novo, Giuseppina"],["dc.date.accessioned","2020-12-10T18:42:08Z"],["dc.date.available","2020-12-10T18:42:08Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1371/journal.pone.0202146"],["dc.identifier.eissn","1932-6203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15691"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77819"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Right ventricular strain assessment by cardiovascular magnetic resonance myocardial feature tracking allows optimized risk stratification in Takotsubo syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Circulation"],["dc.contributor.author","Backhaus, Sören J"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","George, Elisabeth F"],["dc.contributor.author","Hellenkamp, Kristian"],["dc.contributor.author","Gertz, Roman J"],["dc.contributor.author","Billing, Marcus"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Hasenfuß, Gerd P."],["dc.contributor.author","Seidler, Tim"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2021-03-08T07:13:50Z"],["dc.date.available","2021-03-08T07:13:50Z"],["dc.date.issued","2021-01-21"],["dc.description.abstract","Background: Right heart catheterisation (RHC) using exercise-stress is the reference standard for the diagnosis of heart failure with preserved ejection fraction (HFpEF) but carries the risk of the invasive procedure. We hypothesized that real-time cardiovascular magnetic resonance (RT-CMR) exercise imaging with pathophysiologic data at excellent temporal and spatial resolution may represent a contemporary non-invasive alternative for diagnosing HFpEF. Methods: The HFpEF stress trial (DZHK-17, NCT03260621) prospectively recruited 75 patients with echocardiographic signs of diastolic dysfunction and dyspnea on exertion (E/e'>8, New York Heart Association (NYHA) class ≥II) to undergo echocardiography, RHC and RT-CMR at rest and during exercise-stress. HFpEF was defined according to pulmonary capillary wedge pressure (PCWP ≥15mmHg at rest or ≥25mmHg during exercise stress). RT-CMR functional assessments included time-volume curves for total and early (1/3) diastolic left ventricular (LV) filling, left atrial (LA) emptying and LV/LA long axis strain (LAS). Results: HFpEF patients (n=34, median PCWP rest 13mmHg, stress 27mmHg) had higher E/e' (12.5 vs. 9.15), NT-proBNP (255 vs. 75ng/l) and LA volume index (43.8 vs. 36.2ml/m2) compared to non-cardiac dyspnea patients (n=34, rest 8mmHg, stress 18mmHg, p≤0.001 for all). Seven patients were excluded due to the presence of non HFpEF cardiac disease causing dyspnea on imaging. There were no differences in RT-CMR LV total and early diastolic filling at rest and during exercise-stress (p≥0.164) between HFpEF and non-cardiac dyspnea. RT-CMR revealed significantly impaired LA total and early (p<0.001) diastolic emptying in HFpEF during exercise-stress. RT-CMR exercise-stress LA LAS was independently associated with HFpEF (adjusted odds ratio 0.657, 95% confidence interval [0.516; 0.838], p=0.001) after adjustment for clinical and imaging parameters and emerged as the best predictor for HFpEF (area under the curve rest 0.82 vs. exercise-stress 0.93, p=0.029). Conclusions: RT-CMR allows highly accurate identification of HFpEF during physiological exercise and qualifies as a suitable non-invasive diagnostic alternative. These results will need to be confirmed in multi-centre prospective research studies to establish widespread routine clinical use. Clinical Trial Registration: URL: https://www.clinicaltrials.gov Unique Identifier: NCT03260621."],["dc.identifier.doi","10.1161/CIRCULATIONAHA.120.051542"],["dc.identifier.pmid","33472397"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80476"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/302"],["dc.language.iso","en"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation.issn","0009-7322"],["dc.relation.issn","1524-4539"],["dc.relation.workinggroup","RG Hasenfuß"],["dc.relation.workinggroup","RG Uecker"],["dc.title","Exercise-Stress Real-time Cardiac Magnetic Resonance Imaging for Non-Invasive Characterisation of Heart Failure with Preserved Ejection Fraction: The HFpEF Stress Trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","256"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","262"],["dc.bibliographiccitation.volume","273"],["dc.contributor.author","Backhaus, Sören J."],["dc.contributor.author","Stiermaier, Thomas"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Chiribiri, Amedeo"],["dc.contributor.author","Lamata, Pablo"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Villa, Adriana"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Thiele, Holger"],["dc.contributor.author","Eitel, Ingo"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2020-12-10T14:24:32Z"],["dc.date.available","2020-12-10T14:24:32Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.ijcard.2018.04.088"],["dc.identifier.issn","0167-5273"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72283"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Temporal changes within mechanical dyssynchrony and rotational mechanics in Takotsubo syndrome: A cardiovascular magnetic resonance imaging study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","943"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","JACC: Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","945"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Backhaus, Sören J."],["dc.contributor.author","Rösel, Simon F."],["dc.contributor.author","Schulz, Alexander"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Hellenkamp, Kristian"],["dc.contributor.author","Gertz, Roman J."],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2022-07-01T07:35:48Z"],["dc.date.available","2022-07-01T07:35:48Z"],["dc.date.issued","2022"],["dc.description.sponsorship"," http://dx.doi.org/10.13039/100010447 Deutsches Zentrum für Herz-Kreislaufforschung"],["dc.identifier.doi","10.1016/j.jcmg.2021.11.013"],["dc.identifier.pii","S1936878X21008421"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112270"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.issn","1936-878X"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","RT-CMR Imaging for Noninvasive Characterization of HFpEF"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","5160"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","5170"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Stiermaier, Thomas"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Chiribiri, Amedeo"],["dc.contributor.author","Möller, Christian"],["dc.contributor.author","Graf, Tobias"],["dc.contributor.author","Villnow, Christina"],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Villa, Adriana"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Thiele, Holger"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Eitel, Ingo"],["dc.date.accessioned","2020-12-10T14:10:12Z"],["dc.date.available","2020-12-10T14:10:12Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1007/s00330-018-5475-2"],["dc.identifier.eissn","1432-1084"],["dc.identifier.issn","0938-7994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70674"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Left ventricular myocardial deformation in Takotsubo syndrome: a cardiovascular magnetic resonance myocardial feature tracking study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Journal of the American College of Cardiology"],["dc.bibliographiccitation.volume","69"],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Schellinger, Isabel N."],["dc.contributor.author","Mattern, Karin"],["dc.contributor.author","Mattes, Lena"],["dc.contributor.author","Spin, Joshua"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Maegdefessel, Lars"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Tsao, Philip S."],["dc.date.accessioned","2018-11-07T10:26:06Z"],["dc.date.available","2018-11-07T10:26:06Z"],["dc.date.issued","2017"],["dc.format.extent","2023"],["dc.identifier.isi","000397342302745"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42971"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Science Inc"],["dc.publisher.place","New york"],["dc.relation.conference","66th Annual Scientific Session and Expo of the American-College-of-Cardiology (ACC)"],["dc.relation.eventlocation","Washington, DC"],["dc.relation.issn","1558-3597"],["dc.relation.issn","0735-1097"],["dc.title","NON-CODING RNAS COMPREHENSIVELY COUNTERACT ADVERSE ARTERIAL REMODELING AND STIFFENING IN TYPE 2 DIABETES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]