Slotta, Jan Erik

[["dc.bibliographiccitation.firstpage","589"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Surgery"],["dc.bibliographiccitation.lastpage","595"],["dc.bibliographiccitation.volume","154"],["dc.contributor.author","Justinger, Christoph"],["dc.contributor.author","Slotta, Jan Erik"],["dc.contributor.author","Ningel, Sebastian"],["dc.contributor.author","Graeber, Stefan"],["dc.contributor.author","Kollmar, Otto"],["dc.contributor.author","Schilling, Martin Karl"],["dc.date.accessioned","2018-11-07T09:20:40Z"],["dc.date.available","2018-11-07T09:20:40Z"],["dc.date.issued","2013"],["dc.description.abstract","Background. Wound infections after abdominal surgery are still frequent types of nosocomial infections. Suture materials might serve as a vehicle for mechanical transport of bacteria into the surgical wound. To prevent the contamination of suture material in surgical wounds, triclosan-coated suture materials with antibacterial activity was developed. We here report a prospective randomized pathway controlled trial investigating the effect of triclosan impregnation of polydioxanone sutures used for abdominal wall closure on the rate of surgical-site infections. Patients and methods. A total of 856 patients included in this trial underwent a standardized clinical pathway documented abdominal wall closure after abdominal surgery. Patients were randomized to have the fascia closed with either a 2-0 polydioxanone loop or a triclosan impregnated 2-0 polydioxanone loop. The primary outcome was the number of wound infections. Risk factors for poor wound healing were collected prospectively to compare the two groups. Results. When a PDS loop suture for abdominal wall closure was used, 42 (11.3%) patients with wound infections were detected. The number of patients with wound infections decreased significantly to 31 when the PDS plus for abdominal wall closure was used (6.4%, P < .05). Other risk factors for the development of side infections were comparably in the two groups. Conclusion. This clinical pathway facilitated trial shows that triclosan impregnation of a 2-0 polydioxanone closing suture can decrease wound infections in patients having a laparotomy for general and abdominal vascular procedures."],["dc.description.sponsorship","Johnson&Johnson, Summerville, NJ"],["dc.identifier.doi","10.1016/j.surg.2013.04.011"],["dc.identifier.isi","000324085900021"],["dc.identifier.pmid","23859304"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11334"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28931"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Mosby-elsevier"],["dc.relation.issn","0039-6060"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Surgical-site infection after abdominal wall closure with triclosan-impregnated polydioxanone sutures: Results of a randomized clinical pathway facilitated trial (NCT00998907)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]