Hertel, Dietrich

[["dc.bibliographiccitation.firstpage","9605"],["dc.bibliographiccitation.issue","24"],["dc.bibliographiccitation.journal","Journal of Biological Chemistry"],["dc.bibliographiccitation.lastpage","9614"],["dc.bibliographiccitation.volume","294"],["dc.contributor.author","Gundlach, Jan"],["dc.contributor.author","Krüger, Larissa"],["dc.contributor.author","Herzberg, Christina"],["dc.contributor.author","Turdiev, Asan"],["dc.contributor.author","Poehlein, Anja"],["dc.contributor.author","Tascón, Igor"],["dc.contributor.author","Weiss, Martin"],["dc.contributor.author","Hertel, Dietrich"],["dc.contributor.author","Daniel, Rolf"],["dc.contributor.author","Hänelt, Inga"],["dc.contributor.author","Lee, Vincent T."],["dc.contributor.author","Stülke, Jörg"],["dc.date.accessioned","2020-12-10T18:12:59Z"],["dc.date.available","2020-12-10T18:12:59Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1074/jbc.RA119.008774"],["dc.identifier.eissn","1083-351X"],["dc.identifier.issn","0021-9258"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74548"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Sustained sensing in potassium homeostasis: Cyclic di-AMP controls potassium uptake by KimA at the levels of expression and activity"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","mBio"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Gundlach, Jan"],["dc.contributor.author","Herzberg, Christina"],["dc.contributor.author","Hertel, Dietrich"],["dc.contributor.author","Thürmer, Andrea"],["dc.contributor.author","Daniel, Rolf"],["dc.contributor.author","Link, Hannes"],["dc.contributor.author","Stülke, Jörg"],["dc.contributor.editor","Brennan, Richard Gerald"],["dc.date.accessioned","2020-12-10T18:37:03Z"],["dc.date.available","2020-12-10T18:37:03Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1128/mBio.00861-17"],["dc.identifier.eissn","2150-7511"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76827"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Adaptation of Bacillus subtilis to Life at Extreme Potassium Limitation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","eaal3011"],["dc.bibliographiccitation.issue","475"],["dc.bibliographiccitation.journal","Science Signaling"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Gundlach, Jan"],["dc.contributor.author","Herzberg, Christina"],["dc.contributor.author","Kaever, Volkhard"],["dc.contributor.author","Gunka, Katrin"],["dc.contributor.author","Hoffmann, Tamara"],["dc.contributor.author","Weiss, Martin"],["dc.contributor.author","Gibhardt, Johannes"],["dc.contributor.author","Thuermer, Andrea"],["dc.contributor.author","Hertel, Dietrich"],["dc.contributor.author","Daniel, Rolf"],["dc.contributor.author","Bremer, Erhard"],["dc.contributor.author","Commichau, Fabian M."],["dc.contributor.author","Stulke, Joerg"],["dc.date.accessioned","2018-11-07T10:24:56Z"],["dc.date.available","2018-11-07T10:24:56Z"],["dc.date.issued","2017"],["dc.description.abstract","The second messenger cyclic di-adenosine monophosphate (c-di-AMP) is essential in the Gram-positive model organism Bacillus subtilis and in related pathogenic bacteria. It controls the activity of the conserved ydaO riboswitch and of several proteins involved in potassium (K+) uptake. We found that the YdaO protein was conserved among several different bacteria and provide evidence that YdaO functions as a K+ transporter. Thus, we renamed the gene and protein KimA (K+ importer A). Reporter activity assays indicated that expression beyond the c-di-AMP-responsive riboswitch of the kimA upstream regulatory region occurred only in bacteria grown in medium containing low K+ concentrations. Furthermore, mass spectrometry analysis indicated that c-di-AMP accumulated in bacteria grown in the presence of high K+ concentrations but not in low concentrations. A bacterial strain lacking all genes encoding c-di-AMP-synthesizing enzymes was viable when grown in medium containing low K+ concentrations, but not at higher K+ concentrations unless it acquired suppressor mutations in the gene encoding the cation exporter NhaK. Thus, our results indicated that the control of potassium homeostasis is an essential function of c-di-AMP."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft [SPP1879]"],["dc.identifier.doi","10.1126/scisignal.aal3011"],["dc.identifier.isi","000400128400003"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42751"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Amer Assoc Advancement Science"],["dc.relation.issn","1937-9145"],["dc.relation.issn","1945-0877"],["dc.title","Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]