Hasenfuß, Gerd P.

[["dc.bibliographiccitation.firstpage","87"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","92"],["dc.bibliographiccitation.volume","300"],["dc.contributor.author","Kalbacher, Daniel"],["dc.contributor.author","Daubmann, Anne"],["dc.contributor.author","Tigges, Eike"],["dc.contributor.author","Hünlich, Marc"],["dc.contributor.author","Wiese, Sabrina"],["dc.contributor.author","Conradi, Lenard"],["dc.contributor.author","Schirmer, Johannes"],["dc.contributor.author","Beuthner, Bo Eric"],["dc.contributor.author","Reichenspurner, Hermann"],["dc.contributor.author","Wegscheider, Karl"],["dc.contributor.author","Danner, Bernhard C."],["dc.contributor.author","Tichelbäcker, Tobias"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schäfer, Ulrich"],["dc.contributor.author","Blankenberg, Stefan"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Schillinger, Wolfang"],["dc.contributor.author","Lubos, Edith"],["dc.date.accessioned","2021-04-14T08:27:38Z"],["dc.date.available","2021-04-14T08:27:38Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.ijcard.2019.09.027"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82358"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","0167-5273"],["dc.title","Impact of pre- and post-procedural renal dysfunction on long-term outcomes in patients undergoing MitraClip implantation: A retrospective analysis from two German high-volume centres"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Journal of Interventional Cardiology"],["dc.bibliographiccitation.lastpage","9"],["dc.bibliographiccitation.volume","2022"],["dc.contributor.author","Evertz, Ruben"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Backhaus, Sören J."],["dc.contributor.author","Schulz, Alexander"],["dc.contributor.author","Beuthner, Bo Eric"],["dc.contributor.author","Topci, Rodi"],["dc.contributor.author","Toischer, Karl"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.editor","Kim, Michael C."],["dc.date.accessioned","2022-06-01T09:39:37Z"],["dc.date.available","2022-06-01T09:39:37Z"],["dc.date.issued","2022"],["dc.description.abstract","Background. Cardiovascular magnetic resonance imaging is considered the reference standard for assessing cardiac morphology and function and has demonstrated prognostic utility in patients undergoing transcatheter aortic valve replacement (TAVR). Novel fully automated analyses may facilitate data analyses but have not yet been compared against conventional manual data acquisition in patients with severe aortic stenosis (AS). Methods. Fully automated and manual biventricular assessments were performed in 139 AS patients scheduled for TAVR using commercially available software (suiteHEART®, Neosoft; QMass®, Medis Medical Imaging Systems). Volumetric assessment included left ventricular (LV) mass, LV/right ventricular (RV) end-diastolic/end-systolic volume, LV/RV stroke volume, and LV/RV ejection fraction (EF). Results of fully automated and manual analyses were compared. Regression analyses and receiver operator characteristics including area under the curve (AUC) calculation for prediction of the primary study endpoint cardiovascular (CV) death were performed. Results. Fully automated and manual assessment of LVEF revealed similar prediction of CV mortality in univariable (manual: hazard ratio (HR) 0.970 (95% CI 0.943–0.997) p = 0.032 ; automated: HR 0.967 (95% CI 0.939–0.995) p = 0.022 ) and multivariable analyses (model 1: (including significant univariable parameters) manual: HR 0.968 (95% CI 0.938–0.999) p = 0.043 ; automated: HR 0.963 [95% CI 0.933–0.995] p = 0.024 ; model 2: (including CV risk factors) manual: HR 0.962 (95% CI 0.920–0.996) p = 0.027 ; automated: HR 0.954 (95% CI 0.920–0.989) p = 0.011 ). There were no differences in AUC (LVEF fully automated: 0.686; manual: 0.661; p = 0.21 ). Absolute values of LV volumes differed significantly between automated and manual approaches ( p < 0.001 for all). Fully automated quantification resulted in a time saving of 10 minutes per patient. Conclusion. Fully automated biventricular volumetric assessments enable efficient and equal risk prediction compared to conventional manual approaches. In addition to significant time saving, this may provide the tools for optimized clinical management and stratification of patients with severe AS undergoing TAVR."],["dc.identifier.doi","10.1155/2022/1368878"],["dc.identifier.pii","1368878"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108521"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","1540-8183"],["dc.relation.issn","0896-4327"],["dc.title","Artificial Intelligence Enabled Fully Automated CMR Function Quantification for Optimized Risk Stratification in Patients Undergoing Transcatheter Aortic Valve Replacement"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1407"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","EuroIntervention"],["dc.bibliographiccitation.lastpage","1417"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Tichelbäcker, Tobias"],["dc.contributor.author","Bleckmann, Annalen"],["dc.contributor.author","Huenlich, Mark"],["dc.contributor.author","von der Ehe, Katrin"],["dc.contributor.author","Beuthner, Bo Eric"],["dc.contributor.author","Rueter, Karin"],["dc.contributor.author","Beißbarth, Tim"],["dc.contributor.author","Seipelt, Ralf"],["dc.contributor.author","Schoendube, Friedrich"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.date.accessioned","2017-09-07T11:46:19Z"],["dc.date.available","2017-09-07T11:46:19Z"],["dc.date.issued","2014"],["dc.description.abstract","Aims: MitraClip implantation is evolving as a potential alternative treatment to conventional surgery in high-risk patients with significant mitral regurgitation (MR). However, outcome predictors are under-investigated. The aim of this study was to identify predictors of midterm mortality and heart failure rehospitalisation after percutaneous mitral valve repair with MitraClip. Methods and results: A total of 150 consecutive patients were followed for a median of 463 days. Survival analyses were performed for baseline characteristics, risk scores and failure of acute procedural success (APS) defined as persisting MR grade 3+ or 4+. Univariate significant risk stratifiers were tested in multivariate analyses using a Cox proportional hazards model. Overall survival was 96% at 30 days, 79.5% at 12 months, and 62% at two years. Multivariate analysis identified APS failure (HR 2.13, p=0.02), NYHA Class IV at baseline (HR 2.11, p=0.01) and STS score >= 12 (HR 2.20, p<0.0001) as significant independent predictors of all-cause mortality, and APS failure (HR 2.31, p=0.01) and NYHA Class IV at baseline (HR 1.89, p=0.03) as significant independent predictors of heart failure rehospitalisation. Furthermore, a post-procedural significant decrease in hospitalisation rate could only be observed after successful interventions (0.89 +/- 1.07 per year before vs. 0.54 +/- 0.96 after implantation, p=0.01). Patients with severely dilated and overloaded ventricles who did not meet EVEREST II eligibility criteria were at higher risk of APS failure. Conclusions: The failure of acute procedural success proved to have the most important impact on outcome after MitraClip implantation."],["dc.identifier.doi","10.4244/EIJV9I12A238"],["dc.identifier.gro","3142144"],["dc.identifier.isi","000337011100009"],["dc.identifier.pmid","24972141"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/5033"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: Abbott Vascular"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Europa Edition"],["dc.relation.eissn","1969-6213"],["dc.relation.issn","1774-024X"],["dc.title","Failure of acute procedural success predicts adverse outcome after percutaneous edge-to-edge mitral valve repair with MitraClip"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","46"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Magnetic Resonance"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Backhaus, Sören Jan"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Beuthner, Bo Eric"],["dc.contributor.author","Topci, Rodi"],["dc.contributor.author","Wang, Xiaoqing"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Seidler, Tim"],["dc.contributor.author","Toischer, Karl"],["dc.contributor.author","Zeisberg, Elisabeth M."],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Jacobshagen, Claudius"],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Hasenfuß, Gerd P."],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2021-03-08T07:13:57Z"],["dc.date.available","2021-03-08T07:13:57Z"],["dc.date.issued","2020"],["dc.description.abstract","Myocardial fibrosis is a major determinant of outcome in aortic stenosis (AS). Novel fast real-time (RT) cardiovascular magnetic resonance (CMR) mapping techniques allow comprehensive quantification of fibrosis but have not yet been compared against standard techniques and histology."],["dc.identifier.doi","10.1186/s12968-020-00632-0"],["dc.identifier.pmid","32564773"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17418"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80477"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/50"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/359"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | D01: Erholung aus der Herzinsuffizienz – Einfluss von Fibrose und Transkriptionssignatur"],["dc.relation.issn","1532-429X"],["dc.relation.workinggroup","RG Hasenfuß"],["dc.relation.workinggroup","RG Uecker"],["dc.relation.workinggroup","RG E. Zeisberg (Kardiales Stroma)"],["dc.relation.workinggroup","RG Backhaus"],["dc.relation.workinggroup","RG Toischer (Kardiales Remodeling)"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1903"],["dc.bibliographiccitation.issue","20"],["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.lastpage","1914"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Beuthner, Bo Eric"],["dc.contributor.author","Topci, Rodi"],["dc.contributor.author","Vogelgesang, Anja"],["dc.contributor.author","Bleckmann, Annalen"],["dc.contributor.author","Sitte, Maren"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Backhaus, Sören Jan"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Seidler, Tim"],["dc.contributor.author","Kutschka, Ingo"],["dc.contributor.author","Toischer, Karl"],["dc.contributor.author","Zeisberg, Elisabeth Maria"],["dc.contributor.author","Jacobshagen, Claudius"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.date.accessioned","2020-06-16T13:21:30Z"],["dc.date.available","2020-06-16T13:21:30Z"],["dc.date.issued","2020-05-21"],["dc.description.abstract","Myocardial fibrosis (MF) might represent a key player in pathophysiology of heart failure in aortic stenosis (AS). We aimed to assess its impact on left ventricular (LV) remodelling, recovery, and mortality after transcatheter aortic valve implantation (TAVI) in different AS subtypes."],["dc.identifier.doi","10.1093/eurheartj/ehaa033"],["dc.identifier.pmid","32049275"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66367"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/438"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/341"],["dc.language.iso","en"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | D01: Erholung aus der Herzinsuffizienz – Einfluss von Fibrose und Transkriptionssignatur"],["dc.relation","SFB 1002 | D04: Bedeutung der Methylierung von RNA (m6A) und des Histons H3 (H3K4) in der Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.eissn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.relation.workinggroup","RG Hasenfuß"],["dc.relation.workinggroup","RG E. Zeisberg (Kardiales Stroma)"],["dc.relation.workinggroup","RG Backhaus"],["dc.relation.workinggroup","RG Toischer (Kardiales Remodeling)"],["dc.rights","CC BY-NC 4.0"],["dc.title","Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]