Clough, Dagmar

[["dc.bibliographiccitation.firstpage","215"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Endangered Species Research"],["dc.bibliographiccitation.lastpage","225"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Schwitzer, N."],["dc.contributor.author","Clough, Dagmar"],["dc.contributor.author","Zahner, H."],["dc.contributor.author","Kaumanns, W."],["dc.contributor.author","Kappeler, Peter"],["dc.contributor.author","Schwitzer, Christoph"],["dc.date.accessioned","2017-09-07T11:48:20Z"],["dc.date.available","2017-09-07T11:48:20Z"],["dc.date.issued","2010"],["dc.description.abstract","The parasite burden of an animal population has frequently been used as an indicator of the stress level to which the population is exposed. Primates inhabiting small forest fragments are more likely to experience human contact, reduced food availability and restricted ranging—any or all of which may contribute to a higher parasite prevalence—than populations inhabiting intact primary forest. Recent and ongoing human exploitation of otherwise intact forest may also affect disease burden and parasite transmission in primates. The parasites of blue-eyed black lemurs Eulemur flavifrons have not as yet been subject to scientific research. This paper describes the various parasites found in E. flavifrons and shows parasite prevalence in lemur groups living in differently degraded fragments of the Ankarafa Forest in Sahamalaza National Park, northwest Madagascar. We analysed 166 faecal samples of E. flavifrons inhabiting primary forest and 168 from groups inhabiting secondary forest. In addition, faecal samples and ectoparasites were collected from 18 immobilised lemurs. Forty-three (12.9%) samples contained parasite eggs (Lemuricola spp. and Callistoura spp.) or oocysts. Ten (55.6%) of the 18 samples from immobilised lemurs contained adult Lemuricola spp. Parasite prevalence was significantly higher in secondary than in primary forest, at 7.9 and 4.8% of all positive samples, respectively. Prevalence was high when compared to other studies on parasite load in wild lemurs, suggesting that in our survey area, E. flavifrons were generally under pressure, possibly due to the high degree of fragmentation and degradation of the remaining forest habitat."],["dc.identifier.doi","10.3354/esr00304"],["dc.identifier.gro","3150783"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9074"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7573"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","1863-5407"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject","Eulemur flavifrons; Primary forest; Secondary forest; Lemuricola; Callistoura; Seasonality"],["dc.title","Parasite prevalence in blue-eyed black lemurs Eulemur flavifrons in differently degraded forest fragments"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","9"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Frontiers in Zoology"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Clough, Dagmar"],["dc.contributor.author","Kappeler, Peter"],["dc.contributor.author","Walter, Lutz"],["dc.date.accessioned","2017-09-07T11:48:58Z"],["dc.date.available","2017-09-07T11:48:58Z"],["dc.date.issued","2011"],["dc.description.abstract","BackgroundSusceptibility to parasite infection affects fitness-related processes, such as mate choice and survival, yet its genetic regulation remains poorly understood. Interleukin-4 (IL4) plays a central role in the humoral immune defence against nematode parasite infections, inducing IgE switch and regulation of worm expulsion from the intestines. The evolutionary and functional significance of single nucleotide polymorphisms (SNPs) in IL4-genes is known, yet empirical information on the effect of IL4 SNPs on gastro-intestinal infections is lacking. Using samples from a population of wild red-fronted lemurs (Eulemur fulvus rufus, Primates: Lemuridae), from western Madagascar, we explored the association of IL4-gene promoter polymorphisms with nematode infections and investigated a possible functional role of the IL4 polymorphism on male reproductive success.ResultsUsing sequence analyses of lemur DNA we detected a new SNP in the IL4 gene promoter area. Carriers of the genotype T/T showed higher nematode infection intensities than individuals of genotypes C/T and C/C. Genetic population analyses using data from more than 10 years, suggested higher reproductive success of T/T males than expected.ConclusionsOur results suggest a regulatory effect of an IL4 gene promoter polymorphism on the intensity of parasite infections in a natural population of red-fronted lemurs, with a seemingly disadvantageous genotype represented in low frequencies. Long-term population analyses, however, point in the direction of a negative frequency-dependent association, giving a fitness advantage to the rare genotype. Due to low frequencies of the genotype in question conclusive evidence of a functional role of IL4 polymorphism cannot be drawn here; still, we suggest the use of IL4 polymorphism as a new molecular tool for quick assessment of individual genetic constitution with regard to nematode infection intensities, contributing to a better understanding of the actual components of the immune response that mediate protection against gastro-intestinal parasites."],["dc.identifier.doi","10.1186/1742-9994-8-9"],["dc.identifier.gro","3150917"],["dc.identifier.pmid","21501512"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6364"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7717"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","1742-9994"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Genetic regulation of parasite infection: empirical evidence of the functional significance of an IL4 gene SNP on nematode infections in wild primates"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","859"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","International Journal of Primatology"],["dc.bibliographiccitation.lastpage","875"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Clough, Dagmar"],["dc.contributor.author","Heistermann, Michael"],["dc.contributor.author","Kappeler, Peter"],["dc.date.accessioned","2017-09-07T11:49:00Z"],["dc.date.available","2017-09-07T11:49:00Z"],["dc.date.issued","2009"],["dc.description.abstract","Researchers studying individual variation in conspicuous skin coloration in primates have suggested that color indicates male quality. Although primate fur color can also be flamboyant, the potential condition dependence and thus signaling function of fur remains poorly studied. We studied sources of variation in sexually dichromatic facial hair coloration in red-fronted lemurs (Eulemur fulvus rufus). We collected data on 13 adult males in Kirindy Forest, Madagascar, during two study periods in 2006 and 2007, to determine whether variation in facial hair coloration correlates with male age, rank, androgen status, and reproductive success. We quantified facial hair coloration via standardized digital photographs of each male, assessed androgen status using fecal hormone measurements, and obtained data on reproductive success through genetic paternity analyses. Male facial hair coloration showed high individual variation, and baseline coloration was related to individual androgen status but not to any other parameter tested. Color did not reflect rapid androgen changes during the mating season. However, pronounced long-term changes in androgen levels between years were accompanied by changes in facial hair coloration. Our data suggest that facial hair coloration in red-fronted lemur males is under proximate control of androgens and may provide some information about male quality, but it does not correlate with dominance rank or male reproductive success."],["dc.identifier.doi","10.1007/s10764-009-9379-5"],["dc.identifier.gro","3150939"],["dc.identifier.pmid","19946601"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/4161"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7742"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","0164-0291"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Individual Facial Coloration in Male Eulemur fulvus rufus: A Condition-dependent Ornament?"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]